Clinical Trials
Showing trials with last updates posted in 2025.
99
Participants
Pathophysiology of Acute Pain in Patients With Sickle Cell Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2017-03-13
Completion:
2019-12-09
Conditions
Sickle Cell Disease
No Results Yet
1050
Participants
Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2017-01-06
Completion:
2029-08-06
Conditions
Ovarian Cancer
Triple-Negative Breast Cancer
Head and Neck Cancer
Cervical Cancer
Sarcoma
Interventions
PROCEDURE
No Results Yet
80
Participants
His Bundle Pacing in Bradycardia and Heart Failure
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2016-10-31
Completion:
2026-12-31
Conditions
Bradycardia
Heart Failure
Interventions
PROCEDURE
No Results Yet
669
Participants
Study of Durvalumab Alone or Chemotherapy for Patients With Advanced Non Small-Cell Lung Cancer (PEARL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2017-01-02
Completion:
2022-10-27
Conditions
Non Small Cell Lung Carcinoma NSCLC
Interventions
DRUG
51
Participants
A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-08-09
Completion:
2026-04-01
Conditions
Juvenile Idiopathic Arthritis
Interventions
DRUG
No Results Yet
4000
Participants
Neurovascular Product Surveillance Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2016-12-31
Completion:
2032-08-31
Conditions
Intracranial Aneurysm
Stroke, Ischemic
Interventions
DEVICE
No Results Yet
11
Participants
FES in Young Children With Perinatal Stroke
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-01-01
Completion:
2020-12-10
Conditions
Cerebral Palsy
Interventions
DEVICE
BEHAVIORAL
No Results Yet
160
Participants
Diffusion MRI in Heart Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2017-06-30
Completion:
2027-12-31
Conditions
Myocardial Infarction
Heart Failure
Left Ventricular Hypertrophy
Interventions
DEVICE
DRUG
No Results Yet
110
Participants
A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2017-10-12
Completion:
2029-05-31
Conditions
Chronic Lymphocytic Leukemia (CLL)
Small Lymphocytic Lymphoma (SLL)
Interventions
DRUG
No Results Yet
20
Participants
Contrast-Enhanced Ultrasound for Kidney Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-02-21
Completion:
2022-06-30
Conditions
Kidney Transplantation
Interventions
DRUG
No Results Yet
51
Participants
Small Intestinal Bacterial Overgrowth Obese
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2016-05-27
Completion:
2022-10-07
Conditions
Gastric Bypass
Blind Loop Syndrome
Bacterial Overgrowth Syndrome
Chromatography, Gas
Interventions
PROCEDURE
No Results Yet
15000
Participants
A Longitudinal Observational Study of Patients With Nonalcoholic Steatohepatitis (NASH) and Related Conditions Across the Entire Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2016-07-31
Completion:
2036-07-31
Conditions
Nonalcoholic Fatty Liver
Nonalcoholic Steatohepatitis
No Results Yet
60
Participants
Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2017-01-30
Completion:
2025-10-27
Conditions
Acute Myeloid Leukemia
Interventions
PROCEDURE
DRUG
No Results Yet
5000
Participants
Clinical and Molecular Studies in Families With Inherited Eye Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2016-10-04
Completion:
2032-01-01
Conditions
Inherited Eye Disease
No Results Yet
132
Participants
Impact of Fat-free Mass in the Carboplatin Calculated Dose and Chemotherapeutic Toxicity in Patients With Advanced NSCLC
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2016-02-29
Completion:
2026-12-31
Conditions
Lung Cancer
Sarcopenia
Toxicity
Interventions
DRUG
No Results Yet
69
Participants
Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2016-05-03
Completion:
2026-06-30
Conditions
Solid Tumors
CNS Tumors
Interventions
DRUG
No Results Yet
20000
Participants
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2015-09-16
Completion:
2028-12-31
Conditions
Genetic Disease
No Results Yet
156
Participants
A Multi-center Outcomes Clinical Study of the PyroTITAN™ HRA Shoulder Implant in Humeral Head Resurfacing
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2010-08-31
Completion:
2023-09-30
Conditions
Arthritis
Interventions
DEVICE
900
Participants
Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2015-03-15
Completion:
2099-12-31
Conditions
Healthy Volunteers
Non-Healthy/Non-Frail
Frail
No Results Yet
2
Participants
Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry Protocol
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2014-12-19
Completion:
2018-08-20
Conditions
Inborn Errors of Metabolism
Pregnancy
Acidemias
No Results Yet
29
Participants
Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2013-10-31
Completion:
2016-10-31
Conditions
Hematuria
Nephrolithiasis
Cancer of Urinary Tract
Ureteropelvic Junction Obstruction
Interventions
DEVICE
No Results Yet
100
Participants
Genomic Profiling in Recommending Treatment for Patients With Metastatic Solid Tumors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2014-07-28
Completion:
2026-12-31
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
GENETIC
OTHER
No Results Yet
10
Participants
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2014-12-08
Completion:
2017-09-05
Conditions
Neurofibromatosis
MPNST
Interventions
PROCEDURE
DRUG
No Results Yet
36
Participants
Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2014-08-21
Completion:
2023-02-14
Conditions
Brain Tumor
Interventions
BEHAVIORAL
No Results Yet
85
Participants
T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2014-10-23
Completion:
2027-10-23
Conditions
Advanced Non-Small Cell Lung Cancer
Squamous Cell Carcinoma
Advanced NSCLC
Adenosquamous Carcinoma
Adenocarcinoma
Interventions
DRUG
BIOLOGICAL
No Results Yet
70
Participants
A Study of Novel Immune Modulating Biomarkers in Patients With Spondyloarthritis With Axial Involvement
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2013-01-31
Completion:
2025-12-18
Conditions
Spondyloarthritis
No Results Yet
2008
Participants
Comprehensive Care Physician: Integrated Inpatient and Outpatient Care for Patients at High Risk of Hospitalization
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2012-11-30
Completion:
2026-01-31
Conditions
Medicare Patients
High Risk of Hospitalizations
Interventions
OTHER
No Results Yet
24
Participants
Healthy Adult Volunteer Study of Intraosseous Infusion Using the Sternum
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2013-04-30
Completion:
2013-05-31
Conditions
Intraosseous Vascular Access
Interventions
DEVICE
100
Participants
Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2013-06-10
Completion:
2027-11-01
Conditions
Lymphangioleiomyomatosis
Interventions
DRUG
PROCEDURE
No Results Yet
300
Participants
Intravenous Gammaglobulin for Sickle Cell Pain Crises
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2008-11-30
Completion:
2024-12-18
Conditions
Sickle Cell Disease
Pain
Interventions
DRUG
OTHER
No Results Yet
657
Participants
An Immuno-therapy Study to Evaluate the Effectiveness, Safety and Tolerability of Nivolumab or Nivolumab in Combination With Other Agents in Patients With Advanced Liver Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2012-10-30
Completion:
2024-11-12
Conditions
Hepatocellular Carcinoma
Interventions
BIOLOGICAL
DRUG
67
Participants
A Prospective Non-concurrent Controlled Evaluation of Open and MAS® PLIF
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2012-06-30
Completion:
2014-06-30
Conditions
Lumbar Degenerative Disc Disease
Interventions
PROCEDURE
No Results Yet
800
Participants
Long Term Effects On Recipients of Hematopoietic Stem Cell Transplantation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
1995-01-31
Completion:
2099-01-31
Conditions
Blood and Marrow Transplant (BMT)
No Results Yet
197
Participants
Aceto-whitening in the Assessment of Gastrointestinal Neoplasia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2010-11-23
Completion:
2011-09-30
Conditions
Barrett Esophagus
Barrett Metaplasia
Barrett Oesophagitis With Dysplasia
Barrett Adenocarcinoma
Interventions
PROCEDURE
No Results Yet
100000
Participants
Product Surveillance Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2012-01-31
Completion:
2040-01-31
Conditions
Cardiac Rhythm Disorders
Urological Disorders
Neurological Disorders
Cardiovascular Disorders
Digestive Disorders
Intracranial Aneurysm
Mechanical Circulatory Support
Respiratory Therapy
Aortic, Peripheral Vascular and Venous Disorders
Minimally Invasive Surgical Procedures
Diagnostic Techniques and Procedures
Surgical Procedures, Operative
Renal Insufficiency
Neurovascular
Coronary Artery Disease
Ear, Nose and Throat Disorder
No Results Yet
10000
Participants
Prospective Screening for Breast Cancer-related Lymphedema
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2009-08-31
Completion:
2026-10-31
Conditions
Lymphedema
Interventions
OTHER
No Results Yet
323
Participants
Multimodality Neuromonitoring in XLIF
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2011-10-31
Completion:
2013-12-31
Conditions
Degeneration of Lumbar Intervertebral Disc
No Results Yet
62
Participants
Imaging Biomarkers in Parkinson s Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2012-01-24
Conditions
Parkinson Disease
No Results Yet
2
Participants
A Clinical Trial Evaluating a Total Disc Replacement in Patients With Cervical Disc Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2010-05-31
Completion:
2013-12-31
Conditions
Cervical Disc Disease
Interventions
DEVICE
No Results Yet
140
Participants
Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2011-09-08
Completion:
2028-12-31
Conditions
KSHV Inflammatory Cytokine Syndrome (KICS)
KSHV
HHV-8
Interventions
DRUG
OTHER
No Results Yet
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