Analysis of Sleep Study Data to Assess Depressive Burden

NCT ID: NCT04232267

Last Updated: 2023-12-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

329 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-13

Study Completion Date

2022-03-01

Brief Summary

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This study evaluates the effectiveness of the MEB-001 device in assessing physiological parameters that provide a clinically significant depressive burden screener. This study uses objective physiological markers from MEB-001 to estimate the clinically significant depressive burden as subjectively reported by the subject with the Beck Depression Inventory - II (BDI-II).

Detailed Description

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This study evaluates the effectiveness of the MEB-001 device in assessing physiological parameters that provide a clinically significant depressive burden screener. This study uses objective physiological markers from MEB-001 to estimate the clinically significant depressive burden as subjectively reported by the subject with the BDI-II.

This is a two (2)-phase, non-significant risk, cross-sectional, naturalistic, single-arm, multi-center study conducted under a common protocol and designed to:

Phase 1: MEB-001 algorithm development (software medical device). Phase 2: Evaluate the effectiveness of the MEB-001 device in assessing physiological parameters that provide clinically significant depressive burden screener.

Conditions

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Sleep Disorder Depressive; Behavioral Disorder Mood Disorders

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients prescribed Polysomnology (PSG - sleep study)

Patients that are at least 18 years old but not older than 75 years old, who have been referred to a sleep clinic for sleep disturbance.

MEB-001

Intervention Type DEVICE

Software medical device used to aid in the screening of patients with potential depressive burden symptoms.

Interventions

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MEB-001

Software medical device used to aid in the screening of patients with potential depressive burden symptoms.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subject is age ≥18 years and ≤75 years.
* Subject is willing and able to provide consent.
* Subject has the ability to read and understand the instructions for the study.
* Subject is willing to adhere to study procedures.
* Subject is willing to undergo full night PSG study, as prescribed.

Exclusion Criteria

* Subject has a pacemaker.
* Subject is suspected or known to have active alcohol or drug abuse (including but not limited to abuse of marijuana).
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medibio Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Melissa Bruner

Role: STUDY_DIRECTOR

Medibio Limited

Archie Defillo, MD

Role: STUDY_CHAIR

Medibio Limited

Archie Defillo, MD

Role: PRINCIPAL_INVESTIGATOR

Medibio Limited

Locations

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Restore Sleep Clinic

Blaine, Minnesota, United States

Site Status

Lakeland Sleep and CPAP

Plymouth, Minnesota, United States

Site Status

Ohio Sleep Solutions

Columbus, Ohio, United States

Site Status

Ohio Sleep Solutions

Grove City, Ohio, United States

Site Status

Ohio Sleep Solutions

Hilliard, Ohio, United States

Site Status

Countries

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United States

Other Identifiers

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CIP-0018

Identifier Type: -

Identifier Source: org_study_id