Clinical Trials

NCT06549036 | NOT_YET_RECRUITING | NA

228 Participants

Veteran Peer Navigators to Promote Shared Decision Making for PSA Screening

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2026-01-05

Completion: 2028-03-01

Conditions

Prostate Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06548360 | RECRUITING | PHASE3

180 Participants

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-01-24

Completion: 2026-08-10

Conditions

NonSegmental Vitiligo

Interventions

DRUG

No Results Yet

NCT06547489 | RECRUITING | PHASE2

164 Participants

GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-02-03

Completion: 2026-08-31

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT06545682 | RECRUITING | PHASE1

50 Participants

Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-15

Completion: 2027-08-03

Conditions

Melanoma (Skin Cancer) Breast Cancer Brain Metastasases

Interventions

DRUG

No Results Yet

NCT06544616 | RECRUITING | PHASE2

498 Participants

A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-07-22

Completion: 2031-07-17

Conditions

Preclinical Alzheimer's Disease

Interventions

DRUG

No Results Yet

NCT06540144 | ENROLLING_BY_INVITATION | PHASE3

12 Participants

An Extension Study Evaluating 6-week Treatment Cycles of Rozanolixizumab in Pediatric Study Participants With Generalized Myasthenia Gravis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-08

Completion: 2027-08-17

Conditions

Generalized Myasthenia Gravis

Interventions

DRUG

No Results Yet

NCT06535178 | RECRUITING | NA

30 Participants

The Influence of Sleep on Cardiovascular Outcomes

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-07-01

Completion: 2026-09-30

Conditions

Circadian Rhythm Cardiometabolic Health Vascular Health Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06533098 | RECRUITING | PHASE3

50 Participants

A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-02-10

Completion: 2027-12-15

Conditions

Thrombocytopenia, Neonatal Alloimmune

Interventions

DRUG

No Results Yet

NCT06529835 | RECRUITING | NA

80 Participants

A Comparison of NeuroSpan Bridge, NeuraGen Nerve Guide, and Nerve Autograft for Peripheral Nerve Repair

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-03-21

Completion: 2027-12-31

Conditions

Peripheral Nerve Injuries

Interventions

DEVICE

No Results Yet

NCT06528496 | RECRUITING | PHASE2

45 Participants

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-07-22

Completion: 2029-07-22

Conditions

High-risk Neuroblastoma Neuroblastoma Childhood Neuroblastoma

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT06527872 | RECRUITING

300 Participants

Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-04

Completion: 2029-03-29

Conditions

Lupus Nephritis

Interventions

OTHER

No Results Yet

NCT06524973 | RECRUITING | NA

136 Participants

Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care Givers

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-07

Completion: 2027-05-03

Conditions

Metastatic Pancreatic Adenocarcinoma

Interventions

OTHER

No Results Yet

NCT06517758 | RECRUITING | PHASE3

146 Participants

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 75 Years With gMG.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-07-31

Completion: 2026-12-28

Conditions

Generalized Myasthenia Gravis

Interventions

DRUG OTHER

No Results Yet

NCT06516965 | RECRUITING | PHASE3

330 Participants

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-10

Completion: 2026-10-19

Conditions

Prurigo Nodularis

Interventions

DRUG

No Results Yet

NCT06516952 | RECRUITING | PHASE3

330 Participants

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-10

Completion: 2026-10-19

Conditions

Prurigo Nodularis

Interventions

DRUG

No Results Yet

NCT06504914 | RECRUITING | NA

24 Participants

Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-02-05

Completion: 2026-06-30

Conditions

Hypertension Obesity Nutrition, Healthy

Interventions

BEHAVIORAL

No Results Yet

NCT06501625 | RECRUITING | PHASE1/PHASE2

52 Participants

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-12-16

Completion: 2026-07-23

Conditions

Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Interventions

DRUG

No Results Yet

NCT06500884 | RECRUITING | PHASE2

130 Participants

A Study to Evaluate Preventive Treatments for Talquetamab-related Oral Toxicity

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-08-26

Completion: 2026-04-15

Conditions

Relapse Multiple Myeloma Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06500455 | RECRUITING | PHASE3

269 Participants

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-12-12

Completion: 2028-06-30

Conditions

Anatomic Stage IV Breast Cancer AJCC v8 Metastatic Breast Carcinoma Metastatic Digestive System Carcinoma Metastatic Lung Non-Small Cell Carcinoma Metastatic Malignant Neoplasm in the Brain Metastatic Malignant Solid Neoplasm Metastatic Melanoma Metastatic Renal Cell Carcinoma Stage IV Lung Cancer AJCC v8 Stage IV Renal Cell Cancer AJCC v8

Interventions

PROCEDURE RADIATION

No Results Yet

NCT06479447 | RECRUITING | NA

17000 Participants

Patient Outcome Reporting for Timely Assessments of Life With Post-Traumatic Stress Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-07-15

Completion: 2026-07-14

Conditions

PTSD

Interventions

OTHER

No Results Yet

NCT06478160 | RECRUITING | NA

216 Participants

Closed-blood Sampling Devices in the Adult Critically Ill Patient

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-11-11

Completion: 2026-06-07

Conditions

Acceptability of Health Care

Interventions

DEVICE OTHER

No Results Yet

NCT06477289 | RECRUITING

65 Participants

Peripheral Arterial Tonometry and Neurocognition in Sickle Cell Disease

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2024-09-16

Completion: 2027-06-30

Conditions

Sickle Cell Disease

No Results Yet

NCT06472245 | RECRUITING | PHASE3

363 Participants

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-12-03

Completion: 2027-12-15

Conditions

Patients With Non-Small Cell Lung Cancer

Interventions

DRUG DEVICE

No Results Yet

NCT06472128 | RECRUITING | NA

200 Participants

Novel Digital Application for Patients With Acute Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-21

Completion: 2029-04-30

Conditions

Relapsed Adult Acute Myeloid Leukemia Primary Refractory Acute Myeloid Leukemia High Risk Acute Myeloid Leukemia

Interventions

BEHAVIORAL

No Results Yet

NCT06469944 | RECRUITING | PHASE1/PHASE2

130 Participants

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-09-20

Completion: 2027-01-17

Conditions

Gastroesophageal Junction Gastroesophageal Adenocarcinoma Esophageal Neoplasms Esophageal Cancer

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT06469151 | COMPLETED | PHASE1

84 Participants

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-06-24

Completion: 2025-10-22

Conditions

Healthy Participants

Interventions

DRUG

No Results Yet

NCT06464926 | RECRUITING | NA

148 Participants

Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-06-23

Completion: 2030-06-30

Conditions

Nausea Vomiting

Interventions

DEVICE

No Results Yet

NCT06456762 | RECRUITING | NA

90 Participants

Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-08-01

Completion: 2026-12-31

Conditions

Parents Self Efficacy Mental Health Literacy Psychiatric Emergency

Interventions

BEHAVIORAL

No Results Yet

NCT06455098 | RECRUITING | NA

440 Participants

A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-06-28

Completion: 2026-05-30

Conditions

Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT06453694 | RECRUITING | PHASE2

20 Participants

Efgartigimod for the Treatment of Acute Optic Neuritis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-08-12

Completion: 2026-12-31

Conditions

Optic Neuritis

Interventions

DRUG

No Results Yet

NCT06449651 | RECRUITING | PHASE3

39 Participants

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-11-11

Completion: 2029-12-05

Conditions

Thrombocytopenia, Neonatal Alloimmune

Interventions

DRUG

No Results Yet

NCT06445972 | RECRUITING | PHASE1/PHASE2

90 Participants

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-08-07

Completion: 2026-12-28

Conditions

Gastroesophageal Junction Gastroesophageal Adenocarcinoma Esophageal Neoplasms Esophageal Cancer

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT06439836 | RECRUITING | PHASE1

27 Participants

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-05-05

Completion: 2027-06-01

Conditions

Metastatic Urothelial Carcinoma Unresectable Urothelial Carcinoma

Interventions

PROCEDURE BIOLOGICAL

No Results Yet

NCT06434337 | RECRUITING

600 Participants

Evaluation of a Novel Point-of-Care Diagnostic Test for Human Papillomavirus (HPV)

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2024-07-23

Completion: 2026-03-31

Conditions

Human Papillomavirus

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06425991 | ACTIVE_NOT_RECRUITING | PHASE1

108 Participants

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-06-07

Completion: 2027-02-28

Conditions

Relapsed or Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06420089 | RECRUITING | PHASE1

30 Participants

CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-04

Completion: 2028-08-30

Conditions

T Cell Non-Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT06418204 | RECRUITING

2000 Participants

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2025-01-30

Completion: 2028-08-31

Conditions

Breast Carcinoma Colorectal Carcinoma Lung Non-Small Cell Carcinoma Melanoma Non-Hodgkin Lymphoma

Interventions

OTHER

No Results Yet

NCT06414902 | RECRUITING | PHASE1

60 Participants

18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-09-04

Completion: 2027-10-01

Conditions

Esophageal Cancer

Interventions

DRUG

No Results Yet

NCT06408935 | RECRUITING | PHASE3

112 Participants

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-04-17

Completion: 2027-06-08

Conditions

Crohn's Disease

Interventions

DRUG

No Results Yet

NCT06406751 | ENROLLING_BY_INVITATION | NA

50 Participants

Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-08-28

Completion: 2027-06-30

Conditions

Dental Prosthesis

Interventions

DEVICE

No Results Yet