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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07157787 | RECRUITING | PHASE2
30 Participants

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-19
Completion: 2027-02-12
Conditions
Primary Membranous Nephropathy
Interventions
DRUG
No Results Yet
NCT07157254 | RECRUITING | PHASE2
60 Participants

A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-13
Completion: 2030-01-31
Conditions
Angelman Syndrome
Interventions
OTHER DRUG
No Results Yet
NCT07156175 | RECRUITING | PHASE2
54 Participants

A Study to Investigate the Efficacy and Safety of SAR444336 in Adults With Microscopic Colitis in Clinical Remission

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-14
Completion: 2027-04-08
Conditions
Microscopic Colitis
Interventions
DRUG
No Results Yet
NCT07155317 | RECRUITING | PHASE2
99 Participants

Time-of-Day Specified Immunotherapy for Advanced Melanoma, The TIME Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-29
Completion: 2026-12-31
Conditions
Advanced Acral Melanoma Advanced Cutaneous Melanoma Advanced Mucosal Melanoma Clinical Stage IV Cutaneous Melanoma AJCC v8 Metastatic Acral Melanoma Metastatic Cutaneous Melanoma Metastatic Mucosal Melanoma Unresectable Acral Melanoma Unresectable Cutaneous Melanoma Unresectable Mucosal Melanoma
Interventions
PROCEDURE BIOLOGICAL OTHER
No Results Yet
NCT07155174 | NOT_YET_RECRUITING | PHASE2/PHASE3
180 Participants

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-06
Completion: 2029-05-31
Conditions
Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT07154511 | RECRUITING | PHASE1/PHASE2
45 Participants

Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-07
Completion: 2027-05-31
Conditions
Parkinson Disease Parkinson Disease Dementia
Interventions
DRUG
No Results Yet
NCT07153003 | NOT_YET_RECRUITING | PHASE4
560 Participants

Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2030-09-01
Conditions
Post Operative Pain
Interventions
DRUG
No Results Yet
NCT07152249 | RECRUITING | NA
13120 Participants

Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-03
Completion: 2026-09-30
Conditions
Postoperative Nausea Postoperative Vomiting
Interventions
OTHER
No Results Yet
NCT07149428 | NOT_YET_RECRUITING
80 Participants

Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-17
Completion: 2029-09-30
Conditions
Respiratory Tract Infection Smell Disorder Influenza Rhinosinusitis COVID-19 Depression Parosmia Hyposomia Normosomia Anosmia
No Results Yet
NCT07148713 | RECRUITING | NA
60 Participants

Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-19
Completion: 2026-06-30
Conditions
Nutrition Type 2 Diabetes T2DM T2DM (Type 2 Diabetes Mellitus) Diabetes Education Diabetes Type 2 Diabetes Mellitis
Interventions
BEHAVIORAL
No Results Yet
NCT07146646 | RECRUITING | PHASE2
27 Participants

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2027-02-28
Conditions
Biliary Tract Cancer Biliary Tract Neoplasms Cholangiocarcinoma Gallbladder Cancer Gallbladder Carcinoma
Interventions
DRUG
No Results Yet
NCT07145918 | RECRUITING | PHASE2
258 Participants

A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-04
Completion: 2028-02-29
Conditions
Schizophrenia
Interventions
DRUG
No Results Yet
NCT07144826 | NOT_YET_RECRUITING | EARLY_PHASE1
161 Participants

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-09
Completion: 2027-07-09
Conditions
Advanced Ovarian Carcinoma Recurrent Ovarian Carcinoma Stage II Ovarian Cancer AJCC v8 Stage III Ovarian Cancer AJCC v8 Stage IV Ovarian Cancer AJCC v8
Interventions
PROCEDURE DRUG DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT07144631 | RECRUITING | NA
15 Participants

Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-15
Completion: 2026-09-30
Conditions
Restless Leg Disorder Restless Leg Syndrome (RLS) Pregnancy Sleep Disorder (Disorder)
Interventions
DEVICE
No Results Yet
NCT07142811 | RECRUITING | PHASE2
100 Participants

A Study to Evaluate Tobevibart+Elebsiran Versus Bulevirtide in Chronic HDV Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-05
Completion: 2026-11-30
Conditions
Viral Hepatitis
Interventions
DRUG
No Results Yet
NCT07142343 | RECRUITING | PHASE4
5 Participants

A Study to Test the Safety of Pozelimab in Pediatric Participants 1 to 5 Years of Age With a Rare Disease Called CHAPLE (Complement Hyperactivation, Angiopathic Thrombosis, Protein-losing Enteropathy) Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-23
Completion: 2029-08-24
Conditions
CHAPLE Disease
Interventions
DRUG
No Results Yet
NCT07137455 | NOT_YET_RECRUITING | NA
50 Participants

EDEN Intracardiac Electrogram Recording and Classifying System

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-17
Completion: 2026-11-01
Conditions
Ventricular Arrhythmia
Interventions
DEVICE
No Results Yet
NCT07137442 | NOT_YET_RECRUITING
75 Participants

Distinguishing Tics and Functional Tics Using Clinical Neurophysiological Techniques

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-17
Completion: 2034-08-01
Conditions
Tics Functional Tics
No Results Yet
NCT07137429 | NOT_YET_RECRUITING
400 Participants

Platelet Volunteers, Longitudinal and Multi-omic Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-17
Completion: 2041-09-15
Conditions
Thrombosis
No Results Yet
NCT07133633 | RECRUITING | PHASE2
315 Participants

A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-26
Completion: 2027-06-15
Conditions
Radiographic Axial Spondyloarthritis
Interventions
DRUG
No Results Yet
NCT07128901 | NOT_YET_RECRUITING | NA
6 Participants

Lower-Limb Exoskeleton Technology for Non-Ambulatory Individuals With Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-01
Completion: 2026-12-01
Conditions
Spinal Cord Injuries
Interventions
DEVICE
No Results Yet
NCT07128628 | NOT_YET_RECRUITING | PHASE2
423 Participants

A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2026-11-30
Conditions
Dry Eye Disease
Interventions
DRUG
No Results Yet
NCT07128550 | RECRUITING | PHASE3
150 Participants

A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-30
Completion: 2026-12-31
Conditions
Viral Hepatitis
Interventions
DRUG
No Results Yet
NCT07128303 | RECRUITING | PHASE1
178 Participants

Study of GS-5319 in Adults With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-28
Completion: 2028-05-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT07125326 | NOT_YET_RECRUITING | NA
564 Participants

How the Method of Bladder Emptying After Epidural Placement in Labor Affects Postpartum Voiding

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2026-08-31
Conditions
Urinary Retention Urinary Tract Infection (Diagnosis) Postpartum Acute Urinary Retention Postpartum Care Voiding Dysfunction
Interventions
PROCEDURE
No Results Yet
NCT07125027 | RECRUITING | NA
32 Participants

A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-15
Completion: 2026-11-30
Conditions
Lumbosacral Radiculopathy Sciatica Chronic Low Back Pain With a Neuropathic Component Radiculopathy Lumbar Chronic Pain (Back / Neck)
Interventions
BEHAVIORAL
No Results Yet
NCT07117136 | RECRUITING
200 Participants

Blinatumomab Consolidation in Real World

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-28
Completion: 2029-05-14
Conditions
B-Cell Acute Lymphoblastic Leukaemia
No Results Yet
NCT07116226 | ENROLLING_BY_INVITATION | NA
40 Participants

Learning How to Implement and Use a Ketogenic Diet to Improve Mental Health

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-01
Completion: 2025-12-01
Conditions
Medical Keto Diet
Interventions
OTHER
No Results Yet
NCT07111182 | RECRUITING | NA
8 Participants

Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-27
Completion: 2027-11-30
Conditions
Brain Neoplasms
Interventions
DEVICE
No Results Yet
NCT07111065 | NOT_YET_RECRUITING | PHASE2
300 Participants

FAST for DM Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-17
Completion: 2030-11-03
Conditions
Dermatomyositis (DM) Juvenile Dermatomyositis (JDM)
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT07111052 | RECRUITING | NA
50 Participants

Lock and Protect: Reducing Adolescent Access to Lethal Means of Suicide

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-11
Completion: 2026-12-31
Conditions
Suicide Suicide Attempt Adolescent Suicidality Suicide Ideation
Interventions
BEHAVIORAL
No Results Yet
NCT07110246 | RECRUITING | PHASE2
96 Participants

Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-07
Completion: 2032-03-31
Conditions
BRAF V600 Mutation Low-grade Glioma Low Grade Glioma of Brain Recurrent Low Grade Glioma
Interventions
DRUG PROCEDURE
No Results Yet
NCT07102394 | NOT_YET_RECRUITING | PHASE1
10 Participants

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-02-01
Completion: 2026-12-31
Conditions
NF1 Neurofibromatosis Cutaneous Neurofibroma Neurofibroma Von Recklinghausen Disease Neurofibromas
Interventions
DRUG
No Results Yet
NCT07101289 | RECRUITING | NA
900 Participants

Eat Well Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-22
Completion: 2026-12-31
Conditions
Congestive Heart Failure Chronic
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07100080 | RECRUITING | PHASE2/PHASE3
596 Participants

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-05
Completion: 2028-09-15
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT07099092 | NOT_YET_RECRUITING | EARLY_PHASE1
80 Participants

Causal Mechanisms of Odor-Guided Behavior in Humans

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-17
Completion: 2035-07-14
Conditions
Normal Physiology
Interventions
DEVICE
No Results Yet
NCT07099053 | NOT_YET_RECRUITING
400 Participants

Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-17
Completion: 2029-12-12
Conditions
Aging
No Results Yet
NCT07098364 | RECRUITING | PHASE1/PHASE2
33 Participants

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2030-10-04
Conditions
Recurrent Diffuse Large B-Cell Lymphoma Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Recurrent Grade 3b Follicular Lymphoma Recurrent High-Grade B-Cell Lymphoma Recurrent Indolent B-Cell Non-Hodgkin Lymphoma Recurrent Primary Mediastinal Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Refractory Grade 3b Follicular Lymphoma Refractory High-Grade B-Cell Lymphoma Refractory Indolent B-Cell Non-Hodgkin Lymphoma Refractory Primary Mediastinal Large B-Cell Lymphoma
Interventions
PROCEDURE BIOLOGICAL
No Results Yet
NCT07097506 | RECRUITING | PHASE2
40 Participants

Effect of Ketone Esters on Liver Fat Content and Metabolic Function

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-26
Completion: 2027-07-31
Conditions
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease Obesity Overweight (BMI > 25)
Interventions
DRUG OTHER
No Results Yet
NCT07095556 | RECRUITING | NA
39 Participants

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-05
Completion: 2026-12-31
Conditions
Wound Healing and Prevention Oral Inflammation Photobiomodulation Post-operative Pain Management Tooth Extraction Site Healing
Interventions
OTHER
No Results Yet
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