Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array

NCT ID: NCT06936449

Last Updated: 2025-12-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

19 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-05

Study Completion Date

2028-03-31

Brief Summary

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A long-term follow-up of Cochlear's cochlear implant electrode array which passively elutes dexamethasone for a defined period of time to help reduce inflammatory responses.

Detailed Description

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Conditions

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Sensorineural Hearing Loss Bilateral Hearing Loss

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Experimental: CI632D Investigational Medical Device (IMD)

Adults with bilateral postlinguistic sensorineural hearing loss, who have received the CI632D cochlear implant

CI632D

Intervention Type DEVICE

CI632 cochlear implant with Slim Modiolar electrode including dexamethasone in the electrode within wells

Active Comparator: CI632 Comparator Device

Adults with bilateral postlinguistic sensorineural hearing loss, who have received the CI632 cochlear implant

CI632

Intervention Type DEVICE

CI632 cochlear implant with Slim Modiolar electrode with market approval and does not include dexamethasone

Interventions

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CI632D

CI632 cochlear implant with Slim Modiolar electrode including dexamethasone in the electrode within wells

Intervention Type DEVICE

CI632

CI632 cochlear implant with Slim Modiolar electrode with market approval and does not include dexamethasone

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subjects who completed study obligations of the CLTD5759 CI-DEX study and enrolled at a site selected for participation.
* Subjects implanted with a CI632D or a CI632 cochlear implant under the CLTD5759 (NCT04750642).
* Willing and able to provide written informed consent.

Exclusion Criteria

* Unrealistic expectations on the part of the subject, regarding the possible benefits, risks, and limitations that are inherent to participation as determined by the Investigator.
* Additional disabilities that may affect the subject's participation or safety during the clinical investigation.
* Unable or unwilling to comply with all the requirements of the clinical investigation as determined by the Investigator.
* Currently participating, or participated within the last 30 days, in another interventional clinical investigation/trial involving an investigational drug or device.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cochlear

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Rocky Mountain Ear Center

Englewood, Colorado, United States

Site Status RECRUITING

University of Iowa

Iowa City, Iowa, United States

Site Status RECRUITING

University Hospitals Cleveland

Cleveland, Ohio, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Aaron Parkinson

Role: CONTACT

800 523 5798

Facility Contacts

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Aaron Parkinson

Role: primary

800 523 5798

Aaron Parkinson

Role: primary

800 523 5798

Aaron Parkinson

Role: primary

800 523 5798

Other Identifiers

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CLTD5759-S1

Identifier Type: -

Identifier Source: org_study_id

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