Clinical Trials

Showing trials with last updates posted in 2025.

NCT05074355 | RECRUITING | PHASE2
40 Participants

Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-11-08
Completion: 2026-12-31
Conditions
Myeloproliferative Neoplasm
Interventions
DRUG
No Results Yet
NCT05072483 | RECRUITING
155 Participants

Natural History Study of CADASIL

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2022-04-18
Completion: 2034-06-01
Conditions
Cardiovascular Disease Arterial Stiffness Germline Mutation in the NOTCH 3 Gene Pathogenesis of CADASIL Clinical Phenotype of CADASIL
Interventions
DEVICE
No Results Yet
NCT05064150 | ACTIVE_NOT_RECRUITING
2539 Participants

Neuroendocrine Tumors - Patient Reported Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2022-05-10
Completion: 2026-06-30
Conditions
Neuroendocrine Tumors Gastroenteropancreatic Neuroendocrine Tumor Lung Neuroendocrine Neoplasm Neuroendocrine Carcinoma
No Results Yet
NCT05055063 | RECRUITING | PHASE1
30 Participants

A Phase 1 With Extension Cohort, Single Arm, Single Center, Open Label Trial of Belantamab Mafodotin for the Treatment of High-Risk Smoldering Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-05-18
Completion: 2027-02-02
Conditions
Myeloma
Interventions
DRUG
No Results Yet
NCT05050539 | RECRUITING | NA
1850 Participants

Adaptive Implementation to Optimize Delivery of Obesity Prevention Practices in Early Care and Education Settings

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-06-14
Completion: 2026-06-30
Conditions
Obesity, Childhood Nutrition Aspect of Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05044676 | TERMINATED
4 Participants

Immune Cells as a New Biomarker of Response in Patients Treated by Immunotherapy for Advanced Hepatocellular Carcinoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2023-09-08
Completion: 2025-09-22
Conditions
Hepatocellular Carcinoma
Interventions
OTHER
No Results Yet
NCT05038228 | ACTIVE_NOT_RECRUITING
1 Participants

High Gastrointestinal Bleed Risk Outcomes in Patients With Non-valvular Atrial Fibrillation (NVAF) in France

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2022-08-01
Completion: 2026-04-08
Conditions
Atrial Fibrillation
Interventions
DRUG
No Results Yet
NCT05030506 | ACTIVE_NOT_RECRUITING | PHASE1
45 Participants

A Study of Belzutifan (MK-6482) as Monotherapy and in Combination With Lenvatinib (E7080/MK-7902) With or Without Pembrolizumab (MK-3475) in China Participants With Advanced Renal Cell Carcinoma (MK-6482-010)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-10-13
Completion: 2027-06-30
Conditions
Renal Cell Carcinoma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05026528 | TERMINATED | NA
138 Participants

Digital Diabetes Self Management Education and Support for Patients With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-11-30
Completion: 2025-04-30
Conditions
Type 2 Diabetes
Interventions
OTHER
No Results Yet
NCT05024513 | COMPLETED | PHASE2
127 Participants

Biliary Drainage Plus HAIC in Locally Advanced pCCA

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-11-01
Completion: 2025-10-20
Conditions
Perihilar Cholangiocarcinoma
Interventions
DRUG PROCEDURE OTHER
No Results Yet
NCT05020535 | RECRUITING | PHASE2
120 Participants

Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-10-10
Completion: 2026-11-30
Conditions
Intracerebral Hemorrhage
Interventions
DRUG OTHER
No Results Yet
NCT05007730 | COMPLETED | NA
10 Participants

Enhancing Health and Quality of Life for Individuals With Dementia Through Transitional-State Snacks

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-06-01
Completion: 2025-11-03
Conditions
Dementia Nutrition Poor
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT04992611 | COMPLETED | NA
190 Participants

Sleep Timing, Eating and Activity Measurement Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-07-16
Completion: 2025-07-26
Conditions
Sleep Circadian Rhythm Disorders Dietary Habits
Interventions
BEHAVIORAL
No Results Yet
NCT04974593 | RECRUITING | PHASE3
90 Participants

Predictive Value of Hydrogen/Methane Lactose Breath Testing on the Therapeutic Effect of Lactose-free Diet in Moderate to Severe ROME IV IBS.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-10-22
Completion: 2028-01-01
Conditions
Irritable Bowel Syndrome Lactose Intolerant
Interventions
OTHER
No Results Yet
NCT04966663 | RECRUITING | PHASE2
66 Participants

Using ctDNA to Determine Therapies for Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-03-28
Completion: 2026-08-01
Conditions
Non Small Cell Lung Cancer Complete Surgical Resection Circulating Tumor DNA
Interventions
DRUG PROCEDURE
No Results Yet
NCT04965090 | COMPLETED | PHASE2
43 Participants

A Study of Amivantamab and Lazertinib in People With Non-Small Cell Lung Cancer (NSCLC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-09-30
Completion: 2025-12-15
Conditions
Metastatic Non Small Cell Lung Cancer Recurrent Non Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT04950101 | COMPLETED | NA
304 Participants

Prevalence of Anal High-risk Human Papilloma Virus Infection and Abnormal Anal Cytology in Men Who Have Sex With Men Using Pre Exposure Prophylaxis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2020-10-20
Completion: 2023-05-04
Conditions
Human Papilloma Virus
Interventions
OTHER
No Results Yet
NCT04939402 | ACTIVE_NOT_RECRUITING | NA
200 Participants

SARS-COV-2 Seroprevalence and Seroconversion Among Employees of the UZ Brussel Following COVID-19 Vaccination Using an Adenoviral Vector

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-05-05
Completion: 2028-05-31
Conditions
SARS-CoV-2 Covid19
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04927377 | COMPLETED | NA
90 Participants

Accessible and Inclusive Diabetes Telecoaching Self-Management Program

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-10-31
Completion: 2025-09-30
Conditions
Diabete Type 2 Disability Physical
Interventions
BEHAVIORAL
No Results Yet
NCT04922411 | COMPLETED | NA
49 Participants

Cortical Network Modulation by Subthalamic Nucleus DBS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-04-23
Completion: 2025-04-01
Conditions
Parkinson Disease Deep Brain Stimulation
Interventions
DEVICE
No Results Yet
NCT04922333 | RECRUITING | PHASE3
200 Participants

Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-03-28
Completion: 2028-04-30
Conditions
Bone Loss
Interventions
DRUG
No Results Yet
NCT04913493 | TERMINATED | NA
22 Participants

Use of Sublingual Microcirculation and FloTrac Monitoring During Major Vascular Surgery and Its Effect on Hospital LOS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-06-08
Completion: 2023-04-01
Conditions
Carotid Artery Plaque Aortic Aneurysm Aneurysm
Interventions
PROCEDURE
No Results Yet
NCT04899102 | RECRUITING | NA
25 Participants

Intermittent Fasting for NAFLD in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-02-01
Completion: 2026-07-31
Conditions
Fatty Liver Intermittent Fasting Fatty Liver, Nonalcoholic Non-Alcoholic Fatty Liver Disease Liver Fat
Interventions
BEHAVIORAL
No Results Yet
NCT04868058 | TERMINATED | NA
28 Participants

Serratus Anterior or Erector Spinae Block for Hybrid Arrhythmia Ablation Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2020-10-02
Completion: 2021-05-11
Conditions
Arrhythmia
Interventions
DRUG
No Results Yet
NCT04863924 | ACTIVE_NOT_RECRUITING
170 Participants

Accelerating Lung Cancer Diagnosis Through Liquid Biopsy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2021-01-14
Completion: 2023-07-25
Conditions
Non-small Cell Lung Cancer
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04850599 | ACTIVE_NOT_RECRUITING | PHASE2
5 Participants

Isatuximab, Carfilzomib, and Pomalidomide for the Treatment of Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-06-14
Completion: 2026-10-15
Conditions
Recurrent Plasma Cell Myeloma Refractory Plasma Cell Myeloma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT04848116 | ACTIVE_NOT_RECRUITING | PHASE2
24 Participants

Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-04-24
Completion: 2026-04-30
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT04815005 | RECRUITING
1000 Participants

HoFH, the International Clinical Collaborators Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2017-01-24
Completion: 2026-12-31
Conditions
Homozygous Familial Hypercholesterolemia
Interventions
OTHER
No Results Yet
NCT04813328 | ACTIVE_NOT_RECRUITING
1500 Participants

The Effect of Helminth Infection Plus COVID-19 Infection on the Immune Response and Intestinal Microorganisms

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2021-06-01
Completion: 2026-04-30
Conditions
COVID-19
No Results Yet
NCT04800029 | COMPLETED | NA
32406 Participants

Telehealth to Improve Prevention of Suicide (TIPS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-07-12
Completion: 2025-11-30
Conditions
Suicide Risk
Interventions
OTHER
No Results Yet
NCT04789330 | COMPLETED | PHASE4
3626 Participants

Norepinephrine vs Phenylephrine During General Anesthesia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-07-01
Completion: 2022-04-01
Conditions
Anesthesia Surgery Hypotension
Interventions
DRUG
NCT04756791 | WITHDRAWN | PHASE4
0 Participants

Prospective Comparison of Single-Injection Serratus Anterior Plane Block With Ropivacaine Versus Local Infiltration of Anaesthetic After Breast Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-06-16
Completion: 2023-12-31
Conditions
Mastectomy; Lymphedema
Interventions
PROCEDURE
No Results Yet
NCT04747587 | COMPLETED | NA
53 Participants

Non-use After Stroke: Influence of Applied Force and Precision When Reaching With the Paretic Upper Limb

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-05-11
Completion: 2023-04-25
Conditions
Stroke
Interventions
OTHER
No Results Yet
NCT04745910 | ACTIVE_NOT_RECRUITING | PHASE4
10 Participants

Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-04-05
Completion: 2026-07-31
Conditions
Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm Tumor Lysis Syndrome
Interventions
DRUG
No Results Yet
NCT04740736 | COMPLETED | NA
106 Participants

Cardiovascular Analysis of PEM

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-08-31
Completion: 2025-07-11
Conditions
Myalgic Encephalomyelitis Chronic Fatigue Syndrome
Interventions
PROCEDURE
No Results Yet
NCT04729504 | RECRUITING | NA
2000 Participants

Cultural Adaptation of a SSI for Youth Anxiety

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-03-08
Completion: 2026-12-21
Conditions
Anxiety Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT04728230 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
63 Participants

Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-01-05
Completion: 2027-12-31
Conditions
Extensive Stage Lung Small Cell Carcinoma Stage IV Lung Cancer AJCC v8 Stage IVA Lung Cancer AJCC v8 Stage IVB Lung Cancer AJCC v8
Interventions
DRUG BIOLOGICAL RADIATION
No Results Yet
NCT04724668 | COMPLETED | NA
43 Participants

The Role of the Circadian System in Binge Eating Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-01-15
Completion: 2025-05-30
Conditions
Binge-Eating Disorder Circadian Rhythm Disorders
Interventions
DIETARY_SUPPLEMENT DEVICE
No Results Yet
NCT04697628 | ACTIVE_NOT_RECRUITING | PHASE3
502 Participants

Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2021-02-22
Completion: 2023-07-24
Conditions
Cervical Cancer
Interventions
DRUG
NCT04697368 | ACTIVE_NOT_RECRUITING | NA
70 Participants

The Efficacy of Upper Limb Rehabilitation With Exoskeleton in Patients With Subacute Stroke.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2020-12-28
Completion: 2025-03-01
Conditions
Stroke Upper Extremity Paresis
Interventions
DEVICE OTHER
No Results Yet
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