Clinical Trials

Showing trials with last updates posted in 2025.

NCT05290246 | ACTIVE_NOT_RECRUITING | NA
115 Participants

TRE in Type 2 Diabetes (See Food Study 3)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-05-27
Completion: 2025-12-12
Conditions
Type2Diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT05274243 | COMPLETED | PHASE2
32 Participants

2-HOBA Phase 2 Clinical Trial in Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-08-09
Completion: 2025-05-28
Conditions
Rheumatoid Arthritis
Interventions
DRUG OTHER
No Results Yet
NCT05259501 | COMPLETED | NA
15 Participants

Remote Methadone Ingestion Surveillance Trial (RMIST)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-15
Completion: 2025-03-13
Conditions
Opioid Use Disorder
Interventions
OTHER
No Results Yet
NCT05245669 | COMPLETED | PHASE1
207 Participants

Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of Biosimilar Denosumab With Prolia® in Healthy Adult Male Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-01-10
Completion: 2024-05-22
Conditions
Healthy Male Subjects
Interventions
BIOLOGICAL
NCT05239143 | ACTIVE_NOT_RECRUITING | PHASE1
180 Participants

P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-15
Completion: 2026-04-30
Conditions
Breast Cancer Ovarian Cancer Non Small Cell Lung Cancer Colorectal Cancer Pancreatic Cancer Renal Cell Carcinoma Nasopharyngeal Cancer Head and Neck Squamous Cell Carcinoma Gastric Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05217849 | ACTIVE_NOT_RECRUITING | NA
80 Participants

Multi-domain Online Therapeutic Investigation Of Neurocognition (MOTION)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-15
Completion: 2025-12-31
Conditions
Mild Cognitive Impairment Subjective Memory Decline
Interventions
BEHAVIORAL
No Results Yet
NCT05211895 | RECRUITING | PHASE3
860 Participants

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-18
Completion: 2028-07-12
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG OTHER
No Results Yet
NCT05197049 | ACTIVE_NOT_RECRUITING | PHASE3
350 Participants

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-01-19
Completion: 2023-07-04
Conditions
Crohn Disease
Interventions
DRUG
NCT05192434 | ACTIVE_NOT_RECRUITING | NA
219 Participants

Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-06-17
Completion: 2026-12-31
Conditions
HIV Infections Opioid Use Trauma, Psychological
Interventions
BEHAVIORAL
No Results Yet
NCT05182879 | RECRUITING
740 Participants

Evaluation of Frail Elderly in Ambulatory Primary Care

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2019-02-12
Completion: 2026-01-31
Conditions
Frailty
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05160701 | ACTIVE_NOT_RECRUITING | NA
300 Participants

Bringing Health Home

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-05-09
Completion: 2025-08-15
Conditions
Mental Disorders, Severe
Interventions
OTHER
No Results Yet
NCT05150210 | ACTIVE_NOT_RECRUITING | NA
32 Participants

SP Thoracic IDE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-07-20
Completion: 2023-06-16
Conditions
Primary Lung Cancer Benign Lung Disease Thymoma Myasthenia Gravis
Interventions
DEVICE
NCT05147792 | RECRUITING | NA
1600 Participants

The CONFORM Pivotal Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-05-26
Completion: 2028-06-30
Conditions
Atrial Fibrillation Stroke
Interventions
DEVICE
No Results Yet
NCT05137743 | ACTIVE_NOT_RECRUITING | NA
80 Participants

Pilot Test of Apnea and Insomnia Relief for Veterans With Gulf War Illness

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-15
Completion: 2025-12-31
Conditions
Gulf War Illness
Interventions
BEHAVIORAL
No Results Yet
NCT05133245 | ENROLLING_BY_INVITATION
50 Participants

PHACE - Prospective Genetic Investigation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-11-01
Completion: 2026-11-01
Conditions
PHACE Syndrome
Interventions
OTHER
No Results Yet
NCT05105152 | RECRUITING | PHASE1
18 Participants

PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-11-29
Completion: 2028-02-28
Conditions
Acute Myeloid Leukemia Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia, in Relapse
Interventions
BIOLOGICAL
No Results Yet
NCT05103943 | ACTIVE_NOT_RECRUITING | NA
50 Participants

Amyloidosis TTR Flow Reserve Evaluation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-24
Completion: 2026-12-11
Conditions
Amyloid Cardiomyopathy
Interventions
OTHER
No Results Yet
NCT05091684 | TERMINATED | PHASE2
1 Participants

Administration of Fibrinogen Concentrate for Refractory Bleeding

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-10
Completion: 2023-05-25
Conditions
Hematological Patients Bleeding Platelet Refractoriness
Interventions
DRUG
No Results Yet
NCT05066503 | RECRUITING | NA
60 Participants

Nutritional Therapy for Delirium in Elderly Hospitalized Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-11-16
Completion: 2026-08-31
Conditions
Subacute Delirium
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT05048797 | ACTIVE_NOT_RECRUITING | PHASE3
454 Participants

A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-10-28
Completion: 2026-03-30
Conditions
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05029895 | COMPLETED
167 Participants

A Study to Evaluate Adverse Events and Change in Disease State of Oral Upadacitinib in Adolescent Participants Ages 12 to <18 Years Old Diagnosed With Atopic Dermatitis (AD)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-09-29
Completion: 2025-09-17
Conditions
Atopic Dermatitis
No Results Yet
NCT05026632 | RECRUITING | PHASE1/PHASE2
30 Participants

NPI-002 Intravitreal Implant for the Delay of Cataract Progression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-01-27
Completion: 2026-04-30
Conditions
Cataract
Interventions
DRUG
No Results Yet
NCT05005429 | COMPLETED | PHASE2
47 Participants

Study of the Efficacy and Safety of the Bintrafusp Alfa in Previously Treated Advanced Malignant Pleural Mesothelioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-09-20
Completion: 2024-02-01
Conditions
Mesothelioma; Lung
Interventions
DRUG
NCT05003986 | RECRUITING | PHASE2
67 Participants

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-08-12
Completion: 2027-03-12
Conditions
Focal Segmental Glomerulosclerosis Minimal Change Disease Immunoglobulin A Nephropathy IgA Vasculitis Alport Syndrome
Interventions
DRUG
No Results Yet
NCT04998864 | COMPLETED
53 Participants

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-08-25
Completion: 2023-07-27
Conditions
Glioma, Malignant Glioblastoma
Interventions
DEVICE
No Results Yet
NCT04997902 | COMPLETED | PHASE1/PHASE2
45 Participants

Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-12-07
Completion: 2025-07-30
Conditions
HNSCC
Interventions
DRUG
No Results Yet
NCT04990401 | COMPLETED | NA
65 Participants

Behavioral Activation Teletherapy to Increase Physical Activity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-08-31
Completion: 2025-05-30
Conditions
Depression Depressive Disorder Depressive Symptoms Depressive Episode
Interventions
BEHAVIORAL
No Results Yet
NCT04990167 | TERMINATED | PHASE2
11 Participants

Tiotropium vs. Inhaled Corticosteroids in Children With Nonatopic Asthma Pilot Study (TioNAAP)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-01-01
Completion: 2025-10-31
Conditions
Asthma in Children
Interventions
DRUG
No Results Yet
NCT04982575 | COMPLETED | PHASE2
92 Participants

Research Study to Look at How Well Cagrilintide Together With Semaglutide Works in People With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-08-02
Completion: 2022-07-07
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
NCT04975776 | ACTIVE_NOT_RECRUITING | NA
104 Participants

Sleep Restriction Therapy for Insomnia in Primary Health Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-01
Completion: 2027-08-30
Conditions
Insomnia
Interventions
BEHAVIORAL
No Results Yet
NCT04965766 | RECRUITING | PHASE2
139 Participants

Patritumab Deruxtecan (U3-1402) in Unresectable Locally Advanced or Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-05-11
Completion: 2027-04-11
Conditions
Advanced Breast Cancer Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT04960072 | RECRUITING | EARLY_PHASE1
50 Participants

A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-06-30
Completion: 2025-12-30
Conditions
Gastrointestinal Tumor
Interventions
BIOLOGICAL
No Results Yet
NCT04952766 | COMPLETED | PHASE4
196 Participants

Study Evaluating SARS-CoV-2 (COVID-19) Humoral Response After BNT162b2 Vaccine in Immunocompromised Adults Compared to Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-03-26
Completion: 2022-02-06
Conditions
Kidney Transplant Myeloma Cancer Hematologic Malignancy Multiple Sclerosis Hypergammaglobulinemia Malignant Tumor Hiv Diabetes Type 2
Interventions
BIOLOGICAL
No Results Yet
NCT04948333 | ACTIVE_NOT_RECRUITING | PHASE3
199 Participants

Asciminib Treatment Optimization in ≥ 3rd Line CML-CP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-10-13
Completion: 2024-03-12
Conditions
Chronic Myelogenous Leukemia
Interventions
DRUG
NCT04937647 | RECRUITING
1650 Participants

Evaluation of Neoplasia With Artificial Intelligence in Gastrointestinal Endoscopy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-06-16
Completion: 2026-06-03
Conditions
Gastrointestinal Neoplasms
Interventions
OTHER
No Results Yet
NCT04936035 | COMPLETED | PHASE2
394 Participants

A Study to Evaluate Efficacy and Safety of ALN-AGT01 in Patients With Mild To-Moderate Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-07-07
Completion: 2023-04-04
Conditions
Hypertension
Interventions
DRUG
NCT04933721 | ENROLLING_BY_INVITATION | PHASE3
139 Participants

Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-07-23
Completion: 2031-08-31
Conditions
Hereditary Angioedema HAE
Interventions
DRUG
No Results Yet
NCT04930822 | COMPLETED | NA
37 Participants

Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-01-08
Completion: 2024-06-12
Conditions
Stroke Neurologic Disorder Traumatic Brain Injury Acquired Brain Injury
Interventions
OTHER DEVICE
NCT04925752 | ACTIVE_NOT_RECRUITING | PHASE3
3292 Participants

Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-06-28
Completion: 2024-08-21
Conditions
Pre-Exposure Prophylaxis of HIV Infection
Interventions
DRUG
Previous
Sorted by latest updates
Next
Showing 40 trials per page