Clinical Trials

Showing trials with last updates posted in 2025.

NCT05515341 | RECRUITING
50000 Participants

A DirEct to PatieNt Study in Chronic Pain

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2023-01-10
Completion: 2029-12-31
Conditions
Chronic Pain
Interventions
DEVICE
No Results Yet
NCT05502939 | ACTIVE_NOT_RECRUITING | NA
114 Participants

Music Training and Child Development Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-09-11
Completion: 2027-10-01
Conditions
Music
Interventions
BEHAVIORAL
No Results Yet
NCT05494398 | ENROLLING_BY_INVITATION | PHASE2/PHASE3
48 Participants

Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Open Label

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-03-12
Completion: 2027-09-30
Conditions
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT05478213 | RECRUITING | NA
10 Participants

Ventricular Tachycardia Mechanisms

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-10-25
Completion: 2025-12-31
Conditions
Ventricular Tachycardia
Interventions
DEVICE
No Results Yet
NCT05455671 | COMPLETED
48 Participants

Real-Time Assessment of Lung Structure and Function in Children and Young Adults With CF Using Electrical Impedance Tomography

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2022-08-01
Completion: 2024-08-20
Conditions
Cystic Fibrosis Healthy
No Results Yet
NCT05451914 | COMPLETED | NA
458 Participants

Effects of My Diabetes Care on Patient Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-07-06
Completion: 2025-07-14
Conditions
Diabetes Mellitus, Type 2
Interventions
OTHER
No Results Yet
NCT05451004 | RECRUITING | PHASE3
510 Participants

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-02-10
Completion: 2030-08-30
Conditions
Oropharyngeal Cancer
Interventions
OTHER RADIATION
No Results Yet
NCT05420844 | COMPLETED | NA
20 Participants

Pilot Study to Evaluate a Voice Journaling Application in Adolescents With Cystic Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-07-29
Completion: 2024-04-16
Conditions
Cystic Fibrosis
Interventions
OTHER
No Results Yet
NCT05419076 | RECRUITING | PHASE2
62 Participants

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-06-10
Completion: 2026-06-10
Conditions
Lung Cancer Lung Cancer Metastatic Brain Metastases Brain Metastases, Adult Small-cell Lung Cancer Small Cell Lung Carcinoma
Interventions
RADIATION PROCEDURE
No Results Yet
NCT05411718 | RECRUITING | PHASE2
40 Participants

A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-03-21
Completion: 2026-11-30
Conditions
T Cells Colorectal Cancer Lynch Syndrome
Interventions
DRUG
No Results Yet
NCT05410353 | ACTIVE_NOT_RECRUITING | NA
229 Participants

Choosing Healthy Activities and Lifestyle Management Through Portal Support

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-02-24
Completion: 2026-12-31
Conditions
Weight Loss Overweight and Obesity Behavior, Health
Interventions
BEHAVIORAL
No Results Yet
NCT05396885 | ACTIVE_NOT_RECRUITING | PHASE2
129 Participants

Study of Anitocabtagene-autoleucel in Relapsed or Refractory Multiple Myeloma (iMMagine-1)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-07-15
Completion: 2026-12-31
Conditions
Multiple Myeloma
Interventions
BIOLOGICAL
No Results Yet
NCT05383196 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
50 Participants

Onvansertib + Paclitaxel In TNBC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-09-30
Completion: 2026-02-15
Conditions
Breast Cancer Invasive Breast Cancer Unresectable Breast Carcinoma Locally Advanced Breast Cancer Metastatic Breast Cancer Inflammatory Breast Cancer Triple Negative Breast Cancer (TNBC) Hormone Receptor/Growth Factor Receptor-Negative Breast Cancer HER2-negative Breast Cancer Hormone Receptor Negative Breast Carcinoma
Interventions
DRUG
No Results Yet
NCT05382650 | TERMINATED
35 Participants

Survey of Human Rabies Immune Globulin Safety in Children

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2023-02-22
Completion: 2025-09-17
Conditions
Rabies Rabies Human Rabies Virus Infection Pediatrics
Interventions
BIOLOGICAL
No Results Yet
NCT05369416 | ACTIVE_NOT_RECRUITING | NA
70 Participants

Renal Metabolism in Salt-sensitive Human Blood Pressure

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2021-11-01
Completion: 2030-01-30
Conditions
Hypertension
Interventions
OTHER
No Results Yet
NCT05365581 | RECRUITING | PHASE1
398 Participants

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-06-07
Completion: 2026-12-31
Conditions
Gastric Adenocarcinoma Gastroesophageal Junction (GEJ) Adenocarcinoma Pancreatic Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT05364502 | ACTIVE_NOT_RECRUITING | NA
130 Participants

(HALT) Embrace Hydrogel Embolic System (HES) Study of Embolization in Peripheral Arterial Bleeds

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-12-12
Completion: 2026-01-31
Conditions
Arterial Bleeding in Solid Organs and Peripheral Arteries
Interventions
DEVICE
No Results Yet
NCT05360732 | ACTIVE_NOT_RECRUITING | PHASE2
37 Participants

Redefining FOLFIORINOX in Older Pancreatic Cancer Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-04-22
Completion: 2026-09-01
Conditions
Metastatic Pancreatic Cancer
Interventions
DRUG
No Results Yet
NCT05342636 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
120 Participants

A Study of Combination Therapies With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer (MK-3475-06A)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-07-27
Completion: 2025-12-05
Conditions
Esophageal Squamous Cell Carcinoma (ESCC)
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05327010 | RECRUITING | PHASE2
88 Participants

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-11-14
Completion: 2026-12-31
Conditions
Advanced Malignant Solid Neoplasm Metastatic Malignant Solid Neoplasm Unresectable Malignant Solid Neoplasm
Interventions
DRUG PROCEDURE
No Results Yet
NCT05317416 | RECRUITING | PHASE3
760 Participants

Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-03-25
Completion: 2027-08-04
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05306418 | COMPLETED | PHASE3
70 Participants

A Research Study Looking at Mim8 in Children With Haemophilia A With or Without Inhibitors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-04-04
Completion: 2024-11-13
Conditions
Haemophilia A With or Without Inhibitors
Interventions
DRUG
No Results Yet
NCT05289687 | RECRUITING | PHASE2
20 Participants

Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-05-25
Completion: 2027-06-30
Conditions
T-cell Acute Lymphoblastic Leukemia
Interventions
DRUG
No Results Yet
NCT05265039 | ACTIVE_NOT_RECRUITING | NA
140 Participants

Exploring Mechanisms of Massed Cognitive Processing Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-04-26
Completion: 2025-09-30
Conditions
PTSD
Interventions
BEHAVIORAL
No Results Yet
NCT05255601 | RECRUITING | PHASE1/PHASE2
68 Participants

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-09-13
Completion: 2028-07-05
Conditions
Hodgkin Disease Lymphoma, Non-Hodgkin
Interventions
DRUG
No Results Yet
NCT05254743 | RECRUITING | PHASE3
662 Participants

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-07-22
Completion: 2025-06-10
Conditions
Chronic Lymphocytic Leukemia Leukemia, Lymphocytic Leukemia, B-cell Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
NCT05240924 | RECRUITING | NA
160 Participants

ERP to Improve Functioning in Veterans With OCD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-10-03
Completion: 2026-05-31
Conditions
Obsessive Compulsive Disorder (OCD) Comorbid Post-Traumatic Stress Disorder and OCD
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT05231122 | RECRUITING | PHASE2
80 Participants

Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-03-12
Completion: 2026-12-30
Conditions
Ovarian Clear Cell Adenocarcinoma Platinum-Sensitive Ovarian Carcinoma Recurrent Endometrial Serous Adenocarcinoma Recurrent Fallopian Tube Carcinoma Recurrent Fallopian Tube Endometrioid Adenocarcinoma Recurrent Fallopian Tube Serous Adenocarcinoma Recurrent Ovarian Carcinoma Recurrent Ovarian Clear Cell Adenocarcinoma Recurrent Ovarian Endometrioid Adenocarcinoma Recurrent Ovarian Serous Adenocarcinoma Recurrent Platinum-Resistant Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Recurrent Primary Peritoneal Clear Cell Adenocarcinoma Recurrent Primary Peritoneal Endometrioid Adenocarcinoma Recurrent Primary Peritoneal Serous Adenocarcinoma
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05230524 | ACTIVE_NOT_RECRUITING
225 Participants

DIAMOND AF Post-Approval Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2022-02-28
Completion: 2026-01-31
Conditions
Paroxysmal Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT05226598 | ACTIVE_NOT_RECRUITING | PHASE3
739 Participants

Study of Pembrolizumab/Vibostolimab Coformulation (MK-7684A) in Combination With Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (MK-7684A-007/KEYVIBE-007)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-03-24
Completion: 2024-09-24
Conditions
Metastatic Non-Small Cell Lung Cancer
Interventions
BIOLOGICAL DRUG
NCT05197049 | ACTIVE_NOT_RECRUITING | PHASE3
350 Participants

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-01-19
Completion: 2023-07-04
Conditions
Crohn Disease
Interventions
DRUG
NCT05192863 | COMPLETED
72 Participants

A Study of Vedolizumab in Adults With Crohn's Disease (CD)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2023-03-20
Completion: 2025-10-31
Conditions
Crohn's Disease
Interventions
OTHER
No Results Yet
NCT05155332 | RECRUITING | PHASE1
190 Participants

A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-03-28
Completion: 2027-12-13
Conditions
Solid Tumors
Interventions
DRUG
No Results Yet
NCT05127044 | COMPLETED | NA
44 Participants

Characterization of Pre-Term Neonatal Skin

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-10-13
Completion: 2024-08-17
Conditions
Skin Disorder
Interventions
DEVICE DIAGNOSTIC_TEST
NCT05120544 | COMPLETED | NA
220 Participants

Expanding Technology-Enabled Nurse Delivered Chronic Disease Care

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-04-21
Completion: 2025-08-13
Conditions
Diabetes Mellitus, Type 2 Hypertension
Interventions
BEHAVIORAL
No Results Yet
NCT05113745 | COMPLETED | PHASE3
68 Participants

A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2021-10-20
Completion: 2024-11-15
Conditions
Narcolepsy Cataplexy Excessive Daytime Sleepiness
Interventions
DRUG
No Results Yet
NCT05112926 | COMPLETED | NA
9 Participants

Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-12-08
Completion: 2025-10-21
Conditions
Knee Osteoarthritis
Interventions
DEVICE
No Results Yet
NCT05111613 | COMPLETED | NA
692 Participants

The PEERLESS Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-02-14
Completion: 2024-03-01
Conditions
Pulmonary Embolism Pulmonary Thromboembolism
Interventions
DEVICE
NCT05069922 | COMPLETED | NA
59 Participants

Randomized Trial of Fresh Frozen Plasma Versus Albumin in Acute Burn Resuscitation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-02-17
Completion: 2025-08-31
Conditions
Burns
Interventions
OTHER
No Results Yet
NCT05069012 | COMPLETED | PHASE4
72 Participants

Intrathecal Morphine for Cesarean Delivery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2021-11-15
Completion: 2022-07-23
Conditions
Postoperative Pain
Interventions
DRUG
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