Clinical Trials

Showing trials with last updates posted in 2025.

NCT05217849 | ACTIVE_NOT_RECRUITING | NA
80 Participants

Multi-domain Online Therapeutic Investigation Of Neurocognition (MOTION)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-15
Completion: 2025-12-31
Conditions
Mild Cognitive Impairment Subjective Memory Decline
Interventions
BEHAVIORAL
No Results Yet
NCT05211895 | RECRUITING | PHASE3
860 Participants

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-18
Completion: 2028-07-12
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG OTHER
No Results Yet
NCT05197049 | ACTIVE_NOT_RECRUITING | PHASE3
350 Participants

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-01-19
Completion: 2023-07-04
Conditions
Crohn Disease
Interventions
DRUG
NCT05192434 | ACTIVE_NOT_RECRUITING | NA
219 Participants

Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-06-17
Completion: 2026-12-31
Conditions
HIV Infections Opioid Use Trauma, Psychological
Interventions
BEHAVIORAL
No Results Yet
NCT05182879 | RECRUITING
740 Participants

Evaluation of Frail Elderly in Ambulatory Primary Care

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2019-02-12
Completion: 2026-01-31
Conditions
Frailty
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05160701 | ACTIVE_NOT_RECRUITING | NA
300 Participants

Bringing Health Home

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-05-09
Completion: 2025-08-15
Conditions
Mental Disorders, Severe
Interventions
OTHER
No Results Yet
NCT05150210 | ACTIVE_NOT_RECRUITING | NA
32 Participants

SP Thoracic IDE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-07-20
Completion: 2023-06-16
Conditions
Primary Lung Cancer Benign Lung Disease Thymoma Myasthenia Gravis
Interventions
DEVICE
NCT05147792 | RECRUITING | NA
1600 Participants

The CONFORM Pivotal Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-05-26
Completion: 2028-06-30
Conditions
Atrial Fibrillation Stroke
Interventions
DEVICE
No Results Yet
NCT05137743 | ACTIVE_NOT_RECRUITING | NA
80 Participants

Pilot Test of Apnea and Insomnia Relief for Veterans With Gulf War Illness

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-15
Completion: 2025-12-31
Conditions
Gulf War Illness
Interventions
BEHAVIORAL
No Results Yet
NCT05133245 | ENROLLING_BY_INVITATION
50 Participants

PHACE - Prospective Genetic Investigation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-11-01
Completion: 2026-11-01
Conditions
PHACE Syndrome
Interventions
OTHER
No Results Yet
NCT05105152 | RECRUITING | PHASE1
18 Participants

PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-11-29
Completion: 2028-02-28
Conditions
Acute Myeloid Leukemia Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia, in Relapse
Interventions
BIOLOGICAL
No Results Yet
NCT05103943 | ACTIVE_NOT_RECRUITING | NA
50 Participants

Amyloidosis TTR Flow Reserve Evaluation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-24
Completion: 2026-12-11
Conditions
Amyloid Cardiomyopathy
Interventions
OTHER
No Results Yet
NCT05091684 | TERMINATED | PHASE2
1 Participants

Administration of Fibrinogen Concentrate for Refractory Bleeding

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-10
Completion: 2023-05-25
Conditions
Hematological Patients Bleeding Platelet Refractoriness
Interventions
DRUG
No Results Yet
NCT05066503 | RECRUITING | NA
60 Participants

Nutritional Therapy for Delirium in Elderly Hospitalized Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-11-16
Completion: 2026-08-31
Conditions
Subacute Delirium
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT05048797 | ACTIVE_NOT_RECRUITING | PHASE3
454 Participants

A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-10-28
Completion: 2026-03-30
Conditions
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05029895 | COMPLETED
167 Participants

A Study to Evaluate Adverse Events and Change in Disease State of Oral Upadacitinib in Adolescent Participants Ages 12 to <18 Years Old Diagnosed With Atopic Dermatitis (AD)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-09-29
Completion: 2025-09-17
Conditions
Atopic Dermatitis
No Results Yet
NCT05026632 | RECRUITING | PHASE1/PHASE2
30 Participants

NPI-002 Intravitreal Implant for the Delay of Cataract Progression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-01-27
Completion: 2026-04-30
Conditions
Cataract
Interventions
DRUG
No Results Yet
NCT05005429 | COMPLETED | PHASE2
47 Participants

Study of the Efficacy and Safety of the Bintrafusp Alfa in Previously Treated Advanced Malignant Pleural Mesothelioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-09-20
Completion: 2024-02-01
Conditions
Mesothelioma; Lung
Interventions
DRUG
NCT05003986 | RECRUITING | PHASE2
67 Participants

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-08-12
Completion: 2027-03-12
Conditions
Focal Segmental Glomerulosclerosis Minimal Change Disease Immunoglobulin A Nephropathy IgA Vasculitis Alport Syndrome
Interventions
DRUG
No Results Yet
NCT04998864 | COMPLETED
53 Participants

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-08-25
Completion: 2023-07-27
Conditions
Glioma, Malignant Glioblastoma
Interventions
DEVICE
No Results Yet
NCT04997902 | COMPLETED | PHASE1/PHASE2
45 Participants

Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-12-07
Completion: 2025-07-30
Conditions
HNSCC
Interventions
DRUG
No Results Yet
NCT04990401 | COMPLETED | NA
65 Participants

Behavioral Activation Teletherapy to Increase Physical Activity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-08-31
Completion: 2025-05-30
Conditions
Depression Depressive Disorder Depressive Symptoms Depressive Episode
Interventions
BEHAVIORAL
No Results Yet
NCT04990167 | TERMINATED | PHASE2
11 Participants

Tiotropium vs. Inhaled Corticosteroids in Children With Nonatopic Asthma Pilot Study (TioNAAP)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-01-01
Completion: 2025-10-31
Conditions
Asthma in Children
Interventions
DRUG
No Results Yet
NCT04982575 | COMPLETED | PHASE2
92 Participants

Research Study to Look at How Well Cagrilintide Together With Semaglutide Works in People With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-08-02
Completion: 2022-07-07
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
NCT04975776 | ACTIVE_NOT_RECRUITING | NA
104 Participants

Sleep Restriction Therapy for Insomnia in Primary Health Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-02-01
Completion: 2027-08-30
Conditions
Insomnia
Interventions
BEHAVIORAL
No Results Yet
NCT04965766 | RECRUITING | PHASE2
139 Participants

Patritumab Deruxtecan (U3-1402) in Unresectable Locally Advanced or Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-05-11
Completion: 2027-04-11
Conditions
Advanced Breast Cancer Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT04960072 | RECRUITING | EARLY_PHASE1
50 Participants

A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-06-30
Completion: 2025-12-30
Conditions
Gastrointestinal Tumor
Interventions
BIOLOGICAL
No Results Yet
NCT04952766 | COMPLETED | PHASE4
196 Participants

Study Evaluating SARS-CoV-2 (COVID-19) Humoral Response After BNT162b2 Vaccine in Immunocompromised Adults Compared to Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-03-26
Completion: 2022-02-06
Conditions
Kidney Transplant Myeloma Cancer Hematologic Malignancy Multiple Sclerosis Hypergammaglobulinemia Malignant Tumor Hiv Diabetes Type 2
Interventions
BIOLOGICAL
No Results Yet
NCT04948333 | ACTIVE_NOT_RECRUITING | PHASE3
199 Participants

Asciminib Treatment Optimization in ≥ 3rd Line CML-CP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-10-13
Completion: 2024-03-12
Conditions
Chronic Myelogenous Leukemia
Interventions
DRUG
NCT04937647 | RECRUITING
1650 Participants

Evaluation of Neoplasia With Artificial Intelligence in Gastrointestinal Endoscopy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-06-16
Completion: 2026-06-03
Conditions
Gastrointestinal Neoplasms
Interventions
OTHER
No Results Yet
NCT04936035 | COMPLETED | PHASE2
394 Participants

A Study to Evaluate Efficacy and Safety of ALN-AGT01 in Patients With Mild To-Moderate Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-07-07
Completion: 2023-04-04
Conditions
Hypertension
Interventions
DRUG
NCT04933721 | ENROLLING_BY_INVITATION | PHASE3
139 Participants

Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-07-23
Completion: 2031-08-31
Conditions
Hereditary Angioedema HAE
Interventions
DRUG
No Results Yet
NCT04930822 | COMPLETED | NA
37 Participants

Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-01-08
Completion: 2024-06-12
Conditions
Stroke Neurologic Disorder Traumatic Brain Injury Acquired Brain Injury
Interventions
OTHER DEVICE
NCT04925752 | ACTIVE_NOT_RECRUITING | PHASE3
3292 Participants

Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-06-28
Completion: 2024-08-21
Conditions
Pre-Exposure Prophylaxis of HIV Infection
Interventions
DRUG
NCT04914455 | COMPLETED
40 Participants

Transhepatic Echography for Fluid Responsiveness After Cardiovascular Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2020-12-08
Completion: 2021-06-04
Conditions
Inferior Vena Cava Abnormality Fluid Responsiveness Fluid Overload Venous Congestion Cardiovascular Surgery
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04911036 | RECRUITING
240 Participants

Study of the Effect of the Time of Diagnosis (Antenatal vs. Postnatal) on the Post-traumatic Reactions of Parents of Children Undergoing Oesophageal Atresia Surgery "

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-05-06
Completion: 2027-05-31
Conditions
Atresia, Esophageal
Interventions
OTHER
No Results Yet
NCT04902443 | RECRUITING | PHASE1
58 Participants

Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-12-10
Completion: 2026-12-01
Conditions
Viral Associated Malignancies Kaposi Sarcoma EBV/KSHV-associated Lymphomas
Interventions
DRUG
No Results Yet
NCT04895839 | RECRUITING | NA
2130 Participants

Predictors of Mental Health in Men With Prostate Cancer Undergoing a Patient Empowerment Program

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-09-29
Completion: 2027-09-29
Conditions
Prostate Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT04894253 | TERMINATED
7 Participants

Immune Response to SARS-CoV-2 Vaccination in Systemic Lupus

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-06-07
Completion: 2021-06-07
Conditions
Systemic Lupus
Interventions
BIOLOGICAL
No Results Yet
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