Clinical Trials

Showing trials with last updates posted in 2025.

NCT04677569 | ACTIVE_NOT_RECRUITING | PHASE3
425 Participants

Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-04-01
Completion: 2025-11-21
Conditions
Mycobacterium Infections, Nontuberculous
Interventions
DRUG
No Results Yet
NCT04674969 | RECRUITING
5000 Participants

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-03-29
Completion: 2028-01-31
Conditions
Peripheral Vascular Diseases
Interventions
DEVICE
No Results Yet
NCT04670744 | RECRUITING
1000000 Participants

Identification of Outcome Relevant Indicators in Routine Data

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2020-12-03
Completion: 2025-12-31
Conditions
Anesthesiological Risk Reduction Intensive Care Risk Reduction
No Results Yet
NCT04644770 | ACTIVE_NOT_RECRUITING | PHASE1
144 Participants

A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-11-12
Completion: 2027-10-01
Conditions
Prostatic Neoplasms Adenocarcinoma
Interventions
DRUG RADIATION
No Results Yet
NCT04639778 | RECRUITING | NA
390 Participants

Monitoring the Weight Evolution Using a Connected Scale

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-03-25
Completion: 2026-12-31
Conditions
Bariatric Surgery Long Term Follow-Up Weight Regain
Interventions
OTHER
No Results Yet
NCT04620070 | COMPLETED | NA
221 Participants

ON-SCENE Initiation of Extracorporeal CardioPulmonary Resuscitation During Refractory Out-of-Hospital Cardiac Arrest

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-10-15
Completion: 2025-07-01
Conditions
Extracorporeal Membrane Oxygenation Cardiac Arrest
Interventions
PROCEDURE
No Results Yet
NCT04600804 | COMPLETED
200 Participants

The Role of 18F-FDG-PET for Staging and Prognostication

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2020-10-30
Completion: 2023-10-26
Conditions
Mantle Cell Lymphoma
No Results Yet
NCT04592913 | ACTIVE_NOT_RECRUITING | PHASE3
957 Participants

Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-11-17
Completion: 2024-12-20
Conditions
Gastrointestinal Neoplasms Esophagogastric Junction
Interventions
DRUG
No Results Yet
NCT04592523 | RECRUITING
257 Participants

A Study of Usage of Brigatinib in the Treatment of Adult Participants for Approved Indications In South Korea

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2019-09-05
Completion: 2026-08-26
Conditions
Carcinoma, Non-Small-Cell Lung Anaplastic Lymphoma Kinase
Interventions
OTHER
No Results Yet
NCT04588883 | COMPLETED | NA
843 Participants

Strengthening Families Living With HIV in Kenya

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-09-28
Completion: 2025-07-15
Conditions
ART Hiv Trust Depression, Anxiety PTSD Adherence, Medication
Interventions
BEHAVIORAL
No Results Yet
NCT04580420 | RECRUITING | PHASE2
28 Participants

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-04-15
Completion: 2031-12-30
Conditions
Primary Hyperoxaluria Type 1 End Stage Renal Disease
Interventions
DRUG
No Results Yet
NCT04575688 | ENROLLING_BY_INVITATION | PHASE4
100 Participants

Periarticular Injection Versus Popliteal Block

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-07-13
Completion: 2026-09-30
Conditions
Foot Surgery Ankle Surgery
Interventions
DRUG
No Results Yet
NCT04572763 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
48 Participants

Copanlisib Plus Venetoclax in R/R DLBCL

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-09-08
Completion: 2026-04-01
Conditions
Diffuse Large B Cell Lymphoma Relapsed Diffuse Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT04561518 | RECRUITING
1500 Participants

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2020-11-23
Completion: 2030-09-01
Conditions
Transthyretin-Mediated Amyloidosis ATTR Amyloidosis
No Results Yet
NCT04557462 | RECRUITING | PHASE3
540 Participants

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-09-20
Completion: 2032-10-25
Conditions
Primary IgA Nephropathy
Interventions
DRUG
No Results Yet
NCT04548180 | COMPLETED
68 Participants

Genome-Wide Assocation Study in Patients With Brain Injury Associated Fatigue and Altered Cognition (BIAFAC)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-06-21
Completion: 2024-01-18
Conditions
Traumatic Brain Injury
No Results Yet
NCT04544449 | ACTIVE_NOT_RECRUITING | PHASE3
985 Participants

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-10-26
Completion: 2025-09-17
Conditions
Multiple Sclerosis, Primary Progressive
Interventions
DRUG
No Results Yet
NCT04544267 | TERMINATED | PHASE3
100 Participants

Study on a High-Dose Quadrivalent Influenza Vaccine Compared With Standard-Dose Quadrivalent Influenza Vaccine in Children 6 Months Through 35 Months of Age

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-09-15
Completion: 2021-06-02
Conditions
Influenza
Interventions
BIOLOGICAL
NCT04539041 | COMPLETED | PHASE1
59 Participants

Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-02-16
Completion: 2024-10-17
Conditions
Progressive Supranuclear Palsy (PSP)
Interventions
DRUG
No Results Yet
NCT04536038 | COMPLETED | NA
5176 Participants

Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-10-05
Completion: 2023-05-31
Conditions
Peripheral Artery Disease
Interventions
BEHAVIORAL
NCT04530890 | RECRUITING | NA
1000 Participants

Interest of Circulating Tumor DNA in Digestive and Gynecologic/Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-03-08
Completion: 2032-03-31
Conditions
Breast Cancer Digestive Cancer Gynecologic Cancer Circulating Tumor DNA Exosomes
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04530526 | COMPLETED | NA
26 Participants

Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2019-07-12
Completion: 2023-06-30
Conditions
Post-Mastectomy Chronic Pain Syndrome
Interventions
PROCEDURE
NCT04529772 | ACTIVE_NOT_RECRUITING | PHASE3
611 Participants

A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-10-08
Completion: 2027-02-01
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT04520490 | ACTIVE_NOT_RECRUITING | PHASE3
63 Participants

Brain Activation and Satiety in Children 2

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-01-28
Completion: 2025-02-21
Conditions
Childhood Obesity
Interventions
BEHAVIORAL DRUG
No Results Yet
NCT04517838 | RECRUITING
230 Participants

Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2020-07-31
Completion: 2028-07-27
Conditions
Breast Adenocarcinoma HER2-Positive Breast Carcinoma Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8
Interventions
PROCEDURE
No Results Yet
NCT04511078 | RECRUITING | PHASE2
25 Participants

Phase II Panitumumab-IRDye800 in Head & Neck Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-04-02
Completion: 2030-12-31
Conditions
Head and Neck Cancer
Interventions
DRUG
No Results Yet
NCT04503122 | COMPLETED
116 Participants

Baroreflex Sensitivity in Patients Undergoing Ablation of Atrial Fibrillation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-06-22
Completion: 2025-11-13
Conditions
Paroxysmal Atrial Fibrillation
Interventions
PROCEDURE
No Results Yet
NCT04501081 | RECRUITING
1100 Participants

Natural History of Autosomal Dominant Hearing Loss

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-02-09
Completion: 2029-08-21
Conditions
Hearing Loss
No Results Yet
NCT04497857 | COMPLETED | NA
74 Participants

Academic-Community EPINET (AC-EPINET)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-03-16
Completion: 2025-07-29
Conditions
Schizophrenia Schizoaffective Disorder Schizophreniform Disorders Major Depression With Psychotic Features Bipolar Disorder With Psychotic Features
Interventions
OTHER
No Results Yet
NCT04451863 | ACTIVE_NOT_RECRUITING | PHASE1
45 Participants

Analgesic and Subjective Effects of Terpenes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-12-15
Completion: 2025-11-12
Conditions
Pain Abuse, Drug
Interventions
DRUG
No Results Yet
NCT04449549 | RECRUITING | PHASE2
82 Participants

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-08-24
Completion: 2026-04-02
Conditions
Neoplasms
Interventions
DRUG
No Results Yet
NCT04431024 | RECRUITING
800 Participants

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-03-30
Completion: 2038-06-30
Conditions
Familial Cancer BRCA1-Associated Protein-1 (BAP1) Mutations Tumor Predisposition Syndrome (TPDS) Mesothelioma
No Results Yet
NCT04362826 | NOT_YET_RECRUITING | NA
100 Participants

Study to Investigate Efficacy of a Novel Probiotic on the Bacteriome and Mycobiome of Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-02-28
Completion: 2026-12-31
Conditions
Breast Cancer
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT04339764 | RECRUITING | PHASE1/PHASE2
20 Participants

Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-09-23
Completion: 2029-05-31
Conditions
Dry Age-Related Macular Degeneration Geographic Atrophy
Interventions
DRUG
No Results Yet
NCT04305431 | RECRUITING | NA
55 Participants

Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-02-25
Completion: 2026-12-19
Conditions
Diet Cooking
Interventions
BEHAVIORAL
No Results Yet
NCT04294693 | ACTIVE_NOT_RECRUITING
1000 Participants

Total Joint Arthroplasty in a Pediatric Population

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2019-06-03
Completion: 2050-03-31
Conditions
Total Joint Arthroplasty
No Results Yet
NCT04294160 | TERMINATED | PHASE1
122 Participants

A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-07-22
Completion: 2024-09-25
Conditions
BRAF V600 Colorectal Cancer
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT04271774 | ACTIVE_NOT_RECRUITING
600 Participants

Genome Environment Microbiome and Metabolome in Autism Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2019-07-01
Completion: 2025-12-31
Conditions
Autism Spectrum Disorder
No Results Yet
NCT04255615 | RECRUITING | NA
4000 Participants

Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-02-12
Completion: 2029-01-31
Conditions
Infertility in Vitro Fertilization (IVF) ART
Interventions
OTHER
No Results Yet
NCT04244877 | WITHDRAWN | PHASE3
0 Participants

Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-09-15
Completion: 2023-05-01
Conditions
Cirrhosis, Liver Minimal Hepatic Encephalopathy Small Intestinal Bacterial Overgrowth Gastrointestinal Motility Disorder
Interventions
DRUG
No Results Yet
Previous
Sorted by latest updates
Next
Showing 40 trials per page