Clinical Trials

NCT04058990 | ACTIVE_NOT_RECRUITING | NA
180 Participants

Safety and Effectiveness of Agent Paclitaxel-Coated PTCA Balloon Catheter. (AGENT Japan SV)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-12-12
Completion: 2021-12-22
Conditions
Coronary Artery Disease
Interventions
DEVICE
NCT04013854 | ACTIVE_NOT_RECRUITING | PHASE2
67 Participants

Adjuvant Treatment Determined By Pathological Response To Neoadjvuant Nivolumab

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2020-01-01
Completion: 2026-08-31
Conditions
Melanoma Stage III Melanoma
Interventions
DRUG
No Results Yet
NCT03998202 | RECRUITING
300 Participants

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2019-09-23
Completion: 2025-12-31
Conditions
Colorectal Cancer Sarcopenia
No Results Yet
NCT03972657 | RECRUITING | PHASE1/PHASE2
345 Participants

A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-08-12
Completion: 2027-11-15
Conditions
Metastatic Castration-Resistant Prostate Cancer (mCRPC) Clear Cell Renal Cell Carcinoma (ccRCC)
Interventions
DRUG
No Results Yet
NCT03937973 | COMPLETED | NA
139 Participants

Social Experiences and Sleep Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-04-09
Completion: 2025-04-01
Conditions
Sleep Blood Pressure
Interventions
BEHAVIORAL
No Results Yet
NCT03932643 | ACTIVE_NOT_RECRUITING | PHASE1
20 Participants

ONC-201 Maintenance Therapy in Acute Myeloid Leukemia and Myelodysplastic Syndrome After Stem Cell Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-07-30
Completion: 2026-10-31
Conditions
Acute Myeloid Leukemia Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
NCT03882034 | COMPLETED | PHASE3
12 Participants

Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-10-21
Completion: 2025-09-08
Conditions
Pituitary Disease
Interventions
DRUG
No Results Yet
NCT03809533 | ACTIVE_NOT_RECRUITING | PHASE2
30 Participants

The Use of Hepatitis C Positive Kidneys in Hepatitis C Negative Kidney Transplant Recipients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-05-29
Completion: 2026-04-01
Conditions
Kidney Transplantation Hepatitis C
Interventions
DRUG
No Results Yet
NCT03800693 | RECRUITING | PHASE2
60 Participants

2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-03-14
Completion: 2026-08-05
Conditions
Malignant Digestive System Neoplasm
Interventions
DRUG
No Results Yet
NCT03762733 | ENROLLING_BY_INVITATION
500 Participants

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2022-01-04
Completion: 2028-12-29
Conditions
Breast Cancer Ovarian Cancer Uterine Cancer
No Results Yet
NCT03755401 | RECRUITING | NA
75 Participants

Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2018-11-02
Completion: 2027-05-31
Conditions
PTSD
Interventions
OTHER
No Results Yet
NCT03750981 | RECRUITING | NA
500 Participants

C.A.P.A.B.L.E. (CrossFitยฎ and Physical Activity: A Better Life Experience)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2018-11-12
Completion: 2027-11-30
Conditions
Cancer Survivors
Interventions
BEHAVIORAL
No Results Yet
NCT03734653 | COMPLETED | EARLY_PHASE1
30 Participants

Testosterone Therapy in Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-01-18
Completion: 2024-08-14
Conditions
Prostate Cancer Castration-Resistant Prostate Cancer
Interventions
DRUG
No Results Yet
NCT03715335 | COMPLETED | NA
98413 Participants

Adolescent Sexually Transmitted Infection Screening in the Emergency Department

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2020-07-20
Completion: 2022-09-25
Conditions
Gonorrhea Chlamydia
Interventions
OTHER
NCT03710772 | ACTIVE_NOT_RECRUITING | PHASE2
51 Participants

Ibrutinib, Rituximab, Venetoclax, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-05-01
Completion: 2027-03-22
Conditions
Mantle Cell Lymphoma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT03696199 | RECRUITING | PHASE4
70 Participants

Randomized Controlled Trial for Ankle Fracture Pain Control

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2020-09-01
Completion: 2026-09-01
Conditions
Ankle Fractures
Interventions
DRUG
No Results Yet
NCT03631225 | ACTIVE_NOT_RECRUITING
1500 Participants

The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2019-06-25
Completion: 2026-02-01
Conditions
Rheumatoid Arthritis (RA)
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03626857 | COMPLETED | NA
129 Participants

MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-02-22
Completion: 2025-01-09
Conditions
Anterior Cruciate Ligament Injury
Interventions
DEVICE OTHER
No Results Yet
NCT03594630 | RECRUITING | EARLY_PHASE1
120 Participants

Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-03-13
Completion: 2026-10-31
Conditions
Rectal Adenocarcinoma Stage II Rectal Cancer AJCC v8 Stage IIA Rectal Cancer AJCC v8 Stage IIB Rectal Cancer AJCC v8 Stage IIC Rectal Cancer AJCC v8 Stage III Rectal Cancer AJCC v8 Stage IIIA Rectal Cancer AJCC v8 Stage IIIB Rectal Cancer AJCC v8 Stage IIIC Rectal Cancer AJCC v8
Interventions
DRUG OTHER PROCEDURE
No Results Yet
NCT03548454 | COMPLETED | PHASE4
86 Participants

Comparing Effectiveness of Duloxetine and Desipramine in Patients With Chronic Pain: A Pragmatic Trial Using Point of Care Randomization

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2018-09-20
Completion: 2023-12-24
Conditions
Chronic Pain
Interventions
DRUG
NCT03541850 | ACTIVE_NOT_RECRUITING | PHASE2
92 Participants

Stereotactic Body Radiation Therapy in Treating Patients With Localized Prostate Cancer That Have Undergone Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2019-01-29
Completion: 2026-11-01
Conditions
PSA Level Greater Than 0.03 PSA Progression Stage I Prostate Adenocarcinoma AJCC (American Joint Committee on Cancer ) v7 Stage II Prostate Adenocarcinoma AJCC v7 Stage III Prostate Adenocarcinoma AJCC v7
Interventions
DRUG OTHER RADIATION
No Results Yet
NCT03504163 | ACTIVE_NOT_RECRUITING | PHASE2
45 Participants

Pembrolizumab (MK-3475) and Bacillus Calmette-Guรฉrin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2018-06-27
Completion: 2026-04-30
Conditions
Bladder Cancer
Interventions
DRUG
No Results Yet
NCT03312556 | RECRUITING | NA
12 Participants

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2017-09-21
Completion: 2026-09-21
Conditions
Supine Hypertension Autonomic Failure
Interventions
DEVICE DRUG
No Results Yet
NCT03213704 | ACTIVE_NOT_RECRUITING | PHASE2
9 Participants

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2017-08-23
Completion: 2024-09-30
Conditions
Advanced Malignant Solid Neoplasm Recurrent Ependymoma Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor Recurrent Glioma Recurrent Hepatoblastoma Recurrent Kidney Wilms Tumor Recurrent Langerhans Cell Histiocytosis Recurrent Malignant Germ Cell Tumor Recurrent Malignant Glioma Recurrent Malignant Solid Neoplasm Recurrent Medulloblastoma Recurrent Neuroblastoma Recurrent Non-Hodgkin Lymphoma Recurrent Osteosarcoma Recurrent Rhabdoid Tumor Recurrent Rhabdomyosarcoma Recurrent Soft Tissue Sarcoma Refractory Ependymoma Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor Refractory Glioma Refractory Hepatoblastoma Refractory Langerhans Cell Histiocytosis Refractory Malignant Germ Cell Tumor Refractory Malignant Glioma Refractory Malignant Solid Neoplasm Refractory Medulloblastoma Refractory Neuroblastoma Refractory Non-Hodgkin Lymphoma Refractory Osteosarcoma Refractory Primary Central Nervous System Neoplasm Refractory Rhabdoid Tumor Refractory Rhabdomyosarcoma Refractory Soft Tissue Sarcoma
Interventions
PROCEDURE DRUG
NCT03173976 | ACTIVE_NOT_RECRUITING | PHASE1
17 Participants

Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2017-07-18
Completion: 2023-04-20
Conditions
Chondrosarcoma
Interventions
DRUG
No Results Yet
NCT03033043 | ACTIVE_NOT_RECRUITING | NA
56 Participants

Study of the RelayPro Thoracic Stent-Graft in Subjects With an Acute, Complicated Type B Aortic Dissection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2017-12-14
Completion: 2021-10-31
Conditions
Aortic Dissection Type B
Interventions
DEVICE
No Results Yet
NCT02951130 | COMPLETED | PHASE2
66 Participants

Milrinone in Congenital Diaphragmatic Hernia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2017-10-24
Completion: 2024-09-30
Conditions
Congenital Diaphragmatic Hernia Persistent Pulmonary Hypertension of the Newborn Hypoxemic Respiratory Failure Pulmonary Hypoplasia
Interventions
DRUG
NCT02877303 | RECRUITING | PHASE2
80 Participants

Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2016-11-01
Completion: 2026-11-01
Conditions
B Acute Lymphoblastic Leukemia B Lymphoblastic Lymphoma
Interventions
BIOLOGICAL DRUG OTHER
No Results Yet
NCT02842203 | ACTIVE_NOT_RECRUITING
137 Participants

Use of ctDNA for Monitoring of Stage III Colorectal Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2016-09-30
Completion: 2026-09-30
Conditions
Stage III Colorectal Cancer
No Results Yet
NCT02825654 | ENROLLING_BY_INVITATION
6200 Participants

Service and Health Among Deployed Veterans

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2018-03-08
Completion: 2027-06-30
Conditions
Pulmonary Function
No Results Yet
NCT02727803 | RECRUITING | PHASE2
100 Participants

Personalized NK Cell Therapy in CBT

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2016-05-19
Completion: 2027-05-31
Conditions
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive Acute Biphenotypic Leukemia Acute Lymphoblastic Leukemia Acute Lymphoblastic Leukemia in Remission Acute Myeloid Leukemia With Myelodysplasia-Related Changes Acute Myeloid Leukemia With Variant MLL Translocations B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 Chemotherapy-Related Leukemia Chronic Myelomonocytic Leukemia Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements ISS Stage II Plasma Cell Myeloma ISS Stage III Plasma Cell Myeloma Myelodysplastic Syndrome Myelodysplastic Syndrome With Excess Blasts Myelodysplastic Syndrome With Gene Mutation Myelodysplastic/Myeloproliferative Neoplasm Previously Treated Myelodysplastic Syndrome Recurrent Acute Myeloid Leukemia Recurrent Adult Acute Myeloid Leukemia Recurrent Hodgkin Lymphoma Recurrent Non-Hodgkin Lymphoma Refractory Acute Lymphoblastic Leukemia Refractory Adult Acute Lymphoblastic Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Myelodysplastic Syndrome
Interventions
BIOLOGICAL DRUG OTHER RADIATION PROCEDURE
No Results Yet
NCT02716246 | RECRUITING | PHASE2/PHASE3
36 Participants

Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2016-04-25
Completion: 2027-07-31
Conditions
MPS IIIA Sanfilippo Syndrome Sanfilippo A Mucopolysaccharidosis III
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT02684162 | COMPLETED | PHASE2
55 Participants

Guadecitabine and Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapsing After Allogeneic Stem Cell Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2016-06-22
Completion: 2024-10-08
Conditions
Acute Myeloid Leukemia Chronic Myelomonocytic Leukemia Myelodysplastic Syndrome Recurrent Acute Myeloid Leukemia Recurrent Myelodysplastic Syndrome
Interventions
BIOLOGICAL DRUG OTHER
NCT02616302 | RECRUITING | PHASE2
70 Participants

A Study to Check the Safety of Dexlansoprazole and Learn if it Can Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children 2 to 11 Years Old

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-02-20
Completion: 2027-10-31
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
DRUG
No Results Yet
NCT02615184 | RECRUITING | PHASE2
76 Participants

A Study to Check the Safety of Dexlansoprazole and Learn If it Can Heal Erosive Esophagitis (EE) and Keep it Healed in Children 2 to 11 Years Old

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-05-23
Completion: 2027-10-31
Conditions
Erosive Esophagitis
Interventions
DRUG
No Results Yet
NCT02603341 | ACTIVE_NOT_RECRUITING | NA
1238 Participants

Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2016-04-06
Completion: 2036-11-30
Conditions
Breast Cancer
Interventions
RADIATION
No Results Yet
NCT02593175 | COMPLETED | PHASE2
43 Participants

Women's MoonShot: Neoadjuvant Treatment With PaCT for Patients With Locally Advanced TNBC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2016-11-03
Completion: 2025-04-03
Conditions
Stage I Breast Cancer AJCC v7 Stage IA Breast Cancer AJCC v7 Stage IB Breast Cancer AJCC v7 Stage II Breast Cancer AJCC v6 and v7 Stage IIA Breast Cancer AJCC v6 and v7 Stage IIB Breast Cancer AJCC v6 and v7 Stage III Breast Cancer AJCC v7 Stage IIIA Breast Cancer AJCC v7 Stage IIIB Breast Cancer AJCC v7 Stage IIIC Breast Cancer AJCC v7 Triple-Negative Breast Carcinoma
Interventions
DRUG BIOLOGICAL
NCT02451982 | ACTIVE_NOT_RECRUITING | PHASE2
76 Participants

Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2016-03-28
Completion: 2026-05-31
Conditions
Pancreatic Cancer
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT02421380 | RECRUITING | NA
109 Participants

Characterization of Hyperpolarized Pyruvate MRI Reproducibility

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2015-04-30
Completion: 2026-04-30
Conditions
Malignant Solid Tumors
Interventions
DRUG
No Results Yet
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