WELL-MPN: A Digital Lifestyle App for Patients With MPNs

NCT ID: NCT07349134

Last Updated: 2026-01-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-06-30

Study Completion Date

2029-06-30

Brief Summary

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The goal of this clinical trial is to learn whether a digital lifestyle app can help improve diet, physical activity, symptoms, emotional well-being, and quality of life in adults with myeloproliferative neoplasms (MPNs).

The main questions it aims to answer are:

Can people with MPNs use the WELL-MPN app?

Does using the WELL-MPN app improve diet quality and physical activity?

Does the WELL-MPN app improve MPN-related symptoms, anxiety and depression, confidence in managing health, and overall quality of life?

Researchers will compare participants who use the WELL-MPN digital app with participants who receive written educational materials about diet and physical activity for people with cancer to see if the app leads to greater improvements in lifestyle behaviors, symptoms, and well-being.

Participants will:

Be randomly assigned to use the WELL-MPN app or receive written lifestyle education materials

Use the assigned program or materials over the study period

Complete surveys about diet, physical activity, symptoms, mood, confidence in self-care, and quality of life

Detailed Description

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Conditions

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Myeloproliferative Neoplasms (MPNs)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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WELL-MPN Digital App

WELL-MPN app and usual care

Group Type EXPERIMENTAL

WELL-MPN Digital App

Intervention Type BEHAVIORAL

Patients randomized to the WELL-MPN arm will be given access to the WELL-MPN digital program (app) which provides lifestyle counseling through an iPad.

Enhanced Usual Care

Usual care and written literature about diet and physical activity guidelines in patients with cancer

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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WELL-MPN Digital App

Patients randomized to the WELL-MPN arm will be given access to the WELL-MPN digital program (app) which provides lifestyle counseling through an iPad.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with a myeloproliferative neoplasm (MPN) by World Health Organization 2016 criteria
* Adult (age \>/= 18)
* Able to comprehend and speak English
* Able to provide informed consent

Exclusion Criteria

* Unable to comprehend and speak English
* Unable to provide informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Brigham and Women's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Chi-Joan How, MD

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Chi-Joan How

Role: PRINCIPAL_INVESTIGATOR

Massachusetts General Hospital

Locations

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Mass General Brigham

Boston, Massachusetts, United States

Site Status

Countries

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United States

Central Contacts

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Chi-Joan How

Role: CONTACT

617-732-5190

Facility Contacts

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Chi-Joan How

Role: primary

6177325190

Other Identifiers

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25-805

Identifier Type: -

Identifier Source: org_study_id

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