Clinical Trials
Showing trials with last updates posted in 2020.
30
Participants
Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2015-03-25
Completion:
2017-01-09
Conditions
Normal Hepatic Function
Impaired Hepatic Function
Interventions
DRUG
No Results Yet
47
Participants
PCA062 in pCAD-positive Tumors.
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2015-04-15
Completion:
2018-07-17
Conditions
Triple Negative Breast Cancer
Head & Neck Cancer
Esophageal Cancer
Interventions
DRUG
No Results Yet
33
Participants
A Phase 1 Study of Osilodrostat (LCI699) in Healthy Volunteers and Subjects With Impaired Hepatic Function
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2015-04-21
Completion:
2016-05-19
Conditions
Hepatic Impairment
Interventions
DRUG
No Results Yet
162
Participants
A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2015-04-20
Completion:
2018-11-08
Conditions
Breast Cancer
Non-small Cell Lung Cancer
Melanoma
Brain Metastases
Interventions
DRUG
240
Participants
Prospective Clinical 5-year Follow-up of the LINK® SP-CL® Hip Prosthesis Stem
Study Type:
OBSERVATIONAL
Last Updated:
2020-12-19
Start Date:
2015-07-31
Completion:
2022-05-31
Conditions
Osteoarthritis, Hip
Femur Head Necrosis
Femoral Neck Fractures
No Results Yet
105
Participants
Trial of Diet in Gestational Diabetes Mellitus: Metabolic Consequences to Mother and Offspring
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2015-07-31
Completion:
2019-11-30
Conditions
Gestational Diabetes Mellitus
Interventions
BEHAVIORAL
No Results Yet
7
Participants
A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2014-07-31
Completion:
2019-05-31
Conditions
Breast Feeding
Constipation
Irritable Bowel Syndrome
Interventions
DRUG
No Results Yet
13
Participants
Dose Escalation Study of LEE011 in Combination With Buparlisib and Letrozole in HR+, HER2-negative Post-menopausal Women With Advanced Breast Cancer.
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2014-06-27
Completion:
2016-10-26
Conditions
Advanced or Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
37
Participants
Everolimus, Letrozole and Trastuzumab in HR- and HER2/Neu-positive Patients
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2014-07-17
Completion:
2020-12-14
Conditions
Advanced Malignant Solid Neoplasm
Estrogen Receptor Positive
HER2/Neu Positive
Postmenopausal
Premenopausal
Progesterone Receptor Positive
Recurrent Breast Carcinoma
Refractory Breast Carcinoma
Refractory Hormone Receptor Positive Breast Carcinoma
Stage IIIA Breast Cancer AJCC v7
Stage IIIB Breast Cancer AJCC v7
Stage IIIC Breast Cancer AJCC v7
Stage IV Breast Cancer AJCC v6 and v7
Interventions
DRUG
OTHER
BIOLOGICAL
No Results Yet
1517
Participants
Boostrix® Pregnancy Registry
Study Type:
OBSERVATIONAL
Last Updated:
2020-12-19
Start Date:
2014-03-31
Completion:
2019-08-02
Conditions
Pertussis
Interventions
OTHER
19
Participants
Pharmacokinetics of rFVIIIFc at Two Vial Strengths
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2014-03-31
Completion:
2014-10-31
Conditions
Severe Hemophilia A
Interventions
BIOLOGICAL
97
Participants
A Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2014-03-07
Completion:
2017-12-05
Conditions
Advanced Cancer
Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Hepatocellular Cancer
Renal Cell Carcinoma
Non-Small Cell Lung Cancer
Interventions
DRUG
51
Participants
A Phase 1 Study of an Investigational Drug, ALN-AT3SC, in Healthy Volunteers and Hemophilia A or B Patients
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2014-01-20
Completion:
2017-07-20
Conditions
Hemophilia A
Hemophilia B
Interventions
DRUG
No Results Yet
9
Participants
Safety and Tolerability of Oral LCL161 in Japanese Adult Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2013-11-30
Completion:
2015-06-30
Conditions
Neoplasms
Interventions
DRUG
No Results Yet
36
Participants
Effect of Hepatic Impairment on LDK378 Pharmacokinetics
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2014-01-31
Completion:
2016-09-30
Conditions
Normal Hepatic Function
Impaired Hepatic Function
Interventions
DRUG
No Results Yet
17
Participants
A Phase I Study of LEE011 in Asian Patients
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2013-05-31
Completion:
2015-01-31
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
31
Participants
Safety and Efficacy of AEB071 and EVEROLIMUS in Patients With CD79-mutant or ABC Subtype Diffuse Large B-Cell Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2013-12-05
Completion:
2016-06-01
Conditions
CD79 Mutant or ABC-subtype Diffuse Large B-Cell Lymphoma
Interventions
DRUG
No Results Yet
15
Participants
BCI and FES for Hand Therapy in Spinal Cord Injury
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2013-05-08
Completion:
2018-12-31
Conditions
Spinal Cord Injury
Interventions
DEVICE
No Results Yet
48
Participants
Study of Safety & Efficacy of the Combination of LJM716 & BYL719 in Patients With Previously Treated Esophageal Squamous Cell Carcinoma (ESCC)
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2013-07-26
Completion:
2016-06-03
Conditions
Esophageal Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
22
Participants
Phase Ib Study of LDK378 and AUY922 in ALK-rearranged Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2013-06-30
Completion:
2016-01-31
Conditions
Anaplastic Lymphoma Kinase (ALK)
Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
114
Participants
Phase I Study to Evaluate the Effect of LDE225 on the Pharmacokinetics of Bupropion and Warfarin in Patients
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2013-04-30
Completion:
2016-08-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
33
Participants
Effect of Hepatic Impairment on LDE225..
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2013-03-31
Completion:
2015-03-31
Conditions
Normal Hepatic Function
Impaired Hepatic Function
Interventions
DRUG
No Results Yet
63
Participants
A Study to Find the Maximum Tolerated Dose of the Experimental Combination of the Drugs INC424 and BKM120 in Patients With Primary or Secondary Myelofibrosis
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-12-18
Completion:
2017-09-28
Conditions
Myelofibrosis
Interventions
DRUG
No Results Yet
22
Participants
Study of Safety and Preliminary Efficacy for LDK378 in Japanese Patients With Genetic Alterations in Anaplastic Lymphoma Kinase (ALK)
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-06-30
Completion:
2016-01-31
Conditions
Tumors Characterized by Genetic Alterations in Anaplastic Lymphoma Kinase (ALK)
Interventions
DRUG
No Results Yet
1
Participants
Safety and Tolerability of Intravenous LFG316 in Wet Age-related Macular Degeneration (AMD).
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-12-31
Completion:
2013-05-31
Conditions
Neovascular Age-related Macular Degeneration
Interventions
DRUG
No Results Yet
10
Participants
A Phase Ib Study of Panobinostat (LBH589) in Combination With 5-Azacitidine for Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML) or Acute Myeloid Leukemia (AML) Patients
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-08-31
Completion:
2014-05-31
Conditions
Myelodysplastic Syndromes (MDS)
Chronic Myelomonocytic Leukemia (CMML)
Acute Myeloid Leukemia (AML)
Interventions
DRUG
No Results Yet
48
Participants
Comparing the Pharmacokinetics, Safety and Tolerability of NVA237 in Renal Impairment
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2010-06-30
Completion:
2010-11-30
Conditions
Renal Impairment
Interventions
DRUG
No Results Yet
64
Participants
Phase I Study LJM716 Combined With Trastuzumab in Patients With HER2 Overexpressing Metastatic Breast or Gastric Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-09-21
Completion:
2017-08-02
Conditions
Advanced HER2-positive Breast Cancer or Gastric Cancer
Interventions
DRUG
No Results Yet
9
Participants
Safety and Efficacy of SAF312 in Patients With Neurogenic Detrusor Overactivity Due to Spinal Cord Lesions
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-01-31
Completion:
2012-09-30
Conditions
Neurogenic Urinary Bladder
Neurogenic Bladder Disorder
Neurogenic Dysfunction of the Urinary Bladder
Neurogenic Bladder, Uninhibited
Neurogenic Bladder, Spastic
Interventions
DRUG
No Results Yet
54
Participants
A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-07-31
Completion:
2014-03-31
Conditions
HER2 + Breast Cancer, HER2 + Gastric Cancer, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma
HER2 + Breast Cancer
HER2 + Gastric Cancer
Squamous Cell Carcinoma of Head and Neck
Esophageal Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
53
Participants
Pharmacokinetics of LCQ908 in Patients With Hepatic Impairment
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-04-30
Completion:
2013-04-30
Conditions
Hepatic Impairment
Interventions
DRUG
No Results Yet
120
Participants
Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-07-31
Completion:
2015-04-30
Conditions
Dose Escalation
Safety
Preliminary Efficacy
Advanced Solid Tumors
Metastatic Breast Cancer
Advanced Pancreatic Adenocarcinoma
Metastatic Colorectal Cancer
Recurrent Glioblastoma Multiforme
Gastric Cancer
Gastroesophageal Junction Cancer
Triple Negative Metastatic Breast Cancer
Hormone Receptor Positive (ER+/PR+, and Her2-) Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
88
Participants
A Clinical Trial of a Metal on Poly Component Versus CORAIL Stem: A Bone Mineral Density Study
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2010-04-30
Completion:
2019-07-31
Conditions
Total Hip Arthroplasty
Interventions
DEVICE
58
Participants
Pharmacokinetics of LCQ908 in Patients With Renal Impairment
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-05-31
Completion:
2013-03-31
Conditions
Renal Impairment
Interventions
DRUG
No Results Yet
118
Participants
Renal Hemodynamic Effects of RLX030A in Subjects With Chronic Heart Failure (CHF)
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-02-29
Completion:
2012-12-31
Conditions
Chronic Heart Failure (CHF)
Interventions
DRUG
No Results Yet
44
Participants
A Phase I Study of INC280 in Japanese Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-02-29
Completion:
2016-01-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
43
Participants
Safety and Efficacy of Intravitreal LFG316 in Wet Age Related Macular Degeneration (AMD)
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-02-29
Completion:
2013-07-31
Conditions
Neovascular Age-elated Macular Degeneration (Wet AMD)
Exudative Macular Degeneration
Interventions
DRUG
No Results Yet
18
Participants
Dose-escalation, and Safety Study of LDE225 and Gemcitabine in Locally Advanced or Metastatic Pancreatic Cancer Patients
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-03-31
Completion:
2014-07-31
Conditions
Pancreatic Cancer
Interventions
DRUG
No Results Yet
71
Participants
Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Recombinant Coagulation Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Pediatric Subjects With Hemophilia A
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2012-11-30
Completion:
2013-12-31
Conditions
Hemophilia A
Interventions
DRUG
240
Participants
Long-Term Safety and Efficacy of rFVIIIFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia A
Study Type:
INTERVENTIONAL
Last Updated:
2020-12-19
Start Date:
2011-12-31
Completion:
2017-10-31
Conditions
Hemophilia A
Interventions
DRUG
Showing 40 trials per page · Total 34893 trials