Clinical Trials
Showing trials with last updates posted in 2025.
188
Participants
Implementation and Evaluation of a Before School Physical Activity Program in Revere, MA
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-02-16
Completion:
2018-12-30
Conditions
Overweight and Obesity
Physical Activity
Quality of Life
Fitness
Executive Function
Interventions
OTHER
400
Participants
Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2020-04-16
Completion:
2026-12-31
Conditions
Metastatic Colon Cancer
Stage III Colon Cancer
Interventions
DRUG
OTHER
No Results Yet
338
Participants
A Registry for Patients With Multifocal Ground Glass Opacities (GGOs)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2019-01-09
Completion:
2026-01-31
Conditions
Multiple Ground Glass Opacities (GGOs)
No Results Yet
10
Participants
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-11-15
Completion:
2028-12-30
Conditions
BCR-JAK2 Fusion Protein Expression
Blasts 20 Percent or Less of Peripheral Blood White Cells
Blasts More Than 5 Percent of Bone Marrow Nucleated Cells
Blasts More Than 5 Percent of Peripheral Blood White Cells
Blasts Under 20 Percent of Bone Marrow Nucleated Cells
Chronic Eosinophilic Leukemia, Not Otherwise Specified
Eosinophilia
Hepatomegaly
Hypereosinophilic Syndrome
JAK2 Gene Mutation
Splenomegaly
TEL-JAK2 Fusion Protein Expression
Interventions
DRUG
No Results Yet
15
Participants
Impact of a Physical Activity Program on Bone Mineral Density in Children and Adolescents With Chronic Inflammatory Bowel Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2020-03-02
Completion:
2021-12-08
Conditions
Crohn's Enteritis
Crohn Disease
Ulcerative Colitis
Chronic; Colitis (Noninfective)
Interventions
OTHER
No Results Yet
275
Participants
De-escalation - Antifungal Treatment Immunocompromised Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2019-01-28
Completion:
2023-11-07
Conditions
Invasive Fungal Disease
Critical Illness
No Results Yet
266
Participants
Early Stop(Ruling) of the Antibiotic Treatment During Pneumopathies d' Inhalation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-09-20
Completion:
2024-02-22
Conditions
Aspiration Pneumonia
Interventions
PROCEDURE
No Results Yet
136
Participants
Repeat Quadratus Lumborum Block to Reduce Opioid Need in Patients After Pancreatic Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-02-28
Completion:
2025-07-31
Conditions
Pancreatic Carcinoma
Interventions
OTHER
DRUG
90
Participants
Premedication by Clonidine Intranasal in Pediatric Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-03-26
Completion:
2021-11-24
Conditions
Child Preschool
Interventions
DRUG
OTHER
No Results Yet
88
Participants
Hypnosis Mask: a New Approach to Management of Pain in Medical Imaging
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-05-07
Completion:
2021-10-26
Conditions
Prostatic Diseases
Interventions
PROCEDURE
DEVICE
No Results Yet
1014
Participants
Post-Authorization Long-Term Safety Study of LUTATHERA
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-11-28
Completion:
2027-09-30
Conditions
Neuroendocrine Tumors
Interventions
DRUG
No Results Yet
100
Participants
Laser Therapy for Treatment of Urogenital Symptoms in Women
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-10-08
Completion:
2022-12-15
Conditions
Genitourinary System; Disorder, Female
Burning Vagina
Dyspareunia
Irritation; Vagina
Menopause Related Conditions
Urinary Incontinence
Urinary Bladder, Overactive
Urinary Tract Infections
Stress Urinary Incontinence
Interventions
DEVICE
51
Participants
Ribociclib and Letrozole Treatment in Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-05-20
Completion:
2024-12-23
Conditions
Low Grade Serous Carcinoma
Interventions
DRUG
386
Participants
Life Enhancing Activities for Family Caregivers (LEAF 2.0)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2020-07-13
Completion:
2024-09-04
Conditions
Caregivers
Interventions
BEHAVIORAL
OTHER
20
Participants
A Study to Evaluate Temporary Blood Brain Barrier Disruption in Patients With Parkinson's Disease Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-11-26
Completion:
2021-10-31
Conditions
Parkinsons Disease With Dementia
Interventions
DEVICE
No Results Yet
34
Participants
Study of CVM-1118 for Patients With Advanced Neuroendocrine Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-12-15
Completion:
2024-09-30
Conditions
Neuroendocrine Tumors
Pancreatic Neuroendocrine Tumor
Gastro-enteropancreatic Neuroendocrine Tumor
Lung Neuroendocrine Neoplasm
Neuroendocrine Carcinoma
Interventions
DRUG
No Results Yet
1353
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-09-05
Completion:
2023-11-14
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Chronic Plaque Psoriasis
Interventions
DRUG
1533
Participants
A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-08-09
Completion:
2021-02-16
Conditions
Atopic Dermatitis
Interventions
DRUG
106
Participants
Assessment of Individual Follow-up by Coaching Program for Type 1 Diabetes Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-09-29
Completion:
2021-06-25
Conditions
Diabetes type1
Interventions
OTHER
No Results Yet
71
Participants
Profibrosing Role of B Lymphocytes in Patients With Systemic Sclerosis.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-10-29
Completion:
2023-02-14
Conditions
Scleroderma, Systemic
Interventions
PROCEDURE
OTHER
No Results Yet
743
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-06-13
Completion:
2019-09-12
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Chronic Plaque Psoriasis
Interventions
DRUG
OTHER
34
Participants
Exercise Training and Endothelial Function in Type 1 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-11-12
Completion:
2026-01-31
Conditions
Type1diabetes
Interventions
BEHAVIORAL
No Results Yet
1063
Participants
A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-07-18
Completion:
2026-07-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
140
Participants
Evaluation of Cognitive Function in a Suicidal Crisis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2016-09-20
Completion:
2024-03-25
Conditions
Suicide
No Results Yet
1000
Participants
Determinants of the Long-Term Success of Bariatric Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-07-31
Completion:
2026-01-31
Conditions
Morbid Obesity
Bariatric Surgery Candidate
No Results Yet
29
Participants
Study of Dysarthria, and the Appearance of Non-dopaminergic Signs in Idiopathic PARKinson's Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2017-05-11
Completion:
2018-11-12
Conditions
Parkinson Disease
No Results Yet
200
Participants
Ablative Therapy in the Management of Prostate Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-01-02
Completion:
2032-03-02
Conditions
Prostate Cancer
Interventions
DEVICE
No Results Yet
52
Participants
INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-05-31
Completion:
2026-12-31
Conditions
Glioblastoma
Interventions
BIOLOGICAL
RADIATION
DRUG
No Results Yet
58
Participants
Heritability of Polycystic Ovary Syndrome: Role of Antimullerian Hormone, Steroids and Leptin
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-04-20
Completion:
2022-06-02
Conditions
Polycystic Ovary Syndrome
Interventions
BIOLOGICAL
GENETIC
No Results Yet
125
Participants
A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-04-05
Completion:
2022-09-30
Conditions
Urothelial Carcinoma
Interventions
DRUG
36
Participants
A Study to Evaluate the Safety and Efficacy of ExAblate Subthalomotomy for the Treatment of Parkinson's Disease Motor Features
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-02-27
Completion:
2020-06-15
Conditions
Parkinson Disease
Interventions
DEVICE
No Results Yet
120
Participants
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-07-11
Completion:
2023-07-19
Conditions
Psoriasis
Interventions
DRUG
8
Participants
Dynamic of Immunocompetent Populations in Patients Treated With Extracorporeal Photopheresis in Chronic Graft Versus Host Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-05-07
Completion:
2019-12-02
Conditions
Graft Versus Host Disease
Extracorporeal Photopheresis
Interventions
DIAGNOSTIC_TEST
No Results Yet
136
Participants
A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-03-02
Completion:
2021-08-31
Conditions
Prostatic Neoplasms, Castration-Resistant
Interventions
DRUG
478
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-01-26
Completion:
2019-02-07
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Plaque Psoriasis
Interventions
DRUG
OTHER
435
Participants
A Study With a Initial Treatment Period Followed by a Randomized-withdrawal Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-02-05
Completion:
2018-12-28
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Chronic Plaque Psoriasis
Psoriatic Arthritis
Interventions
DRUG
OTHER
43
Participants
Oleclumab (MEDI9447) Epidermal Growth Factor Receptor Mutant (EGFRm) Non-small Cell Lung Cancer (NSCLC) Novel Combination Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-05-08
Completion:
2021-05-24
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL
DRUG
567
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Placebo and an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-12-06
Completion:
2019-01-08
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Chronic Plaque Psoriasis
Psoriatic Arthritis
Interventions
DRUG
OTHER
40
Participants
Development of an Epileptic Seizure Detection Algorithm by Continuous Analysis of the Electrocardiogram
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2017-12-13
Completion:
2019-12-12
Conditions
Seizures
Epilepsy
Electrocardiography
No Results Yet
13
Participants
Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-01-18
Completion:
2023-07-21
Conditions
Angiosarcoma
Epithelioid Hemangioendothelioma
Interventions
DRUG
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