Clinical Trials
Showing trials with last updates posted in 2025.
270
Participants
Effect of Non-invasive Neuromodulation on the Quality of Intestinal Cleansing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2027-03-21
Conditions
Intestinal Polyps
Interventions
OTHER
No Results Yet
1000
Participants
This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-11-17
Completion:
2034-01-30
Conditions
Atopic Dermatitis
No Results Yet
90
Participants
A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-15
Completion:
2027-12-31
Conditions
Malocclusion
Interventions
DEVICE
No Results Yet
120
Participants
VEL-101 to Prevent Rejection After Kidney Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-07-31
Completion:
2028-10-31
Conditions
Transplantation, Kidney
Interventions
DRUG
No Results Yet
729
Participants
Survival Analysis of Surgical Resection Versus Observation in Patients With Initially uHCC Achieving CR After Systemic Therapy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-01
Completion:
2026-03-01
Conditions
Hepatocellular Carcinoma
Interventions
PROCEDURE
No Results Yet
20
Participants
Transcranial Magnetic Stimulation (TMS) for Negative Symptoms in Schizophrenia Spectrum Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-29
Completion:
2030-11-30
Conditions
Schizophrenia Spectrum Disorder
Interventions
DEVICE
No Results Yet
40
Participants
Cross-cultural Adaptation and Translation Validation of the iADH Universal Case Mix Tool (UCMT).
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-01
Completion:
2025-11-01
Conditions
Dentistry
No Results Yet
5000
Participants
Post-Intensive Care Syndrome - Multicentre Prospective Registry Database of the DACH Region
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2030-11-01
Conditions
PICS
PICS-F
No Results Yet
2442
Participants
Intensive Cholesterol-Lowering Within 24 Hours of PCI Perioperative Period
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2027-08-30
Conditions
STEMI - ST Elevation Myocardial Infarction
NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)
Interventions
DRUG
No Results Yet
33
Participants
Evaluation of the Effectiveness and Safety of Transcranial Direct Current Stimulation in Combination With Nasal Near Infrared Stimulation to Improve Cognitive Functions and Quality of Life in Elderly People With Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD).
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-01-01
Completion:
2024-04-30
Conditions
Alzheimer Disease
Mild Cognitive Impairment
Interventions
DEVICE
No Results Yet
66
Participants
Graded Motor Imagery and Task-Oriented Exercise in Shoulder Impingement
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-01
Completion:
2026-12-30
Conditions
Shoulder Impingement Syndrome
Pain
Motor Imagery Training
Task Oriented Training
Interventions
OTHER
No Results Yet
270
Participants
Prospective Validation of an Artificial Intelligence Tool for Pre-Anesthetic Assessment
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2026-03-01
Completion:
2027-06-30
Conditions
Preoperative Care
Interventions
OTHER
No Results Yet
30
Participants
Toripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-02-28
Completion:
2030-02-28
Conditions
Oropharyngeal Cancer
Interventions
DRUG
No Results Yet
59
Participants
DOACT Algorithm Versus AI-Based Decision Models in Oral Anticoagulant Therapy for Vascular Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-01-20
Completion:
2025-10-10
Conditions
Deep Vein Thrombosis
Superficial Thrombophlebitis
Pulmonary Thromboembolisms
Clinical Decision Support Systems
Artificial Intelligence
Interventions
OTHER
No Results Yet
38
Participants
Phrenic Infiltration as Cryoanalgesia Adjuvant for Early Postoperative Pain Following the Nuss Procedure
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2023-09-14
Completion:
2025-09-30
Conditions
Pectus Excavatum
Cryo Analgesia
Phrenic Nerve-related Diaphragmatic Impairment
No Results Yet
160
Participants
Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-03
Completion:
2027-06-30
Conditions
Plaque Psoriasis
Interventions
DRUG
OTHER
No Results Yet
578
Participants
Web-Based Toolkit to Improve Cancer-Related Emotional Distress and Anxiety in Rural Older Cancer Survivors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-08-26
Completion:
2031-08-26
Conditions
Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm
Interventions
OTHER
BEHAVIORAL
No Results Yet
80
Participants
24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-06-30
Completion:
2028-12-31
Conditions
Retinitis Pigmentosa (RP)
Usher Syndrome
Interventions
DRUG
OTHER
No Results Yet
68
Participants
Gradual Versus Intermittent Release of Tourniquet Effect on MAP in Hypertensive Patients Undergoing Upper Limb Orthopedic Surgeries
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-13
Completion:
2026-05-31
Conditions
Hemodynamics
Interventions
DEVICE
No Results Yet
854
Participants
Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-06-19
Completion:
2029-05-10
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
10000
Participants
Encourage Older Adults to Designate a Health Care Proxy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2027-01-31
Conditions
Designating a Healthcare Proxy
Interventions
BEHAVIORAL
No Results Yet
56
Participants
Pain Perception and Exercise-Induced Hypoalgesia Across Circadian Rhythms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2026-03-31
Conditions
Exercise Induced Hypoalgesia
Circadian Rhythm
Pain Perception
Healthy Participants
Chronotype
Physical Therapy
Interventions
BEHAVIORAL
No Results Yet
756
Participants
Improving Maternal and Child Health Through Point-of-care STI Testing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-05-31
Completion:
2029-06-30
Conditions
Treponema Pallidum Infection
Chlamydia Trachomatis Infection
Neisseria Gonorrheae Infection
Trichomonas Vaginalis Vaginitis
Sexually Transmitted Infection
Interventions
DIAGNOSTIC_TEST
No Results Yet
40
Participants
Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-03-31
Completion:
2028-12-31
Conditions
Rosacea
Vascular Diseases
Port-Wine Stain
Interventions
DEVICE
No Results Yet
78
Participants
Photobiomodulation for the Prevention of Oral Mucositis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-01
Completion:
2026-12-31
Conditions
Oral Mucositis
Interventions
DEVICE
No Results Yet
36
Participants
Effect of Moderate Alcohol on Absorption and Onset of Hezkue Sildenafil Suspension
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-04-15
Completion:
2026-06-15
Conditions
Erectile Dysfunction
Interventions
DRUG
OTHER
No Results Yet
64
Participants
Tele-Savvy for Latino Caregivers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-30
Completion:
2026-12-21
Conditions
Alzheimer Disease
Dementia
Caregiver Stress
Interventions
BEHAVIORAL
No Results Yet
45
Participants
Mckenzie Versus Maitland Cervical Mobilization Technique in Management of Non-specific Neck Pain.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-12
Completion:
2026-04-15
Conditions
Chronic Non-specific Neck Pain
Interventions
OTHER
No Results Yet
17587
Participants
Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-01
Completion:
2028-05-31
Conditions
Low Back Pain
Neck Pain
Interventions
BEHAVIORAL
No Results Yet
40
Participants
Effect of Dynamic Hand Splint on Hand ROM Post Extensor Tendon Repair
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-08-01
Completion:
2024-12-01
Conditions
Splints
Range of Motion
Extensor Tendons of Finger Anomalies
Interventions
OTHER
No Results Yet
100000
Participants
Optimizing Strategies to Maximize Patient Recruitment Yield
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2027-04-30
Conditions
Recruitment
Interventions
BEHAVIORAL
No Results Yet
8
Participants
Denture Retention of Intra-orally Scanned Versus Extra-orally Scanned Digitally Printed Maxillary Denture in Completely Edentulous Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-12-03
Completion:
2026-09-01
Conditions
Complete Edentulism
Interventions
DEVICE
No Results Yet
170
Participants
Real-world Use of Lutetium (177Lu) Vipivotide Tetraxetan in China(PSMAreal CN)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-22
Completion:
2029-08-31
Conditions
Metastatic Prostate Cancer
No Results Yet
100
Participants
Long-Term Low-Intervention SafEty and Clinical Outcomes Clinical Study of LivmArli® in Patients With Alagille Syndrome in the European Union (LEAP-EU)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-09-25
Completion:
2030-09-22
Conditions
Alagille Syndrome
Interventions
DRUG
No Results Yet
18
Participants
Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2027-05-31
Conditions
Open Angle Glaucoma (OAG)
NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)
Interventions
GENETIC
No Results Yet
56
Participants
Effects of Core Strengthening Exercises With Diapgragmatic Breathing Versus Core Strengthening Exercises With Pilate Breathing in Diabetes Type II Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-08-06
Completion:
2026-01-03
Conditions
Diabetes Type II
Interventions
OTHER
No Results Yet
15
Participants
Tridimensional Robotic Assessment of Neglect in Brain Injured Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2026-10-31
Conditions
Neglect
Brain Injured Patients
Stroke
Unilateral Spatial Neglect (USN)
Post-stroke Cognitive Impairment
Interventions
DEVICE
No Results Yet
60
Participants
Remimazolam NeuroImaging
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-03-01
Completion:
2027-12-01
Conditions
Anesthesia
Pain
Remimazolam
Interventions
DRUG
DEVICE
No Results Yet
110
Participants
This Study Compares Two Different Ways of Cleaning and Shaping Root Canals During Root-canal Treatment: the Step-down Technique and the Step-back Technique. Iu Want to Find Out Which Method Causes Less Pain After the Procedure. Patients Will be Randomly Placed Into One of the Two Groups, Treated Wit
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-02-01
Completion:
2026-08-01
Conditions
Pulp Necrosis
Interventions
PROCEDURE
No Results Yet
42
Participants
A Phase II Study to Evaluate the Efficacy and Safety of Anti-HER2 Triple-targeted Drugs Combined With CDK4/6 Inhibitors in Neoadjuvant Therapy for ER-positive HER2-positive Breast Cancer Patients.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2027-10-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
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