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Clinical Trials

Showing trials with last updates posted in 2025.

NCT03608956 | WITHDRAWN
0 Participants

Renal Oxygen Saturation and Its Association With Acute Renal Injury

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-05-01
Completion: 2019-03-31
Conditions
Acute Kidney Injury Children Cardiac Surgery
No Results Yet
NCT03598829 | COMPLETED
219 Participants

A Prospective Clinical Trial Comparing Serum Mast Cell Tryptase (SMCT) Levels to Arthrofibrosis Rates Among Primary Total Knee Arthroplasty (TKA) Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-07-01
Completion: 2023-11-15
Conditions
Knee Osteoarthritis Arthropathy of Knee Arthrofibrosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03573310 | COMPLETED | PHASE1
114 Participants

A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-07-13
Completion: 2025-09-25
Conditions
Neoplasms Solid Tumor, Adult Non-Hodgkin Lymphoma Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
NCT03568552 | COMPLETED | NA
7554 Participants

Patient Decision Aid for Opioid Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2020-08-03
Completion: 2024-08-31
Conditions
Opioid Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT03527719 | ACTIVE_NOT_RECRUITING | NA
33995 Participants

China Rural Hypertension Control Project

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-05-08
Completion: 2026-01-31
Conditions
Hypertension
Interventions
OTHER
No Results Yet
NCT03505801 | ACTIVE_NOT_RECRUITING
1826 Participants

Confirm Rx Insertable Cardiac Monitor SMART Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-04-24
Completion: 2019-09-19
Conditions
Cardiac Arrhythmias Symptoms and Signs Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT03501589 | ENROLLING_BY_INVITATION
100 Participants

Molecular Modulation of the Growth Plate

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2013-10-31
Completion: 2026-10-31
Conditions
Growth Plate Injury
No Results Yet
NCT03495232 | ACTIVE_NOT_RECRUITING
700 Participants

Persona Cohort Nordic Multicenter Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2016-11-01
Completion: 2029-04-07
Conditions
Knee Arthropathy
Interventions
DEVICE
No Results Yet
NCT03492177 | ACTIVE_NOT_RECRUITING | PHASE2
63 Participants

A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-07-23
Completion: 2022-03-28
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
Results Available
NCT03478514 | ACTIVE_NOT_RECRUITING | PHASE2
39 Participants

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-09-11
Completion: 2026-03-30
Conditions
Mantle Cell Lymphoma B Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT03466788 | COMPLETED | NA
51 Participants

Impact of Adjuvant Chemotherapy on the Quality of Life of Patients Treated for Stage II / III Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-03-29
Completion: 2019-03-28
Conditions
Endometrial Cancer Chemotherapy Effect Quality of Life
Interventions
OTHER
Results Available
NCT03434392 | RECRUITING | NA
500 Participants

QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-10-24
Completion: 2026-06-30
Conditions
Chronic Pancreatitis Chronic Pain
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03407833 | ENROLLING_BY_INVITATION
500 Participants

Physiologic and Functional Adaptations of Insulin Sensitive Tissues

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-02-13
Completion: 2028-02-29
Conditions
Diabetes Insulin Resistance Obesity Bariatric Surgery Candidate Roux-en-y Gastric Bypass Liver Diseases
Interventions
OTHER
No Results Yet
NCT03391479 | ACTIVE_NOT_RECRUITING | PHASE2
25 Participants

A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-08-15
Completion: 2026-12-31
Conditions
Penile Cancer Advanced Cancer Metastatic Cancer
Interventions
DRUG OTHER
No Results Yet
NCT03388632 | COMPLETED | PHASE1
31 Participants

Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-02-05
Completion: 2024-11-27
Conditions
Metastatic Solid Tumors Treatment-Refractory Cancers
Interventions
DRUG PROCEDURE DIAGNOSTIC_TEST
Results Available
NCT03328130 | TERMINATED | PHASE1/PHASE2
19 Participants

Safety and Efficacy Study in Patients With Retinitis Pigmentosa Due to Mutations in PDE6B Gene

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-11-06
Completion: 2025-06-30
Conditions
Retinitis Pigmentosa
Interventions
BIOLOGICAL
No Results Yet
NCT03253692 | COMPLETED
36 Participants

Prospective Multicenter Registry On Radiation Dose Estimates Of Cardiac CT Angiography in Daily Practice in 2017 (PROTECTION VI)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2017-10-03
Completion: 2018-06-30
Conditions
Arteriosclerosis Coronary Artery Disease Coronary Disease Myocardial Ischemia Arterial Occlusive Diseases
No Results Yet
NCT03245593 | ACTIVE_NOT_RECRUITING | NA
300 Participants

Shared Medical Decision Making in the Prophylactic Treatment of Bipolar Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-04-24
Completion: 2025-12-31
Conditions
Bipolar Disorder
Interventions
OTHER
No Results Yet
NCT03190928 | RECRUITING
200 Participants

Clonal Evolution in Follicular Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2017-07-27
Completion: 2029-01-01
Conditions
Follicular Lymphoma
No Results Yet
NCT03172624 | COMPLETED | PHASE2
64 Participants

Study of Nivolumab Plus Ipilimumab in Patients With Salivary Gland Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-05-26
Completion: 2024-12-18
Conditions
Salivary Gland Cancer
Interventions
DRUG
Results Available
NCT03152669 | RECRUITING
3500 Participants

The Extended Salford Lung Study ("Ex-SLS") Data Access Project

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-04-15
Completion: 2028-04-30
Conditions
Asthma
No Results Yet
NCT03142841 | COMPLETED | NA
210 Participants

Spanish Intervention for Caregivers of Veterans With Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-01-01
Completion: 2024-03-04
Conditions
Depression
Interventions
OTHER
Results Available
NCT03079999 | ACTIVE_NOT_RECRUITING | PHASE2
97 Participants

Study of Aspirin in Patients With Vestibular Schwannoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-06-11
Completion: 2026-08-31
Conditions
Vestibular Schwannoma Acoustic Neuroma Neurofibromatosis 2
Interventions
DRUG
No Results Yet
NCT03069469 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
120 Participants

Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-02-16
Completion: 2026-07-31
Conditions
Advanced Malignant Neoplasm Pigmented Villonodular Synovitis Giant Cell Tumor of Tendon Sheath Tenosynovial Giant Cell Tumor Tenosynovial Giant Cell Tumor, Diffuse
Interventions
DRUG
No Results Yet
NCT03009981 | COMPLETED | PHASE3
504 Participants

A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-03-06
Completion: 2025-06-25
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT03006172 | ACTIVE_NOT_RECRUITING | PHASE1
200 Participants

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-12-13
Completion: 2026-12-31
Conditions
Breast Cancer Solid Tumor
Interventions
DRUG
No Results Yet
NCT02993900 | RECRUITING | NA
54 Participants

Image-Guided Gynecologic Brachytherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-12-15
Completion: 2026-12-31
Conditions
Cervical Cancer Uterine Cancer Vaginal Cancer Vulvar Cancer Bladder Cancer
Interventions
DEVICE
No Results Yet
NCT02971501 | ACTIVE_NOT_RECRUITING | PHASE2
7 Participants

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-06-27
Completion: 2025-02-18
Conditions
Metastatic Lung Non-Small Cell Carcinoma Metastatic Malignant Neoplasm in the Brain Stage IV Lung Cancer AJCC v8
Interventions
DRUG BIOLOGICAL PROCEDURE
No Results Yet
NCT02918344 | COMPLETED
196 Participants

Complications From the Use of Calcium Phosphate Paste in Mandibular Lengthening Osteotomies

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2017-03-01
Completion: 2019-12-31
Conditions
Jaw Anomalies Infection
Interventions
OTHER PROCEDURE
No Results Yet
NCT02900183 | WITHDRAWN | PHASE2
0 Participants

Safety, Tolerability and Effect of ARC-AAT Injection on Circulating and Intrahepatic Alpha-1 Antitrypsin Levels

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-10-31
Completion: 2016-11-30
Conditions
Alpha-1 Antitrypsin Deficiency
Interventions
DRUG
No Results Yet
NCT02891954 | ACTIVE_NOT_RECRUITING | PHASE1
700 Participants

Genetics of Response to Canagliflozin

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-09-30
Completion: 2023-09-25
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT02835222 | RECRUITING | PHASE2
64 Participants

Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-02-02
Completion: 2026-03-31
Conditions
Untreated Adult Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT02821013 | RECRUITING | PHASE3
614 Participants

Duration of Anti-PD-1 Therapy in Metastatic Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-10-31
Completion: 2027-12-31
Conditions
Unresectable/Metastatic Melanoma
Interventions
DRUG
No Results Yet
NCT02819752 | TERMINATED | PHASE1
3 Participants

PEmbrolizumab Combined With Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-07-12
Completion: 2019-11-28
Conditions
Squamous Cell Carcinoma of the Head and Neck Squamous Cell Carcinoma
Interventions
DRUG RADIATION
Results Available
NCT02770066 | RECRUITING
160 Participants

A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2015-01-01
Completion: 2030-01-31
Conditions
Renal Artery Obstruction Hypertension, Renovascular Cardiovascular Diseases Kidney Diseases
Interventions
DEVICE
No Results Yet
NCT02726997 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
18 Participants

Matched Paired Pharmacodynamics and Feasibility Study of Durvalumab in Combination With Chemotherapy in Frontline Ovarian Cancer (N-Dur)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-07-06
Completion: 2027-12-31
Conditions
Stage III Fallopian Tube Cancer AJCC v7 Stage III Ovarian Cancer AJCC v6 and v7 Stage III Primary Peritoneal Cancer AJCC v7 Stage IIIA Fallopian Tube Cancer AJCC v7 Stage IIIA Ovarian Cancer AJCC v6 and v7 Stage IIIA Primary Peritoneal Cancer AJCC v7 Stage IIIB Fallopian Tube Cancer AJCC v7 Stage IIIB Ovarian Cancer AJCC v6 and v7 Stage IIIB Primary Peritoneal Cancer AJCC v7 Stage IIIC Fallopian Tube Cancer AJCC v7 Stage IIIC Ovarian Cancer AJCC v6 and v7 Stage IIIC Primary Peritoneal Cancer AJCC v7 Stage IV Fallopian Tube Cancer AJCC v6 and v7 Stage IV Ovarian Cancer AJCC v6 and v7 Stage IV Primary Peritoneal Cancer AJCC v7
Interventions
DRUG BIOLOGICAL OTHER
No Results Yet
NCT02696707 | COMPLETED | PHASE4
200 Participants

An Integrated Consent Model Study to Compare Two Standard of Care Schedules for Monitoring Cardiac Function in Patients Receiving Trastuzumab for Early Stage Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-06-30
Completion: 2020-05-31
Conditions
Breast Cancer
Interventions
PROCEDURE
Results Available
NCT02660645 | RECRUITING
4400 Participants

Blue Light Cystoscopy With Cysview® Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2014-04-30
Completion: 2028-12-31
Conditions
Bladder Cancer
Interventions
DRUG DEVICE
No Results Yet
NCT02611037 | COMPLETED | PHASE2
34 Participants

Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-03-04
Completion: 2021-10-16
Conditions
Malignant Pleural Mesothelioma Mesothelioma
Interventions
DRUG OTHER
Results Available
NCT02451891 | TERMINATED | PHASE1
38 Participants

A Phase I Study to Assess Ebola Vaccines cAd3-EBO Z and MVA-EBO Z

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2015-05-06
Completion: 2017-08-22
Conditions
Ebola Virus Disease
Interventions
BIOLOGICAL
No Results Yet
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