Clinical Trials
Showing trials with last updates posted in 2025.
396
Participants
Impact of Long Alimentary Limb or Long Biliary Limb Roux-en-Y Gastric Bypass on Type 2 Diabetes Remission in Severely Obese Patients.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-06-16
Completion:
2026-06-30
Conditions
Diabetes Mellitus Type 2 in Obese
Interventions
PROCEDURE
No Results Yet
70
Participants
Role of Eosinophil in Fibrogenesis of Systemic Sclerosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-10-03
Completion:
2022-04-05
Conditions
Systemic Sclerosis
Systemic Scleroderma
Interventions
DIAGNOSTIC_TEST
No Results Yet
22
Participants
Study of Dacomitinib and Osimertinib for Patients With Advanced EGFR Mutant Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-01-17
Completion:
2025-12-15
Conditions
Metastatic Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
188
Participants
Implementation and Evaluation of a Before School Physical Activity Program in Revere, MA
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-02-16
Completion:
2018-12-30
Conditions
Overweight and Obesity
Physical Activity
Quality of Life
Fitness
Executive Function
Interventions
OTHER
400
Participants
Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2020-04-16
Completion:
2026-12-31
Conditions
Metastatic Colon Cancer
Stage III Colon Cancer
Interventions
DRUG
OTHER
No Results Yet
338
Participants
A Registry for Patients With Multifocal Ground Glass Opacities (GGOs)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2019-01-09
Completion:
2026-01-31
Conditions
Multiple Ground Glass Opacities (GGOs)
No Results Yet
10
Participants
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-11-15
Completion:
2028-12-30
Conditions
BCR-JAK2 Fusion Protein Expression
Blasts 20 Percent or Less of Peripheral Blood White Cells
Blasts More Than 5 Percent of Bone Marrow Nucleated Cells
Blasts More Than 5 Percent of Peripheral Blood White Cells
Blasts Under 20 Percent of Bone Marrow Nucleated Cells
Chronic Eosinophilic Leukemia, Not Otherwise Specified
Eosinophilia
Hepatomegaly
Hypereosinophilic Syndrome
JAK2 Gene Mutation
Splenomegaly
TEL-JAK2 Fusion Protein Expression
Interventions
DRUG
No Results Yet
15
Participants
Impact of a Physical Activity Program on Bone Mineral Density in Children and Adolescents With Chronic Inflammatory Bowel Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2020-03-02
Completion:
2021-12-08
Conditions
Crohn's Enteritis
Crohn Disease
Ulcerative Colitis
Chronic; Colitis (Noninfective)
Interventions
OTHER
No Results Yet
275
Participants
De-escalation - Antifungal Treatment Immunocompromised Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2019-01-28
Completion:
2023-11-07
Conditions
Invasive Fungal Disease
Critical Illness
No Results Yet
266
Participants
Early Stop(Ruling) of the Antibiotic Treatment During Pneumopathies d' Inhalation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-09-20
Completion:
2024-02-22
Conditions
Aspiration Pneumonia
Interventions
PROCEDURE
No Results Yet
136
Participants
Repeat Quadratus Lumborum Block to Reduce Opioid Need in Patients After Pancreatic Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-02-28
Completion:
2025-07-31
Conditions
Pancreatic Carcinoma
Interventions
OTHER
DRUG
90
Participants
Premedication by Clonidine Intranasal in Pediatric Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-03-26
Completion:
2021-11-24
Conditions
Child Preschool
Interventions
DRUG
OTHER
No Results Yet
88
Participants
Hypnosis Mask: a New Approach to Management of Pain in Medical Imaging
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-05-07
Completion:
2021-10-26
Conditions
Prostatic Diseases
Interventions
PROCEDURE
DEVICE
No Results Yet
1014
Participants
Post-Authorization Long-Term Safety Study of LUTATHERA
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-11-28
Completion:
2027-09-30
Conditions
Neuroendocrine Tumors
Interventions
DRUG
No Results Yet
100
Participants
Laser Therapy for Treatment of Urogenital Symptoms in Women
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-10-08
Completion:
2022-12-15
Conditions
Genitourinary System; Disorder, Female
Burning Vagina
Dyspareunia
Irritation; Vagina
Menopause Related Conditions
Urinary Incontinence
Urinary Bladder, Overactive
Urinary Tract Infections
Stress Urinary Incontinence
Interventions
DEVICE
51
Participants
Ribociclib and Letrozole Treatment in Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-05-20
Completion:
2024-12-23
Conditions
Low Grade Serous Carcinoma
Interventions
DRUG
386
Participants
Life Enhancing Activities for Family Caregivers (LEAF 2.0)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2020-07-13
Completion:
2024-09-04
Conditions
Caregivers
Interventions
BEHAVIORAL
OTHER
20
Participants
A Study to Evaluate Temporary Blood Brain Barrier Disruption in Patients With Parkinson's Disease Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-11-26
Completion:
2021-10-31
Conditions
Parkinsons Disease With Dementia
Interventions
DEVICE
No Results Yet
34
Participants
Study of CVM-1118 for Patients With Advanced Neuroendocrine Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-12-15
Completion:
2024-09-30
Conditions
Neuroendocrine Tumors
Pancreatic Neuroendocrine Tumor
Gastro-enteropancreatic Neuroendocrine Tumor
Lung Neuroendocrine Neoplasm
Neuroendocrine Carcinoma
Interventions
DRUG
No Results Yet
1353
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-09-05
Completion:
2023-11-14
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Chronic Plaque Psoriasis
Interventions
DRUG
1533
Participants
A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-08-09
Completion:
2021-02-16
Conditions
Atopic Dermatitis
Interventions
DRUG
106
Participants
Assessment of Individual Follow-up by Coaching Program for Type 1 Diabetes Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-09-29
Completion:
2021-06-25
Conditions
Diabetes type1
Interventions
OTHER
No Results Yet
71
Participants
Profibrosing Role of B Lymphocytes in Patients With Systemic Sclerosis.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-10-29
Completion:
2023-02-14
Conditions
Scleroderma, Systemic
Interventions
PROCEDURE
OTHER
No Results Yet
743
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-06-13
Completion:
2019-09-12
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Chronic Plaque Psoriasis
Interventions
DRUG
OTHER
34
Participants
Exercise Training and Endothelial Function in Type 1 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-11-12
Completion:
2026-01-31
Conditions
Type1diabetes
Interventions
BEHAVIORAL
No Results Yet
1063
Participants
A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-07-18
Completion:
2026-07-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
140
Participants
Evaluation of Cognitive Function in a Suicidal Crisis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2016-09-20
Completion:
2024-03-25
Conditions
Suicide
No Results Yet
1000
Participants
Determinants of the Long-Term Success of Bariatric Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-07-31
Completion:
2026-01-31
Conditions
Morbid Obesity
Bariatric Surgery Candidate
No Results Yet
29
Participants
Study of Dysarthria, and the Appearance of Non-dopaminergic Signs in Idiopathic PARKinson's Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2017-05-11
Completion:
2018-11-12
Conditions
Parkinson Disease
No Results Yet
200
Participants
Ablative Therapy in the Management of Prostate Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-01-02
Completion:
2032-03-02
Conditions
Prostate Cancer
Interventions
DEVICE
No Results Yet
52
Participants
INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-05-31
Completion:
2026-12-31
Conditions
Glioblastoma
Interventions
BIOLOGICAL
RADIATION
DRUG
No Results Yet
58
Participants
Heritability of Polycystic Ovary Syndrome: Role of Antimullerian Hormone, Steroids and Leptin
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-04-20
Completion:
2022-06-02
Conditions
Polycystic Ovary Syndrome
Interventions
BIOLOGICAL
GENETIC
No Results Yet
125
Participants
A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-04-05
Completion:
2022-09-30
Conditions
Urothelial Carcinoma
Interventions
DRUG
36
Participants
A Study to Evaluate the Safety and Efficacy of ExAblate Subthalomotomy for the Treatment of Parkinson's Disease Motor Features
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-02-27
Completion:
2020-06-15
Conditions
Parkinson Disease
Interventions
DEVICE
No Results Yet
120
Participants
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-07-11
Completion:
2023-07-19
Conditions
Psoriasis
Interventions
DRUG
8
Participants
Dynamic of Immunocompetent Populations in Patients Treated With Extracorporeal Photopheresis in Chronic Graft Versus Host Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-05-07
Completion:
2019-12-02
Conditions
Graft Versus Host Disease
Extracorporeal Photopheresis
Interventions
DIAGNOSTIC_TEST
No Results Yet
136
Participants
A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-03-02
Completion:
2021-08-31
Conditions
Prostatic Neoplasms, Castration-Resistant
Interventions
DRUG
478
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-01-26
Completion:
2019-02-07
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Plaque Psoriasis
Interventions
DRUG
OTHER
435
Participants
A Study With a Initial Treatment Period Followed by a Randomized-withdrawal Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-02-05
Completion:
2018-12-28
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Chronic Plaque Psoriasis
Psoriatic Arthritis
Interventions
DRUG
OTHER
43
Participants
Oleclumab (MEDI9447) Epidermal Growth Factor Receptor Mutant (EGFRm) Non-small Cell Lung Cancer (NSCLC) Novel Combination Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-05-08
Completion:
2021-05-24
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL
DRUG
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