A Study to Evaluate Clinical Benefit, Performance and Safety of Cochlear Implants in Adults

NCT ID: NCT07338864

Last Updated: 2026-01-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

66 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-04-30

Study Completion Date

2028-09-30

Brief Summary

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The aim of this clinical investigation is to demonstrate the performance, clinical benefit and safety of commercial cochlear implant systems. Speech performance and subjective hearing results, and comparison with cochlear implant results available in literature, is intended to demonstrate the performance and clinical benefit of the cochlear implant systems investigated in this study.

Detailed Description

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Conditions

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Hearing Loss Hearing Implants

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cochlear implant (CI1032)

Participants implanted with a CI1032

Cochlear Nucleus Nexa Cochlear implant (CI1032)

Intervention Type DEVICE

Participants will be implanted with a CI1032 cochlear implant as determined by the treating clinician

Cochlear implant (CI1022)

Participants implanted with a CI1022

Cochlear Nucleus Nexa Cochlear implant (CI1022)

Intervention Type DEVICE

Participants will be implanted with a CI1022 cochlear implant as determined by the treating clinician

Cochlear implant (CI1012)

Participants implanted with a CI1012

Cochlear Nucleus Nexa Cochlear implant (CI1012)

Intervention Type DEVICE

Participants will be implanted with a CI1012 cochlear implant as determined by the treating clinician

Interventions

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Cochlear Nucleus Nexa Cochlear implant (CI1032)

Participants will be implanted with a CI1032 cochlear implant as determined by the treating clinician

Intervention Type DEVICE

Cochlear Nucleus Nexa Cochlear implant (CI1022)

Participants will be implanted with a CI1022 cochlear implant as determined by the treating clinician

Intervention Type DEVICE

Cochlear Nucleus Nexa Cochlear implant (CI1012)

Participants will be implanted with a CI1012 cochlear implant as determined by the treating clinician

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Aged 18 years or older (at time of consent).
* Clinically established post-linguistic moderately severe to profound sensorineural hearing loss, in the ear to be implanted.
* Compromised functional hearing with hearing aid(s) or unlikely to receive benefit with hearing aid(s) in the ear to be implanted.
* Cochlear implant candidate as determined by the Principal Investigator. Meets local candidacy criteria for cochlear implantation.
* Candidate is a fluent speaker in the language used to assess speech perception performance.
* Willing and able to comply with study follow-up schedule.
* Willing and able to provide written informed consent.
* Candidate has access to a Smartphone compatible with Nucleus Smart App.

Exclusion Criteria

* Prior cochlear implantation in the ear to be implanted.
* Unrealistic expectations regarding the possible benefit, risks and limitations that are inherent to the surgical procedure and prosthetic device as determined by the investigator.
* Any contraindications for cochlear implantation listed in the relevant product physician's guide (to be specified per sub-investigation).
* Unable or unwilling to comply with the requirements of the clinical investigation as determined by the Investigator.
* Investigator site personnel directly affiliated with this study and/or their immediate families; immediate family is defined as spouse, parent, child or sibling.
* Cochlear employees or employees of Contract Research Organisations or contractors engaged by Cochlear for the purposes of this investigation.
* Women who are pregnant.
* Current participation, or participation in an interventional clinical study/trial in the past 30 days, involving an investigational drug or device (unless Cochlear sponsored and determined by Investigator or Sponsor to not impact this investigation).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cochlear

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Universitätsklinikum Düsseldorf

Düsseldorf, , Germany

Site Status

Countries

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Germany

Central Contacts

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[email protected] PRS Specialist

Role: CONTACT

61 2 9428 6555

Other Identifiers

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CLTD5819

Identifier Type: -

Identifier Source: org_study_id

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