Clinical Trials
Showing trials with last updates posted in 2025.
510
Participants
SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2023-02-10
Completion:
2030-08-30
Conditions
Oropharyngeal Cancer
Interventions
OTHER
RADIATION
No Results Yet
20
Participants
Pilot Study to Evaluate a Voice Journaling Application in Adolescents With Cystic Fibrosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-07-29
Completion:
2024-04-16
Conditions
Cystic Fibrosis
Interventions
OTHER
No Results Yet
62
Participants
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-06-10
Completion:
2026-06-10
Conditions
Lung Cancer
Lung Cancer Metastatic
Brain Metastases
Brain Metastases, Adult
Small-cell Lung Cancer
Small Cell Lung Carcinoma
Interventions
RADIATION
PROCEDURE
No Results Yet
40
Participants
A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2023-03-21
Completion:
2026-11-30
Conditions
T Cells
Colorectal Cancer
Lynch Syndrome
Interventions
DRUG
No Results Yet
229
Participants
Choosing Healthy Activities and Lifestyle Management Through Portal Support
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2023-02-24
Completion:
2026-12-31
Conditions
Weight Loss
Overweight and Obesity
Behavior, Health
Interventions
BEHAVIORAL
No Results Yet
129
Participants
Study of Anitocabtagene-autoleucel in Relapsed or Refractory Multiple Myeloma (iMMagine-1)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-07-15
Completion:
2026-12-31
Conditions
Multiple Myeloma
Interventions
BIOLOGICAL
No Results Yet
50
Participants
Onvansertib + Paclitaxel In TNBC
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-09-30
Completion:
2026-02-15
Conditions
Breast Cancer
Invasive Breast Cancer
Unresectable Breast Carcinoma
Locally Advanced Breast Cancer
Metastatic Breast Cancer
Inflammatory Breast Cancer
Triple Negative Breast Cancer (TNBC)
Hormone Receptor/Growth Factor Receptor-Negative Breast Cancer
HER2-negative Breast Cancer
Hormone Receptor Negative Breast Carcinoma
Interventions
DRUG
No Results Yet
35
Participants
Survey of Human Rabies Immune Globulin Safety in Children
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2023-02-22
Completion:
2025-09-17
Conditions
Rabies
Rabies Human
Rabies Virus Infection
Pediatrics
Interventions
BIOLOGICAL
No Results Yet
70
Participants
Renal Metabolism in Salt-sensitive Human Blood Pressure
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2021-11-01
Completion:
2030-01-30
Conditions
Hypertension
Interventions
OTHER
No Results Yet
398
Participants
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-06-07
Completion:
2026-12-31
Conditions
Gastric Adenocarcinoma
Gastroesophageal Junction (GEJ) Adenocarcinoma
Pancreatic Adenocarcinoma
Interventions
DRUG
No Results Yet
130
Participants
(HALT) Embrace Hydrogel Embolic System (HES) Study of Embolization in Peripheral Arterial Bleeds
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-12-12
Completion:
2026-01-31
Conditions
Arterial Bleeding in Solid Organs and Peripheral Arteries
Interventions
DEVICE
No Results Yet
37
Participants
Redefining FOLFIORINOX in Older Pancreatic Cancer Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-04-22
Completion:
2026-09-01
Conditions
Metastatic Pancreatic Cancer
Interventions
DRUG
No Results Yet
120
Participants
A Study of Combination Therapies With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer (MK-3475-06A)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-07-27
Completion:
2025-12-05
Conditions
Esophageal Squamous Cell Carcinoma (ESCC)
Interventions
BIOLOGICAL
DRUG
No Results Yet
760
Participants
Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-03-25
Completion:
2027-08-04
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
70
Participants
A Research Study Looking at Mim8 in Children With Haemophilia A With or Without Inhibitors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-04-04
Completion:
2024-11-13
Conditions
Haemophilia A With or Without Inhibitors
Interventions
DRUG
No Results Yet
20
Participants
Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2023-05-25
Completion:
2027-06-30
Conditions
T-cell Acute Lymphoblastic Leukemia
Interventions
DRUG
No Results Yet
140
Participants
Exploring Mechanisms of Massed Cognitive Processing Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-04-26
Completion:
2025-09-30
Conditions
PTSD
Interventions
BEHAVIORAL
No Results Yet
68
Participants
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-09-13
Completion:
2028-07-05
Conditions
Hodgkin Disease
Lymphoma, Non-Hodgkin
Interventions
DRUG
No Results Yet
662
Participants
A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-07-22
Completion:
2025-06-10
Conditions
Chronic Lymphocytic Leukemia
Leukemia, Lymphocytic
Leukemia, B-cell
Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
160
Participants
ERP to Improve Functioning in Veterans With OCD
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-10-03
Completion:
2026-05-31
Conditions
Obsessive Compulsive Disorder (OCD)
Comorbid Post-Traumatic Stress Disorder and OCD
Interventions
BEHAVIORAL
OTHER
No Results Yet
80
Participants
Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2024-03-12
Completion:
2026-12-30
Conditions
Ovarian Clear Cell Adenocarcinoma
Platinum-Sensitive Ovarian Carcinoma
Recurrent Endometrial Serous Adenocarcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Fallopian Tube Endometrioid Adenocarcinoma
Recurrent Fallopian Tube Serous Adenocarcinoma
Recurrent Ovarian Carcinoma
Recurrent Ovarian Clear Cell Adenocarcinoma
Recurrent Ovarian Endometrioid Adenocarcinoma
Recurrent Ovarian Serous Adenocarcinoma
Recurrent Platinum-Resistant Ovarian Carcinoma
Recurrent Primary Peritoneal Carcinoma
Recurrent Primary Peritoneal Clear Cell Adenocarcinoma
Recurrent Primary Peritoneal Endometrioid Adenocarcinoma
Recurrent Primary Peritoneal Serous Adenocarcinoma
Interventions
BIOLOGICAL
OTHER
No Results Yet
225
Participants
DIAMOND AF Post-Approval Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2022-02-28
Completion:
2026-01-31
Conditions
Paroxysmal Atrial Fibrillation
Interventions
DEVICE
No Results Yet
739
Participants
Study of Pembrolizumab/Vibostolimab Coformulation (MK-7684A) in Combination With Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (MK-7684A-007/KEYVIBE-007)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-03-24
Completion:
2024-09-24
Conditions
Metastatic Non-Small Cell Lung Cancer
Interventions
BIOLOGICAL
DRUG
350
Participants
A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-01-19
Completion:
2023-07-04
Conditions
Crohn Disease
Interventions
DRUG
72
Participants
A Study of Vedolizumab in Adults With Crohn's Disease (CD)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2023-03-20
Completion:
2025-10-31
Conditions
Crohn's Disease
Interventions
OTHER
No Results Yet
190
Participants
A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-03-28
Completion:
2027-12-13
Conditions
Solid Tumors
Interventions
DRUG
No Results Yet
44
Participants
Characterization of Pre-Term Neonatal Skin
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2023-10-13
Completion:
2024-08-17
Conditions
Skin Disorder
Interventions
DEVICE
DIAGNOSTIC_TEST
220
Participants
Expanding Technology-Enabled Nurse Delivered Chronic Disease Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-04-21
Completion:
2025-08-13
Conditions
Diabetes Mellitus, Type 2
Hypertension
Interventions
BEHAVIORAL
No Results Yet
68
Participants
A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2021-10-20
Completion:
2024-11-15
Conditions
Narcolepsy
Cataplexy
Excessive Daytime Sleepiness
Interventions
DRUG
No Results Yet
9
Participants
Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-12-08
Completion:
2025-10-21
Conditions
Knee Osteoarthritis
Interventions
DEVICE
No Results Yet
692
Participants
The PEERLESS Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-02-14
Completion:
2024-03-01
Conditions
Pulmonary Embolism
Pulmonary Thromboembolism
Interventions
DEVICE
59
Participants
Randomized Trial of Fresh Frozen Plasma Versus Albumin in Acute Burn Resuscitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-02-17
Completion:
2025-08-31
Conditions
Burns
Interventions
OTHER
No Results Yet
72
Participants
Intrathecal Morphine for Cesarean Delivery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2021-11-15
Completion:
2022-07-23
Conditions
Postoperative Pain
Interventions
DRUG
189
Participants
Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-06-28
Completion:
2028-10-01
Conditions
Advanced Extrapulmonary Neuroendocrine Carcinoma
Metastatic Extrapulmonary Neuroendocrine Carcinoma
Recurrent Extrapulmonary Neuroendocrine Carcinoma
Unresectable Extrapulmonary Neuroendocrine Carcinoma
Interventions
BIOLOGICAL
PROCEDURE
DRUG
OTHER
No Results Yet
30
Participants
A Phase 1 With Extension Cohort, Single Arm, Single Center, Open Label Trial of Belantamab Mafodotin for the Treatment of High-Risk Smoldering Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-05-18
Completion:
2027-02-02
Conditions
Myeloma
Interventions
DRUG
No Results Yet
1683
Participants
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2022-08-02
Completion:
2028-05-31
Conditions
Intracranial Arteriosclerosis
Stroke
Interventions
DRUG
OTHER
No Results Yet
100000
Participants
Economic and Clinical Outcomes of (Whole Exome) Sequencing in Tapestry
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2021-10-29
Completion:
2031-07-31
Conditions
Health Care Utilization
No Results Yet
38
Participants
Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2023-07-18
Completion:
2026-07-17
Conditions
Leukemia, B-Cell
Interventions
GENETIC
No Results Yet
400
Participants
STOP Persistent AF PAS
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2021-08-19
Completion:
2028-07-31
Conditions
Persistent Atrial Fibrillation
Interventions
DEVICE
No Results Yet
304
Participants
Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2021-11-02
Completion:
2029-09-07
Conditions
Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Interventions
DRUG
No Results Yet
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