Clinical Trials
Showing trials with last updates posted in 2025.
126
Participants
Iris Vascular Area Density-Based Preoperative Pain-Risk Screening and Intervention in Second-Eye Cataract Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-02-23
Completion:
2025-11-20
Conditions
Age Related Cataract
Pain Management During Cataract Surgery
Interventions
DRUG
No Results Yet
50
Participants
Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2024-07-19
Completion:
2029-12-31
Conditions
Cholangiocarcinoma
Interventions
DRUG
No Results Yet
40
Participants
A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TQB3217 Tablets in Subjects With Advanced Malignant Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2026-12-31
Conditions
Advanced Cancer
Interventions
DRUG
No Results Yet
20
Participants
A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2029-01-01
Conditions
Ischemic Stroke
Interventions
OTHER
No Results Yet
30
Participants
A Mindfulness-Based Stress Reduction Program for Improving Mental Health Outcomes for Underserved Cancer Patients in Minnesota
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-11-05
Completion:
2027-11-15
Conditions
Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm
Interventions
OTHER
BEHAVIORAL
No Results Yet
12
Participants
Treatment of Locally Recurrent Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-05-31
Completion:
2028-05-31
Conditions
Prostate Cancer
Recurrent Prostate Cancer
Locally Recurrent Prostate Cancer
Interventions
DEVICE
No Results Yet
618
Participants
Compliance to Cervical Cancer Chemoradiation Guidelines: A Multicentric Implementation Audit and Resource Assessment Initiative of National Cancer Grid of India
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2021-02-01
Completion:
2026-03-31
Conditions
Cervical Cancer Screening
Gynecologic Cancers
Treatment Compliance
Chemoradiotherapy
Interventions
OTHER
No Results Yet
55
Participants
Indoor Daylight Photodynamic Therapy is an Effective, First-line Treatment for AK, But Its Feasibility is Limited by the Time Required for the Illumination (2 Hours). Our Objective Was to Evaluate the Efficacy of Idl-PDT With an Illumination Time of 1 Hour Versus 2 Hours in the Treatment of Scalp AK
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-01-02
Completion:
2025-07-01
Conditions
Actinic Keratosis (AK)
Interventions
OTHER
No Results Yet
100
Participants
Repeated Mesenchymal Stem Cell Therapy for Radiation-Induced Hyposalivation and Xerostomia in Head and Neck Cancer Survivors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2027-06-30
Conditions
Xerostomia Due to Hyposecretion of Salivary Gland
Xerostomia Due to Radiotherapy
Sjögren´s Syndrome
Interventions
DRUG
No Results Yet
14
Participants
Oral Food Processing for Digitally Constructed Complete Dentures Versus Conventional Complete Dentures.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-11-17
Completion:
2025-10-06
Conditions
Swallowing Disorder
Interventions
PROCEDURE
No Results Yet
60
Participants
Sensorimotor Integration in Patients With Tourette Syndrome
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-03-20
Completion:
2025-12-03
Conditions
Tourette Disorder
Sensory Gating
No Results Yet
92
Participants
Effectiveness of Home-Based Cardiac Rehabilitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-15
Completion:
2026-01-01
Conditions
Cardiac Rehabilitation
Interventions
BEHAVIORAL
No Results Yet
80
Participants
Pembrolizumab Plus Lenvatinib in Vulvar Cancer Patients: MITO VULVA-01
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2031-10-31
Conditions
Vulva Cancer
Interventions
DRUG
No Results Yet
158
Participants
Diactive-1: Scaled-up Personalized mHealth Program for Youth With Type 1 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2026-12-31
Conditions
Type 1 Diabetes (T1D)
Interventions
DEVICE
No Results Yet
5
Participants
A Study to Evaluate the Safety and Efficacy of Icatibant in Patients With Bradykinin Induced Angioedema
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-09-27
Completion:
2025-05-27
Conditions
Bradykinin-mediated Angioedema
Hereditary Angioedema (HAE)
Interventions
DRUG
No Results Yet
20
Participants
The Effects of Dietary Nitrate in Patients With Hypertensive Kidney Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-08
Completion:
2028-01-01
Conditions
Hypertension
CKD - Chronic Kidney Disease
Interventions
DIETARY_SUPPLEMENT
No Results Yet
52
Participants
Conformity of Conjunctival Hyperemia Assessment in Soft Contact Lens Wearers Using Image J Analysis and Efron Degree System
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-03-28
Completion:
2025-01-28
Conditions
Soft Contact Lenses
Interventions
DEVICE
No Results Yet
270
Participants
Effect of Non-invasive Neuromodulation on the Quality of Intestinal Cleansing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2027-03-21
Conditions
Intestinal Polyps
Interventions
OTHER
No Results Yet
90
Participants
A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-15
Completion:
2027-12-31
Conditions
Malocclusion
Interventions
DEVICE
No Results Yet
120
Participants
VEL-101 to Prevent Rejection After Kidney Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-07-31
Completion:
2028-10-31
Conditions
Transplantation, Kidney
Interventions
DRUG
No Results Yet
729
Participants
Survival Analysis of Surgical Resection Versus Observation in Patients With Initially uHCC Achieving CR After Systemic Therapy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-01
Completion:
2026-03-01
Conditions
Hepatocellular Carcinoma
Interventions
PROCEDURE
No Results Yet
20
Participants
Transcranial Magnetic Stimulation (TMS) for Negative Symptoms in Schizophrenia Spectrum Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-29
Completion:
2030-11-30
Conditions
Schizophrenia Spectrum Disorder
Interventions
DEVICE
No Results Yet
40
Participants
Cross-cultural Adaptation and Translation Validation of the iADH Universal Case Mix Tool (UCMT).
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-01
Completion:
2025-11-01
Conditions
Dentistry
No Results Yet
5000
Participants
Post-Intensive Care Syndrome - Multicentre Prospective Registry Database of the DACH Region
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2030-11-01
Conditions
PICS
PICS-F
No Results Yet
2442
Participants
Intensive Cholesterol-Lowering Within 24 Hours of PCI Perioperative Period
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2027-08-30
Conditions
STEMI - ST Elevation Myocardial Infarction
NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)
Interventions
DRUG
No Results Yet
33
Participants
Evaluation of the Effectiveness and Safety of Transcranial Direct Current Stimulation in Combination With Nasal Near Infrared Stimulation to Improve Cognitive Functions and Quality of Life in Elderly People With Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD).
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-01-01
Completion:
2024-04-30
Conditions
Alzheimer Disease
Mild Cognitive Impairment
Interventions
DEVICE
No Results Yet
66
Participants
Graded Motor Imagery and Task-Oriented Exercise in Shoulder Impingement
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-01
Completion:
2026-12-30
Conditions
Shoulder Impingement Syndrome
Pain
Motor Imagery Training
Task Oriented Training
Interventions
OTHER
No Results Yet
270
Participants
Prospective Validation of an Artificial Intelligence Tool for Pre-Anesthetic Assessment
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2026-03-01
Completion:
2027-06-30
Conditions
Preoperative Care
Interventions
OTHER
No Results Yet
30
Participants
Toripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-02-28
Completion:
2030-02-28
Conditions
Oropharyngeal Cancer
Interventions
DRUG
No Results Yet
59
Participants
DOACT Algorithm Versus AI-Based Decision Models in Oral Anticoagulant Therapy for Vascular Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-01-20
Completion:
2025-10-10
Conditions
Deep Vein Thrombosis
Superficial Thrombophlebitis
Pulmonary Thromboembolisms
Clinical Decision Support Systems
Artificial Intelligence
Interventions
OTHER
No Results Yet
38
Participants
Phrenic Infiltration as Cryoanalgesia Adjuvant for Early Postoperative Pain Following the Nuss Procedure
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2023-09-14
Completion:
2025-09-30
Conditions
Pectus Excavatum
Cryo Analgesia
Phrenic Nerve-related Diaphragmatic Impairment
No Results Yet
160
Participants
Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-03
Completion:
2027-06-30
Conditions
Plaque Psoriasis
Interventions
DRUG
OTHER
No Results Yet
578
Participants
Web-Based Toolkit to Improve Cancer-Related Emotional Distress and Anxiety in Rural Older Cancer Survivors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-08-26
Completion:
2031-08-26
Conditions
Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm
Interventions
OTHER
BEHAVIORAL
No Results Yet
80
Participants
24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-06-30
Completion:
2028-12-31
Conditions
Retinitis Pigmentosa (RP)
Usher Syndrome
Interventions
DRUG
OTHER
No Results Yet
68
Participants
Gradual Versus Intermittent Release of Tourniquet Effect on MAP in Hypertensive Patients Undergoing Upper Limb Orthopedic Surgeries
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-13
Completion:
2026-05-31
Conditions
Hemodynamics
Interventions
DEVICE
No Results Yet
854
Participants
Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-06-19
Completion:
2029-05-10
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
10000
Participants
Encourage Older Adults to Designate a Health Care Proxy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2027-01-31
Conditions
Designating a Healthcare Proxy
Interventions
BEHAVIORAL
No Results Yet
56
Participants
Pain Perception and Exercise-Induced Hypoalgesia Across Circadian Rhythms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2026-03-31
Conditions
Exercise Induced Hypoalgesia
Circadian Rhythm
Pain Perception
Healthy Participants
Chronotype
Physical Therapy
Interventions
BEHAVIORAL
No Results Yet
756
Participants
Improving Maternal and Child Health Through Point-of-care STI Testing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-05-31
Completion:
2029-06-30
Conditions
Treponema Pallidum Infection
Chlamydia Trachomatis Infection
Neisseria Gonorrheae Infection
Trichomonas Vaginalis Vaginitis
Sexually Transmitted Infection
Interventions
DIAGNOSTIC_TEST
No Results Yet
40
Participants
Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-03-31
Completion:
2028-12-31
Conditions
Rosacea
Vascular Diseases
Port-Wine Stain
Interventions
DEVICE
No Results Yet
Showing 40 trials per page