Clinical Trials

NCT05466929 | COMPLETED | NA

365 Participants

Engagement With Digital Mental Health (DMH) Technologies in Pediatric Primary Care

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-07-16

Completion: 2025-11-06

Conditions

Mental Health

Interventions

BEHAVIORAL

No Results Yet

NCT05458219 | RECRUITING | PHASE1

470 Participants

A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-10-26

Completion: 2027-06-30

Conditions

Locally Advanced Unresectable or Metastatic Solid Tumors

Interventions

DRUG

No Results Yet

NCT05455320 | ACTIVE_NOT_RECRUITING | PHASE3

864 Participants

A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-10-13

Completion: 2026-02-06

Conditions

Relapsed or Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05453903 | RECRUITING | PHASE1

200 Participants

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-10-04

Completion: 2026-10-30

Conditions

Leukemia, Myeloid, Acute

Interventions

DRUG

No Results Yet

NCT05452642 | ACTIVE_NOT_RECRUITING | NA

223 Participants

The Supporting Understanding of PCOS Education and Research (SUPER) Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-08-15

Completion: 2026-07-15

Conditions

Polycystic Ovary

Interventions

BEHAVIORAL

No Results Yet

NCT05451212 | COMPLETED | PHASE1

7 Participants

Open-label Study to Evaluate the Safety of Various Dosing Regimens of MuSK-CAART for MuSK Myasthenia Gravis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-11-23

Completion: 2025-07-24

Conditions

MuSK Myasthenia Gravis

Interventions

BIOLOGICAL

No Results Yet

NCT05438212 | ACTIVE_NOT_RECRUITING | PHASE3

237 Participants

Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-10-24

Completion: 2027-03-16

Conditions

Metastatic Malignant Neoplasm in the Brain

Interventions

PROCEDURE OTHER RADIATION

No Results Yet

NCT05438043 | RECRUITING | PHASE3

500 Participants

A Study of Daratumumab

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-12-15

Completion: 2026-01-30

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05437562 | NOT_YET_RECRUITING | PHASE2

120 Participants

Randomized Clinical Trial for Ewing Amputation in the VA

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-12-01

Completion: 2030-12-01

Conditions

Peripheral Arterial Disease

Interventions

PROCEDURE

No Results Yet

NCT05434234 | RECRUITING | PHASE1/PHASE2

312 Participants

A Study of YL201 in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-05-25

Completion: 2027-04-06

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT05425264 | RECRUITING | NA

80 Participants

Home-Based Exercise Tele-Rehabilitation After COVID-19

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-06-29

Completion: 2027-01-30

Conditions

Post SARS-CoV2 (COVID-19)

Interventions

OTHER

No Results Yet

NCT05424822 | ACTIVE_NOT_RECRUITING | PHASE1

167 Participants

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-08-18

Completion: 2026-06-12

Conditions

Lymphoma, Non-Hodgkin Leukemia, Lymphocytic, Chronic, B-Cell

Interventions

DRUG

No Results Yet

NCT05421663 | RECRUITING | PHASE1/PHASE2

385 Participants

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-08-12

Completion: 2028-12-29

Conditions

Lymphoma, Non-Hodgkin Lymphoma, B-Cell Lymphoma, Large B-Cell, Diffuse

Interventions

BIOLOGICAL

No Results Yet

NCT05419024 | RECRUITING | PHASE2

50 Participants

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-01-09

Completion: 2026-08-01

Conditions

HIV

Interventions

OTHER

No Results Yet

NCT05411198 | RECRUITING | PHASE3

65 Participants

Study to Assess Change in Disease Activity and Adverse Events of Ab Externo Approach for Glaucoma Gel Stent (XEN45) Implantation In Participants Aged 45 Years or Older With Open-Angle Glaucoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-07-22

Completion: 2026-01-31

Conditions

Open-Angle Glaucoma

Interventions

DEVICE

No Results Yet

NCT05408845 | RECRUITING | PHASE2

146 Participants

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-03-03

Completion: 2028-07-31

Conditions

Metastatic Salivary Gland Carcinoma Recurrent Salivary Gland Carcinoma Stage III Major Salivary Gland Cancer AJCC v8 Stage IV Major Salivary Gland Cancer AJCC v8 Unresectable Salivary Gland Carcinoma

Interventions

PROCEDURE DRUG OTHER BIOLOGICAL

No Results Yet

NCT05397470 | TERMINATED | PHASE3

260 Participants

Efficacy and Safety of Losmapimod in Treating Participants With Facioscapulohumeral Muscular Dystrophy (FSHD) (REACH)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-06-16

Completion: 2024-11-19

Conditions

Facioscapulohumeral Muscular Dystrophy (FSHD)

Interventions

DRUG

Results Available

NCT05388669 | ACTIVE_NOT_RECRUITING | PHASE3

418 Participants

A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-08-05

Completion: 2024-01-03

Conditions

Advanced or Metastatic Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05379634 | ACTIVE_NOT_RECRUITING | PHASE2

36 Participants

A Study of Nipocalimab in Participants With Active Idiopathic Inflammatory Myopathies

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-07-05

Completion: 2025-09-04

Conditions

Myositis

Interventions

DRUG OTHER

No Results Yet

NCT05379595 | RECRUITING | PHASE1/PHASE2

225 Participants

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-07-29

Completion: 2027-04-27

Conditions

Advanced or Metastatic Colorectal Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT05371509 | COMPLETED | NA

43 Participants

Novel Myofunctional Water Bottle to Reduce OSA and Snoring Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-09-07

Completion: 2024-12-10

Conditions

Obstructive Sleep Apnea Snoring

Interventions

DEVICE OTHER

Results Available

NCT05359861 | COMPLETED | PHASE2

30 Participants

Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-04-12

Completion: 2025-06-30

Conditions

Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT05347095 | ACTIVE_NOT_RECRUITING | PHASE3

288 Participants

A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-09-27

Completion: 2027-03-25

Conditions

Fistulizing Crohns Disease Perianal Crohns Disease

Interventions

DRUG

No Results Yet

NCT05339061 | RECRUITING | NA

40 Participants

Physician Modified Endograft For Complex Aortic Aneurysm Repair

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-03-01

Completion: 2025-12-31

Conditions

Complex Abdominal Aortic Aneurysm Juxtarenal Aortic Aneurysm Pararenal Aortic Aneurysm Thoracoabdominal Aortic Aneurysm

Interventions

DEVICE

No Results Yet

NCT05338775 | ACTIVE_NOT_RECRUITING | PHASE1

74 Participants

A Study of Talquetamab and Teclistamab Each in Combination With a Programmed Cell Death Receptor-1 (PD-1) Inhibitor for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-05-25

Completion: 2025-05-22

Conditions

Relapsed/ Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05327686 | RECRUITING | PHASE2

240 Participants

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-02-01

Completion: 2028-06-15

Conditions

Metastatic Renal Cell Carcinoma Stage III Renal Cell Cancer AJCC v8 Stage IV Renal Cell Cancer AJCC v8 Unresectable Renal Cell Carcinoma

Interventions

BIOLOGICAL DRUG PROCEDURE RADIATION

No Results Yet

NCT05327114 | RECRUITING | PHASE2/PHASE3

201 Participants

Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-09-23

Completion: 2027-05-14

Conditions

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Interventions

DRUG

No Results Yet

NCT05319730 | RECRUITING | PHASE1/PHASE2

230 Participants

A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-05-16

Completion: 2026-11-07

Conditions

Esophageal Squamous Cell Carcinoma

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT05316311 | RECRUITING | NA

194 Participants

A Study of Implantation of CRENEOUS ENTERPRISE 2 Intracranial Stent in Participants With Severe Symptomatic Intracranial Atherosclerotic Stenosis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-05-24

Completion: 2026-02-10

Conditions

Intracranial Atherosclerosis

Interventions

DEVICE

No Results Yet

NCT05303519 | RECRUITING | PHASE2

125 Participants

Safusidenib Phase 2 Study in IDH1 Mutant Glioma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-06-05

Completion: 2027-12-01

Conditions

Glioma Astrocytoma, Grade IV IDH1-mutant Glioma Astrocytoma, IDH-Mutant, Grade 3 Astrocytoma, IDH-Mutant, Grade 4

Interventions

DRUG

No Results Yet

NCT05296304 | RECRUITING | PHASE1

20 Participants

A Study of Bexarotene Combined With Radiotherapy in People With Mycosis Fungoides

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-16

Completion: 2026-03-31

Conditions

Cutaneous T-cell Lymphoma

Interventions

DRUG RADIATION

No Results Yet

NCT05286801 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

86 Participants

Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-11-17

Completion: 2030-03-31

Conditions

Atypical Teratoid/Rhabdoid Tumor Epithelioid Sarcoma Kidney Medullary Carcinoma Malignant Solid Neoplasm Poorly Differentiated Chordoma Recurrent Atypical Teratoid/Rhabdoid Tumor Recurrent Chordoma Recurrent Epithelioid Sarcoma Recurrent Kidney Medullary Carcinoma Recurrent Malignant Solid Neoplasm Recurrent Rhabdoid Tumor Refractory Atypical Teratoid/Rhabdoid Tumor Refractory Chordoma Refractory Epithelioid Sarcoma Refractory Kidney Medullary Carcinoma Refractory Malignant Solid Neoplasm Refractory Rhabdoid Tumor Rhabdoid Tumor

Interventions

BIOLOGICAL PROCEDURE OTHER

No Results Yet

NCT05278234 | ACTIVE_NOT_RECRUITING | NA

414 Participants

STEPS: An Efficacy Trial of a Chronic Pain Self-Management Program for Older Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-11-29

Completion: 2026-04-01

Conditions

Chronic Pain

Interventions

BEHAVIORAL

No Results Yet

NCT05277051 | RECRUITING | PHASE1

158 Participants

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-22

Completion: 2027-08-31

Conditions

Neoplasms

Interventions

DRUG

No Results Yet

NCT05275868 | TERMINATED | PHASE1

41 Participants

Study of MGY825 in Patients With Advanced Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-10-05

Completion: 2025-10-13

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05272631 | ACTIVE_NOT_RECRUITING

250 Participants

Depuy Synthes Lower Extremity Shaft Nail Registry

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2022-05-04

Completion: 2025-12-31

Conditions

Femoral Fractures Tibial Fractures

Interventions

DEVICE

No Results Yet

NCT05265273 | RECRUITING | PHASE2/PHASE3

12 Participants

A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-07-20

Completion: 2026-06-26

Conditions

Myasthenia Gravis

Interventions

DRUG

No Results Yet

NCT05256641 | RECRUITING | PHASE1/PHASE2

24 Participants

Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-01-23

Completion: 2026-01-31

Conditions

Diffuse Large B-Cell Lymphoma High-grade B-cell Lymphoma Transformed Lymphoma Secondary Central Nervous System Lymphoma

Interventions

DRUG

No Results Yet

NCT05250973 | ACTIVE_NOT_RECRUITING | PHASE2

151 Participants

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-01

Completion: 2025-05-30

Conditions

Amyloidosis

Interventions

DRUG

No Results Yet

NCT05250284 | RECRUITING

400 Participants

The Intersection of Oncology Care and Worker Well-Being

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2022-04-04

Completion: 2026-05-31

Conditions

Solid Tumor

Interventions

BEHAVIORAL

No Results Yet