Clinical Trials

NCT04814654 | COMPLETED | NA

1004 Participants

CHALO! 2.0: A Mobile Technology Based Intervention to Accelerate HIV Testing and Linkage to Preventive Treatment.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2022-04-22

Completion: 2024-06-27

Conditions

Hiv

Interventions

BEHAVIORAL

Results Available

NCT04790344 | ACTIVE_NOT_RECRUITING | NA

525 Participants

LUX-Dx TRENDS Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2021-03-20

Completion: 2026-05-31

Conditions

Heart Failure

Interventions

DEVICE

No Results Yet

NCT04755283 | ACTIVE_NOT_RECRUITING | PHASE2

1287 Participants

Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2021-02-02

Completion: 2024-02-15

Conditions

Atrial Fibrillation (AF) Stroke

Interventions

BIOLOGICAL DRUG

Results Available

NCT04748809 | RECRUITING | NA

124 Participants

Effect of Anti-inflammatory Diet in Rheumatoid Arthritis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-11-01

Completion: 2025-11-01

Conditions

Rheumatoid Arthritis

Interventions

OTHER

No Results Yet

NCT04742439 | WITHDRAWN | NA

0 Participants

Individualizing tDCS Dose

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-12-02

Completion: 2024-12-02

Conditions

tDCS Motor Function

Interventions

DEVICE

No Results Yet

NCT04729062 | APPROVED_FOR_MARKETING

C3G/Primary IC-MPGN EAP

Study Type: EXPANDED_ACCESS

Last Updated: 2025-11-06

Conditions

C3G IC-MPGN C3 Glomerulopathy C3 Glomerulonephritis Complement 3 Glomerulopathy Complement 3 Glomerulopathy (C3G) Complement 3 Glomerulonephritis Dense Deposit Disease DDD Membranoproliferative Glomerulonephritis Membranoproliferative Glomerulonephritis (MPGN) Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)

Interventions

DRUG

No Results Yet

NCT04663997 | ACTIVE_NOT_RECRUITING | PHASE2

200 Participants

177 LuPSMA-617 vs Docetaxel in Metastatic Castration Resistant and PSMA-Positive Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2021-08-11

Completion: 2025-08-25

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT04657289 | ACTIVE_NOT_RECRUITING | PHASE3

451 Participants

A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2021-07-14

Completion: 2027-01-07

Conditions

Neovascular Age-related Macular Degeneration (nAMD)

Interventions

DRUG DEVICE

No Results Yet

NCT04655339 | WITHDRAWN | PHASE2/PHASE3

0 Participants

Laparoscopic Transversus Abdominis Plane (TAP) Block to Reduce Post-operative Opioids

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-01-24

Completion: 2021-09-03

Conditions

Opioid Use

Interventions

DRUG

No Results Yet

NCT04626635 | RECRUITING | PHASE1/PHASE2

933 Participants

A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-12-21

Completion: 2026-08-19

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT04624555 | RECRUITING

50 Participants

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2022-10-31

Completion: 2026-01-30

Conditions

Adenocarcinoma of the Colon Adenocarcinoma of the Rectum Stage I Colorectal Cancer Stage II Colorectal Cancer Stage III Colorectal Cancer

No Results Yet

NCT04620603 | ACTIVE_NOT_RECRUITING | PHASE1

5 Participants

Low-Dose-Rate Brachytherapy Combined With Immune Checkpoint Inhibition in Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2021-05-27

Completion: 2024-03-20

Conditions

Cutaneous Malignant Melanoma Renal Cell Cancer Urothelial Cancer of Renal Pelvis

Interventions

RADIATION DRUG

No Results Yet

NCT04584294 | COMPLETED | NA

465 Participants

Patient-Centered Reproductive Decision Support Tool for Women Veterans

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2021-03-01

Completion: 2024-08-30

Conditions

Contraception Contraception Behavior Prepregnancy Health Reproductive Health

Interventions

BEHAVIORAL

Results Available

NCT04565028 | RECRUITING | NA

40 Participants

Functional Outcomes of Cannabis Use (FOCUS) in Veterans With Posttraumatic Stress Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2022-01-26

Completion: 2025-12-30

Conditions

PTSD Cannabis-Related Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT04550845 | RECRUITING | NA

90 Participants

Understanding of Genetics by Men at Risk for Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2023-05-01

Completion: 2027-09-27

Conditions

Prostate Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04544735 | ACTIVE_NOT_RECRUITING | NA

12 Participants

Improving Women's Function After Pelvic Radiation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-10-07

Completion: 2026-05-31

Conditions

Sexual Dysfunction Pelvic Floor Disorders Gynecologic Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04502225 | RECRUITING | NA

44 Participants

Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-08-21

Completion: 2026-08-31

Conditions

Supine Hypertension Autonomic Failure

Interventions

OTHER

No Results Yet

NCT04485013 | RECRUITING | PHASE1

240 Participants

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-07-14

Completion: 2027-06-01

Conditions

Cancer

Interventions

DRUG

No Results Yet

NCT04475926 | ACTIVE_NOT_RECRUITING

205 Participants

A Study of the Natural History of Participants With LGMD2E/R4, LGMD2D/R3, LGMD2C/R5, and LGMD2A/R1 ≥ 4 Years of Age, Who Are Managed in Routine Clinical Practice

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2021-04-22

Completion: 2030-09-05

Conditions

Limb-girdle Muscular Dystrophy

No Results Yet

NCT04464226 | RECRUITING | PHASE3

402 Participants

Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-10-20

Completion: 2028-06-26

Conditions

Cancer

Interventions

DRUG

No Results Yet

NCT04463979 | ACTIVE_NOT_RECRUITING

66 Participants

Perioperative Evaluation of Cerebellar Tumors

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2021-02-28

Completion: 2025-05-16

Conditions

Cerebellar Tumors Brain Tumor

Interventions

OTHER

No Results Yet

NCT04448301 | COMPLETED | NA

81 Participants

PC001- A Study to Evaluate the Usability of PointCheck

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2021-02-09

Completion: 2025-06-30

Conditions

Neoplasms Neutropenia

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04410796 | RECRUITING | PHASE2

571 Participants

Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-05-28

Completion: 2026-05-31

Conditions

Metastatic Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT04336189 | COMPLETED | PHASE3

2757 Participants

Optimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-12-28

Completion: 2024-07-28

Conditions

Malaria

Interventions

DRUG

Results Available

NCT04329065 | RECRUITING | PHASE2

25 Participants

Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2022-04-20

Completion: 2026-08-15

Conditions

Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8

Interventions

BIOLOGICAL DRUG PROCEDURE

No Results Yet

NCT04320888 | ACTIVE_NOT_RECRUITING | PHASE2

1 Participants

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2021-05-03

Completion: 2024-09-30

Conditions

Hematopoietic and Lymphatic System Neoplasm Recurrent Ependymoma Recurrent Ewing Sarcoma Recurrent Hepatoblastoma Recurrent Histiocytic and Dendritic Cell Neoplasm Recurrent Langerhans Cell Histiocytosis Recurrent Lymphoma Recurrent Malignant Germ Cell Tumor Recurrent Malignant Glioma Recurrent Malignant Solid Neoplasm Recurrent Medulloblastoma Recurrent Neuroblastoma Recurrent Non-Hodgkin Lymphoma Recurrent Osteosarcoma Recurrent Peripheral Primitive Neuroectodermal Tumor Recurrent Rhabdoid Tumor Recurrent Rhabdomyosarcoma Recurrent Soft Tissue Sarcoma Recurrent WHO Grade 2 Glioma Refractory Ependymoma Refractory Ewing Sarcoma Refractory Hepatoblastoma Refractory Histiocytic and Dendritic Cell Neoplasm Refractory Langerhans Cell Histiocytosis Refractory Lymphoma Refractory Malignant Germ Cell Tumor Refractory Malignant Glioma Refractory Malignant Solid Neoplasm Refractory Medulloblastoma Refractory Neuroblastoma Refractory Non-Hodgkin Lymphoma Refractory Osteosarcoma Refractory Peripheral Primitive Neuroectodermal Tumor Refractory Rhabdoid Tumor Refractory Rhabdomyosarcoma Refractory Soft Tissue Sarcoma Refractory WHO Grade 2 Glioma Wilms Tumor

Interventions

PROCEDURE DRUG

Results Available

NCT04293341 | COMPLETED | NA

304 Participants

Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-10-01

Completion: 2025-01-01

Conditions

Major Depressive Disorder Posttraumatic Stress Disorder Panic Disorder and Agoraphobia

Interventions

BEHAVIORAL

Results Available

NCT04266093 | ENROLLING_BY_INVITATION

1000 Participants

Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2020-05-08

Completion: 2035-10-01

Conditions

Cervical Intraepithelial Neoplasia Cervical Neoplasms Oropharyngeal Neoplasms Squamous Intraepithelial Lesions of the Cervix Hematologic Malignacies

Interventions

DRUG

No Results Yet

NCT04263597 | COMPLETED | PHASE1/PHASE2

70 Participants

Oral Supplementation of 2'-Fucosyllactose in Allogeneic Bone Marrow Transplant Recipients

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-08-26

Completion: 2025-05-23

Conditions

Hematopoietic Stem Cell Transplant

Interventions

DRUG

No Results Yet

NCT04242498 | COMPLETED | PHASE3

509 Participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-03-02

Completion: 2021-11-09

Conditions

Hidradenitis Suppurativa

Interventions

DRUG OTHER

Results Available

NCT04242446 | COMPLETED | PHASE3

505 Participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-02-19

Completion: 2022-04-07

Conditions

Hidradenitis Suppurativa

Interventions

DRUG OTHER

Results Available

NCT04241341 | ACTIVE_NOT_RECRUITING | PHASE3

180 Participants

Does Immediate Lymphatic Reconstruction Decrease the Risk of Lymphedema After Axillary Lymph Node Dissection

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-01-22

Completion: 2026-01-31

Conditions

Breast Cancer Lymphedema

Interventions

PROCEDURE OTHER

No Results Yet

NCT04228107 | COMPLETED | NA

80 Participants

Treatment Phenotypes for Adolescents With Asthma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-11-16

Completion: 2024-07-14

Conditions

Asthma in Children Adherence, Treatment

Interventions

DEVICE

Results Available

NCT04221477 | ACTIVE_NOT_RECRUITING | PHASE3

271 Participants

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus Nephritis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-08-10

Completion: 2024-08-15

Conditions

Lupus Nephritis

Interventions

DRUG

Results Available

NCT04192591 | ACTIVE_NOT_RECRUITING | NA

166 Participants

A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-01-30

Completion: 2038-02-28

Conditions

Lumbar Spinal Stenosis

Interventions

DEVICE

No Results Yet

NCT04140344 | RECRUITING | NA

224 Participants

The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2023-09-07

Completion: 2026-10-31

Conditions

Lumbar Spine Degeneration Lumbar Spine Instability Lumbar Spondylosis

Interventions

OTHER

No Results Yet

NCT04126200 | ACTIVE_NOT_RECRUITING | PHASE2

208 Participants

Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2019-10-07

Completion: 2025-04-17

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT04090307 | ACTIVE_NOT_RECRUITING | NA

416 Participants

Targeted Lifestyle Change Group Prenatal Care

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2019-11-26

Completion: 2025-12-30

Conditions

Pregnancy Gestational Diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT04075656 | COMPLETED | NA

58 Participants

UrApp for Childhood Nephrotic Syndrome Management (Incident Cohort)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2019-09-17

Completion: 2025-04-25

Conditions

Idiopathic Nephrotic Syndrome

Interventions

BEHAVIORAL

Results Available

NCT04074967 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

70 Participants

Study of ARRY-614 Plus Either Nivolumab or Nivolumab+Ipilimumab

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2020-06-11

Completion: 2024-12-27

Conditions

Renal Cell Carcinoma Melanoma Solid Tumor Non-small Cell Lung Cancer Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet