Clinical Trials

Showing trials with last updates posted in 2024.

NCT04654650 | RECRUITING
5000 Participants

Prospective Registry and Biobank for Long-term Observational Studies in Adult Patients with Pulmonary Hypertension

Study Type: OBSERVATIONAL
Last Updated: 2024-12-20
Start Date: 2021-01-26
Completion: 2041-01-25
Conditions
Pulmonary Hypertension
No Results Yet
NCT04610853 | COMPLETED
100 Participants

Rotational Thromboelastometry Versus DIC Score in Sepsis

Study Type: OBSERVATIONAL
Last Updated: 2024-12-20
Start Date: 2020-11-02
Completion: 2024-03-31
Conditions
Sepsis Septic Shock
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04605965 | ACTIVE_NOT_RECRUITING
200 Participants

WEAICOR: Wearables to Investigate the Long Term Cardiovascular and Behavioral Impacts of COVID-19

Study Type: OBSERVATIONAL
Last Updated: 2024-12-20
Start Date: 2020-06-09
Completion: 2025-09-30
Conditions
Covid19 Cardiovascular Complication Behavioral Changes
No Results Yet
NCT04600323 | COMPLETED | EARLY_PHASE1
34 Participants

Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2021-02-01
Completion: 2023-08-30
Conditions
Metabolic Acidosis Chronic Kidney Disease Cognitive Dysfunction
Interventions
DRUG
NCT04599569 | COMPLETED
100 Participants

Influence of Renal Replacement TherApy on Indirect Calorimetry

Study Type: OBSERVATIONAL
Last Updated: 2024-12-20
Start Date: 2020-10-20
Completion: 2024-05-31
Conditions
Acute Renal Failure Mechanical Ventilation
Interventions
DEVICE
No Results Yet
NCT04559334 | SUSPENDED | NA
15 Participants

Compassionate-Use of 4% T-EDTA Lock Solution for Central Venous Lines of Pediatric PN Patients

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-12-21
Completion: 2025-12-31
Conditions
Central Line Complication Central Line-associated Bloodstream Infection (CLABSI)
Interventions
DEVICE
No Results Yet
NCT04549168 | COMPLETED | PHASE3
194 Participants

A Study of Lemborexant in Chinese Participants With Insomnia Disorder

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-11-06
Completion: 2023-03-17
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
DRUG
NCT04547413 | COMPLETED | NA
155 Participants

STI/HIV Intervention Behavioral Intervention Program

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-11-04
Completion: 2024-03-10
Conditions
Sexually Transmitted Infections
Interventions
BEHAVIORAL
No Results Yet
NCT04541706 | COMPLETED | PHASE4
100 Participants

Lorlatinib in ALK Inhibitor Treated Unresectable Advanced/Recurrent ALK-Positive Non Small Cell Lung Cancer Patients in India

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-08-27
Completion: 2022-07-20
Conditions
Advanced Non-Small Cell Lung Cancer
Interventions
DRUG
NCT04534218 | COMPLETED | PHASE2
49 Participants

Regorafenib in Combination With Metronomic Chemotherapies, and Low-dose Aspirin in Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-10-16
Completion: 2023-12-13
Conditions
Colo-rectal Cancer Metastatic Cancer
Interventions
DRUG
No Results Yet
NCT04528173 | TERMINATED | PHASE4
35 Participants

Opioid-Free Anesthetic for Tonsillectomy

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-07-22
Completion: 2023-08-22
Conditions
Anesthesia Opioid Use Tonsillitis Sleep Disorder Surgery
Interventions
DRUG
NCT04509102 | ENROLLING_BY_INVITATION | EARLY_PHASE1
30 Participants

Psychostimulant Augmentation of Repetitive TMS for the Treatment of Major Depressive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2021-09-27
Completion: 2027-12-01
Conditions
Major Depressive Disorder
Interventions
DRUG
No Results Yet
NCT04492722 | TERMINATED | PHASE2
613 Participants

A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-10-01
Completion: 2022-09-06
Conditions
Chronic Kidney Disease
Interventions
DRUG
NCT04418232 | COMPLETED | PHASE1
243 Participants

Feasibility of a Systems Approach for Alzheimer's Services Among Latinos Attending Primary Care Practices

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2022-05-01
Completion: 2024-08-20
Conditions
Dementia
Interventions
COMBINATION_PRODUCT
NCT04410042 | TERMINATED | PHASE3
15 Participants

Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2021-01-29
Completion: 2024-01-16
Conditions
Cancer of the Bone Limb Salvage
Interventions
DRUG OTHER
NCT04404569 | TERMINATED | PHASE1
5 Participants

Continued Treatment for Participants Enrolled in Studies of BXQ-350

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-06-08
Completion: 2024-09-23
Conditions
Neoplasms
Interventions
DRUG
No Results Yet
NCT04364048 | TERMINATED | PHASE2
10 Participants

Durvalumab Followed by Chemoradiation and Consolidation Durvalumab for Stage III Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-06-18
Completion: 2023-06-20
Conditions
Lung Cancer Non-small Cell Carcinoma
Interventions
DRUG RADIATION
NCT04329975 | COMPLETED
1087 Participants

Specified Drug Use-results Survey (Long-term Use) on MINIRINMELT® OD Tablet (Nocturia)

Study Type: OBSERVATIONAL
Last Updated: 2024-12-20
Start Date: 2020-05-19
Completion: 2024-09-25
Conditions
Nocturia Due to Nocturnal Polyuria
Interventions
DRUG
No Results Yet
NCT04313712 | ACTIVE_NOT_RECRUITING
30 Participants

Pre-post Evaluation of the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans With Repeated Blast Exposure

Study Type: OBSERVATIONAL
Last Updated: 2024-12-20
Start Date: 2021-11-15
Completion: 2025-02-28
Conditions
Blast or Combat Exposure Head Injury Trauma
Interventions
DRUG
No Results Yet
NCT04302493 | COMPLETED | NA
30 Participants

Mindfulness Based Stress Reduction and Post-Stroke Cognition

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2021-01-01
Completion: 2023-06-01
Conditions
Stroke Stroke Sequelae Depression Cognitive Impairment
Interventions
BEHAVIORAL
NCT04273555 | RECRUITING | PHASE1/PHASE2
20 Participants

Monitoring Early Response to Targeted Therapy in Stage IV HER2+ Breast Cancer Patients with Advanced PET/MR Imaging

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2026-03-01
Completion: 2028-06-30
Conditions
HER2-positive Breast Cancer
Interventions
DRUG
No Results Yet
NCT04259580 | RECRUITING
6000 Participants

Calgary Registry for Advanced and Therapeutic Endoscopy

Study Type: OBSERVATIONAL
Last Updated: 2024-12-20
Start Date: 2018-09-01
Completion: 2027-12-31
Conditions
Biliary Disease Pancreatic Diseases
Interventions
PROCEDURE
No Results Yet
NCT04246112 | COMPLETED | NA
12 Participants

A Handwriting Intervention Program for Children With Tic Disorders

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2021-01-12
Completion: 2023-12-18
Conditions
Tourette Syndrome Tic Disorders
Interventions
OTHER
No Results Yet
NCT04218708 | COMPLETED | NA
64 Participants

Electronic Cigarettes as a Harm Reduction Strategy Among People Living With HIV/AIDS

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2021-06-17
Completion: 2023-12-15
Conditions
Nicotine Addiction
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT04214184 | RECRUITING | NA
46 Participants

Biomarkers of Increased Free Living Sleep Time

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2019-12-02
Completion: 2025-10-30
Conditions
Sleep Deprivation Insufficient Sleep Syndrome Sleep Wake Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT04185532 | TERMINATED | NA
44 Participants

Treatment of Acute ACL Injuries in Young Patients Using a Rebound ACL Brace

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-01-08
Completion: 2024-12-17
Conditions
Anterior Cruciate Ligament Injuries Anterior Cruciate Ligament Rupture Anterior Cruciate Ligament Tear
Interventions
OTHER
No Results Yet
NCT04167761 | COMPLETED | EARLY_PHASE1
61 Participants

Ertugliflozin: Cardioprotective Effects on Epicardial Fat

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-07-01
Completion: 2023-12-31
Conditions
Cardiovascular Diseases Atherosclerosis Type 2 Diabetes Insulin Resistance
Interventions
DRUG
No Results Yet
NCT04107857 | COMPLETED
1000000 Participants

Electronic Health Record-Enabled Evidence-Based Smoking Cessation Quality Improvement Implementation Program

Study Type: OBSERVATIONAL
Last Updated: 2024-12-20
Start Date: 2019-10-02
Completion: 2020-04-02
Conditions
Smoking Cessation
Interventions
BEHAVIORAL
No Results Yet
NCT04078152 | COMPLETED | PHASE4
163 Participants

Durvalumab Long-Term Safety and Efficacy Study

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2019-09-05
Completion: 2022-10-31
Conditions
Solid Tumor
Interventions
DRUG
NCT04063267 | COMPLETED | PHASE2
48 Participants

Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-10-27
Completion: 2024-06-01
Conditions
Cigarette Smoking Addiction E Cig Use
Interventions
OTHER
No Results Yet
NCT04059185 | COMPLETED | NA
1133 Participants

Longitudinal Follow-up of Brief Parenting Interventions to Reduce Risk of Child Physical Maltreatment

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2014-11-05
Completion: 2022-11-21
Conditions
Parenting Child Behavior Child Rearing
Interventions
OTHER
NCT04029688 | TERMINATED | PHASE1/PHASE2
38 Participants

A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-01-27
Completion: 2024-05-06
Conditions
Acute Myeloid Leukemia (AML) Acute Lymphoblastic Leukemia (ALL) Neuroblastoma Solid Tumors
Interventions
DRUG
NCT04006106 | COMPLETED
103 Participants

Defining ENDOtypes in Perioperative Hypersensitivity by Extensive Cellular and Molecular PHENotyping (ENDOPHEN)

Study Type: OBSERVATIONAL
Last Updated: 2024-12-20
Start Date: 2020-10-06
Completion: 2022-10-06
Conditions
Perioperative Complication Hypersensitivity
No Results Yet
NCT03992430 | ACTIVE_NOT_RECRUITING | PHASE3
160 Participants

A Study to Compare Safety and Efficacy of High Doses of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-07-13
Completion: 2026-10-31
Conditions
Muscular Dystrophy, Duchenne
Interventions
DRUG
No Results Yet
NCT03984201 | WITHDRAWN | NA
0 Participants

Accelerated Theta Burst in Chronic Pain: A Biomarker Study

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2023-06-01
Completion: 2024-08-01
Conditions
Chronic Pain
Interventions
DEVICE
No Results Yet
NCT03946358 | COMPLETED | PHASE2
47 Participants

Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2020-02-18
Completion: 2024-03-01
Conditions
Squamous Cell Carcinoma of the Head and Neck Anal Canal Cancer Cervical Cancer
Interventions
BIOLOGICAL PROCEDURE OTHER DRUG
No Results Yet
NCT03901534 | TERMINATED | NA
2021 Participants

Assessment of Continuous Positive Airway Pressure Therapy in OSA and ILD

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2023-01-01
Completion: 2023-10-16
Conditions
Interstitial Lung Disease Obstructive Sleep Apnea
Interventions
DEVICE
NCT03886766 | COMPLETED | NA
16 Participants

Bioavailability Mechanistic Study of Hot-Melt Extruded Amorphous Solid Dispersions

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2019-04-30
Completion: 2020-03-19
Conditions
Biological Availability Amorphous Solid Dispersions
Interventions
DRUG
No Results Yet
NCT03875573 | ACTIVE_NOT_RECRUITING | PHASE2
147 Participants

Neo-adjuvant Chemotherapy Combined With Stereotactic Body Radiotherapy to the Primary Tumour +/- Durvalumab, +/- Oleclumab in Luminal B Breast Cancer:

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2019-11-06
Completion: 2025-05-30
Conditions
Luminal B
Interventions
DRUG RADIATION
No Results Yet
NCT03866525 | RECRUITING | PHASE1/PHASE2
300 Participants

OH2 Oncolytic Viral Therapy in Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2024-12-20
Start Date: 2019-04-02
Completion: 2025-08-30
Conditions
Solid Tumor Gastrointestinal Cancer
Interventions
BIOLOGICAL
No Results Yet
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