Clinical Trials

NCT05627635 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
20 Participants

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-05-03
Completion: 2026-06-23
Conditions
Metastatic Colon Adenocarcinoma Metastatic Colorectal Adenocarcinoma Metastatic Microsatellite Stable Colorectal Carcinoma Metastatic Rectal Adenocarcinoma Stage IV Colon Cancer AJCC v8 Stage IV Colorectal Cancer AJCC v8 Stage IV Rectal Cancer AJCC v8
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT05624996 | RECRUITING | PHASE3
474 Participants

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-07-12
Completion: 2031-10-15
Conditions
Locally Advanced Lung Non-Small Cell Carcinoma Stage IIB Lung Cancer AJCC v8 Stage III Lung Cancer AJCC v8
Interventions
DRUG PROCEDURE BIOLOGICAL RADIATION OTHER
No Results Yet
NCT05622344 | RECRUITING | NA
48 Participants

StableEyes With Active Neurofeedback

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-08-08
Completion: 2026-09-30
Conditions
Vestibular Disorder Vestibular Schwannoma Space Motion Sickness Motion Sickness
Interventions
BEHAVIORAL DEVICE
No Results Yet
NCT05621304 | RECRUITING
255 Participants

Optimizing HBV Care Cascade Among Foreign-Born in the United States (FOCUS-HBV Study)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2017-01-03
Completion: 2025-12-29
Conditions
Chronic Hepatitis B Virus (Hbv)
No Results Yet
NCT05617040 | TERMINATED | PHASE1/PHASE2
22 Participants

Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-01-30
Completion: 2025-02-05
Conditions
Prostate Cancer
Interventions
BIOLOGICAL
NCT05616650 | RECRUITING | PHASE2
42 Participants

Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-10-19
Completion: 2027-12-01
Conditions
Prostatic Neoplasms Prostate Cancer Prostate Adenocarcinoma
Interventions
DRUG RADIATION
No Results Yet
NCT05609669 | ACTIVE_NOT_RECRUITING | NA
10 Participants

Continuous And Data-drivEN CarE (CADENCE) Pilot

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-08-23
Completion: 2027-01-30
Conditions
Pregnancy Related Opioid Use Disorder
Interventions
OTHER
No Results Yet
NCT05609331 | TERMINATED | NA
3 Participants

Feasibility, Safety, and Efficacy of Stereotactic MRI-Guided Adaptive Radiation Therapy (SMART) for Central Lung Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-17
Completion: 2025-11-05
Conditions
Lung Cancer
Interventions
OTHER RADIATION
No Results Yet
NCT05602142 | NOT_YET_RECRUITING | PHASE1/PHASE2
20 Participants

Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-02-28
Completion: 2027-01-31
Conditions
ALS
Interventions
DRUG
No Results Yet
NCT05595642 | RECRUITING | PHASE3
1290 Participants

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-12-29
Completion: 2025-06-24
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
DRUG
No Results Yet
NCT05592015 | RECRUITING | PHASE2
28 Participants

Ruxolitinib for the Treatment of T-Cell Large Granular Lymphocytic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-05-03
Completion: 2025-12-31
Conditions
T-Cell Large Granular Lymphocyte Leukemia
Interventions
DRUG
No Results Yet
NCT05588167 | RECRUITING
100 Participants

Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-28
Completion: 2026-09-30
Conditions
Niemann-Pick Disease, Type C
No Results Yet
NCT05582889 | COMPLETED | NA
64 Participants

Move For Your Health for Older Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-04
Completion: 2024-03-01
Conditions
Cancer Survivors
Interventions
BEHAVIORAL
NCT05580458 | RECRUITING | PHASE1/PHASE2
225 Participants

Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-03-13
Completion: 2027-02-01
Conditions
Herpes Zoster
Interventions
BIOLOGICAL
No Results Yet
NCT05576090 | RECRUITING | NA
240 Participants

UCLA REST Study (REsearch on Sleep Techniques)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-04-03
Completion: 2026-06-30
Conditions
Sleep Disturbance Inflammation Psychosocial Functioning
Interventions
BEHAVIORAL
No Results Yet
NCT05570747 | COMPLETED
35 Participants

Simulated In-House Usability Study of Eclipse Continuous Positive Airway Pressure (CPAP) Device

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-19
Completion: 2022-11-11
Conditions
Obstructive Sleep Apnea
Interventions
OTHER
NCT05569122 | RECRUITING | PHASE1
90 Participants

Applying pGz in Mitochondrial Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-03-22
Completion: 2027-09-30
Conditions
Mitochondrial Myopathies Mitochondrial Diseases
Interventions
DIAGNOSTIC_TEST DEVICE DRUG
No Results Yet
NCT05568888 | TERMINATED | PHASE3
1366 Participants

Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study )

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-03-28
Completion: 2024-10-29
Conditions
Traumatic Injury
Interventions
DRUG
NCT05559047 | COMPLETED
70 Participants

Field Usability Study of Eclipse Mask

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-10
Completion: 2023-01-25
Conditions
Obstructive Sleep Apnea
Interventions
DEVICE
NCT05558904 | RECRUITING | PHASE1/PHASE2
60 Participants

An Investigational Scan (Me-4FDG PET/CT) for the Detection of Sodium-Glucose Transport for Early Diagnosis of Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-01-19
Completion: 2026-10-01
Conditions
Lung Adenocarcinoma
Interventions
DRUG PROCEDURE OTHER
No Results Yet
NCT05554406 | RECRUITING | PHASE2
335 Participants

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-25
Completion: 2027-03-31
Conditions
Acute Myeloid Leukemia Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Acute Myeloid Leukemia Post Cytotoxic Therapy Acute Myeloid Leukemia, Myelodysplasia-Related
Interventions
DRUG PROCEDURE
No Results Yet
NCT05552222 | RECRUITING | PHASE3
1590 Participants

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-25
Completion: 2031-04-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05546658 | RECRUITING | EARLY_PHASE1
30 Participants

Effects of Psilocybin in Obsessive Compulsive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-28
Completion: 2026-09-12
Conditions
Obsessive-Compulsive Disorder
Interventions
DRUG
No Results Yet
NCT05543681 | RECRUITING | PHASE2
164 Participants

Clinical Trial on Agitation in Alzheimer's Dementia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-11
Completion: 2026-03-30
Conditions
Alzheimer Disease Agitation,Psychomotor Care Giving Burden NPS Aggression
Interventions
DRUG
No Results Yet
NCT05534932 | ACTIVE_NOT_RECRUITING | NA
20 Participants

Guideline-directed Management and Therapy (GDMT) for the Prevention of Postpartum Cardiac Dysfunction in Preeclamptic African American Women

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-27
Completion: 2026-07-01
Conditions
Preeclampsia Postpartum
Interventions
DEVICE
No Results Yet
NCT05532657 | ACTIVE_NOT_RECRUITING | PHASE3
629 Participants

ACHIEVE Brain Health Follow-Up Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-01-12
Completion: 2026-06-30
Conditions
Aging Cognitive Decline Mild Cognitive Impairment Dementia Hearing Loss
Interventions
OTHER
No Results Yet
NCT05523947 | RECRUITING | PHASE1/PHASE2
137 Participants

Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-08-26
Completion: 2026-10-01
Conditions
HER2-Positive Solid Tumor
Interventions
DRUG
No Results Yet
NCT05522075 | RECRUITING | NA
55 Participants

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-21
Completion: 2026-04-30
Conditions
Alcohol Drinking Binge Drinking Blood Pressure Alcohol Abstinence Aging Lifestyle Factors Vasodilation Behavioral Problem
Interventions
BEHAVIORAL
No Results Yet
NCT05509582 | WITHDRAWN | PHASE2
0 Participants

Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-07
Completion: 2025-11-07
Conditions
Immune Mediated Anemia Immune Mediated Thrombocytopenia Chronic GVHD
Interventions
DRUG
No Results Yet
NCT05505110 | RECRUITING | EARLY_PHASE1
20 Participants

MOdification Of THe Early-Life Respiratory Microbiome Through Vaginal SEEDing

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-09
Completion: 2028-08-10
Conditions
C-section Vaginal Seeding Respiratory Microbiome
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05500586 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
21 Participants

The Effects of Glucagon on Hepatic Metabolism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-20
Completion: 2025-09-30
Conditions
Obesity Type2diabetes NAFLD
Interventions
DRUG
No Results Yet
NCT05498428 | RECRUITING | PHASE2
520 Participants

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-11
Completion: 2027-08-17
Conditions
Carcinoma, Non-small-Cell Lung
Interventions
DRUG
No Results Yet
NCT05492942 | COMPLETED | NA
134 Participants

Records for Alcohol Care Enhancement

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-11
Completion: 2024-10-17
Conditions
Alcohol Use Disorder (AUD)
Interventions
BEHAVIORAL
NCT05488314 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
57 Participants

A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-12-13
Completion: 2026-06-09
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
NCT05473598 | ACTIVE_NOT_RECRUITING | NA
234 Participants

Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone Support

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-12-01
Completion: 2025-12-01
Conditions
Alcoholism
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT05466929 | COMPLETED | NA
365 Participants

Engagement With Digital Mental Health (DMH) Technologies in Pediatric Primary Care

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-16
Completion: 2025-11-06
Conditions
Mental Health
Interventions
BEHAVIORAL
No Results Yet
NCT05458219 | RECRUITING | PHASE1
470 Participants

A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-26
Completion: 2027-06-30
Conditions
Locally Advanced Unresectable or Metastatic Solid Tumors
Interventions
DRUG
No Results Yet
NCT05455320 | ACTIVE_NOT_RECRUITING | PHASE3
864 Participants
NCT05453903 | RECRUITING | PHASE1
200 Participants

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-04
Completion: 2026-10-30
Conditions
Leukemia, Myeloid, Acute
Interventions
DRUG
No Results Yet
NCT05452642 | ACTIVE_NOT_RECRUITING | NA
223 Participants

The Supporting Understanding of PCOS Education and Research (SUPER) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-08-15
Completion: 2026-07-15
Conditions
Polycystic Ovary
Interventions
BEHAVIORAL
No Results Yet
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