Prevalence of Cerebral Large Vessel Occlusion Among Acute Ischemic Stroke Patients in Assiut University Hospitals
NCT ID: NCT07326410
Last Updated: 2026-01-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
300 participants
OBSERVATIONAL
2026-02-01
2027-03-01
Brief Summary
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1. Study Objectives
Primary Objective:
\- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals
Secondary Objectives:
* To describe clinical and radiological characteristics of LVO patients.
* To assess factors associated with LVO (age, sex, stroke severity, comorbidities).
2. Study Design
* Type: single center, prospective observational cross-sectional study
* Duration: 12-month recruitment period
* Setting: Assiut university hospitals, stroke unit.
3. Study Population
Inclusion Criteria:
* Adults (≥18 years)
* Diagnosed with acute ischemic stroke within 24 hours of symptom onset
* Underwent vascular imaging (CTA or MRA) on admission
Exclusion Criteria:
* Hemorrhagic stroke
* Stroke mimics
* Incomplete imaging data 4. Definitions
Large Vessel Occlusion (LVO) defined as occlusion in:
* Intracranial ICA
* M1 or proximal M2 segments of MCA
* Basilar artery ± Optional: A1 6. Data Collection
Clinical Data:
* Demographics (age, sex)
* Risk factors (HTN, DM, AF, CAD, smoking)
* NIHSS on admission and discharge mRS on admission and discharge
* Onset-to-door time
* Imaging modality used
Imaging Data:
* Site of occlusion
* ASPECTS (optional)
* Collateral status (optional if available)
Hospital Data:
* Facility type (public vs private)
* Door-to-CT and door-to-CTA times 8. Analysis Plan
* Primary: Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging
* Subgroup analysis: By age group, sex, region, NIHSS
* Secondary: Logistic regression to identify predictors of LVO
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Detailed Description
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1. Study Objectives
Primary Objective:
\- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals
Secondary Objectives:
* To describe clinical and radiological characteristics of LVO patients.
* To assess factors associated with LVO (age, sex, stroke severity, comorbidities).
2. Study Design
* Type: single center, prospective observational cross-sectional study
* Duration: 12-month recruitment period
* Setting: Assiut university hospitals, stroke unit.
3. Study Population
Inclusion Criteria:
* Adults (≥18 years)
* Diagnosed with acute ischemic stroke within 24 hours of symptom onset
* Underwent vascular imaging (CTA or MRA) on admission
Exclusion Criteria:
* Hemorrhagic stroke
* Stroke mimics
* Incomplete imaging data 4. Definitions
Large Vessel Occlusion (LVO) defined as occlusion in:
* Intracranial ICA
* M1 or proximal M2 segments of MCA
* Basilar artery ± Optional: A1 6. Data Collection
Clinical Data:
* Demographics (age, sex)
* Risk factors (HTN, DM, AF, CAD, smoking)
* NIHSS on admission and discharge mRS on admission and discharge
* Onset-to-door time
* Imaging modality used
Imaging Data:
* Site of occlusion
* ASPECTS (optional)
* Collateral status (optional if available)
Hospital Data:
* Facility type (public vs private)
* Door-to-CT and door-to-CTA times 8. Analysis Plan
* Primary: Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging
* Subgroup analysis: By age group, sex, region, NIHSS
* Secondary: Logistic regression to identify predictors of LVO
Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Eligibility Criteria
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Inclusion Criteria
* Diagnosed with acute ischemic stroke within 24 hours of symptom onset
* Underwent vascular imaging (CTA or MRA) on admission
Exclusion Criteria
* Stroke mimics
* Incomplete imaging data
18 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Ahmad Tarek Aly Sayed
Resident of neurology
Central Contacts
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Related Links
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Prevalence of cerebral Large Vessel Occlusion among acute ischemic stroke
Other Identifiers
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Prevalence of Cerebral LVO
Identifier Type: -
Identifier Source: org_study_id
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