Safety and Effectiveness of Sculptra 011611 for Improvement in Appearance of Gluteal Skin Irregularities

NCT ID: NCT07324564

Last Updated: 2026-01-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

125 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-11-24

Study Completion Date

2027-04-30

Brief Summary

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The main purpose of the study is to investigate the safety and effectiveness of Sculptra 011611 for improvement in appearance of gluteal skin irregularities.

Detailed Description

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Conditions

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Gluteal Skin Irregularities

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
Evaluator blinded

Study Groups

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Treatment Group

Participants will receive three subcutaneous injection of single regimen of Sculptra 011611. A single regimen consists of up to three injection sessions spaced 1 month (+2 weeks) apart at Baseline, Month 1 and Month 2.

Group Type EXPERIMENTAL

Sculptra 016011

Intervention Type DEVICE

Freeze-dried powder for injection.

Control Group

Participants will be randomized to not receive any intervention.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Sculptra 016011

Freeze-dried powder for injection.

Intervention Type DEVICE

Other Intervention Names

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Poly L Lactic Acid (PLLA)

Eligibility Criteria

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Inclusion Criteria

* Participant with moderate to severe skin laxity in the buttocks when standing with the buttocks in repose as evaluated using the Buttocks' Skin Laxity Visual Scale (SLVS) by the Blinded Evaluator and Treating Investigator at the Baseline visit.
* Women 18 years of age and older.
* Has intent to undergo treatment to improve skin quality and skin irregularities in the buttock area.

Exclusion Criteria

* Previous surgery in or near the treatment area.
* Previous treatment/procedure in or near the treatment area OR is planning to undergo any procedures affecting the treatment area, at any time during the study.
* Presence of any disease or lesions near or on the area to be treated.
* Evidence of scar-related disease or delayed healing activity within 1 year prior to the Baseline visit, or participants susceptible to keloid formation, hyperpigmentation or hypertrophic scarring from injectable procedures.
* Skin coloring/bleaching/tattoo/stretch marks in the treatment area, which, in the Treating Investigator's opinion, would interfere with the study injections and/or study assessment.
* An underlying known disease, a surgical or medical condition that would expose the participant to undue risk.
* Treatment with chemotherapy, immunosuppressive agents, topical and systemic prescription retinoids, topical and systemic corticosteroids within 3 months before treatment.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Galderma R&D

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Site 8688

Vancouver, British Columbia, Canada

Site Status RECRUITING

Site 7049

Vancouver, British Columbia, Canada

Site Status RECRUITING

Site 8379

Burlington, Ontario, Canada

Site Status RECRUITING

Site 8689

Toronto, Ontario, Canada

Site Status RECRUITING

Site 8162

Woodbridge, Ontario, Canada

Site Status RECRUITING

Site 8690

Westmount, Quebec, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Clinical Project Manager

Role: CONTACT

817-961-5000

Other Identifiers

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43CASA2406

Identifier Type: -

Identifier Source: org_study_id

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