Clinical Trials
Showing trials with last updates posted in 2025.
188
Participants
Fluid Management and Individualized Resuscitation in Sepsis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-09-01
Completion:
2026-09-01
Conditions
Sepsis
Shock
Personalized Medicine
Emergency Medicine
Critical Care, Fluid Resuscitation
Fluid Responsiveness
Interventions
OTHER
No Results Yet
3500
Participants
Smart Angioplasty Research Team-Coronary CT Angiography Versus Standard Care as Follow-up Strategies in High-Risk Patients After PCI (SMART-CARE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-10-02
Completion:
2031-12-31
Conditions
Ischemic Heart Disease
Coronary Artery Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
102
Participants
Efficacy of Notrande Shuhuajun Probiotic Supplement on Lmproving Constipation in Preschool Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-05-30
Completion:
2025-08-24
Conditions
Functional Constipation (FC)
Interventions
DIETARY_SUPPLEMENT
No Results Yet
15
Participants
UI-Romi-02; Romiplostim Added to Standard of Care for Treatment Naive and Relapsed or Refractory Severe Aplastic Anemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2026-08-01
Completion:
2031-12-31
Conditions
Aplastic Anemia
Interventions
DRUG
No Results Yet
60
Participants
Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Acute Pancreatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-05-15
Completion:
2025-11-20
Conditions
Acute Pancreatitis (AP)
Vagus Nerve Stimulations
Interventions
DEVICE
No Results Yet
152
Participants
A Platform Study in Non-Small Cell Lung Cancer (NSCLC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-11-24
Completion:
2029-02-23
Conditions
Advanced or Metastatic Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
25
Participants
Characteristics of Adult Patients With Melanoma Diagnosis <40 Years Age.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2025-12-02
Completion:
2027-09-01
Conditions
Melanoma of Skin
No Results Yet
47
Participants
A Study to Test How Well Multiple Doses of BI 3810477 Are Tolerated by Healthy Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-06-06
Completion:
2026-03-09
Conditions
Healthy
Interventions
DRUG
No Results Yet
48
Participants
Safety and Pharmacokinetics of LPX-TI641 in Atopic Dermatitis and Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-06-15
Completion:
2026-01-15
Conditions
Atopic Dermatitis (AD)
Psoriasis (PsO)
Interventions
DRUG
No Results Yet
192
Participants
The Efficacy and Safety of Rilzabrutinib in Patients Aged 10 to 65 Years With Sickle-cell Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-08-12
Completion:
2027-07-23
Conditions
Sickle Cell Disease
Interventions
DRUG
No Results Yet
15
Participants
Study to Investigate the Health Benefits of a Quercetin/Curcumin-Based Supplement for Mild to Moderate Long COVID-19 Symptoms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-07-22
Completion:
2025-11-18
Conditions
Long COVID
Interventions
DIETARY_SUPPLEMENT
No Results Yet
150
Participants
Effect of the "Sitting Out of Bed in an Arm-chair Position" in ICU on Functional Recovery Among Ventilated Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-07-04
Completion:
2028-01-31
Conditions
ICU Acquired Weakness
Interventions
OTHER
No Results Yet
200
Participants
Validation of the Sentinel Lymph Node Technique in Early-stage Ovarian Cancer (SENTOV II)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-11-10
Completion:
2028-06-30
Conditions
Ovarian Neoplasms
Interventions
PROCEDURE
No Results Yet
285
Participants
A Long-term Study to Monitor the Health Status of People With Cystic Fibrosis Who Took Part in a Previous Study With BI 3720931 (Lenticlair™-ON)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-05-20
Completion:
2048-11-24
Conditions
Cystic Fibrosis
Interventions
GENETIC
No Results Yet
150
Participants
Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2025-04-24
Completion:
2028-01-01
Conditions
Soft Tissue Sarcoma
Interventions
PROCEDURE
No Results Yet
200
Participants
Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-06-17
Completion:
2027-06-30
Conditions
Balance Control in Elderly
Gait Disorders
Peripheral Neuropathies
Peripheral Neuropathy Due to Chemotherapy
Peripheral Neuropathy With Type 2 Diabetes
Interventions
DEVICE
OTHER
No Results Yet
40
Participants
Impact of Metabolic Syndrome on Rehabilitation Outcomes in Rotator Cuff Injury
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2025-04-15
Completion:
2025-06-15
Conditions
Rotator Cuff Injury (RCI)
Metabolic Syndrome (MetS)
No Results Yet
40
Participants
GMP Powdered Substitutes in PKU and TYR
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-05-20
Completion:
2026-12-31
Conditions
Phenylketonuria
Tyrosinemia
Interventions
DIETARY_SUPPLEMENT
No Results Yet
20
Participants
Intraoperative Parathyroid Gland (PTG) Identification Using a Hand-Held Imager (HHI)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-09-01
Completion:
2025-08-28
Conditions
Thyroid Disease
Thyroid Surgery
Parathyroid Gland
Interventions
DEVICE
DRUG
No Results Yet
70
Participants
Effects of Cycle Therapy vs Sequential Therapy With Romosozumab and Denosumab in Postmenopausal Osteoporosis Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-04-08
Completion:
2029-04-30
Conditions
Osteoporosis
Osteoporosis Postmenopausal
Interventions
DRUG
No Results Yet
46
Participants
Postoperative Analgesia With an Erector Spinae Plane Block in Robotic-assisted Partial Nephrectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-05-15
Completion:
2025-08-15
Conditions
Analgesia
Interventions
PROCEDURE
No Results Yet
64
Participants
Evaluation of the Safety, Tolerability and Pharmacokinetics of AH-001 Following Topical Single and Multiple Ascending Dose Administration
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-03-24
Completion:
2025-07-16
Conditions
Androgenetic Alopecia
Interventions
DRUG
No Results Yet
60
Participants
Utilization of Virtual Reality to Increase Comfort and Reduce Procedural Distress During Port Insertion Into the Body
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-07-01
Completion:
2026-07-31
Conditions
Oncology Patients
Interventions
PROCEDURE
No Results Yet
220
Participants
A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-09-10
Completion:
2028-04-06
Conditions
Non-Muscle Invasive Bladder Neoplasms
Interventions
DRUG
No Results Yet
50
Participants
A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-08-15
Completion:
2026-08-31
Conditions
Apathy
Loneliness
Reminiscence Therapy
Interventions
BEHAVIORAL
No Results Yet
100
Participants
Treatment of Antibody-Mediated Rejection (ABMR) With CarBel
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2026-01-15
Completion:
2027-06-30
Conditions
Kidney Transplant Rejection
Interventions
BIOLOGICAL
No Results Yet
30
Participants
Comparison of the Effects of Robotic Rehabilitation, Functional Electrical Stimulation and Occupational Therapy on Upper Extremity and Hand Functions in Tetraplegic Patients With Spinal Cord Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-04-01
Completion:
2025-09-01
Conditions
Tetraplegia/Tetraparesis
Interventions
DEVICE
OTHER
No Results Yet
104
Participants
Daily Nitrofurantoin Versus Bladder Fulguration Plus Daily Nitrofurantoin for Women With Recurrent Urinary Tract Infections
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2026-01-31
Completion:
2028-07-01
Conditions
Recurrent UTIs
Cystitis Recurrent
Interventions
PROCEDURE
DRUG
No Results Yet
363
Participants
Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2025-03-17
Completion:
2026-06-30
Conditions
Social Isolation or Loneliness
Anxiety
Anxiety Depression (Mild or Not Persistent)
Health Behavior
Observational Study
Stress, Psychological
Emotional Stress
Life Stress
Psychological Stress
Stress, Emotional
Stress (Psychology)
Substance Abuse
Substance Addiction
Substance Dependence
Substance Use
No Results Yet
250
Participants
Consistency of Response With Rimegepant in Acute Treatment of Migraine
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2025-11-15
Completion:
2026-06-30
Conditions
Migraine
Interventions
DRUG
No Results Yet
100
Participants
Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-07-08
Completion:
2034-06-01
Conditions
Mesothelioma
Neoplasms
Stomach Neoplasms
Pancreatic Neoplasms
Ovarian Neoplasms
Lung Neoplasms
Thymus Neoplasms
Colonic Neoplasms
Interventions
DEVICE
BIOLOGICAL
DRUG
No Results Yet
358
Participants
Effectiveness of Visual Storytelling Intervention on Antibiotic Adherence in UTI Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-06-03
Completion:
2025-08-30
Conditions
Uncomplicated Urinary Tract Infection
Patient With Uncomplicated UTI
Interventions
BEHAVIORAL
No Results Yet
540
Participants
A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-02-21
Completion:
2026-05-27
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
285
Participants
Thoraco Lumbar Vertebral Length and Bupivacaine Dosage in C-Section
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-05-20
Completion:
2025-12-01
Conditions
Obstetric Anesthesia Problems
Bupivacaine Adverse Reaction
Interventions
PROCEDURE
No Results Yet
53
Participants
Clinical Evaluation of Two Cosmetic Contact Lenses
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-03-30
Completion:
2025-05-05
Conditions
Visual Acuity
Interventions
DEVICE
No Results Yet
76
Participants
Acupuncture for ADHD: Acupoint Data Mining, Clinical Effectiveness, and Interviews to Explore Treatment Outcomes.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-10-15
Completion:
2026-04-15
Conditions
Acupuncture
ADHD - Attention Deficit Disorder With Hyperactivity
Children
Interview
Executive Functioning
Quality of Life (QOL)
Interventions
DRUG
DEVICE
No Results Yet
82
Participants
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-1301 in Healthy Subjects
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-03-18
Completion:
2025-08-11
Conditions
Hyperlipidemia
Interventions
DRUG
No Results Yet
36000
Participants
Cities for Better Health Childhood Obesity Prevention Initiative
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-04-30
Completion:
2027-12-31
Conditions
Obesity
Interventions
BEHAVIORAL
No Results Yet
600
Participants
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-06-04
Completion:
2029-06-22
Conditions
Leukemia, Myeloid, Acute
Interventions
DRUG
No Results Yet
144
Participants
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-03-03
Completion:
2027-08-31
Conditions
Obese or Overweight Healthy Volunteers
Type 2 Diabetes Mellitus (T2DM)
Interventions
DRUG
No Results Yet
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