Clinical Trials
Showing trials with last updates posted in 2025.
392
Participants
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-10-29
Completion:
2028-11-30
Conditions
Advanced Breast Cancer
Solid Tumor, Adult
Metastatic Breast Cancer
HER2 Mutation-Related Tumors
HER2-positive Metastatic Breast Cancer
KRAS Mutant Metastatic Colorectal Cancer
Metastatic Lung Cancer
Metastatic Colorectal Cancer
Advanced Lung Cancer
HR-positive, HER2-negative Advanced Breast Cancer
HER2-positive Advanced Breast Cancer
Interventions
DRUG
No Results Yet
30
Participants
ACT_for Alcohol Use Disorder and Depression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-05-01
Completion:
2026-12-01
Conditions
Depression - Major Depressive Disorder
Alcohol Use Disorder
Interventions
BEHAVIORAL
DRUG
No Results Yet
46
Participants
Additional Effects of Surface Electromyographic Biofeedback on Post Facilitation Stretching and Strengthening in Lower Crossed Syndrome;A Randomized Control Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-07-18
Completion:
2025-06-02
Conditions
Lower Cross Syndrome
Interventions
OTHER
No Results Yet
16
Participants
Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-02-02
Completion:
2026-11-30
Conditions
End Stage Renal Disease
Fatigue
Interventions
DRUG
No Results Yet
750
Participants
A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-10-21
Completion:
2030-01-31
Conditions
Pancreatic Ductal Adenocarcinoma
Non-small Cell Lung Cancer
Colorectal Cancer
Advanced Solid Tumor
Metastatic Solid Tumor
Interventions
DRUG
No Results Yet
350
Participants
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-12-11
Completion:
2027-06-30
Conditions
Moderately to Severely Active Ulcerative Colitis
Interventions
DRUG
No Results Yet
25
Participants
KYSA-8: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Treatment Refractory Stiff Person Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-25
Completion:
2026-04-30
Conditions
Stiff-Person Syndrome
SPS
Interventions
BIOLOGICAL
No Results Yet
630
Participants
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-12
Completion:
2029-03-31
Conditions
Pancreatic Ductal Adenocarcinoma
Non-small Cell Lung Cancer
Colorectal Cancer
Interventions
DRUG
No Results Yet
376
Participants
A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-13
Completion:
2025-11-21
Conditions
Obesity
Overweight
Interventions
DRUG
No Results Yet
179
Participants
A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-04
Completion:
2028-02-14
Conditions
Lupus Erythematosus, Systemic
Lupus Nephritis
Interventions
BIOLOGICAL
No Results Yet
24
Participants
Effects of Ghrelin Administration on Motivation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-02
Completion:
2024-12-20
Conditions
Major Depressive Disorder
Interventions
DRUG
No Results Yet
250
Participants
Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-08-26
Completion:
2026-12-31
Conditions
Asthma
Interventions
DRUG
No Results Yet
60
Participants
The Plastic Exposure Reduction Transforms Health Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-05
Completion:
2025-07-03
Conditions
Endocrine Disruptors
Inflammation
Cardiometabolic Risk Factors
Interventions
BEHAVIORAL
No Results Yet
150
Participants
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-01-20
Completion:
2028-02-29
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
200
Participants
A Study to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy (MSA): A Safety and Efficacy Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-10-02
Completion:
2027-05-20
Conditions
Multiple System Atrophy
Interventions
DRUG
No Results Yet
100
Participants
Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-11-12
Completion:
2026-04-15
Conditions
Colorectal Cancer Metastatic
Interventions
DRUG
No Results Yet
538
Participants
Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-17
Completion:
2028-08-31
Conditions
Non Small Cell Lung Cancer
Epidermal Growth Factor Receptor Gene Mutation
Stage III Lung Cancer
Stage IV Lung Cancer
Interventions
DRUG
No Results Yet
10212
Participants
An Extension and Crossover Vaccination Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 60 Years of Age and Above Who Participated in RSV OA=ADJ-006 Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-08-01
Completion:
2026-09-30
Conditions
Respiratory Syncytial Virus Infections
Interventions
BIOLOGICAL
No Results Yet
11000
Participants
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-08-13
Completion:
2028-08-30
Conditions
Kidney Disease, Chronic
Interventions
DRUG
No Results Yet
50
Participants
Initial Resuscitation for Acute Kidney Injury in Cirrhosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-12
Completion:
2026-09-30
Conditions
Cirrhosis, Liver
Acute Kidney Injury
Hepatorenal Syndrome
Interventions
OTHER
No Results Yet
600
Participants
Prediction of Decompensation and HCC Development in Advanced Chronic Liver Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-01
Completion:
2027-09-30
Conditions
Liver Diseases
Hepatocellular Carcinoma
Hepatocarcinoma
Advanced Chronic Liver Disease
Interventions
OTHER
No Results Yet
60
Participants
Comparing the Gastric Emptying Times of Underweight and Healthy-weight School-aged Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-07-30
Completion:
2025-12-15
Conditions
Preoperative Fasting
Interventions
DRUG
No Results Yet
560
Participants
TIDE Project: Biomarker Discovery for Chronic Tinnitus Diagnosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-08-01
Completion:
2025-11-30
Conditions
Tinnitus
Interventions
OTHER
No Results Yet
60
Participants
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-02-27
Completion:
2029-10-30
Conditions
Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm
Interventions
OTHER
PROCEDURE
DRUG
No Results Yet
140
Participants
Ketorolac Effects on Post-operative Pain and Lumbar Fusion
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-01-31
Completion:
2027-06-30
Conditions
Lumbar Spinal Fusion
Interventions
DRUG
No Results Yet
250
Participants
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-18
Completion:
2027-08-24
Conditions
Large B-cell Lymphoma
Interventions
GENETIC
DRUG
DEVICE
No Results Yet
116
Participants
A Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-24
Completion:
2025-02-27
Conditions
Dry Eye Disease
Interventions
DRUG
No Results Yet
100
Participants
ANG-First Trial (Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-05-06
Completion:
2026-01-31
Conditions
Vasodilatory Hypotension During or After Cardiac Surgery
Interventions
DRUG
No Results Yet
200
Participants
A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-10-09
Completion:
2027-07-06
Conditions
Diffuse Cutaneous Systemic Sclerosis
Interventions
DRUG
No Results Yet
20
Participants
Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2025-05-27
Completion:
2026-06-30
Conditions
Breast Neoplasms
No Results Yet
420
Participants
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-07-01
Completion:
2027-05-31
Conditions
Metastatic Solid Tumor
Recurrent Solid Tumor
Advanced Solid Tumor
Urinary Bladder Neoplasm
Triple Negative Breast Cancer
Non-small Cell Lung Cancer
Esophageal Cancer
Pancreatic Cancer
Ovarian Cancer
Cervical Cancer
Head and Neck Squamous Cell Carcinoma
Prostate Cancer
Renal Pelvis Cancer
Bladder Cancer
Interventions
DRUG
No Results Yet
50
Participants
Adapting and Piloting Acceptance and Commitment Therapy (ACT) for Severe Premenstrual Mood Symptoms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-12-01
Completion:
2026-06-30
Conditions
Premenstrual Dysphoric Disorder
Premenstrual Exacerbation of Mood Disorder
Interventions
BEHAVIORAL
No Results Yet
4000
Participants
Master Framework For Relapse or Refractory Acute Myeloid Leukemia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-28
Completion:
2032-07-31
Conditions
Acute Myeloid Leukemia, in Relapse
Acute Myeloid Leukemia Refractory
Interventions
OTHER
No Results Yet
278
Participants
A Study to Learn More About How Well Sevabertinib (BAY 2927088) Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-08-28
Completion:
2027-10-28
Conditions
Advanced Non-small Cell Lung Cancer
HER2 Mutation
Interventions
DRUG
No Results Yet
1130
Participants
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-05-24
Completion:
2027-05-15
Conditions
Colorectal Cancer
CRC
Pancreatic Ductal Adenocarcinoma
PDAC
Gastrointestinal Cancer
Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
192
Participants
Patient's Perspective on the Evolution of Hidradenitis Suppurativa Burden After Secukinumab Initiation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-17
Completion:
2027-06-30
Conditions
Hidradenitis Suppurativa
Interventions
OTHER
No Results Yet
400
Participants
Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-02-26
Completion:
2035-02-27
Conditions
Systemic Lupus
Autoimmune Diseases
Autoinflammatory Disease
Genetic Disease
Interventions
GENETIC
OTHER
No Results Yet
154
Participants
Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-12
Completion:
2026-12-14
Conditions
Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)
Interventions
DRUG
No Results Yet
7
Participants
NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-05-31
Completion:
2025-08-12
Conditions
Advanced Cholangiocarcinoma
Metastatic Cholangiocarcinoma
Refractory Cholangiocarcinoma
Stage III Hilar Cholangiocarcinoma AJCC v8
Stage III Intrahepatic Cholangiocarcinoma AJCC v8
Stage IV Hilar Cholangiocarcinoma AJCC v8
Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
Interventions
PROCEDURE
BIOLOGICAL
No Results Yet
324
Participants
Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-05-22
Completion:
2025-09-22
Conditions
Behavior Problem
Interventions
DRUG
No Results Yet
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