Factors Associated With Mortality in Streptococcal Anginosus Bacteremia

NCT ID: NCT07343167

Last Updated: 2026-01-15

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 400 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-09-08
• Study Completion Date: 2027-03-08

Brief Summary

Streptococcal anginosus infections (S. constellatus, S. anginosus, and S. intermedius) are characterized by their severity, linked to high mortality and frequent infectious complications. Several studies in the literature highlight this severity, with mortality rates estimated at around 15%.

The aim of this research is to identify the factors associated with mortality in Streptococcal anginosus bacteremia.

Conditions

Streptococcal Infections

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: RETROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Major subject (≥18 years old)
• Hospitalized between January 1, 2019, and December 31, 2024, in one of the participating centers
• Having presented during the study period at least one positive blood culture for Streptococcus anginosus, Streptococcus constellatus, or Streptococcus intermedius in a laboratory at a participating center

Exclusion Criteria

• Refusal to participate in the study

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Strasbourg, France

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Centre de référence des maladies vectorielles à tiques, CNR Borrelia - CHU de Strasbourg - France

Strasbourg, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Victor GERBER, MD

Role: CONTACT

victor.gerber@chru-strasbourg.fr

33 3 68 85 37 97

Facility Contacts

Victor Gerber, MD

Role: primary

victor.gerber@chru-strasbourg.frr

33 3 68 85 37 97

Other Identifiers

9821

Identifier Type: -

Identifier Source: org_study_id