Clinical Trials

Showing trials with last updates posted in 2023.

NCT04439006 | COMPLETED | PHASE1
10 Participants

Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2020-10-23
Completion: 2022-09-20
Conditions
Aplastic Anemia Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm Monoclonal B-Cell Lymphocytosis Monoclonal Gammopathy of Undetermined Significance Myelodysplastic Syndrome Symptomatic COVID-19 Infection Laboratory-Confirmed
Interventions
OTHER DRUG
No Results Yet
NCT04422249 | RECRUITING | NA
95 Participants

A Study of Laparoscopic Middle Hepatic Vein Guidance and Traditional Anatomic Hemihepatectomy

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-12-23
Completion: 2023-12-23
Conditions
Hepatocellular Carcinoma
Interventions
PROCEDURE
No Results Yet
NCT04375982 | ACTIVE_NOT_RECRUITING | NA
200 Participants

Evaluation of the LumiraDx Point of Care D-Dimer and CRP Tests

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2020-04-20
Completion: 2022-04-05
Conditions
Embolism and Thrombosis Infection Inflammation
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04363359 | COMPLETED | PHASE2
1980 Participants

Clinical Trial of Quadrivalent Influenza Virus Split Vaccine

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2020-01-15
Completion: 2021-09-14
Conditions
Influenza
Interventions
BIOLOGICAL
No Results Yet
NCT04271384 | COMPLETED | PHASE2
25 Participants

Stereotactic Ablative Radiotherapy With Nivolumab for Early-Stage Operable Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2020-02-12
Completion: 2023-11-15
Conditions
Non-small Cell Lung Cancer Stage I
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT04244487 | COMPLETED | NA
88 Participants

Laparoscopic Splenectomy and Azygoportal Disconnection With Intraoperative Endoscopic Variceal Ligation

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2020-01-03
Completion: 2021-12-31
Conditions
Cirrhosis Hypertension Splenectomy Laparoscopy
Interventions
PROCEDURE
No Results Yet
NCT04223960 | COMPLETED | PHASE1
184 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Bioavailability, and Food-effects of EA1080 in Healthy Caucasian and Japanese Male Participants

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2020-01-09
Completion: 2023-08-06
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT04221373 | COMPLETED | NA
32 Participants

Exoskeletal-Assisted Walking in SCI Acute Inpatient Rehabilitation

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-09-30
Completion: 2022-09-13
Conditions
Spinal Cord Injuries Inpatient
Interventions
DEVICE OTHER
NCT04208685 | ACTIVE_NOT_RECRUITING
202 Participants

Evaluating Cognitive Outcomes in Down Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2023-12-26
Start Date: 2018-06-18
Completion: 2024-06-30
Conditions
Down Syndrome
No Results Yet
NCT04177212 | COMPLETED | NA
117 Participants

Investigation of the Effectiveness and Safety of MRZF111 in the Treatment of Décolleté Wrinkles

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-12-04
Completion: 2020-11-17
Conditions
Décolleté Wrinkles
Interventions
DEVICE
NCT04157920 | COMPLETED | NA
78 Participants

Impact of Predilatation Between Self-expanding Valves

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-09-17
Completion: 2021-04-01
Conditions
Aortic Stenosis
Interventions
DEVICE
No Results Yet
NCT04151095 | COMPLETED | NA
19 Participants

Examining The Effect of Blood Flow Restricted Aerobic Training on Mitochondrial Adaptations in Young Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-05-06
Completion: 2019-12-13
Conditions
Mitochondrial Biogenesis
Interventions
OTHER
No Results Yet
NCT04110392 | COMPLETED | NA
30 Participants

Effect of Consumption of Chaya on Lipid Concentration and Antioxidant Status of Patients With Dyslipidemia

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-06-01
Completion: 2020-09-20
Conditions
Dyslipidemias
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT04099836 | TERMINATED | PHASE2
7 Participants

Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2020-07-09
Completion: 2022-11-13
Conditions
Non Small Cell Lung Cancer
Interventions
DRUG
NCT04094012 | COMPLETED | PHASE3
490 Participants

Risk of SDRs Under 3HP and 1HP Regimen for LTBI

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-09-24
Completion: 2023-10-08
Conditions
Latent Tuberculosis Infection
Interventions
DRUG
No Results Yet
NCT04081649 | RECRUITING
95 Participants

Cerebral Oxygenation and Neurological Functioning After Cardiac Surgery

Study Type: OBSERVATIONAL
Last Updated: 2023-12-26
Start Date: 2014-06-01
Completion: 2024-06-30
Conditions
Coronary Artery Disease Cognitive Impairment Delirium
No Results Yet
NCT03978429 | COMPLETED | NA
3000 Participants

An mHealth Strategy to Reduce Pre-Eclampsia and Infant Death in Tanzania

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-08-31
Completion: 2020-04-01
Conditions
Pre-Eclampsia Eclampsia Hypertension, Pregnancy-Induced
Interventions
OTHER
No Results Yet
NCT03946072 | COMPLETED | NA
153 Participants

Transseptal vs Retrograde Aortic Ventricular Entry to Reduce Systemic Emboli

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-07-02
Completion: 2023-11-25
Conditions
Neurocognitive Dysfunction
Interventions
PROCEDURE
No Results Yet
NCT03912831 | TERMINATED | PHASE1
8 Participants

Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-04-30
Completion: 2022-02-18
Conditions
Human Papillomavirus (HPV) 16+ Relapsed/Refractory Cancer
Interventions
DRUG
NCT03879655 | TERMINATED | PHASE2/PHASE3
2 Participants

Open-label Study of VTS-270 in Participants With Neurologic Manifestations of Niemann-Pick Type C1

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-12-02
Completion: 2021-10-18
Conditions
Niemann-Pick Disease, Type C
Interventions
DRUG
NCT03836859 | COMPLETED | PHASE1
30 Participants

Study to Evaluate Safety, Tolerability & PK of rhNGF in Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2018-03-30
Completion: 2018-06-01
Conditions
Healthy Volunteers
Interventions
DRUG OTHER
NCT03675152 | ACTIVE_NOT_RECRUITING | NA
60 Participants

Treatment of Spondylolysisin Pediatric Patients.

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2016-06-12
Completion: 2022-01-30
Conditions
Low Back Pain Stress Fracture
Interventions
OTHER
No Results Yet
NCT03538275 | COMPLETED
80 Participants

Chronobiology and Depression: Circadian Analytics as a Biomarker for Depressive Subtypes

Study Type: OBSERVATIONAL
Last Updated: 2023-12-26
Start Date: 2018-03-13
Completion: 2019-12-31
Conditions
Depression, Bipolar Depression, Unipolar Healthy
Interventions
OTHER
No Results Yet
NCT03512470 | COMPLETED | NA
100 Participants

Clinical Study on the Prevention of Surgical Wound Complications for Aneurysmal Thoracic-abdominal Aortic Pathology Using the "PREVENA" System

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2018-04-24
Completion: 2023-11-30
Conditions
Toraco Abdominal Aneurysm
Interventions
DEVICE OTHER
No Results Yet
NCT03495453 | COMPLETED | NA
94 Participants

Directional Versus Orbital Atherectomy Plaque Modification and Luminal Area Assessment of the Femoro-popliteal Artery Via Intravascular Ultrasound

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2018-03-23
Completion: 2023-08-21
Conditions
Peripheral Artery Disease
Interventions
DEVICE
NCT03433183 | COMPLETED | PHASE2
21 Participants

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-10-02
Completion: 2022-06-22
Conditions
Malignant Peripheral Nerve Sheath Tumors Neurofibromatosis 1
Interventions
DRUG
No Results Yet
NCT03377881 | ACTIVE_NOT_RECRUITING | NA
12750 Participants

Prostate Cancer Detection Using the Stockholm3 Test and MR/Fusion Biopsies

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2018-04-04
Completion: 2020-12-10
Conditions
Prostate Cancer
Interventions
PROCEDURE
No Results Yet
NCT03256981 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
113 Participants

Stereotactic Body Radiotherapy for the Treatment of OPD

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2017-11-27
Completion: 2023-07-17
Conditions
NSCLC
Interventions
RADIATION DRUG
No Results Yet
NCT03212794 | COMPLETED | NA
29 Participants

Initiating Substance Use Disorder Treatment for Hospitalized Opioid Use Disorder Patients.

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2019-02-11
Completion: 2021-12-30
Conditions
Opioid-use Disorder
Interventions
BEHAVIORAL
NCT03194958 | COMPLETED | NA
1944 Participants

Helping Poor Smokers Quit

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2017-06-05
Completion: 2022-07-01
Conditions
Smoking Cessation Smoking, Tobacco Smoking, Cigarette Smoking, Pipe Smoking (Tobacco) Addiction Smoking Tobacco Use Tobacco Dependence Tobacco Use Cessation Tobacco Smoking Tobacco; Use, Rehabilitation Nicotine Dependence Nicotine Use Disorder Nicotine Dependence, Cigarettes Nicotine Dependence Tobacco Product
Interventions
BEHAVIORAL
NCT03141619 | RECRUITING
500 Participants

Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness-2

Study Type: OBSERVATIONAL
Last Updated: 2023-12-26
Start Date: 2017-10-13
Completion: 2024-06-30
Conditions
Critical Illness Respiratory Failure Shock Delirium
No Results Yet
NCT03123783 | COMPLETED | PHASE1/PHASE2
140 Participants

CD40 Agonistic Antibody APX005M (Sotigalimab) in Combination With Nivolumab

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2017-07-10
Completion: 2020-11-16
Conditions
Cancer Non Small Cell Lung Cancer Metastatic Metastatic Melanoma Neoplasm of Lung Melanoma
Interventions
DRUG
NCT02943408 | COMPLETED | NA
48 Participants

Development of a Patient Centered Mental Health Intervention for Recent Veterans

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2017-07-31
Completion: 2022-01-01
Conditions
Stress Disorders, Post-Traumatic Depression Anxiety Substance-Related Disorders
Interventions
BEHAVIORAL
NCT02940041 | TERMINATED
15 Participants

Concordance Between Sonography Amd MRI for Presurgical Diagnosis of Uterine Mesenchymal Malignant Tumors

Study Type: OBSERVATIONAL
Last Updated: 2023-12-26
Start Date: 2016-09-30
Completion: 2017-09-30
Conditions
Leiomyoma Leiomyosarcoma
Interventions
PROCEDURE
No Results Yet
NCT02913274 | TERMINATED | NA
115 Participants

Arteriovenous Fistulae: Drug-eluting Balloon Angioplasty

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2017-03-20
Completion: 2020-04-21
Conditions
Stenosis of Arteriovenous Dialysis Fistula
Interventions
DEVICE
No Results Yet
NCT02710786 | RECRUITING
25000 Participants

Comorbidity After Gastric Bypass

Study Type: OBSERVATIONAL
Last Updated: 2023-12-26
Start Date: 2007-05-31
Completion: 2025-01-31
Conditions
Severe Obesity
Interventions
PROCEDURE
No Results Yet
NCT02687464 | COMPLETED | NA
978 Participants

Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2016-01-20
Completion: 2023-03-02
Conditions
Appendicitis
Interventions
OTHER PROCEDURE
No Results Yet
NCT02600897 | COMPLETED | PHASE1/PHASE2
114 Participants

A Study of Obinutuzumab, Polatuzumab Vedotin, and Lenalidomide in Relapsed or Refractory Follicular Lymphoma (FL) and Rituximab in Combination With Polatuzumab Vedotin and Lenalidomide in Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2016-03-24
Completion: 2021-12-15
Conditions
Relapsed or Refractory Follicular Lymphoma, Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Interventions
DRUG
NCT02399215 | COMPLETED | PHASE2
32 Participants

Nintedanib in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

Study Type: INTERVENTIONAL
Last Updated: 2023-12-26
Start Date: 2015-05-15
Completion: 2019-09-01
Conditions
Carcinoid Tumor Metastatic Carcinoid Tumor Neuroendocrine Neoplasm
Interventions
OTHER DRUG
NCT02299037 | ACTIVE_NOT_RECRUITING
316 Participants

Predicting the Risk of Post-operative Delirium: Use of Neuropsychology, Serum and CSF Biomarkers and Genetics to Predict Risk of Post-operative Delirium

Study Type: OBSERVATIONAL
Last Updated: 2023-12-26
Start Date: 2012-03-31
Completion: 2015-02-28
Conditions
Delirium
No Results Yet
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