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Clinical Trials

NCT06456762 | RECRUITING | NA
90 Participants

Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-01
Completion: 2026-12-31
Conditions
Parents Self Efficacy Mental Health Literacy Psychiatric Emergency
Interventions
BEHAVIORAL
No Results Yet
NCT06455098 | RECRUITING | NA
440 Participants

A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-28
Completion: 2026-05-30
Conditions
Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT06453694 | RECRUITING | PHASE2
20 Participants

Efgartigimod for the Treatment of Acute Optic Neuritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-08-12
Completion: 2026-12-31
Conditions
Optic Neuritis
Interventions
DRUG
No Results Yet
NCT06449651 | RECRUITING | PHASE3
39 Participants

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-11-11
Completion: 2029-12-05
Conditions
Thrombocytopenia, Neonatal Alloimmune
Interventions
DRUG
No Results Yet
NCT06445972 | RECRUITING | PHASE1/PHASE2
90 Participants

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-07
Completion: 2026-12-28
Conditions
Gastroesophageal Junction Gastroesophageal Adenocarcinoma Esophageal Neoplasms Esophageal Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06439836 | RECRUITING | PHASE1
27 Participants

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-05
Completion: 2027-06-01
Conditions
Metastatic Urothelial Carcinoma Unresectable Urothelial Carcinoma
Interventions
PROCEDURE BIOLOGICAL
No Results Yet
NCT06434337 | RECRUITING
600 Participants

Evaluation of a Novel Point-of-Care Diagnostic Test for Human Papillomavirus (HPV)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-23
Completion: 2026-03-31
Conditions
Human Papillomavirus
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06425991 | ACTIVE_NOT_RECRUITING | PHASE1
108 Participants

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-07
Completion: 2027-02-28
Conditions
Relapsed or Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06420089 | RECRUITING | PHASE1
30 Participants

CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-04
Completion: 2028-08-30
Conditions
T Cell Non-Hodgkin Lymphoma
Interventions
DRUG
No Results Yet
NCT06418204 | RECRUITING
2000 Participants

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-30
Completion: 2028-08-31
Conditions
Breast Carcinoma Colorectal Carcinoma Lung Non-Small Cell Carcinoma Melanoma Non-Hodgkin Lymphoma
Interventions
OTHER
No Results Yet
NCT06414902 | RECRUITING | PHASE1
60 Participants

18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-04
Completion: 2027-10-01
Conditions
Esophageal Cancer
Interventions
DRUG
No Results Yet
NCT06408935 | RECRUITING | PHASE3
112 Participants

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-17
Completion: 2027-06-08
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
NCT06406751 | ENROLLING_BY_INVITATION | NA
50 Participants

Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-28
Completion: 2027-06-30
Conditions
Dental Prosthesis
Interventions
DEVICE
No Results Yet
NCT06403605 | COMPLETED | NA
148 Participants

Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-09-13
Completion: 2025-01-17
Conditions
Diabetic Foot Ulcer Ulcer Foot Diabetic Foot
Interventions
DEVICE
Results Available
NCT06398639 | RECRUITING | NA
1500 Participants

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-07
Completion: 2028-04-30
Conditions
Prostate Cancer Polygenic Risk Score
Interventions
OTHER
No Results Yet
NCT06398626 | RECRUITING
300 Participants

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-17
Completion: 2027-05-04
Conditions
Colitis, Ulcerative
Interventions
DRUG
No Results Yet
NCT06394869 | RECRUITING | NA
1000 Participants

Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-29
Completion: 2027-01-31
Conditions
Hematuria - Cause Not Known
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06393374 | RECRUITING | PHASE3
1530 Participants

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-24
Completion: 2030-12-16
Conditions
Triple-Negative Breast Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06385080 | RECRUITING | PHASE1/PHASE2
287 Participants

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-22
Completion: 2027-12-27
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06384625 | COMPLETED | NA
20 Participants

Developing and Evaluating an Indoor Air Pollution Intervention Among Cardiovascular Patients: the AIRWISE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-24
Completion: 2025-11-05
Conditions
Coronary Heart Disease Cardiovascular Diseases Environmental Exposure
Interventions
OTHER
No Results Yet
NCT06377514 | COMPLETED | NA
223 Participants

Clinical Investigation of the TECNISยฎ Next-Generation Intraocular Lens

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-03
Completion: 2025-04-23
Conditions
Cataracts
Interventions
DEVICE
No Results Yet
NCT06366633 | COMPLETED | NA
5 Participants

Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-10-29
Completion: 2025-05-31
Conditions
Orthopedic Disorder Nontraumatic Injury Substance Use Upper Extremity Problem
Interventions
BEHAVIORAL
No Results Yet
NCT06343831 | RECRUITING | NA
15 Participants

Quantitative Assessment of Autologous Fat Transfer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-01-25
Completion: 2026-12-31
Conditions
Autologous Fat Grafting
Interventions
PROCEDURE
No Results Yet
NCT06335953 | COMPLETED | NA
360 Participants

ALIGN: Aligning Medications With What Matters Most (Demonstration)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-07
Completion: 2025-09-16
Conditions
Polypharmacy Alzheimer's Disease and Related Dementias Mild Cognitive Impairment
Interventions
BEHAVIORAL
No Results Yet
NCT06334133 | RECRUITING | PHASE3
150 Participants

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-14
Completion: 2026-09-30
Conditions
Diabetes Mellitus, Type 1
Interventions
DRUG
No Results Yet
NCT06327152 | ACTIVE_NOT_RECRUITING | PHASE2
80 Participants

Caffeine Use in the Management of Preterm Infants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-02-22
Completion: 2026-12-31
Conditions
Apnea of Prematurity
Interventions
DRUG OTHER
No Results Yet
NCT06326411 | RECRUITING | PHASE1
230 Participants

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-09
Completion: 2028-11-30
Conditions
Oncology MEK Mutation RAF Gene Mutation Ras (KRAS or NRAS) Gene Mutation Melanoma NSCLC Glioma Solid Tumor, Adult MAPK Pathway Gene Mutation
Interventions
DRUG
No Results Yet
NCT06323980 | RECRUITING | NA
168 Participants

INHANCE Stemless Reverse Shoulder IDE

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-04
Completion: 2027-11-10
Conditions
Arthroplasty Replacement Shoulder
Interventions
DEVICE
No Results Yet
NCT06320808 | COMPLETED | NA
330 Participants

Evaluating FDA's Proposed Patient Medication Information Handout

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-03-03
Completion: 2024-03-04
Conditions
Knowledge Attitude
Interventions
OTHER
No Results Yet
NCT06320054 | RECRUITING | NA
100 Participants

Preventing Obstetric Complications With Dietary Intervention

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-06-12
Completion: 2026-02-28
Conditions
Gestational Diabetes Gestational Hypertension High Risk Pregnancy Preeclampsia
Interventions
BEHAVIORAL
No Results Yet
NCT06319820 | RECRUITING | PHASE3
560 Participants

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-18
Completion: 2028-06-28
Conditions
Non-Muscle Invasive Bladder Cancer
Interventions
COMBINATION_PRODUCT DRUG
No Results Yet
NCT06316973 | COMPLETED | PHASE1
32 Participants

A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-02-07
Completion: 2024-05-30
Conditions
Substance Use Disorders Methamphetamine Abuse Methamphetamine Intoxication
Interventions
DRUG
Results Available
NCT06313593 | RECRUITING | PHASE1
186 Participants

A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-08-08
Completion: 2028-10-09
Conditions
Myeloproliferative Neoplasms
Interventions
DRUG
No Results Yet
NCT06312137 | RECRUITING | PHASE3
780 Participants

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-03
Completion: 2034-02-21
Conditions
Non Small Cell Lung Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06311578 | RECRUITING | PHASE1
96 Participants

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-04-10
Completion: 2028-11-08
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06310655 | COMPLETED | NA
10 Participants

Online Proton Adaptive Radiotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-02
Completion: 2025-08-08
Conditions
Solid Tumor
Interventions
RADIATION
No Results Yet
NCT06297603 | ACTIVE_NOT_RECRUITING | PHASE3
320 Participants

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-03-15
Completion: 2026-10-31
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
NCT06296394 | RECRUITING
146 Participants

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2024-05-29
Completion: 2030-02-01
Conditions
Cystic Fibrosis Parenthood Status
Interventions
OTHER
No Results Yet
NCT06295692 | ACTIVE_NOT_RECRUITING | PHASE3
19 Participants

A Study of JNJ-77242113 for the Treatment of Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-02-09
Completion: 2025-01-14
Conditions
Generalized Pustular Psoriasis Erythrodermic Psoriasis
Interventions
DRUG
No Results Yet
NCT06285318 | RECRUITING
900 Participants

A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2023-12-18
Completion: 2026-06-30
Conditions
Relapsed/Refractory Multiple Myeloma (RRMM)
Interventions
OTHER
No Results Yet
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