Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

NCT ID: NCT07335211

Last Updated: 2026-01-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE3

Total Enrollment

206 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-01-31

Study Completion Date

2027-12-31

Brief Summary

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A multicenter, randomized, single-blind, active controlled, phase III clinical trial to evaluate the efficacy and safety of HUC3-637 in patients with primary open angle glaucoma or ocular hypertension

Detailed Description

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Conditions

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Primary Open Angle Glaucoma (POAG) Ocular Hypertension

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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HUC3-637

Dorzolamide, Timolol

Group Type EXPERIMENTAL

HUC3-637

Intervention Type DRUG

Ophthalmic solution instilled directly into the eye (topical ocular administration)

HUC3-637-R

Dorzolamide, Timolol

Group Type ACTIVE_COMPARATOR

HUC3-637-R

Intervention Type DRUG

Ophthalmic solution instilled directly into the eye (topical ocular administration)

Interventions

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HUC3-637

Ophthalmic solution instilled directly into the eye (topical ocular administration)

Intervention Type DRUG

HUC3-637-R

Ophthalmic solution instilled directly into the eye (topical ocular administration)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Adults aged 19 years and older
* Participants diagnosed with POAG or OH
* Have fully explained and understood the study and have voluntarily given written informed consent.

Exclusion Criteria

* Acute or chronic angle-closure glaucoma
* Congenital glaucoma, secondary glaucoma (open-angle glaucoma)
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Huons Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Kangbuk Samsung Hospital

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Rang Lee

Role: CONTACT

07074926091

Other Identifiers

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HUC3-637

Identifier Type: -

Identifier Source: org_study_id

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