Clinical Trials
Showing trials with last updates posted in 2025.
180
Participants
P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-02-15
Completion:
2026-04-30
Conditions
Breast Cancer
Ovarian Cancer
Non Small Cell Lung Cancer
Colorectal Cancer
Pancreatic Cancer
Renal Cell Carcinoma
Nasopharyngeal Cancer
Head and Neck Squamous Cell Carcinoma
Gastric Cancer
Interventions
BIOLOGICAL
DRUG
No Results Yet
80
Participants
Multi-domain Online Therapeutic Investigation Of Neurocognition (MOTION)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-02-15
Completion:
2025-12-31
Conditions
Mild Cognitive Impairment
Subjective Memory Decline
Interventions
BEHAVIORAL
No Results Yet
860
Participants
A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-02-18
Completion:
2028-07-12
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
OTHER
No Results Yet
350
Participants
A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-01-19
Completion:
2023-07-04
Conditions
Crohn Disease
Interventions
DRUG
219
Participants
Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-06-17
Completion:
2026-12-31
Conditions
HIV Infections
Opioid Use
Trauma, Psychological
Interventions
BEHAVIORAL
No Results Yet
740
Participants
Evaluation of Frail Elderly in Ambulatory Primary Care
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2019-02-12
Completion:
2026-01-31
Conditions
Frailty
Interventions
DIAGNOSTIC_TEST
No Results Yet
300
Participants
Bringing Health Home
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-05-09
Completion:
2025-08-15
Conditions
Mental Disorders, Severe
Interventions
OTHER
No Results Yet
32
Participants
SP Thoracic IDE Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-07-20
Completion:
2023-06-16
Conditions
Primary Lung Cancer
Benign Lung Disease
Thymoma
Myasthenia Gravis
Interventions
DEVICE
1600
Participants
The CONFORM Pivotal Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-05-26
Completion:
2028-06-30
Conditions
Atrial Fibrillation
Stroke
Interventions
DEVICE
No Results Yet
80
Participants
Pilot Test of Apnea and Insomnia Relief for Veterans With Gulf War Illness
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-02-15
Completion:
2025-12-31
Conditions
Gulf War Illness
Interventions
BEHAVIORAL
No Results Yet
50
Participants
PHACE - Prospective Genetic Investigation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2021-11-01
Completion:
2026-11-01
Conditions
PHACE Syndrome
Interventions
OTHER
No Results Yet
18
Participants
PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-11-29
Completion:
2028-02-28
Conditions
Acute Myeloid Leukemia
Acute Myeloid Leukemia Refractory
Acute Myeloid Leukemia, in Relapse
Interventions
BIOLOGICAL
No Results Yet
50
Participants
Amyloidosis TTR Flow Reserve Evaluation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-02-24
Completion:
2026-12-11
Conditions
Amyloid Cardiomyopathy
Interventions
OTHER
No Results Yet
1
Participants
Administration of Fibrinogen Concentrate for Refractory Bleeding
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-02-10
Completion:
2023-05-25
Conditions
Hematological Patients
Bleeding
Platelet Refractoriness
Interventions
DRUG
No Results Yet
454
Participants
A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-10-28
Completion:
2026-03-30
Conditions
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
167
Participants
A Study to Evaluate Adverse Events and Change in Disease State of Oral Upadacitinib in Adolescent Participants Ages 12 to <18 Years Old Diagnosed With Atopic Dermatitis (AD)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2021-09-29
Completion:
2025-09-17
Conditions
Atopic Dermatitis
No Results Yet
30
Participants
NPI-002 Intravitreal Implant for the Delay of Cataract Progression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-01-27
Completion:
2026-04-30
Conditions
Cataract
Interventions
DRUG
No Results Yet
47
Participants
Study of the Efficacy and Safety of the Bintrafusp Alfa in Previously Treated Advanced Malignant Pleural Mesothelioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-09-20
Completion:
2024-02-01
Conditions
Mesothelioma; Lung
Interventions
DRUG
67
Participants
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-08-12
Completion:
2027-03-12
Conditions
Focal Segmental Glomerulosclerosis
Minimal Change Disease
Immunoglobulin A Nephropathy
IgA Vasculitis
Alport Syndrome
Interventions
DRUG
No Results Yet
53
Participants
Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2021-08-25
Completion:
2023-07-27
Conditions
Glioma, Malignant
Glioblastoma
Interventions
DEVICE
No Results Yet
45
Participants
Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-12-07
Completion:
2025-07-30
Conditions
HNSCC
Interventions
DRUG
No Results Yet
65
Participants
Behavioral Activation Teletherapy to Increase Physical Activity
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-08-31
Completion:
2025-05-30
Conditions
Depression
Depressive Disorder
Depressive Symptoms
Depressive Episode
Interventions
BEHAVIORAL
No Results Yet
11
Participants
Tiotropium vs. Inhaled Corticosteroids in Children With Nonatopic Asthma Pilot Study (TioNAAP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-01-01
Completion:
2025-10-31
Conditions
Asthma in Children
Interventions
DRUG
No Results Yet
776
Participants
A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-11-17
Completion:
2023-07-10
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
92
Participants
Research Study to Look at How Well Cagrilintide Together With Semaglutide Works in People With Type 2 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-08-02
Completion:
2022-07-07
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
104
Participants
Sleep Restriction Therapy for Insomnia in Primary Health Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2022-02-01
Completion:
2027-08-30
Conditions
Insomnia
Interventions
BEHAVIORAL
No Results Yet
139
Participants
Patritumab Deruxtecan (U3-1402) in Unresectable Locally Advanced or Metastatic Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-05-11
Completion:
2027-04-11
Conditions
Advanced Breast Cancer
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
50
Participants
A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-06-30
Completion:
2025-12-30
Conditions
Gastrointestinal Tumor
Interventions
BIOLOGICAL
No Results Yet
196
Participants
Study Evaluating SARS-CoV-2 (COVID-19) Humoral Response After BNT162b2 Vaccine in Immunocompromised Adults Compared to Healthy Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-03-26
Completion:
2022-02-06
Conditions
Kidney Transplant
Myeloma
Cancer
Hematologic Malignancy
Multiple Sclerosis
Hypergammaglobulinemia
Malignant Tumor
Hiv
Diabetes Type 2
Interventions
BIOLOGICAL
No Results Yet
199
Participants
Asciminib Treatment Optimization in ≥ 3rd Line CML-CP
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-10-13
Completion:
2024-03-12
Conditions
Chronic Myelogenous Leukemia
Interventions
DRUG
1650
Participants
Evaluation of Neoplasia With Artificial Intelligence in Gastrointestinal Endoscopy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2021-06-16
Completion:
2026-06-03
Conditions
Gastrointestinal Neoplasms
Interventions
OTHER
No Results Yet
394
Participants
A Study to Evaluate Efficacy and Safety of ALN-AGT01 in Patients With Mild To-Moderate Hypertension
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-07-07
Completion:
2023-04-04
Conditions
Hypertension
Interventions
DRUG
139
Participants
Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-07-23
Completion:
2031-08-31
Conditions
Hereditary Angioedema
HAE
Interventions
DRUG
No Results Yet
37
Participants
Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-01-08
Completion:
2024-06-12
Conditions
Stroke
Neurologic Disorder
Traumatic Brain Injury
Acquired Brain Injury
Interventions
OTHER
DEVICE
3292
Participants
Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-06-28
Completion:
2024-08-21
Conditions
Pre-Exposure Prophylaxis of HIV Infection
Interventions
DRUG
40
Participants
Transhepatic Echography for Fluid Responsiveness After Cardiovascular Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2020-12-08
Completion:
2021-06-04
Conditions
Inferior Vena Cava Abnormality
Fluid Responsiveness
Fluid Overload
Venous Congestion
Cardiovascular Surgery
Interventions
DIAGNOSTIC_TEST
No Results Yet
240
Participants
Study of the Effect of the Time of Diagnosis (Antenatal vs. Postnatal) on the Post-traumatic Reactions of Parents of Children Undergoing Oesophageal Atresia Surgery "
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2021-05-06
Completion:
2027-05-31
Conditions
Atresia, Esophageal
Interventions
OTHER
No Results Yet
58
Participants
Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-12-10
Completion:
2026-12-01
Conditions
Viral Associated Malignancies
Kaposi Sarcoma
EBV/KSHV-associated Lymphomas
Interventions
DRUG
No Results Yet
2130
Participants
Predictors of Mental Health in Men With Prostate Cancer Undergoing a Patient Empowerment Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-09-29
Completion:
2027-09-29
Conditions
Prostate Cancer
Interventions
BEHAVIORAL
No Results Yet
7
Participants
Immune Response to SARS-CoV-2 Vaccination in Systemic Lupus
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2021-06-07
Completion:
2021-06-07
Conditions
Systemic Lupus
Interventions
BIOLOGICAL
No Results Yet
Showing 40 trials per page