Clinical Trials

Showing trials with last updates posted in 2025.

NCT06919666 | RECRUITING | PHASE1/PHASE2
29 Participants

NT219 Combined With Standard of Care Biologic Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-12
Completion: 2030-02-28
Conditions
Head and Neck Cancer Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT06917690 | RECRUITING | PHASE3
6 Participants

A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis Bullosa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-18
Completion: 2026-03-31
Conditions
Epidermolysis Bullosa Junctional Epidermolysis Bullosa Epidermolysis Bullosa, Dystrophic Epidermolysis Bullosa, Junctional Skin Abnormalities Connective Tissue Disease Collagen Diseases Skin Diseases Genetic Diseases, Inborn Congenital Abnormalities
Interventions
DRUG
No Results Yet
NCT06914609 | RECRUITING | PHASE3
158 Participants

REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-10
Completion: 2027-08-31
Conditions
Angelman Syndrome
Interventions
DRUG
No Results Yet
NCT06910540 | RECRUITING | NA
144 Participants

ACU-TENS on Pain and Stress Reduction Before and During TUGOR

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-09-01
Completion: 2027-12-31
Conditions
Oocyte Retrieival and Post Operative Pain Control Acupuncture
Interventions
OTHER
No Results Yet
NCT06909669 | NOT_YET_RECRUITING | NA
184 Participants

Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-02-28
Completion: 2028-06-30
Conditions
Depression - Major Depressive Disorder Generalized Anxiety Disorder Generalized Anxiety Anxiety Somatoform Disorders Somatic Symptom Disorder (DSM-5) Somatization Emotional Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06907537 | COMPLETED | NA
44 Participants

A Study to Verify the Sleep-improving Effects of the Test Food Consumption

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-03
Completion: 2025-12-15
Conditions
Healthy Japanese
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06907147 | RECRUITING | NA
175 Participants

SPYRAL GEMINI Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-01
Completion: 2029-12-22
Conditions
Cardiovascular Diseases Chronic Kidney Diseases Diabetes Mellitus Hypertension Vascular Diseases
Interventions
DEVICE
No Results Yet
NCT06906939 | NOT_YET_RECRUITING | EARLY_PHASE1
30 Participants

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-02-01
Completion: 2029-06-30
Conditions
Knee Osteoarthritis Depression
Interventions
DEVICE
No Results Yet
NCT06906926 | RECRUITING | NA
80 Participants

Harmony TPV EMEA PMS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-07-30
Completion: 2027-07-31
Conditions
Severe Pulmonary Valve Regurgitation
Interventions
RADIATION
No Results Yet
NCT06894979 | RECRUITING | PHASE1
54 Participants

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-02-01
Completion: 2028-03-31
Conditions
Childhood Astrocytoma Childhood Diffuse Intrinsic Pontine Glioma Childhood Diffuse Midline Glioma Childhood Glioblastoma Childhood Malignant Glioma
Interventions
DRUG PROCEDURE RADIATION OTHER
No Results Yet
NCT06892522 | RECRUITING | PHASE1/PHASE2
440 Participants
NCT06892145 | RECRUITING | PHASE1
12 Participants

Clinical Trial of CD19 Targeted CAR-T Cell in Refractory Adult SLE

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-12
Completion: 2026-05-04
Conditions
Systemic Lupus Erythematosus (SLE) Refractory
Interventions
BIOLOGICAL
No Results Yet
NCT06888011 | RECRUITING | NA
1024 Participants

iAmHealthy Clinical Practice Guideline (CPG)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-09-06
Completion: 2028-11-30
Conditions
Pediatric Obesity Rural Health Clinical Practice Guideline
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06883448 | RECRUITING | NA
220 Participants

Implementation of Home Monitoring in Patients With Pulmonary Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-02
Completion: 2026-09-01
Conditions
Pulmonary Fibrosis Interstitial Lung Disease (ILD)
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT06874790 | RECRUITING | NA
700 Participants

RCT for Latina Mental Health Using Web-Based Apps

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-07-09
Completion: 2028-11-30
Conditions
Mental Health Anxiety Depression Well-Being, Psychological
Interventions
BEHAVIORAL
No Results Yet
NCT06868368 | COMPLETED | NA
53 Participants

Perceptions of Vaping Products

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-03
Completion: 2025-11-04
Conditions
Abuse Tobacco Exposure
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT06868290 | RECRUITING | PHASE2
126 Participants

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-13
Completion: 2029-06-07
Conditions
ANCA Associated Vasculitis (AAV)
Interventions
BIOLOGICAL OTHER DRUG
No Results Yet
NCT06868212 | RECRUITING | PHASE3
400 Participants

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-07-11
Completion: 2027-02-22
Conditions
Chronic Spontaneous Urticaria (CSU)
Interventions
DRUG
No Results Yet
NCT06866418 | RECRUITING
600 Participants

Phagenyx® Registry Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-09-15
Completion: 2035-09-30
Conditions
Dysphagia
Interventions
DEVICE
No Results Yet
NCT06862193 | RECRUITING | NA
440 Participants

Effectiveness of Digital Intervention (HM4MH-app) on Perinatal Psychological Wellbeing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-10
Completion: 2027-12-31
Conditions
Perinatal Mental Health Mobile Application Behavior
Interventions
BEHAVIORAL
No Results Yet
NCT06844669 | RECRUITING | PHASE2
40 Participants

HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-16
Completion: 2026-02-28
Conditions
HER2-positive Breast Cancer HER2+ Breast Cancer
Interventions
DRUG
No Results Yet
NCT06842381 | ACTIVE_NOT_RECRUITING | NA
100 Participants

Electrotherapy Combined With Neck Exercises for Non-Specific Neck Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-01
Completion: 2025-12-30
Conditions
Chronic Pain
Interventions
OTHER
No Results Yet
NCT06842186 | RECRUITING | PHASE1
136 Participants

A Phase 1 Study of WVE-007 in Adults Living With Overweight or Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-01-31
Completion: 2026-10-31
Conditions
Obesity and Overweight
Interventions
DRUG
No Results Yet
NCT06838364 | RECRUITING | NA
249 Participants

Comparison of the Effectiveness of Ultrasound-guided Techniques and Infrared Illumination, Compared With the Standard Approach to Peripheral Venous Line Placement in People With Difficult Venous Access

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-08
Completion: 2026-04-08
Conditions
Peripheral Venous Catheterization
Interventions
OTHER
No Results Yet
NCT06835595 | RECRUITING | NA
52 Participants

TMS-related Measures as Biomarker of Cognitive Impairment in PD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-09-10
Completion: 2029-01-01
Conditions
Parkinson Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06828679 | RECRUITING | NA
400 Participants

Using AI Systems to Optimize the Clinical Outcome of Stroke Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-07-01
Completion: 2027-12-31
Conditions
Acute Stroke Intervention Acute Stroke Acute Ischemic Stroke
Interventions
OTHER DEVICE
No Results Yet
NCT06827262 | RECRUITING
1500 Participants

Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-26
Completion: 2034-07-31
Conditions
Chronic Low-back Pain Vertebrogenic Pain Syndrome
Interventions
DEVICE
No Results Yet
NCT06822907 | NOT_YET_RECRUITING | PHASE4
1052 Participants

Immunogenicity and Safety PCV-20 of the Vaccine Administered During an Acute Febrile Illness in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-01-31
Completion: 2028-10-01
Conditions
Acute Febrile Illness Pneumococcal Infections
Interventions
BIOLOGICAL
No Results Yet
NCT06821087 | ENROLLING_BY_INVITATION | PHASE2
20 Participants

Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-28
Completion: 2026-03-31
Conditions
Long COVID
Interventions
DRUG
No Results Yet
NCT06816979 | NOT_YET_RECRUITING | NA
40 Participants

Lumbar Punctures for the Detection of ctDNA in the Cerebrospinal Fluid of Patients With Stage III and IV Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-01-15
Completion: 2026-10-31
Conditions
Lung Non-Small Cell Carcinoma Stage III Lung Cancer AJCC v8 Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE DEVICE
No Results Yet
NCT06811363 | NOT_YET_RECRUITING
25 Participants

Contribution of Bone to Urine Citrate

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2026-01-31
Completion: 2026-03-31
Conditions
Osteoporosis
Interventions
OTHER DRUG
No Results Yet
NCT06808776 | RECRUITING | NA
200 Participants

Stories to Prevent (StoP) HPV Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-11-17
Completion: 2026-10-01
Conditions
Human Papillomavirus Vaccination Emotions
Interventions
OTHER
No Results Yet
NCT06805305 | RECRUITING | PHASE2
180 Participants

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-17
Completion: 2030-03-31
Conditions
Glioblastoma (GBM)
Interventions
BIOLOGICAL PROCEDURE DRUG RADIATION
No Results Yet
NCT06804824 | RECRUITING | PHASE1
220 Participants

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-159642 in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-02-25
Completion: 2027-08-01
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06804161 | RECRUITING | PHASE3
3000 Participants

SGLT2 Inhibition for Cardiovascular Endpoint Reduction in Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-12-10
Completion: 2032-05-30
Conditions
Atrial Hypertension
Interventions
DRUG
No Results Yet
NCT06799546 | COMPLETED | PHASE3
73 Participants

A Phase III Study to Evaluate the Efficacy and Safety of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Are Naive to Complement Inhibitor Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-02-13
Completion: 2025-11-05
Conditions
PNH
Interventions
DRUG
No Results Yet
NCT06796062 | RECRUITING | PHASE2
480 Participants

Psilocybin for Opioid Use Disorder (OUD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-12-17
Completion: 2029-02-28
Conditions
Opioid Use Disorder
Interventions
DRUG
No Results Yet
NCT06793852 | COMPLETED
78 Participants

Shoulder Pain and Its Effects on Joint Position, Strength, Tactical Sensory and Posture in Hemiplegia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-02-25
Completion: 2025-06-20
Conditions
Hemiplegic Shoulder Pain
No Results Yet
NCT06792344 | RECRUITING | PHASE1
12 Participants

Clinical Study of CD19 CAR-T in the Treatment of Refractory Systemic Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-12-15
Completion: 2027-12-30
Conditions
Systemic Sclerosis (SSc)
Interventions
OTHER DRUG
No Results Yet
NCT06790121 | ACTIVE_NOT_RECRUITING | PHASE2
150 Participants

A Study to Investigate the Efficacy and Safety of Subcutaneous Lunsekimig (SAR443765) Compared With Placebo in Adult Participants With Moderate-to-severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-02-03
Completion: 2025-12-31
Conditions
Dermatitis Atopic
Interventions
DRUG
No Results Yet
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