Clinical Trials
Showing trials with last updates posted in 2025.
37
Participants
A Study to Investigate the Course of Synovial Hypertrophy in Patients With Haemophilia A on Efanesoctocog Alfa Prophylaxis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-19
Completion:
2026-12-31
Conditions
Haemophilia A (Moderate or Severe)
Hemophilia, Classic
Haemophilia
Hemophilia
Classic Hemophilia
Synovial Hypertrophy
Interventions
DRUG
No Results Yet
400
Participants
Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-03-28
Completion:
2027-11-02
Conditions
Eosinophilic Asthma
Interventions
COMBINATION_PRODUCT
No Results Yet
700
Participants
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-12
Completion:
2027-12-15
Conditions
Colorectal Neoplasms
Interventions
BIOLOGICAL
DRUG
No Results Yet
134
Participants
Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-01-07
Completion:
2025-03-20
Conditions
Astigmatism
Interventions
DEVICE
No Results Yet
500
Participants
Biobank Cardiac Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-12-18
Completion:
2028-12-31
Conditions
Cardiovascular Diseases
Interventions
PROCEDURE
No Results Yet
234
Participants
Speech-to-speech Voice-cloning Care (SVCC) to Improve ICU-acquired Anxiety for Critically Ill Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2026-01-01
Completion:
2026-10-31
Conditions
Critical Care Nursing
Interventions
BEHAVIORAL
No Results Yet
50
Participants
Study Designed to Assess the Safety and Feasibility of the Levita Magnetic Surgical System in Laparoscopic Gynecological Procedures
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-30
Completion:
2026-05-07
Conditions
Gynecological Laparoscopic Surgery
Interventions
DEVICE
No Results Yet
600
Participants
Nipocalimab in Moderate to Severe Sjogren's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-04
Completion:
2028-01-01
Conditions
Sjogrens Syndrome
Interventions
DRUG
No Results Yet
60
Participants
Topical 5-Fluorouracil (5FU) Plus Calcipotriol in Children With Palmoplantar Wart
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-05-30
Completion:
2026-07-01
Conditions
Common Warts
Interventions
DRUG
No Results Yet
28
Participants
Influence of Metabolic Syndrome on Endogenous Oxalate Synthesis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-04-26
Completion:
2026-12-31
Conditions
MASLD
Metabolic Dysfunction-Associated Steatotic Liver Disease
Interventions
DIETARY_SUPPLEMENT
No Results Yet
4
Participants
Single Case Research Design: Teacher Outcomes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-08-23
Completion:
2025-07-01
Conditions
Teacher Practice
Interventions
BEHAVIORAL
21
Participants
Efficacy, Safety, PK, PD, and ADA of Eculizumab in Chinese Adults With NMOSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-01-16
Completion:
2026-12-07
Conditions
NMOSD
Neuromyelitis Optica Spectrum Disorders
Interventions
DRUG
No Results Yet
100
Participants
Diarrheal Adverse Events in Caucasian Patients With Idiopathic Pulmonary Fibrosis Undergoing Treatment With Nintedanib
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-20
Completion:
2023-12-31
Conditions
IPF
No Results Yet
60
Participants
Feasibility Trial of a Guided Internet-delivered Intervention for Adolescents With ADHD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-11-18
Completion:
2027-01-01
Conditions
ADHD
Interventions
BEHAVIORAL
No Results Yet
250
Participants
Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-01-29
Completion:
2028-01-26
Conditions
Solid Tumors
Gastric Cancer
Non-Small Cell Lung Cancer (NSCLC)
Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions
DRUG
No Results Yet
0
Participants
Postsurgical Analgesia After Hernia Repair
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-01-27
Completion:
2026-03-31
Conditions
Hernia Repair
Hernia Inguinal
Hernia Surgery
Hernia, Inguinal/Surgery
Hernia, Inguinal
Interventions
DRUG
OTHER
No Results Yet
[Trial of device that is not approved or cleared by the U.S. FDA]
Last Updated:
2025-12-19
No Results Yet
2280
Participants
Enhancing Cervical Cancer Screening and Treatment in Women Living With HIV in Kenya, the ENHANCE LINKAge Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2026-03-31
Completion:
2029-08-31
Conditions
HIV Infection
Human Papillomavirus-Related Cervical Carcinoma
Screening Strategy
Interventions
OTHER
PROCEDURE
No Results Yet
2000
Participants
Personalized Evaluation of Susptected Myocardial Ischemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-11-20
Completion:
2027-12-31
Conditions
Chronic Coronary Syndrome
Angina Pectoris
Coronary Artery Disease
Myocardial Ischemia
Arteriosclerosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
458
Participants
Abbott Medical - VERITAS Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-11-11
Completion:
2025-11-04
Conditions
Atrial Fibrillation (AF)
Stoke
Interventions
DEVICE
No Results Yet
3000
Participants
Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-06-21
Completion:
2029-06-30
Conditions
Prostate Cancer
Interventions
PROCEDURE
No Results Yet
123
Participants
Comparison of the Effects of Interscalene Block and Superior Trunk Block on Pulmonary Functions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-01
Completion:
2025-01-11
Conditions
Regional Anesthesia Morbidity
Complication Following Peripheral Nerve Block
Phrenic Nerve Paralysis
Interventions
PROCEDURE
No Results Yet
23
Participants
Digoxin Medulloblastoma Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-12-31
Completion:
2026-02-28
Conditions
Medulloblastoma
Medulloblastoma, Non-WNT/Non-SHH
Interventions
DRUG
No Results Yet
96
Participants
Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall Good Health in South Africa.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-12-17
Completion:
2026-10-30
Conditions
HIV Infections
Interventions
BIOLOGICAL
No Results Yet
32
Participants
Efficacy of Focused Extracorporeal Shock Wave Therapy After Anterior Cruciate Ligament Reconstruction
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-01
Completion:
2026-12-01
Conditions
ACL Reconstruction
Extracorpereal Shock Wave Therapy
Interventions
OTHER
No Results Yet
60
Participants
Continue ESPB & Continue ESPB Combined With SAPB for Thoracotomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-10-18
Completion:
2025-02-10
Conditions
Post-thoracotomy Pain
Interventions
DRUG
No Results Yet
585
Participants
Early Amiodarone in Shockable Cardiac Arrest
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-01-01
Completion:
2027-12-31
Conditions
Cardiac Arrest
Interventions
DRUG
OTHER
No Results Yet
700
Participants
A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-03
Completion:
2028-05-30
Conditions
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Interventions
DRUG
No Results Yet
36
Participants
Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-17
Completion:
2026-12-31
Conditions
Spinocerebellar Ataxia Type 2
Interventions
DRUG
No Results Yet
166
Participants
Effectiveness and Safety of TIPS Stent Graft in the Treatment of Cirrhosis and Complications of Portal Hypertension
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-11-21
Completion:
2026-06-01
Conditions
Portal Hypertension Related to Cirrhosis
Ascites Hepatic
Variceal Bleeding
Interventions
DEVICE
No Results Yet
130
Participants
A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-06
Completion:
2028-12-31
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
BIOLOGICAL
RADIATION
No Results Yet
480
Participants
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-16
Completion:
2029-05-23
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
196
Participants
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-10-29
Completion:
2031-12-12
Conditions
Crohns Disease
Colitis, Ulcerative
Arthritis, Psoriatic
Arthritis, Juvenile
Interventions
DRUG
No Results Yet
1000
Participants
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-10-18
Completion:
2028-12-15
Conditions
Colorectal Neoplasms
Interventions
BIOLOGICAL
DRUG
No Results Yet
120
Participants
A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-11-11
Completion:
2028-01-05
Conditions
Hereditary Hemorrhagic Telangiectasia
Interventions
DRUG
No Results Yet
75
Participants
To Drill or Not to Drill: Do Memory Drills Help Train the Ability to "Remember to Remember" in Veterans
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-10-22
Completion:
2026-09-30
Conditions
Memory Deficit
Interventions
BEHAVIORAL
No Results Yet
240
Participants
Using Artificial Intelligence to Screen for Hip Dysplasia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-06
Completion:
2026-07-31
Conditions
Developmental Dysplasia of Hip
Interventions
DEVICE
No Results Yet
0
Participants
Machine Learning and 3D Image-Based Modeling for Real-Time Body Weight and Body Composition Estimation During Emergency Medical Care: Study 2
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2027-07-01
Completion:
2028-02-28
Conditions
Body Weights and Measures
Body Weight in the Overweight and Obese Class - I Population
Weight Estimation
Emergency Drug Dosing
Interventions
DIAGNOSTIC_TEST
No Results Yet
0
Participants
Machine Learning and 3D Image-Based Modeling for Real-Time Body Weight and Body Composition Estimation During Emergency Medical Care. Study 1
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2025-07-01
Completion:
2026-06-30
Conditions
Body Weights and Measures
Body Weight in the Overweight and Obese Class - I Population
No Results Yet
0
Participants
Machine Learning and 3D Image-Based Modeling for Real-Time Body Weight and Body Composition Estimation During Emergency Medical Care. Study 3
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2029-07-01
Completion:
2029-11-30
Conditions
Body Weights and Measures
Body Weight in the Overweight and Obese Class - I Population
Drug Dose
Weight Estimate
Interventions
OTHER
No Results Yet
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