Clinical Trials Updated in 2025

NCT06349057 | RECRUITING | PHASE4

120 Participants

The Effect of the Anticholinergic Burden Following Elective Coronary Artery Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-01-01

Completion: 2025-10-01

Conditions

Postoperative Recovery Length of Hospital Stay Postoperative Complications

Interventions

DRUG

No Results Yet

NCT06346392 | RECRUITING | PHASE3

572 Participants

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-03-04

Completion: 2026-05-14

Conditions

Gastric Cancer Gastroesophageal Junction Cancer

Interventions

DRUG

No Results Yet

NCT06344104 | ACTIVE_NOT_RECRUITING | PHASE3

326 Participants

A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-04-08

Completion: 2025-11-24

Conditions

Uncontrolled Hypertension Resistant Hypertension

Interventions

DRUG

No Results Yet

NCT06342908 | RECRUITING | PHASE1

6 Participants

A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-06-14

Completion: 2027-03-08

Conditions

Diffuse Hemispheric Glioma, H3 G34-Mutant

Interventions

PROCEDURE BIOLOGICAL DRUG

No Results Yet

NCT06341452 | RECRUITING | NA

130 Participants

Comparison of Individualized Sodium Management Versus Standard Treatment in Hemodialysis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-12-16

Completion: 2026-12-31

Conditions

End Stage Renal Disease

Interventions

DEVICE

No Results Yet

NCT06332144 | COMPLETED | NA

41 Participants

Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-01-13

Completion: 2025-08-31

Conditions

Autism Spectrum Disorder Language Development Literacy

Interventions

BEHAVIORAL

No Results Yet

NCT06331312 | RECRUITING | PHASE3

288 Participants

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-06-28

Completion: 2028-08-22

Conditions

Polymyalgia Rheumatica

Interventions

BIOLOGICAL

No Results Yet

NCT06330064 | RECRUITING | PHASE2

520 Participants

A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-04-10

Completion: 2028-07-25

Conditions

Recurrent or Metastatic Solid Tumors

Interventions

DRUG

No Results Yet

NCT06329375 | RECRUITING | NA

160 Participants

Food Insecurity Reduction & Strategy Team

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-10-07

Completion: 2026-03-31

Conditions

Diabetes Mellitus, Type 2 Food Insecurity Diabetes Mellitus, Type 1

Interventions

OTHER

No Results Yet

NCT06327074 | ACTIVE_NOT_RECRUITING | NA

40 Participants

Testing the Engaged Approach to Lung Cancer Screening

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-03-11

Completion: 2024-10-30

Conditions

Lung Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06324357 | RECRUITING | PHASE1/PHASE2

768 Participants

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-06-03

Completion: 2029-01-08

Conditions

Metastatic Breast Cancer Metastatic Gastric Adenocarcinoma Gastroesophageal Junction Adenocarcinoma Esophageal Adenocarcinoma Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06323109 | RECRUITING

80 Participants

US Imaging for the Assessment of LUTS

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2023-11-28

Completion: 2027-01-31

Conditions

Lower Urinary Tract Symptoms BPH

Interventions

DEVICE

No Results Yet

NCT06315556 | RECRUITING

200 Participants

An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2024-03-05

Completion: 2027-03-31

Conditions

Retinopathy of Prematurity Preterm Infants

Interventions

DRUG

No Results Yet

NCT06310005 | COMPLETED | PHASE1

36 Participants

A Study in Healthy Japanese Men to Test How Well Different Doses of BI 3006337 Are Tolerated

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-04-19

Completion: 2024-10-31

Conditions

Healthy

Interventions

DRUG

Results Available

NCT06306586 | RECRUITING | NA

60 Participants

A Digital Treatment for Adolescents With Eating Disorders

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-03-11

Completion: 2027-01-01

Conditions

Eating Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06302439 | RECRUITING

1000 Participants

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2024-07-25

Completion: 2034-05-31

Conditions

Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency ATP-Binding Cassette Subfamily C Member 6 Deficiency

Interventions

OTHER

No Results Yet

NCT06296641 | SUSPENDED | NA

60 Participants

Needs Navigation for Caregivers of AYAs

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-02-16

Completion: 2026-07-31

Conditions

Cancer in Adolescence

Interventions

BEHAVIORAL

No Results Yet

NCT06270602 | RECRUITING

15000 Participants

The ONCOCAMP Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2023-07-14

Completion: 2026-05-31

Conditions

Oncology

Interventions

OTHER

No Results Yet

NCT06266338 | RECRUITING | PHASE2

30 Participants

Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-03-11

Completion: 2026-10-31

Conditions

Cervix Cancer Cervical Cancer

Interventions

DRUG

No Results Yet

NCT06255353 | COMPLETED | NA

118 Participants

Effect of Different Feeding Modes in Intracerebral Hemorrhage

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-02-28

Completion: 2025-10-19

Conditions

Intracerebral Hemorrhage

Interventions

DEVICE BEHAVIORAL

No Results Yet

NCT06249984 | RECRUITING | NA

80 Participants

Effects of Tobacco Cut and Nicotine Form on the Abuse Liability of Moist Snuff

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-12-20

Completion: 2027-03-01

Conditions

Tobacco-Related Carcinoma

Interventions

PROCEDURE BEHAVIORAL OTHER

No Results Yet

NCT06247189 | RECRUITING | NA

30 Participants

ICOPE Program Feasibility in the Management of Myeloma Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-12-03

Completion: 2026-12-03

Conditions

Frailty Multiple Myeloma

Interventions

OTHER

No Results Yet

NCT06246643 | ACTIVE_NOT_RECRUITING | PHASE2

13 Participants

A Study of Continued Treatment With Regorafenib in Participants With Solid Tumors Who Have Participated in Other Bayer Studies

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-01-24

Completion: 2028-04-27

Conditions

Solid Malignant Tumors

Interventions

DRUG

No Results Yet

NCT06244212 | RECRUITING | NA

30 Participants

Topical Treatment for Atopic Dermatitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-09-19

Completion: 2026-07-31

Conditions

Atopic Dermatitis

Interventions

OTHER BEHAVIORAL

No Results Yet

NCT06240208 | RECRUITING | NA

40 Participants

Physical Inactivity and Appetite Regulation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-03-01

Completion: 2026-02-01

Conditions

Overweight

Interventions

BEHAVIORAL

No Results Yet

NCT06239116 | RECRUITING | PHASE1/PHASE2

150 Participants

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-03-05

Completion: 2027-11-01

Conditions

Hypothalamic Obesity Prader-Willi Syndrome PWS

Interventions

DRUG

No Results Yet

NCT06229366 | ACTIVE_NOT_RECRUITING | PHASE1

142 Participants

[Ac-225]-PSMA-62 Trial in Oligometastatic Hormone Sensitive and Metastatic Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-04-03

Completion: 2027-09-30

Conditions

Prostate Cancer Metastatic Castration-resistant Prostate Cancer Oligometastatic Prostate Carcinoma Hormone Sensitive Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06228053 | RECRUITING | PHASE2

53 Participants

Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-11-18

Completion: 2026-06-30

Conditions

Metastatic Castration-resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06218511 | ACTIVE_NOT_RECRUITING | PHASE1

10 Participants

A Phase I Trial of IMA970A Plus Montanide in Combination With Durvalumab (Anti-PD-L1)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2022-11-22

Completion: 2025-08-28

Conditions

Hepatocellular Carcinoma

Interventions

BIOLOGICAL COMBINATION_PRODUCT OTHER

No Results Yet

NCT06210061 | COMPLETED | NA

78 Participants

Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-01-20

Completion: 2025-03-01

Conditions

Propofol Fentanyl Dexmedetomidine Sevoflurane Spine Surgery Somatosensory Evoked Potential Motor Evoked Potential

Interventions

DRUG

No Results Yet

NCT06192758 | SUSPENDED | NA

36 Participants

Dose Escalation Study Evaluating Safety of TheraSphere Prostate Cancer (PCa) Device

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-04-15

Completion: 2028-01-31

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT06191575 | SUSPENDED

10 Participants

7 Tesla MRI Neuroimaging in Testicular Cancer Patients With Hypogonadism and on Androgen Replacement Therapy

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2022-11-29

Completion: 2026-12-31

Conditions

Hypogonadism Malignant Testicular Germ Cell Tumor

Interventions

PROCEDURE

No Results Yet

NCT06179784 | COMPLETED | NA

12 Participants

Personalising Psychotherapy for Chronic Primary Pain Using Network Analysis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2023-11-17

Completion: 2025-08-08

Conditions

Chronic Primary Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06173154 | COMPLETED | NA

85 Participants

Feasibility Assessment of Implementing a Care System to PREVENT Iatrogenic Dependency (ID)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-06-12

Completion: 2025-05-20

Conditions

Aged

Interventions

OTHER

No Results Yet

NCT06170671 | ACTIVE_NOT_RECRUITING

250 Participants

REAl-world Outcomes in CHronic Lymphocytic Leukemia Patients Receiving Acalabrutinib in Romania

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2023-12-13

Completion: 2028-09-30

Conditions

Chronic Lymphocytic Leukemia

Interventions

DRUG

No Results Yet

NCT06170619 | COMPLETED

125 Participants

Obsidio™ Conformable Embolic Registry

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2024-06-19

Completion: 2025-09-09

Conditions

Bleeding Hemorrhage Hypervascular Tumors

Interventions

DEVICE

No Results Yet

NCT06167213 | NOT_YET_RECRUITING | NA

125 Participants

ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2027-01-31

Completion: 2029-03-31

Conditions

Mitral Regurgitation Mitral Valve Disease Mitral Stenosis

Interventions

DEVICE

No Results Yet

NCT06166810 | RECRUITING

10 Participants

Capture of Healthy Gut Bacteria Associated to High Fiber Diet

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2023-10-24

Completion: 2025-12-31

Conditions

General Population

No Results Yet

NCT06164587 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

30 Participants

Evaluation of Kamuvudine-8 in Subjects With Geographic Atrophy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-04-18

Completion: 2026-06-30

Conditions

Geographic Atrophy Age-Related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT06161818 | RECRUITING | PHASE2

216 Participants

Total Neoadjuvant Therapy for Lymph Node-positive Adenocarcinoma of the OESophagus and Oesophagogastric Junction

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-09-12

Completion: 2029-09-01

Conditions

Esophageal Cancer Adenocarcinoma of the Esophagus

Interventions

DRUG

No Results Yet