Clinical Trials

Showing trials with last updates posted in 2025.

NCT06471569 | RECRUITING | NA
26 Participants

Role of Aging and Individual Variation in Exercise Training Responsiveness

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-04-02
Completion: 2027-03-31
Conditions
Prediabetic State Cardiovascular Diseases Insulin Resistance Obesity
Interventions
BEHAVIORAL
No Results Yet
NCT06470451 | RECRUITING | PHASE3
80 Participants

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-01-07
Completion: 2026-07-31
Conditions
CTCL/ Mycosis Fungoides CTCL Mycosis Fungoides Cutaneous T Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT06470087 | COMPLETED | NA
28 Participants

High Purity Type I Collagen Based Skin Substitute Vs Dehydrated Human Amnion/Chorion Membrane in Treatment of DFUs

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-06-03
Completion: 2024-09-15
Conditions
Diabetic Foot Ulcer (DFU)
Interventions
DEVICE OTHER
NCT06466187 | RECRUITING | PHASE1
365 Participants

A Study of SGN-MesoC2 in Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-08-02
Completion: 2028-05-01
Conditions
Carcinoma, Non-Small-Cell Lung Ovarian Neoplasms Pancreatic Adenocarcinoma Colorectal Neoplasms Mesothelioma Other Solid Tumors Endometrial
Interventions
DRUG
No Results Yet
NCT06462183 | RECRUITING | PHASE1
105 Participants

Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-08-19
Completion: 2025-12-31
Conditions
Adenoid Cystic Carcinoma Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT06456411 | RECRUITING | NA
410 Participants

Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-07-12
Completion: 2030-07-12
Conditions
Breast Carcinoma Kidney Carcinoma Carcinoma
Interventions
PROCEDURE OTHER
No Results Yet
NCT06456190 | ACTIVE_NOT_RECRUITING | NA
50 Participants

Testing STAR and TexSTAR: A Video and Text Messaging Intervention

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-03-12
Completion: 2025-12-31
Conditions
Sexual Violence Posttraumatic Stress Disorder Opioid Use Opioid Misuse
Interventions
BEHAVIORAL
No Results Yet
NCT06452355 | RECRUITING | NA
72 Participants

Safety and Effectiveness of the KOKO Device to Treat Primary Abnormal Postpartum Uterine Bleeding or Hemorrhage

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-08-29
Completion: 2026-06-30
Conditions
Postpartum Hemorrhage Immediate Postpartum Hemorrhage Hemorrhage, Postpartum
Interventions
DEVICE
No Results Yet
NCT06442969 | RECRUITING | NA
60 Participants

Implementing an Intervention to Reduce Heat Stress and Chemical Exposures

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-06-07
Completion: 2026-01-31
Conditions
Dehydration Heat Stress
Interventions
OTHER
No Results Yet
NCT06441968 | COMPLETED | PHASE1
60 Participants

Safety and Immunogenicity Trial of MPV/S-2P SARS-CoV-2 Vaccine in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-07-01
Completion: 2025-11-12
Conditions
COVID-19
Interventions
BIOLOGICAL
No Results Yet
NCT06440967 | RECRUITING | PHASE3
540 Participants

A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-07-31
Completion: 2026-08-31
Conditions
Hot Flashes
Interventions
DRUG
No Results Yet
NCT06439082 | RECRUITING | PHASE3
315 Participants

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-10-24
Completion: 2029-03-23
Conditions
Sickle Cell Disease
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06430918 | ENROLLING_BY_INVITATION
150 Participants

Neuropathic Pain and it's Relation to Sleep Quality in Knee Osteoarthritis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2024-05-16
Completion: 2026-12-01
Conditions
Knee Osteoarthritis Sleep Disturbance Neuropathic Pain
Interventions
OTHER
No Results Yet
NCT06430801 | RECRUITING | PHASE3
1200 Participants

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-06-05
Completion: 2028-10-30
Conditions
Crohn's Disease
Interventions
DRUG OTHER
No Results Yet
NCT06423963 | RECRUITING | NA
26 Participants

Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-02-09
Completion: 2026-08-31
Conditions
Pancreatic Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06423950 | RECRUITING
35 Participants

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2024-05-01
Completion: 2027-04-30
Conditions
Pediatric Cancer
Interventions
OTHER
No Results Yet
NCT06421675 | RECRUITING | PHASE2
40 Participants

Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-03-28
Completion: 2026-12-31
Conditions
Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06418880 | COMPLETED | PHASE3
130 Participants

Automated Insulin Delivery for Inpatients With Dysglycemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-01-22
Completion: 2025-10-31
Conditions
Type 1 Diabetes Type 2 Diabetes
Interventions
DEVICE COMBINATION_PRODUCT
No Results Yet
NCT06410456 | COMPLETED | NA
54 Participants

The Effect of Schroth Exercises on Cerebral Cortical Thickness and Motor and Proprioceptive Fibres

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-04-01
Completion: 2024-12-30
Conditions
Adolescent Idiopathic Scoliosis
Interventions
OTHER
No Results Yet
NCT06410248 | RECRUITING | PHASE1
30 Participants

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-07-23
Completion: 2029-05-12
Conditions
Recurrent Glioblastoma, IDH-Wildtype Recurrent WHO Grade 2 Glioma Recurrent WHO Grade 3 Glioma Recurrent WHO Grade 4 Glioma
Interventions
DRUG PROCEDURE OTHER
No Results Yet
NCT06407934 | RECRUITING | PHASE3
1500 Participants

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-05-08
Completion: 2026-06-29
Conditions
Dermatitis Atopic
Interventions
DRUG
No Results Yet
NCT06404047 | COMPLETED | NA
660 Participants

RECOVER-ENERGIZE Platform Protocol

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-07-17
Completion: 2025-10-30
Conditions
Long COVID Long Covid19 Long Covid-19
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06400238 | ACTIVE_NOT_RECRUITING | PHASE2
35 Participants

Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Expression (MATCH - Subprotocol Z1H)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-10-15
Completion: 2023-01-27
Conditions
Advanced Lymphoma Advanced Malignant Solid Neoplasm Refractory Lymphoma Refractory Malignant Solid Neoplasm Refractory Multiple Myeloma
Interventions
PROCEDURE DRUG
NCT06397456 | RECRUITING | NA
180 Participants

Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-09-04
Completion: 2026-04-30
Conditions
Chronic Kidney Disease Hypertension
Interventions
BEHAVIORAL
No Results Yet
NCT06395103 | RECRUITING | PHASE1/PHASE2
90 Participants

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-08-16
Completion: 2029-03-31
Conditions
B-cell Acute Lymphoblastic Leukemia Diffuse Large B-cell Lymphoma Burkitt Lymphoma Neuroblastoma Ewing Sarcoma
Interventions
BIOLOGICAL
No Results Yet
NCT06378047 | ACTIVE_NOT_RECRUITING | PHASE1
2 Participants

Irreversible Electroporation & Pembro Immunotherapy in Locally Advanced Pancreatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-04-10
Completion: 2027-04-30
Conditions
Pancreatic Cancer Locally Advanced Pancreatic Cancer
Interventions
DRUG DEVICE
No Results Yet
NCT06376565 | RECRUITING | NA
1680 Participants

Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-11-08
Completion: 2027-11-30
Conditions
Colorectal Carcinoma
Interventions
OTHER
No Results Yet
NCT06374251 | COMPLETED | NA
8 Participants

Narrative Medicine for Improving Well-Being in Patients With Gastrointestinal Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-09-27
Completion: 2024-04-18
Conditions
Malignant Digestive System Neoplasm
Interventions
PROCEDURE OTHER
No Results Yet
NCT06369610 | RECRUITING | PHASE2
110 Participants

Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment of Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-04-22
Completion: 2027-04-22
Conditions
Oligometastatic Prostate Carcinoma Prostate Adenocarcinoma
Interventions
DRUG PROCEDURE BIOLOGICAL OTHER RADIATION
No Results Yet
NCT06362759 | ACTIVE_NOT_RECRUITING | PHASE2
143 Participants

A Study to Evaluate TOUR006 in Patients With Chronic Kidney Disease and Elevated Hs-CRP

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-05-15
Completion: 2025-03-06
Conditions
Chronic Kidney Diseases Chronic Kidney Insufficiency Chronic Renal Diseases Chronic Renal Insufficiency Kidney Insufficiency, Chronic C-Reactive Protein High Sensitivity C-Reactive Protein Hs-CRP hsCRP
Interventions
DRUG OTHER
No Results Yet
NCT06361147 | COMPLETED | NA
88 Participants

Psychoeducation of Adult Siblings of ASD People (Autism Spectrum Disorder).

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-03-28
Completion: 2024-10-30
Conditions
Autism Spectrum Disorder Sibling Relations
Interventions
OTHER
No Results Yet
NCT06345729 | RECRUITING | PHASE3
600 Participants

A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-05-24
Completion: 2029-02-19
Conditions
Non-small Cell Lung Cancer
Interventions
DRUG OTHER BIOLOGICAL
No Results Yet
NCT06337552 | RECRUITING | NA
54 Participants

High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-04-04
Completion: 2027-03-31
Conditions
Rectal Cancer Non-Small Cell Lung Cancer
Interventions
OTHER
No Results Yet
NCT06331728 | COMPLETED | PHASE1
32 Participants

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IGNX001

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-09-01
Completion: 2025-11-06
Conditions
Peanut Allergy
Interventions
DRUG
No Results Yet
NCT06323928 | ACTIVE_NOT_RECRUITING | PHASE2
874 Participants

A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-04-01
Completion: 2026-02-28
Conditions
Migraine
Interventions
DRUG
No Results Yet
NCT06323291 | COMPLETED | EARLY_PHASE1
20 Participants

Cancer Coaching and Remote Education for Self-Empowerment (CARES) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-04-01
Completion: 2025-05-26
Conditions
Pancreatic Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06321302 | RECRUITING | PHASE2
178 Participants

A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-05-15
Completion: 2027-04-30
Conditions
Diabetic Retinopathy
Interventions
DRUG
No Results Yet
NCT06312176 | RECRUITING | PHASE3
1200 Participants

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-04-14
Completion: 2027-07-11
Conditions
Breast Neoplasms
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT06309979 | RECRUITING
300 Participants

A Study to Assess Growth in Children With Idiopathic Short Stature

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2024-08-08
Completion: 2040-12-31
Conditions
Idiopathic Short Stature
No Results Yet
NCT06308419 | ACTIVE_NOT_RECRUITING | PHASE1
12 Participants

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-08-14
Completion: 2029-02-01
Conditions
Leiomyosarcoma Soft-tissue Sarcomas
Interventions
DRUG
No Results Yet
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