Clinical Trials

NCT02420847 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

57 Participants

Ixazomib Citrate With Gemcitabine Hydrochloride and Doxorubicin Hydrochloride in Treating Patients With Urothelial Cancer That is Metastatic or Cannot Be Removed by Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2015-07-03

Completion: 2025-12-31

Conditions

Metastatic Urothelial Carcinoma Transitional Cell Carcinoma Unresectable Transitional Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT02381886 | ACTIVE_NOT_RECRUITING | PHASE1

166 Participants

A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2015-03-06

Completion: 2016-12-07

Conditions

Advanced Malignancies That Harbor IDHR132 Mutations

Interventions

DRUG

No Results Yet

NCT02354014 | RECRUITING | PHASE2

60 Participants

Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of Multidrug Resistant Tuberculosis (MDR-TB) Medications for Treatment of Children/Adolescents Pulmonary MDR-TB

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2016-05-03

Completion: 2027-02-11

Conditions

Multidrug-Resistant Tuberculosis

Interventions

DRUG

No Results Yet

NCT02337985 | ACTIVE_NOT_RECRUITING | PHASE1

10 Participants

Gene Therapy and Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2015-11-20

Completion: 2026-09-08

Conditions

AIDS-Related Burkitt Lymphoma AIDS-Related Diffuse Large B-cell Lymphoma AIDS-Related Plasmablastic Lymphoma AIDS-Related Primary Effusion Lymphoma HIV Infection AIDS Related Non-Hodgkin Lymphoma

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT02321501 | ACTIVE_NOT_RECRUITING | PHASE1

37 Participants

Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2016-06-22

Completion: 2026-12-31

Conditions

ALK Positive Locally Advanced Malignant Solid Neoplasm Metastatic Malignant Solid Neoplasm ROS1 Gene Rearrangement Stage IIIB Lung Non-Small Cell Cancer AJCC v7 Stage IV Lung Non-Small Cell Cancer AJCC v7

Interventions

DRUG OTHER

No Results Yet

NCT02311933 | ACTIVE_NOT_RECRUITING | PHASE2

81 Participants

Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2015-05-28

Completion: 2020-11-06

Conditions

Recurrent Breast Carcinoma Stage III Breast Cancer AJCC v7 Stage IIIA Breast Cancer AJCC v7 Stage IIIB Breast Cancer AJCC v7 Stage IIIC Breast Cancer AJCC v7 Stage IV Breast Cancer AJCC v6 and v7

Interventions

DRUG OTHER

Results Available

NCT02280161 | RECRUITING

2000 Participants

Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2014-09-16

Completion: 2026-09-16

Conditions

Malignant Neoplasm

Interventions

OTHER

No Results Yet

NCT02253316 | ACTIVE_NOT_RECRUITING | PHASE2

236 Participants

Phase II Study of IRD (Ixazomib, Lenalidomide, Dexamethasone) Post Autologous Stem Cell Transplantation Followed by Maintenance Ixazomib or Lenalidomide for Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2015-01-20

Completion: 2020-02-05

Conditions

Multiple Myeloma

Interventions

BIOLOGICAL DRUG

Results Available

NCT02210117 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

104 Participants

Nivolumab With or Without Bevacizumab or Ipilimumab Before Surgery in Treating Patients With Metastatic Kidney Cancer That Can Be Removed by Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2014-11-25

Completion: 2025-12-31

Conditions

Clear Cell Renal Cell Carcinoma Metastatic Kidney Carcinoma Stage IV Renal Cell Cancer AJCC v7

Interventions

BIOLOGICAL PROCEDURE OTHER

No Results Yet

NCT02180867 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

140 Participants

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2014-07-11

Completion: 2019-06-30

Conditions

Alveolar Soft Part Sarcoma Angiomatoid Fibrous Histiocytoma Atypical Fibroxanthoma Clear Cell Sarcoma of Soft Tissue Epithelioid Malignant Peripheral Nerve Sheath Tumor Epithelioid Sarcoma Extraskeletal Myxoid Chondrosarcoma Extraskeletal Osteosarcoma Fibrohistiocytic Neoplasm Fibrosarcoma Inflammatory Myofibroblastic Tumor Intimal Sarcoma Leiomyosarcoma Liposarcoma Liver Embryonal Sarcoma Low Grade Fibromyxoid Sarcoma Low Grade Myofibroblastic Sarcoma Malignant Peripheral Nerve Sheath Tumor Malignant Skin Granular Cell Tumor Malignant Triton Tumor Mesenchymal Chondrosarcoma Myxofibrosarcoma Myxoid Chondrosarcoma Myxoinflammatory Fibroblastic Sarcoma Nerve Sheath Neoplasm PEComa Pericytic Neoplasm Plexiform Fibrohistiocytic Tumor Sclerosing Epithelioid Fibrosarcoma Skin Glomus Tumor Stage IB Soft Tissue Sarcoma AJCC v7 Stage IIB Soft Tissue Sarcoma AJCC v7 Stage III Soft Tissue Sarcoma AJCC v7 Stage IV Soft Tissue Sarcoma AJCC v7 Synovial Sarcoma Undifferentiated High Grade Pleomorphic Sarcoma of Bone

Interventions

DRUG RADIATION PROCEDURE

Results Available

NCT02179086 | ACTIVE_NOT_RECRUITING | PHASE2

606 Participants

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2014-12-04

Completion: 2025-12-31

Conditions

Glioblastoma

Interventions

RADIATION OTHER DRUG

No Results Yet

NCT02123758 | ACTIVE_NOT_RECRUITING | PHASE1

57 Participants

A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2014-07-09

Completion: 2016-06-27

Conditions

Prostatic Neoplasms Metastatic Castration-Resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT02107989 | RECRUITING

700 Participants

Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2014-03-11

Completion: 2028-03-30

Conditions

Epilepsy

Interventions

DEVICE

No Results Yet

NCT02003222 | ACTIVE_NOT_RECRUITING | PHASE3

488 Participants

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2014-05-19

Completion: 2023-06-23

Conditions

Acute Lymphoblastic Leukemia B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

Interventions

PROCEDURE BIOLOGICAL DRUG

Results Available

NCT01964859 | RECRUITING | PHASE2

80 Participants

Feasibility Study for Fibroblast Autologous Skin Grafts

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2015-01-07

Completion: 2027-12-02

Conditions

Wounds and Injuries

Interventions

BIOLOGICAL

No Results Yet

NCT01962636 | RECRUITING | NA

200 Participants

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2016-12-31

Completion: 2026-02-28

Conditions

Acute Myeloid Leukemia (AML) Acute Lymphocytic Leukemia (ALL) Chronic Myelogenous Leukemia Plasma Cell Leukemia Myelofibrosis Myelodysplasia Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Marginal Zone B-Cell Lymphoma Follicular Lymphoma Lymphoplasmacytic Lymphoma Mantle-Cell Lymphoma Prolymphocytic Leukemia Diffuse Large B Cell Lymphoma Lymphoblastic Lymphoma Burkitt's Lymphoma Non-Hodgkin Lymphoma Multiple Myeloma

Interventions

DRUG RADIATION BIOLOGICAL

No Results Yet

NCT01955499 | ACTIVE_NOT_RECRUITING | PHASE1

39 Participants

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2013-09-24

Completion: 2024-11-06

Conditions

Recurrent Diffuse Large B-Cell Lymphoma Recurrent Follicular Lymphoma Recurrent Lymphoplasmacytic Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Marginal Zone Lymphoma Refractory Diffuse Large B-Cell Lymphoma Refractory Follicular Lymphoma Refractory Lymphoplasmacytic Lymphoma Refractory Mantle Cell Lymphoma Refractory Marginal Zone Lymphoma

Interventions

PROCEDURE DRUG

No Results Yet

NCT01950390 | ACTIVE_NOT_RECRUITING | PHASE2

169 Participants

Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2014-01-24

Completion: 2021-10-06

Conditions

Stage IIIC Cutaneous Melanoma AJCC v7 Stage IV Cutaneous Melanoma AJCC v6 and v7 Unresectable Melanoma

Interventions

BIOLOGICAL

Results Available

NCT01934660 | COMPLETED

150 Participants

Links Between Inflammation and Cardiometabolic Diseases

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2013-12-02

Completion: 2022-08-03

Conditions

Diabetes Mellitus Cardiovascular Disease Healthy Volunteer Inflammation

Interventions

DRUG

No Results Yet

NCT01909245 | ACTIVE_NOT_RECRUITING | PHASE2

10 Participants

Islet Cell Transplant for Type 1 Diabetes

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2013-10-16

Completion: 2026-09-22

Conditions

Type 1 Diabetes Mellitus

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT01886872 | ACTIVE_NOT_RECRUITING | PHASE3

547 Participants

Rituximab and Bendamustine Hydrochloride, Rituximab and Ibrutinib, or Ibrutinib Alone in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2014-01-15

Completion: 2018-08-07

Conditions

Stage I Chronic Lymphocytic Leukemia Stage II Chronic Lymphocytic Leukemia Stage III Chronic Lymphocytic Leukemia Stage IV Chronic Lymphocytic Leukemia

Interventions

DRUG PROCEDURE OTHER BIOLOGICAL

Results Available

NCT01867411 | COMPLETED

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2011-09-09

Completion: 2018-12-02

Conditions

Breast Cancer

No Results Yet

NCT01453660 | ACTIVE_NOT_RECRUITING

44 Participants

Acute Changes in Endothelial Function in Germ Cell Tumor Patients Treated With Cisplatin and Untreated Germ Cell Tumor Controls

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2011-10-11

Completion: 2026-10-31

Conditions

Germ Cell Cancer

Interventions

OTHER

No Results Yet

NCT01446133 | ACTIVE_NOT_RECRUITING | PHASE2

120 Participants

Combination of Lenalidomide and Rituximab in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL-SLL)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2011-12-12

Completion: 2025-11-30

Conditions

Leukemia Lymphoma

Interventions

DRUG

No Results Yet

NCT01306019 | RECRUITING | PHASE1/PHASE2

40 Participants

Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2012-09-25

Completion: 2032-12-31

Conditions

X-linked Severe Combined Immunodeficiency (XSCID)

Interventions

BIOLOGICAL DRUG

No Results Yet

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2011-01-15

Completion: 2023-02-01

Conditions

Breast Ductal Carcinoma In Situ Invasive Breast Carcinoma Multicentric Breast Carcinoma Multifocal Breast Carcinoma Synchronous Bilateral Breast Carcinoma

Interventions

DRUG OTHER

Results Available