Clinical Trials
Showing trials with last updates posted in 2025.
1835
Participants
Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-11-07
Completion:
2027-01-22
Conditions
Chronic Kidney Disease With High Proteinuria
Interventions
DRUG
No Results Yet
25
Participants
BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-11-22
Completion:
2034-09-30
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
100
Participants
Sentinel lympH Node Biopsy With Indocyanine Green in Breast Cancer After NEoadjuvant Chemotherapy (SHINE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-09-03
Completion:
2026-04-30
Conditions
Breast Cancer
Interventions
PROCEDURE
No Results Yet
90
Participants
Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-12-20
Completion:
2024-03-20
Conditions
Knee Disease
Knee Deformity
Knee Pain Chronic
Knee Arthropathy
Knee Osteoarthritis
Interventions
DRUG
No Results Yet
100
Participants
A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-13
Completion:
2027-06-30
Conditions
Congenital Myasthenic Syndrome
No Results Yet
113
Participants
Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-09-25
Completion:
2024-12-18
Conditions
Chronic Spontaneous Urticaria
Interventions
DRUG
30
Participants
Blended Reality Immersion for Geriatric Head Trauma: The BRIGHT Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-11-29
Completion:
2025-08-15
Conditions
Traumatic Brain Injury
Interventions
DEVICE
No Results Yet
22
Participants
Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-12
Completion:
2026-12-31
Conditions
Spasticity as Sequela of Stroke
Spastic Cerebral Palsy
Spasticity, Muscle
Interventions
RADIATION
OTHER
No Results Yet
171
Participants
A Study to Evaluate the Effect of Budesonide, Glycopyrronium, Formoterol Fumarate (BGF) Metered Dose Inhaler (MDI), Budesonide and Formoterol Fumarate (BFF) MDI and Placebo MDI on Exercise Parameters in Participants With Chronic Obstructive Pulmonary Disease (COPD).
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-24
Completion:
2026-01-30
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DRUG
No Results Yet
20
Participants
Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-11-20
Completion:
2026-12-31
Conditions
Gastrointestinal Cancer
Interventions
DRUG
No Results Yet
16
Participants
The Gut Microbiome and Immunotherapy Response in Solid Cancers
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-06-30
Completion:
2026-12-30
Conditions
Cancer
No Results Yet
104
Participants
Comparison of Allegra vs Sapien Transcatheter Aortic Valves in Valve-In-Valve Indication
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-01
Completion:
2026-11-01
Conditions
Aortic Valve Stenosis
Structural Valve Deterioration
Interventions
DEVICE
No Results Yet
30
Participants
Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-26
Completion:
2026-06-30
Conditions
Non-small Cell Lung Cancer
Solid Tumors
Programmed Cell Death-1 (PD1, PD-1)
Programmed Cell Death 1 Ligand 1(PDL1, PD-L1)
Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)
Interventions
BIOLOGICAL
DRUG
No Results Yet
252
Participants
A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-09
Completion:
2024-09-26
Conditions
Colitis, Ulcerative
Interventions
DRUG
No Results Yet
24
Participants
Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Solid Tumor Cancers With KRAS G12V Mutations
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-12-15
Completion:
2028-01-01
Conditions
Metastatic Malignant Solid Neoplasm
Interventions
DRUG
PROCEDURE
BIOLOGICAL
No Results Yet
60
Participants
A US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-13
Completion:
2026-10-23
Conditions
Hepatocellular Carcinoma (HCC)
Interventions
DRUG
PROCEDURE
No Results Yet
180
Participants
Testing the Effectiveness of WW Clinic GLP1
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-01-18
Completion:
2024-10-17
Conditions
Weight Loss
Obesity
10
Participants
The Safety and Tolerability Study With ER2001 Intravenous Injection in Adults With Early Manifest Huntington's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-04-04
Completion:
2025-01-31
Conditions
Huntington Disease
Interventions
DRUG
No Results Yet
72
Participants
A Study of CRD3874-SI in People With Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-25
Completion:
2029-08-31
Conditions
Sarcoma
Merkel Cell Carcinoma
Interventions
DRUG
No Results Yet
151
Participants
Predicting Outcome of Cytoreduction in Advanced Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-01-02
Completion:
2025-12-15
Conditions
Ovarian Cancer Stage III
Ovarian Cancer Stage IV
Interventions
DIAGNOSTIC_TEST
No Results Yet
42
Participants
A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP) Who Need Treatment for Repeated Flares
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-22
Completion:
2026-07-23
Conditions
Generalized Pustular Psoriasis
Interventions
DRUG
No Results Yet
568
Participants
COPD Case Finding In Nottingham and District: C-FIND COPD A Pilot Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-09-21
Completion:
2025-12-31
Conditions
COPD
No Results Yet
260
Participants
Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-09-05
Completion:
2027-09-30
Conditions
Marginal Zone Lymphoma
Interventions
DRUG
No Results Yet
84
Participants
Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-29
Completion:
2025-09-22
Conditions
Heart Failure With Preserved Ejection Fraction
Functional Mitral Regurgitation
Interventions
DRUG
No Results Yet
111
Participants
Evaluating a School-based Social and Material Needs Identification System to Prevent Youth Violence Involvement
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-21
Completion:
2025-10-01
Conditions
Violence, Physical
Maltreatment, Child
Interventions
OTHER
No Results Yet
25
Participants
Open Trial of Biofeedback for Respiratory Symptoms
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-08-01
Completion:
2027-07-31
Conditions
Shortness of Breath/Dyspnea
No Results Yet
320
Participants
A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-05-30
Completion:
2027-12-15
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell
Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
21
Participants
Protection Response to Cellular Stress in BPAN's Patient Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-23
Completion:
2025-10-23
Conditions
Children and Adults With BPAN Carrying Pathogenic Variants of WDR45
Interventions
BIOLOGICAL
No Results Yet
47
Participants
Stress-Echography in Hereditary Haemorrhagic Telangiectasia Patient With Hepatic Involvement
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-03
Completion:
2025-01-14
Conditions
Hereditary Hemorrhagic Telangiectasia
Rendu Osler Disease
Interventions
OTHER
No Results Yet
161
Participants
Prospective Clinical Evaluation of BD NRFit™ Devices and Accessories.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-07-24
Completion:
2024-05-28
Conditions
Anesthesia
Analgesia
Interventions
DEVICE
25
Participants
Influence of Gait and Running on Foot Posture
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-06-20
Completion:
2023-06-20
Conditions
Foot Pronation in Healthy Adult
Interventions
BEHAVIORAL
No Results Yet
40
Participants
Pilot Testing of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-01
Completion:
2024-08-05
Conditions
Autism Spectrum Disorder
Parent-Child Relations
Interventions
OTHER
No Results Yet
120
Participants
A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-03-13
Completion:
2027-10-27
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
71
Participants
A Study of Combination Therapy With Amivantamab and Cetrelimab in Participants With Metastatic Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-05-18
Completion:
2026-01-30
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
156
Participants
Weaning With Tracheostomy - an Observational Study on Patient-centered Outcomes
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-05-08
Completion:
2024-11-30
Conditions
Weaning Failure
Mechanical Ventilation
Patient-centered Care
No Results Yet
5
Participants
A Novel Balance Program to Improve Balance in People With Parkinson's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-09-20
Completion:
2023-12-18
Conditions
Rehabilitation Exercise
Physical Therapy
Interventions
OTHER
No Results Yet
420
Participants
A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-31
Completion:
2026-10-12
Conditions
Metastatic Castrate-sensitive Prostate Cancer
Interventions
DRUG
No Results Yet
60
Participants
Serum Concentration of Endogenous Estrogens and Sirtuin-1 After Administration of Atorvastatin and Quercetin:
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-03
Completion:
2023-12-23
Conditions
Coronary Artery Disease
Menopause
Interventions
DIETARY_SUPPLEMENT
No Results Yet
234
Participants
Effect of Partially Hydrolyzed, Whey-based Infant Formulas on Growth and Tolerability in Healthy Term Infants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-17
Completion:
2027-12-31
Conditions
Infant Nutritional Physiological Phenomena
Infant Formula
Infant Health
Infant Development
Growth and Development
Interventions
OTHER
No Results Yet
13
Participants
Grasp-Release Assessment of a Networked Neuroprosthesis Device
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-01-23
Completion:
2027-12-01
Conditions
Spinal Cord Injury at C5-C7 Level
Spinal Cord Injuries
Spinal Cord Injury Cervical
Interventions
DEVICE
No Results Yet
Showing 40 trials per page