Clinical Trials
Showing trials with last updates posted in 2025.
900
Participants
Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2015-03-15
Completion:
2099-12-31
Conditions
Healthy Volunteers
Non-Healthy/Non-Frail
Frail
No Results Yet
2
Participants
Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry Protocol
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2014-12-19
Completion:
2018-08-20
Conditions
Inborn Errors of Metabolism
Pregnancy
Acidemias
No Results Yet
1000
Participants
Adaptive Optics Retinal Imaging
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2015-02-20
Completion:
2028-03-31
Conditions
Eye Diseases
Healthy Volunteers
No Results Yet
29
Participants
Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2013-10-31
Completion:
2016-10-31
Conditions
Hematuria
Nephrolithiasis
Cancer of Urinary Tract
Ureteropelvic Junction Obstruction
Interventions
DEVICE
No Results Yet
100
Participants
Genomic Profiling in Recommending Treatment for Patients With Metastatic Solid Tumors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2014-07-28
Completion:
2026-12-31
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
GENETIC
OTHER
No Results Yet
10
Participants
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2014-12-08
Completion:
2017-09-05
Conditions
Neurofibromatosis
MPNST
Interventions
PROCEDURE
DRUG
No Results Yet
36
Participants
Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2014-08-21
Completion:
2023-02-14
Conditions
Brain Tumor
Interventions
BEHAVIORAL
No Results Yet
2000
Participants
Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2014-05-28
Completion:
2028-12-31
Conditions
Non-Small Cell Lung Cancer
Small Cell Lung Cancer
Extrapulmonary Small Cell Cancer
Pulmonary Neuroendocrine Tumors
Thymic Epithelial Tumors
No Results Yet
85
Participants
T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2014-10-23
Completion:
2027-10-23
Conditions
Advanced Non-Small Cell Lung Cancer
Squamous Cell Carcinoma
Advanced NSCLC
Adenosquamous Carcinoma
Adenocarcinoma
Interventions
DRUG
BIOLOGICAL
No Results Yet
300
Participants
Deep Brain Stimulation Therapy in Movement Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2014-04-02
Completion:
2030-12-01
Conditions
Parkinson's Disease
Interventions
DEVICE
No Results Yet
70
Participants
A Study of Novel Immune Modulating Biomarkers in Patients With Spondyloarthritis With Axial Involvement
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2013-01-31
Completion:
2025-12-18
Conditions
Spondyloarthritis
No Results Yet
24
Participants
Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2015-07-02
Completion:
2025-06-05
Conditions
Incomplete Spinal Cord Injury
Muscular Dystrophy
Spina Bifida
Cerebral Palsy
Interventions
DEVICE
No Results Yet
2008
Participants
Comprehensive Care Physician: Integrated Inpatient and Outpatient Care for Patients at High Risk of Hospitalization
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2012-11-30
Completion:
2026-01-31
Conditions
Medicare Patients
High Risk of Hospitalizations
Interventions
OTHER
No Results Yet
1800
Participants
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2013-07-21
Completion:
2029-06-30
Conditions
Colorectal Neoplasms
Gastric Neoplasms
Cholangiocarcinoma
Bile Duct Cancer
Pancreas Cancer
No Results Yet
16
Participants
NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2013-06-11
Completion:
2015-09-08
Conditions
Solid Tumors
Brain Tumors
Sarcoma
Pediatric Cancers
Neuroblastoma
Interventions
BIOLOGICAL
No Results Yet
24
Participants
Healthy Adult Volunteer Study of Intraosseous Infusion Using the Sternum
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2013-04-30
Completion:
2013-05-31
Conditions
Intraosseous Vascular Access
Interventions
DEVICE
100
Participants
Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2013-06-10
Completion:
2027-11-01
Conditions
Lymphangioleiomyomatosis
Interventions
DRUG
PROCEDURE
No Results Yet
400
Participants
The NIH MINI Study: Metabolism, Infection, and Immunity in Inborn Errors of Metabolism
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2012-12-31
Completion:
2025-12-31
Conditions
Oxidative Phosphorylation Deficiencies
Electron Transport Chain Disorders, Mitochondrial
Mitochondrial Disorders
Leigh Disease
No Results Yet
300
Participants
Intravenous Gammaglobulin for Sickle Cell Pain Crises
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2008-11-30
Completion:
2024-12-18
Conditions
Sickle Cell Disease
Pain
Interventions
DRUG
OTHER
No Results Yet
75
Participants
Bisnorcymserine in Healthy Adult Volunteers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2013-01-29
Completion:
2018-09-21
Conditions
Healthy Volunteers
Interventions
DRUG
OTHER
No Results Yet
117
Participants
The COX-2 Gene and the Immune System
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2013-05-02
Conditions
Allergic Inflammation
Asthma
No Results Yet
657
Participants
An Immuno-therapy Study to Evaluate the Effectiveness, Safety and Tolerability of Nivolumab or Nivolumab in Combination With Other Agents in Patients With Advanced Liver Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2012-10-30
Completion:
2024-11-12
Conditions
Hepatocellular Carcinoma
Interventions
BIOLOGICAL
DRUG
67
Participants
A Prospective Non-concurrent Controlled Evaluation of Open and MAS® PLIF
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2012-06-30
Completion:
2014-06-30
Conditions
Lumbar Degenerative Disc Disease
Interventions
PROCEDURE
No Results Yet
800
Participants
Long Term Effects On Recipients of Hematopoietic Stem Cell Transplantation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
1995-01-31
Completion:
2099-01-31
Conditions
Blood and Marrow Transplant (BMT)
No Results Yet
25
Participants
AAV2-GDNF for Advanced Parkinson s Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2013-03-13
Completion:
2022-02-04
Conditions
Parkinson's Disease
Interventions
GENETIC
No Results Yet
197
Participants
Aceto-whitening in the Assessment of Gastrointestinal Neoplasia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2010-11-23
Completion:
2011-09-30
Conditions
Barrett Esophagus
Barrett Metaplasia
Barrett Oesophagitis With Dysplasia
Barrett Adenocarcinoma
Interventions
PROCEDURE
No Results Yet
100000
Participants
Product Surveillance Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2012-01-31
Completion:
2040-01-31
Conditions
Cardiac Rhythm Disorders
Urological Disorders
Neurological Disorders
Cardiovascular Disorders
Digestive Disorders
Intracranial Aneurysm
Mechanical Circulatory Support
Respiratory Therapy
Aortic, Peripheral Vascular and Venous Disorders
Minimally Invasive Surgical Procedures
Diagnostic Techniques and Procedures
Surgical Procedures, Operative
Renal Insufficiency
Neurovascular
Coronary Artery Disease
Ear, Nose and Throat Disorder
No Results Yet
10000
Participants
Prospective Screening for Breast Cancer-related Lymphedema
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2009-08-31
Completion:
2026-10-31
Conditions
Lymphedema
Interventions
OTHER
No Results Yet
45
Participants
The Role of Endocannabinoids in Insulin Production and Action
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2012-01-05
Completion:
2014-10-06
Conditions
Healthy Volunteers
Interventions
OTHER
DRUG
No Results Yet
323
Participants
Multimodality Neuromonitoring in XLIF
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2011-10-31
Completion:
2013-12-31
Conditions
Degeneration of Lumbar Intervertebral Disc
No Results Yet
62
Participants
Imaging Biomarkers in Parkinson s Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2012-01-24
Conditions
Parkinson Disease
No Results Yet
2
Participants
A Clinical Trial Evaluating a Total Disc Replacement in Patients With Cervical Disc Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2010-05-31
Completion:
2013-12-31
Conditions
Cervical Disc Disease
Interventions
DEVICE
No Results Yet
930
Participants
Cell Collection to Study Eye Diseases
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2011-09-07
Conditions
Retinal Disease
AMD
Retinal Degeneration
Retinitis Pigmentosa
No Results Yet
140
Participants
Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2011-09-08
Completion:
2028-12-31
Conditions
KSHV Inflammatory Cytokine Syndrome (KICS)
KSHV
HHV-8
Interventions
DRUG
OTHER
No Results Yet
4000
Participants
Screening Volunteers for Clinical Trials
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2011-08-16
Conditions
Screening
No Results Yet
8079
Participants
SpineTRACK Registry - Spinal Outcomes Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2011-03-31
Completion:
2016-12-06
Conditions
Vertebra; Degeneration
Spinal Trauma
Spinal Deformity
Interventions
PROCEDURE
No Results Yet
1100
Participants
Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2011-05-06
Conditions
Diabetes
Cardiovascular Disease
No Results Yet
50
Participants
Powered Bone Marrow Aspiration and Core Biopsy System Compared to Manual Devices
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2010-01-31
Completion:
2010-07-31
Conditions
Bone Marrow Biopsy Procedures
Interventions
DEVICE
95
Participants
Molecular Immunohematology in Ethiopian Sub-Populations
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2012-11-03
Conditions
Immunohematology
No Results Yet
580
Participants
Environmental Risk Factors for the Anti-synthetase Syndrome
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2011-02-09
Conditions
Myositis
Dermatomyositis
Polymyositis
Juvenile Dermatomyositis
Juvenile Polymyositis
No Results Yet
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