Clinical Trials

Showing trials with last updates posted in 2023.

NCT04809259 | NOT_YET_RECRUITING | EARLY_PHASE1
30 Participants

Ambulatory Administration of Meropenem With Elastomeric Pumps and an Isothermal Pouch

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2024-01-01
Completion: 2024-12-31
Conditions
Infection, Bacterial
Interventions
DEVICE
No Results Yet
NCT04803123 | TERMINATED | EARLY_PHASE1
3 Participants

Window Trial to Evaluate Molecular Response to PI3K Inhibition With Copanlisib in r/r Adult B-cell ALL

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2021-06-21
Completion: 2023-04-03
Conditions
Leukemia, Acute Lymphocytic
Interventions
DRUG
No Results Yet
NCT04795323 | COMPLETED | PHASE2
5 Participants

Proof of Concept Study Assessing Technology-Assisted Respiratory Adherence Prototype Version 3 in Individuals With COPD

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2021-04-08
Completion: 2022-03-08
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
DEVICE
NCT04784091 | COMPLETED | PHASE3
412 Participants

Trial to Evaluate the Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2021-04-29
Completion: 2022-05-09
Conditions
Blepharitis
Interventions
DRUG
NCT04777643 | COMPLETED | EARLY_PHASE1
19 Participants

Sex Differences in Neural Response to Cannabidiol

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2022-06-07
Completion: 2023-04-27
Conditions
CBD Neural Responses
Interventions
DRUG OTHER
No Results Yet
NCT04732871 | ACTIVE_NOT_RECRUITING | PHASE3
1720 Participants

Immunogenicity, Safety, Reactogenicity and Persistence of an Investigational Respiratory Syncytial Virus (RSV) Vaccine in Adults Aged 60 Years and Above

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2021-02-15
Completion: 2022-06-06
Conditions
Respiratory Syncytial Virus Infections
Interventions
BIOLOGICAL
NCT04718779 | COMPLETED | PHASE4
4 Participants

A Study of Enzyme Replacement Therapy (VPRIV) in People With Type 1 Gaucher Disease Who Were Previously Treated With Substrate Reduction Therapy

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2021-04-22
Completion: 2023-02-16
Conditions
Gaucher Disease
Interventions
OTHER
NCT04714190 | RECRUITING | PHASE3
351 Participants

A Study of RC48-ADC in Local Advanced or Metastatic Gastric Cancer With the HER2-Overexpression

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2021-03-24
Completion: 2024-12-01
Conditions
Gastric Cancer HER2 Overexpressing Gastric Carcinoma
Interventions
DRUG
No Results Yet
NCT04670549 | COMPLETED | NA
1541 Participants

Improve Osteoarthritis Care

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-11-13
Completion: 2023-02-09
Conditions
Osteoarthritis, Knee Osteoarthritis, Hip
Interventions
OTHER
No Results Yet
NCT04667169 | COMPLETED | NA
76 Participants

Bleeding in Laser Haemorrhoidoplasty

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2015-01-31
Completion: 2018-10-31
Conditions
Hemorrhoids
Interventions
PROCEDURE
No Results Yet
NCT04649957 | COMPLETED
108 Participants

Profiling Recovery of Those Discharged Into the Community With COVID-19

Study Type: OBSERVATIONAL
Last Updated: 2023-12-21
Start Date: 2021-08-01
Completion: 2023-09-06
Conditions
Infections, Respiratory Respiratory Physiology Respiratory Muscle Symptoms and General Pathology
No Results Yet
NCT04645654 | COMPLETED | NA
176 Participants

Brief Postoperative Hypnosis Intervention as Multimodal Analgesia After Major Abdominal Surgery

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-10-01
Completion: 2023-09-30
Conditions
Hypnosis ERAS Postoperative Pain
Interventions
BEHAVIORAL
No Results Yet
NCT04611802 | COMPLETED | PHASE3
33000 Participants

A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults โ‰ฅ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-12-27
Completion: 2023-04-10
Conditions
SARS-CoV Infection Covid19
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT04602195 | COMPLETED
33 Participants

Responsiveness and Validation Study of MFM-32 in SMA Patients Treated With Nusinersen

Study Type: OBSERVATIONAL
Last Updated: 2023-12-21
Start Date: 2021-01-19
Completion: 2023-11-10
Conditions
Spinal Muscular Atrophy
No Results Yet
NCT04588285 | RECRUITING | PHASE2
180 Participants

Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2021-05-04
Completion: 2024-12-01
Conditions
Dementia With Lewy Bodies
Interventions
DRUG
No Results Yet
NCT04583826 | SUSPENDED | NA
40 Participants

sCAVA - Sleep Assessment Using the CAVA Device

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-04-02
Completion: 2025-04-01
Conditions
Sleep
Interventions
DEVICE
No Results Yet
NCT04567160 | COMPLETED | PHASE4
60 Participants

NOL Index to Compare the Intraoperative Analgesic Effect of Propofol Versus Sevoflurane

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-10-01
Completion: 2022-03-17
Conditions
Nociceptive Pain Anesthesia
Interventions
DRUG
No Results Yet
NCT04564911 | ACTIVE_NOT_RECRUITING | NA
206 Participants

GLucose Monitoring Programme SingaporE, Phase 2 (GLiMPSE2)

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-12-22
Completion: 2023-09-30
Conditions
Diabetes Mellitus, Type 2 Flash Glucose Monitoring
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT04532073 | COMPLETED | NA
60 Participants

Sub-study of the Essen Study Centre for the ENTAiER Trial

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2021-07-27
Completion: 2022-12-07
Conditions
Elderly Patients Chronically Ill Increased Risk of Falling
Interventions
OTHER
No Results Yet
NCT04526236 | COMPLETED | PHASE4
60 Participants

Influence of Aging on Perioperative Methadone Dosing

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2019-09-03
Completion: 2022-07-13
Conditions
Pain, Postoperative Opioid Use Methadone Overdose of Undetermined Intent
Interventions
DRUG
No Results Yet
NCT04505397 | COMPLETED | PHASE1
111 Participants

Single-Dose Escalation Study Followed by a Multiple-Dose Escalation Study of SKL24741 in Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-02-13
Completion: 2022-10-27
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT04498377 | TERMINATED | PHASE2
1 Participants

Study of F-652 (IL-22:IgG2 Fusion Protein) in Patients With Moderate to Severe COVID-19

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2021-01-26
Completion: 2021-03-24
Conditions
Covid19
Interventions
BIOLOGICAL
NCT04497389 | COMPLETED | PHASE1/PHASE2
47 Participants

Safety and Feasibility of Amniotic Fluid as a Treatment for COVID-19 Patients

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-10-28
Completion: 2022-08-02
Conditions
SARS CoV-2
Interventions
BIOLOGICAL
NCT04475432 | COMPLETED | PHASE2/PHASE3
421 Participants

Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-09-09
Completion: 2021-05-04
Conditions
Blepharitis
Interventions
DRUG
NCT04425629 | TERMINATED | PHASE3
10078 Participants

Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-06-16
Completion: 2022-01-21
Conditions
COVID-19
Interventions
DRUG
NCT04417218 | COMPLETED | NA
67 Participants

Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-08-17
Completion: 2023-01-01
Conditions
Healthy
Interventions
DIETARY_SUPPLEMENT
NCT04342000 | WITHDRAWN | NA
0 Participants

The Effect of Movement Education on Jumping/Landing Quality in High School Athletes

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2019-10-28
Completion: 2023-08-15
Conditions
ACL Injury
Interventions
OTHER
No Results Yet
NCT04267939 | TERMINATED | PHASE1
14 Participants

ATR Inhibitor Elimusertib (BAY1895344) Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-02-26
Completion: 2023-12-01
Conditions
Advanced Solid Tumors (Excluding Prostate Cancer) Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT04264403 | ACTIVE_NOT_RECRUITING | NA
44 Participants

Renal Denervation in Chronic Kidney Disease - RDN-CKD Study

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-01-23
Completion: 2023-12-23
Conditions
Uncontrolled Hypertension Renal Denervation Chronic Kidney Disease stage3
Interventions
DEVICE
No Results Yet
NCT04237727 | RECRUITING
200 Participants

CAvent-Ventilation During Advanced Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest- a Descriptive Study

Study Type: OBSERVATIONAL
Last Updated: 2023-12-21
Start Date: 2019-03-29
Completion: 2024-12-25
Conditions
Out-of-Hospital Cardiac Arrest Pulmonary Ventilation
Interventions
DEVICE
No Results Yet
NCT04232969 | ACTIVE_NOT_RECRUITING | PHASE3
194 Participants

Exenatide Once Weekly Over 2 Years as a Potential Disease Modifying Treatment for Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-01-20
Completion: 2024-02-24
Conditions
Parkinson's Disease
Interventions
DRUG
No Results Yet
NCT04232267 | COMPLETED
329 Participants

Analysis of Sleep Study Data to Assess Depressive Burden

Study Type: OBSERVATIONAL
Last Updated: 2023-12-21
Start Date: 2020-01-13
Completion: 2022-03-01
Conditions
Sleep Disorder Depressive; Behavioral Disorder Mood Disorders
Interventions
DEVICE
No Results Yet
NCT04228627 | ACTIVE_NOT_RECRUITING | PHASE4
600 Participants

Ferritin Screening And IRon Treatment for Maternal Anemia and FGR Prevention Trial

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2020-08-01
Completion: 2024-01-30
Conditions
Iron Deficiency (Without Anemia) Pregnancy Related
Interventions
DRUG
No Results Yet
NCT04209842 | NOT_YET_RECRUITING | NA
20 Participants

Effectiveness Gastric Balloon in Obese Adolescents

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2024-09-30
Completion: 2026-08-31
Conditions
Obesity, Morbid
Interventions
DEVICE
No Results Yet
NCT04134767 | COMPLETED | NA
234 Participants

Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2019-11-15
Completion: 2022-10-27
Conditions
Substance Use HIV Infections HCV Infection Sexually Transmitted Infections (Not HIV or Hepatitis) Overdose, Drug Opioid Use
Interventions
BEHAVIORAL
NCT04115345 | COMPLETED | PHASE1
6 Participants

A Study of a Renal Autologous Cell Therapy (REACT) in Patients With Chronic Kidney Disease (CKD) From Congenital Anomalies of the Kidney and Urinary Tract (CAKUT).

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2019-08-13
Completion: 2023-01-31
Conditions
Chronic Kidney Disease Congenital Anomalies of Kidney and Urinary Tract
Interventions
BIOLOGICAL
No Results Yet
NCT04096716 | TERMINATED | PHASE1
14 Participants

Mapping Draining Lymph Nodes in CNS Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2019-12-03
Completion: 2022-04-30
Conditions
Central Nervous System Neoplasms Central Nervous System Tumor
Interventions
DRUG
No Results Yet
NCT04093427 | TERMINATED | NA
8 Participants

Influence of an Inverse Pressure Ramp in Long-term Non-invasive Ventilation on Dyspnea in the Morning After Therapy

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2019-08-01
Completion: 2022-07-31
Conditions
Noninvasive Ventilation Dyspnea
Interventions
OTHER
No Results Yet
NCT04088799 | COMPLETED
10 Participants

LDL-Apheresis for FSGS CardioRenal Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2023-12-21
Start Date: 2019-01-01
Completion: 2023-06-01
Conditions
Focal Segmental Glomerulosclerosis
Interventions
OTHER
No Results Yet
NCT04070287 | COMPLETED | EARLY_PHASE1
388 Participants

Innovative Tools to Expand HIV Self-Testing

Study Type: INTERVENTIONAL
Last Updated: 2023-12-21
Start Date: 2019-07-01
Completion: 2020-07-31
Conditions
HIV/AIDS Sexually Transmitted Diseases
Interventions
COMBINATION_PRODUCT
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