MedDataX Logo

Clinical Trials

Showing trials with last updates posted in 2025.

NCT05454488 | RECRUITING | PHASE2
30 Participants

An Evidence-Based Focal Cryotherapy Protocol for Focal Ablation of Intermediate Risk Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-07-25
Completion: 2026-01-31
Conditions
Prostate Cancer
Interventions
DRUG OTHER
No Results Yet
NCT05445843 | ACTIVE_NOT_RECRUITING | PHASE2
96 Participants

Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-12-06
Completion: 2024-11-04
Conditions
Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation
Interventions
DRUG
Results Available
NCT05427240 | RECRUITING | NA
1000 Participants

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-09-28
Completion: 2025-12-31
Conditions
Cancer
Interventions
OTHER
No Results Yet
NCT05410145 | RECRUITING | PHASE1/PHASE2
442 Participants

A Study of D3S-001 Monotherapy or Combination Therapy in Subjects With Advanced Solid Tumors With a KRAS p.G12C Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-08-03
Completion: 2027-04-30
Conditions
KRAS P.G12C
Interventions
DRUG
No Results Yet
NCT05405166 | ACTIVE_NOT_RECRUITING | PHASE3
531 Participants

SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-06-23
Completion: 2024-11-06
Conditions
Plasma Cell Myeloma Recurrent
Interventions
DRUG
Results Available
NCT05384990 | ACTIVE_NOT_RECRUITING | NA
36 Participants

Sensorimotor Control During Postural Transitions in CP

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-04-01
Completion: 2025-05-30
Conditions
Cerebral Palsy
Interventions
DEVICE
No Results Yet
NCT05371405 | RECRUITING
120 Participants

Machine Learning in Atrial Fibrillation

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2020-02-12
Completion: 2026-12-31
Conditions
Atrial Fibrillation Arrhythmias, Cardiac
No Results Yet
NCT05350267 | COMPLETED | NA
35 Participants

Changing Health and Lifestyle Behaviors of Offspring Following Maternal Bariatric Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-14
Completion: 2025-03-10
Conditions
Obesity, Childhood
Interventions
BEHAVIORAL
No Results Yet
NCT05342454 | RECRUITING
1720 Participants

A Comprehensive Clinical fMRI Software Solution to Enable Mapping of Critical Functional Networks and Cerebrovascular Reactivity in the Brain

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2022-05-23
Completion: 2026-11-30
Conditions
Brain Tumor
No Results Yet
NCT05325996 | COMPLETED | NA
53 Participants

Evaluating Home Testing Devices for the Management of Glaucoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-04-15
Completion: 2025-02-17
Conditions
Glaucoma, Open-Angle
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05317000 | RECRUITING | PHASE2
50 Participants

5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-03-23
Completion: 2028-06-30
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
DRUG
No Results Yet
NCT05309577 | COMPLETED | NA
21 Participants

Self-Care for Dementia Caregivers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-03-07
Completion: 2024-12-01
Conditions
Aging Mental Disorder Eating, Healthy Physical Inactivity Prodromal Symptoms Sleep Alzheimer Disease Dementia Circadian Rhythm Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT05278104 | COMPLETED | NA
63 Participants

A Study to Test Different Ways to Measure the Effect of Atomoxetine on Impulsive Behavior in Young Adults With Attention Deficit Hyperactivity Disorder (ADHD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-09-14
Completion: 2024-10-23
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
DRUG
Results Available
NCT05275478 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
192 Participants

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-23
Completion: 2025-12-31
Conditions
Locally Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT05248230 | RECRUITING | PHASE1/PHASE2
40 Participants

4D-710 in Adult Patients With Cystic Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-29
Completion: 2026-12-31
Conditions
Cystic Fibrosis Lung
Interventions
BIOLOGICAL
No Results Yet
NCT05229783 | COMPLETED | NA
110 Participants

High Resolution Virtual Chromoendoscopy Versus Seattle Protocol for the Surveillance of Barrett's Esophagus

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-05-11
Completion: 2024-12-03
Conditions
Barrett Esophagus
Interventions
PROCEDURE
No Results Yet
NCT05227053 | RECRUITING
200 Participants

STOP AF First Post-Approval Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2022-04-28
Completion: 2028-04-30
Conditions
Paroxysmal Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT05218499 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
400 Participants

Brightline-1: A Study to Compare Brigimadlin (BI 907828) With Doxorubicin in People With a Type of Cancer Called Dedifferentiated Liposarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-31
Completion: 2024-04-16
Conditions
Liposarcoma, Dedifferentiated
Interventions
DRUG
Results Available
NCT05217108 | RECRUITING | NA
200 Participants

A Mobile Phone Text-based Intervention to Reduce Sedentary Behavior and Engage Communities on the Importance of Healthy Lifestyles: the TEXT2MOVE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-01-05
Completion: 2026-10-31
Conditions
Life Style Healthy Lifestyle
Interventions
DEVICE
No Results Yet
NCT05206955 | RECRUITING | PHASE3
80 Participants

Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-09-16
Completion: 2026-11-30
Conditions
Fontan Palliation
Interventions
DRUG
No Results Yet
NCT05203835 | ACTIVE_NOT_RECRUITING | PHASE2
40 Participants

Trial of Acebilustat for the Treatment of Upper Arm Lymphedema

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-07-27
Completion: 2025-10-21
Conditions
Lymphedema of Upper Arm
Interventions
DRUG
No Results Yet
NCT05164172 | RECRUITING | PHASE3
600 Participants

A Study With Eptinezumab in Children and Adolescents (6 to 17 Years) With Chronic or Episodic Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-12-01
Completion: 2028-04-30
Conditions
Migraine
Interventions
DRUG
No Results Yet
NCT05153239 | ACTIVE_NOT_RECRUITING | PHASE3
705 Participants

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-07-22
Completion: 2026-04-30
Conditions
Relapsed Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05147142 | RECRUITING | NA
25 Participants

Low Intensity Focused Ultrasound: a New Paradigm for Depression and Anxiety

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-09-28
Completion: 2025-12-31
Conditions
Depression
Interventions
DEVICE
No Results Yet
NCT05127226 | RECRUITING | PHASE1/PHASE2
70 Participants

HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-12-22
Completion: 2029-03-31
Conditions
Angelman Syndrome
Interventions
DRUG
No Results Yet
NCT05115474 | RECRUITING
170 Participants

Study of Screening Brain MRIs in Stage IV Breast Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2021-12-21
Completion: 2026-04-17
Conditions
Triple Negative Breast Cancer HER2-positive Breast Cancer Hormone Receptor-positive Breast Cancer
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05110300 | TERMINATED | NA
114 Participants

A Multisite Exploration of Balance Perturbations With and Without Body Weight Support

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-12-15
Completion: 2023-11-06
Conditions
Stroke Stroke, Acute Balance; Distorted Balance; Impairment Gait, Unsteady
Interventions
DEVICE
Results Available
NCT05086393 | COMPLETED | PHASE4
241 Participants

Duloxetine RCT on Postop TKA Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-11-01
Completion: 2025-06-01
Conditions
Pain, Postoperative Total Knee Arthroplasty
Interventions
DRUG
No Results Yet
NCT05085457 | COMPLETED | NA
540 Participants

The Use of ExPreS in the Weaning of Patients in Invasive Mechanical Ventilation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-11-01
Completion: 2024-12-30
Conditions
Respiratory Insufficiency
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05083416 | COMPLETED | NA
29 Participants

Effect of Prolonged Nightly Fasting on Immunotherapy Outcomes in HNSCC - Role of Gut Microbiome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-10-20
Completion: 2023-03-31
Conditions
Head and Neck Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05078970 | RECRUITING | NA
306 Participants

Advancing Suicide Intervention Strategies for Teens During High Risk Periods

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-08-11
Completion: 2027-01-31
Conditions
Suicide Attempts Suicidal Ideation Suicide and Self-harm Suicide Threat
Interventions
BEHAVIORAL
No Results Yet
NCT05064878 | ACTIVE_NOT_RECRUITING | PHASE3
87 Participants

A Study to Investigate the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-08
Completion: 2027-11-08
Conditions
CDKL5 Deficiency Disorder Generalized Tonic Clonic Seizure Epileptic Spasm Refractory Seizures
Interventions
DRUG
No Results Yet
NCT05064423 | COMPLETED | NA
85 Participants

Clinical Trials Outreach & Education

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-06-15
Completion: 2022-03-23
Conditions
Knowledge, Attitudes, Practice
Interventions
BEHAVIORAL
No Results Yet
NCT05055830 | RECRUITING
2000 Participants

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2021-10-05
Completion: 2027-10-30
Conditions
Cardiac Disease Critically Ill Children, Adult
Interventions
DRUG
No Results Yet
NCT05045027 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
36 Participants

Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-09-01
Completion: 2026-09-10
Conditions
Glioma Malignant Glioma Recurrent Glioma Recurrent Malignant Glioma
Interventions
PROCEDURE
No Results Yet
NCT05044845 | COMPLETED
150 Participants

Needs Assessment of Knowledge, Beliefs, and Attitudes of Patients With Hemophilia B About Gene Therapy

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2022-01-18
Completion: 2025-10-14
Conditions
Gene Therapy Hemophilia B
Interventions
BEHAVIORAL
No Results Yet
NCT05040373 | RECRUITING
10 Participants

Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2020-08-01
Completion: 2030-10-12
Conditions
Hereditary Transthyretin-mediated (hATTR) Amyloidosis Polyneuropathy
No Results Yet
NCT05030038 | RECRUITING
25 Participants

Oral Aromatase Inhibitors Modify the Gut Microbiome

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-29
Completion: 2026-04-30
Conditions
Breast Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT05024929 | RECRUITING
32 Participants

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2021-07-16
Completion: 2031-02-01
Conditions
Papillary Thyroid Cancer Pediatric Cancer Differentiated Thyroid Cancer
Interventions
PROCEDURE
No Results Yet
NCT05015426 | ACTIVE_NOT_RECRUITING | PHASE1
20 Participants

Gamma Delta T-cell Infusion for AML at High Risk of Relapse After Allo HCT

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-21
Completion: 2025-08-30
Conditions
Acute Myeloid Leukemia
Interventions
BIOLOGICAL
No Results Yet
Previous
Sorted by latest updates
Next
Showing 40 trials per page · Total 108293 trials