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Clinical Trials

Showing trials with last updates posted in 2025.

NCT05166850 | RECRUITING | NA
2900 Participants

Preventative Intervention for Cholera for 7 Days

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-12-22
Completion: 2026-12-22
Conditions
Cholera Water-Related Diseases Diarrhea Infectious
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT05166785 | ACTIVE_NOT_RECRUITING | NA
238 Participants

BRInging the Diabetes Prevention Program to GEriatric Populations

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-10-05
Completion: 2026-05-31
Conditions
Pre Diabetes
Interventions
OTHER
No Results Yet
NCT05161663 | COMPLETED | NA
98 Participants

Peer-driven Intervention on PrEP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-01-06
Completion: 2024-12-23
Conditions
HIV Infections
Interventions
BEHAVIORAL
No Results Yet
NCT05156281 | RECRUITING | PHASE3
800 Participants

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-12-13
Completion: 2026-04-30
Conditions
Relapsing Multiple Sclerosis
Interventions
DRUG
No Results Yet
NCT05152147 | ACTIVE_NOT_RECRUITING | PHASE3
920 Participants

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-12-02
Completion: 2026-07-31
Conditions
Gastric Neoplasms Gastroesophageal Adenocarcinoma Esophageal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT05149755 | ACTIVE_NOT_RECRUITING | NA
650 Participants

Evolut™ EXPAND TAVR II Pivotal Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-04-27
Completion: 2026-02-28
Conditions
Moderate Aortic Valve Stenosis
Interventions
DEVICE
No Results Yet
NCT05147220 | RECRUITING | PHASE3
800 Participants

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-12-16
Completion: 2026-04-30
Conditions
Relapsing Multiple Sclerosis
Interventions
DRUG
No Results Yet
NCT05145309 | NOT_YET_RECRUITING | PHASE2
45 Participants

Value of Potassium Magnesium Citrate in Preventing and Treating Hypertension in African Americans

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-11-15
Completion: 2031-12-01
Conditions
Hypertension
Interventions
DRUG
No Results Yet
NCT05144997 | ACTIVE_NOT_RECRUITING | PHASE4
76 Participants

Lorlatinib Continuation Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-12-28
Completion: 2026-12-28
Conditions
Non-Small-Cell Lung Cancer NSCLC
Interventions
DRUG
No Results Yet
NCT05134012 | RECRUITING | PHASE3
215 Participants

RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-05-08
Completion: 2026-04-30
Conditions
Coronary Artery Disease
Interventions
DRUG
No Results Yet
NCT05126758 | ACTIVE_NOT_RECRUITING | PHASE3
106 Participants

A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-06-22
Completion: 2025-06-18
Conditions
Muscular Dystrophies Muscular Dystrophy, Duchenne Muscular Disorders, Atrophic Muscular Diseases Neuromuscular Diseases Genetic Diseases, X-Linked Genetic Diseases, Inborn Nervous System Diseases
Interventions
BIOLOGICAL
No Results Yet
NCT05117255 | RECRUITING | NA
256 Participants

Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-01-04
Completion: 2027-03-01
Conditions
Generalized Anxiety Disorder Panic Disorder Social Anxiety Disorder Alcohol Use Disorder Depression
Interventions
BEHAVIORAL
No Results Yet
NCT05115110 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
259 Participants

A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-06-02
Completion: 2029-02-27
Conditions
Spinal Muscular Atrophy (SMA)
Interventions
DRUG
No Results Yet
NCT05114746 | RECRUITING | PHASE2
110 Participants

Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-01-25
Completion: 2023-12-08
Conditions
Prostate Cancer
Interventions
RADIATION OTHER
No Results Yet
NCT05114720 | COMPLETED | PHASE3
559 Participants

Moxifloxacin in Adjuvant Treatment of Patients With Operable Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-11-11
Completion: 2025-11-27
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT05084196 | RECRUITING | PHASE3
300 Participants

Melatonin for Prevention of Kidney Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-05
Completion: 2027-06-01
Conditions
Acute Kidney Injury Adverse Drug Event
Interventions
DRUG OTHER
No Results Yet
NCT05076175 | RECRUITING | PHASE2/PHASE3
120 Participants

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-05-30
Completion: 2026-05-22
Conditions
Colitis, Ulcerative
Interventions
DRUG
No Results Yet
NCT05074420 | TERMINATED | PHASE3
6 Participants

A Study of Baricitinib (LY3009104) in Children With COVID-19

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-12-21
Completion: 2024-09-05
Conditions
Covid19 Corona Virus Infection
Interventions
DRUG
No Results Yet
NCT05063331 | RECRUITING | NA
320 Participants

Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-12-15
Completion: 2030-07-31
Conditions
Uterine Prolapse
Interventions
PROCEDURE
No Results Yet
NCT05056376 | COMPLETED | NA
368 Participants

Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-10-01
Completion: 2024-12-16
Conditions
PreDiabetes Hyperglycemia Glucose, High Blood Overweight Prediabetic State Impaired Glucose Tolerance Obesity Weight Loss Lifestyle, Healthy Lifestyle Risk Reduction Lifestyle, Sedentary
Interventions
BEHAVIORAL
Results Available
NCT05026866 | ACTIVE_NOT_RECRUITING | PHASE3
2996 Participants

A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-08-27
Completion: 2027-11-30
Conditions
Alzheimer Disease
Interventions
DRUG
No Results Yet
NCT05020652 | ACTIVE_NOT_RECRUITING | PHASE2
107 Participants

A Clinical Trial of TQ05105 Tablets in the Treatment of Moderate and High Risk Myelofibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-11-11
Completion: 2023-10-15
Conditions
Moderate and High Risk Myelofibrosis
Interventions
DRUG
No Results Yet
NCT05013450 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
33 Participants

Dupilumab_Metastatic NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-09-10
Completion: 2025-09-10
Conditions
Metastatic Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05009992 | RECRUITING | PHASE2
360 Participants

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-10-20
Completion: 2027-12-31
Conditions
Diffuse Intrinsic Pontine Glioma Diffuse Midline Glioma, H3 K27M-Mutant Recurrent Diffuse Intrinsic Pontine Glioma Recurrent Diffuse Midline Glioma, H3 K27M-Mutant Recurrent WHO Grade III Glioma WHO Grade III Glioma
Interventions
DRUG RADIATION
No Results Yet
NCT05005442 | COMPLETED | PHASE2
192 Participants

A Study of Pembrolizumab/Vibostolimab (MK-7684A) in Relapsed/Refractory Hematological Malignancies (MK-7684A-004, KEYVIBE-004)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-09-28
Completion: 2024-12-10
Conditions
Hematological Malignancies
Interventions
BIOLOGICAL
Results Available
NCT05005026 | RECRUITING | NA
250 Participants

Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-11-23
Completion: 2026-09-30
Conditions
Spinal Cord Injuries Neuropathic Pain
Interventions
OTHER
No Results Yet
NCT05003843 | ACTIVE_NOT_RECRUITING | NA
229 Participants

BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-09-30
Completion: 2025-12-31
Conditions
Deep Vein Thrombosis DVT
Interventions
DEVICE
No Results Yet
NCT04992650 | ENROLLING_BY_INVITATION | NA
15 Participants

Ultrasonic Perfusion Imaging in Post-mastectomy Irradiated Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-03-01
Completion: 2026-08-15
Conditions
Breast Reconstruction Radiation Dermatitis Radiation Fibrosis Fat Grafting
Interventions
PROCEDURE
No Results Yet
NCT04991857 | ACTIVE_NOT_RECRUITING | NA
270 Participants

Technology-based Family-centered Empowerment Program for Heart Failure (T-FAME-HF)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-09-19
Completion: 2025-08-30
Conditions
Heart Failure Telerehabilitation Self Care Empowerment Disease Management
Interventions
OTHER
No Results Yet
NCT04986631 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
65 Participants

Pharmacokinetics and Pharmacodynamics of Topiramate for Weight Loss in Youth: PHARMATOP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-04-04
Completion: 2025-03-12
Conditions
Obesity, Childhood
Interventions
DRUG
No Results Yet
NCT04977986 | COMPLETED | PHASE3
215 Participants

Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-09-13
Completion: 2025-08-29
Conditions
Fragile X Syndrome
Interventions
DRUG
No Results Yet
NCT04975841 | COMPLETED | NA
9 Participants

Inclusion Body Myositis Treatment With Celution Processed Adipose Derived Regenerative Cells

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-03-10
Completion: 2025-09-26
Conditions
Inclusion Body Myositis
Interventions
DEVICE
No Results Yet
NCT04971889 | ACTIVE_NOT_RECRUITING | NA
291 Participants

Diabetes Medical Nutrition Therapy in Southeastern African American Women

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-08-03
Completion: 2025-10-31
Conditions
Type 2 Diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT04970810 | COMPLETED | NA
512 Participants

My Diabetes, My Community

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-07-29
Completion: 2024-10-31
Conditions
Type 2 Diabetes
Interventions
BEHAVIORAL
Results Available
NCT04969835 | RECRUITING | PHASE1
158 Participants

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-07-16
Completion: 2026-03-15
Conditions
Salivary Gland Tumor Urothelial Carcinoma Ovarian Carcinoma Breast Cancer Soft Tissue Sarcoma
Interventions
DRUG
No Results Yet
NCT04964895 | COMPLETED
50 Participants

Sexual Quality of Patients After Bladder Cancer Cystectomy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2021-09-20
Completion: 2022-09-01
Conditions
Sexual Dysfunction
Interventions
OTHER
No Results Yet
NCT04951856 | ACTIVE_NOT_RECRUITING | PHASE4
2166 Participants

Evolocumab or Normal Strategies to Reach LDL Objectives in Acute Myocardial Infarction Upbound to PCI

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-09-29
Completion: 2026-05-22
Conditions
STEMI - ST Elevation Myocardial Infarction NSTEMI - Non-ST Segment Elevation MI
Interventions
DRUG
No Results Yet
NCT04945317 | ENROLLING_BY_INVITATION | NA
349 Participants

ROSE for Improved Molecular Marker Testing Via EBUS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-05-14
Completion: 2026-12-31
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
OTHER
No Results Yet
NCT04938245 | RECRUITING
15 Participants

Improving Spinal Cord Stimulation With ECAPS

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2021-08-18
Completion: 2026-12-31
Conditions
Chronic Pain
Interventions
DEVICE
No Results Yet
NCT04910269 | RECRUITING | PHASE3
820 Participants

Outpatient Treatment With Anti-Coronavirus Immunoglobulin

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-08-06
Completion: 2026-08-01
Conditions
COVID SARS-CoV2 Infection Covid19
Interventions
BIOLOGICAL OTHER
No Results Yet
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