Clinical Trials
Showing trials with last updates posted in 2025.
320
Participants
A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-08-13
Completion:
2026-06-25
Conditions
Advanced Cancer
Interventions
DRUG
No Results Yet
474
Participants
Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-05-01
Completion:
2026-09-30
Conditions
Heart Failure
Acute Heart Failure
Interventions
DRUG
No Results Yet
292
Participants
A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Participants 6 to 17 Years of Age
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-24
Completion:
2024-11-29
Conditions
Migraine
Interventions
DRUG
151
Participants
Phase 3 Study of Pyrotinib Versus Docetaxel in Patients With Advanced Non-squamous NSCLC Harboring a HER2 Exon 20 Mutation Who Failed Platinum Based Chemotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-11
Completion:
2023-06-02
Conditions
Non-squamous NSCLC
HER2 Exon 20 Mutation
Interventions
DRUG
No Results Yet
60
Participants
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-04
Completion:
2027-08-31
Conditions
Pain, Postoperative
Pain, Chronic
Pain, Acute
Surgical Injury
Surgical Wound
Cornea Injury
Cornea
Keratoconus
No Results Yet
15
Participants
Renal Metabolism of Glycolate to Oxalate
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-03-12
Completion:
2026-09-01
Conditions
Healthy
Interventions
DIETARY_SUPPLEMENT
OTHER
No Results Yet
1000
Participants
Screening for NAFLD-related Advanced Fibrosis in High Risk Population in Diabetology.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-10-28
Completion:
2023-10-28
Conditions
Non-Alcoholic Fatty Liver Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
20
Participants
Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-08-31
Completion:
2025-12-31
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
0
Participants
Intermediate IND Severe Illness COVID-19 CP
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-04-07
Completion:
2021-04-07
Conditions
Severe Acute Respiratory Syndrome
COVID
Interventions
DRUG
No Results Yet
255
Participants
Improving Spine Surgical Care With Real-Time Objective Patient Tracking Using the Apple Watch
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-01
Completion:
2024-11-30
Conditions
Spine Disease
Spine Degeneration
Spinal Stenosis
Surgery
Spine Fusion
Interventions
DEVICE
141
Participants
Appalachian Partnership to Reduce Disparities (Aim 2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-04-01
Completion:
2026-05-31
Conditions
HIV/AIDS
STI
HCV
Interventions
BEHAVIORAL
No Results Yet
0
Participants
The Effect of Adding Lubiprostone to Standard Large-Volume PEG-ELS on The Quality of Inpatient Colonoscopy Preparation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2020-05-01
Completion:
2021-02-04
Conditions
Colonoscopy Preparation
Interventions
DRUG
No Results Yet
500
Participants
Long Term Outcomes of Patients With COVID-19
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2020-04-08
Completion:
2026-06-01
Conditions
Critical Illness
Corona Virus Infection
Respiratory Failure
Covid-19
Interventions
OTHER
No Results Yet
150
Participants
Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-08-01
Completion:
2027-09-01
Conditions
Traumatic Brain Injury
Interventions
BEHAVIORAL
No Results Yet
31
Participants
A Study of Apalutamide Combined With GnRH Agonist in Participants With Androgen Receptor Positive Salivary Gland Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-04-07
Completion:
2021-06-09
Conditions
Salivary Gland Neoplasms
Interventions
DRUG
40
Participants
Impact of Tooth Loss and Denture on Oral Senses and Food Preferences
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-03-16
Completion:
2027-04-30
Conditions
Tooth-loss
Interventions
PROCEDURE
No Results Yet
20
Participants
Evaluating Mobility Interventions in the Real World
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-09-03
Completion:
2024-08-01
Conditions
Lower Limb Amputation
Drop Foot
Interventions
DEVICE
71
Participants
Vascular Effects of Acute Sodium (VEAS) Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-05-03
Completion:
2025-12-15
Conditions
Sodium Excess
Racial Disparities
Blood Pressure
Cardiovascular Risk Factor
Interventions
OTHER
No Results Yet
1019
Participants
If Chronic Gallbladder Diseases Increase the Incidence of PEC
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2020-02-14
Completion:
2024-11-16
Conditions
Cholecystitis
Interventions
PROCEDURE
No Results Yet
275
Participants
A Research Study Investigating Mim8 in People With Haemophilia A
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-01-10
Completion:
2023-10-06
Conditions
Healthy Volunteers
Haemophilia A With or Without Inhibitors
Interventions
DRUG
No Results Yet
100
Participants
Comparison of Two Exercise Training Modes on Left Myocardial Regional Function After Myocardial Infarction Evaluated by 2D Strain Ultrasound
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-03-12
Completion:
2023-07-20
Conditions
Ischemic Cardiomyopathy
Interventions
OTHER
No Results Yet
328
Participants
MiDura-Study (Neuro-Patch in Duraplasty)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2020-02-06
Completion:
2026-02-28
Conditions
Meningioma
Tumor, Brain
Chiari Malformation
Vascular Malformation
Hydrocephalus
Tethered Cord
Dural Fistula
Craniotomy
Spinal Surgery
Duraplasty
No Results Yet
90
Participants
Epigenetic Effects in Children With Cow's Milk Allergy Treated With Different Formulas
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-12-10
Completion:
2023-12-31
Conditions
Cow Milk Allergy
Interventions
DIETARY_SUPPLEMENT
No Results Yet
60
Participants
High Flow Nasal Cannula in Patients Undergoing ERCP Retrograde Cholangiopancreatography With Intravenous Sedation.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-08-25
Completion:
2025-03-17
Conditions
High-flow Nasal Cannula
Intravenous Sedation
Interventions
DEVICE
No Results Yet
420
Participants
Fragility Fractures of the Pelvis (FFP)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2022-03-01
Completion:
2026-06-30
Conditions
Pelvic Fracture
No Results Yet
45
Participants
A Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-12-12
Completion:
2023-12-20
Conditions
Neoplasms
Melanoma
Interventions
DRUG
40
Participants
980nm Diode Laser in the Treatment of Periodontal Disease in Cardiac Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-08-12
Completion:
2024-12-30
Conditions
Myocardial Infarction
Periodontal Diseases
Interventions
DEVICE
No Results Yet
166
Participants
Evaluation of Ultra-portable Ultrasound in General Practice
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-12-03
Completion:
2021-10-20
Conditions
Pneumonia
Pleural Effusion
Renal Colic
Hepatic Colic or Cholecystitis
Subcutaneous Abscess or Cyst
Fracture of Long Bones
Intra-uterine Pregnancy or Extra-uterine Pregnancy or Miscarriage
Phlebitis
Interventions
DIAGNOSTIC_TEST
No Results Yet
124
Participants
Cyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental Approach
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-15
Completion:
2024-08-01
Conditions
Suicidal Ideation
Interventions
DRUG
300
Participants
Band Versus Ring for Tricuspid Regurgitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-01-01
Completion:
2025-12-31
Conditions
Tricuspid Regurgitation
Interventions
PROCEDURE
No Results Yet
173
Participants
SCIB1 and iSCIB1+ in Melanoma Patients Receiving Nivolumab With Ipilimumab or SCIB1 With Pembrolizumab (The SCOPE Study)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-08-19
Completion:
2027-01-31
Conditions
Malignant Melanoma
Melanoma (Skin)
Melanoma Stage III
Melanoma Stage IV
Interventions
BIOLOGICAL
No Results Yet
9
Participants
A Study in Leukemia Patients With Karonudib
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-12-03
Completion:
2026-12-30
Conditions
Leukemia
Interventions
DRUG
No Results Yet
100
Participants
Pinnacle RSA Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-12-03
Completion:
2023-06-12
Conditions
Osteoarthritis
Degenerative Arthritis
Interventions
DEVICE
56
Participants
Individualized Physical Activity and Carotid Plaque Instability
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-12-03
Completion:
2022-09-12
Conditions
Carotid Atherosclerosis
Interventions
DEVICE
OTHER
BIOLOGICAL
No Results Yet
64
Participants
RAdium-223 and SABR Versus SABR for Oligometastatic Prostate Cancers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-08-09
Completion:
2025-07-15
Conditions
Prostate Cancer
Interventions
DRUG
RADIATION
0
Participants
Leveraging Mindsets to Improve Health and Wellbeing in Patients With Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-05-05
Completion:
2026-12-31
Conditions
Cancer
Interventions
OTHER
No Results Yet
33
Participants
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-12-19
Completion:
2025-05-27
Conditions
Multiple Sclerosis
Interventions
DRUG
No Results Yet
603
Participants
Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-09-16
Completion:
2025-06-19
Conditions
Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury
Interventions
DRUG
No Results Yet
14
Participants
Study of ME-401 in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2019-04-29
Completion:
2025-01-15
Conditions
Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma
Interventions
DRUG
No Results Yet
0
Participants
Telemedicine Notifications With Machine Learning for Postoperative Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-07-01
Completion:
2028-07-01
Conditions
Surgery--Complications
Perioperative/Postoperative Complications
Acute Kidney Injury
Hospital Mortality
Interventions
DEVICE
No Results Yet
Showing 40 trials per page