The Optimal Measurement Time for the New Gallbladder Function Assessment Method
NCT ID: NCT07321431
Last Updated: 2026-01-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
120 participants
INTERVENTIONAL
2026-01-07
2026-12-20
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
DIAGNOSTIC
DOUBLE
Study Groups
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fried eggs
First, the intervention of oral administration of 2 fried eggs is carried out. The size of the gallbladder is evaluated by ultrasound examination. The washout period is 1 week. After that, the first intervention process of group B is repeated.
oral administration of 2 fried eggs
First, the intervention of oral administration of 2 fried eggs is carried out. The size of the gallbladder is evaluated by ultrasound examination. The washout period is 1 week. After that, the first intervention process of group B is repeated.
protein bars
First, an intervention with oral protein bars + 50ml olive oil is conducted. The size of the gallbladder is evaluated through ultrasound examination. The washout period is 1 week. After that, the first intervention process of Group A is repeated.
oral protein bars + 50ml olive oil
First, an intervention with oral protein bars + 50ml olive oil is conducted. The size of the gallbladder is evaluated through ultrasound examination. The washout period is 1 week. After that, the first intervention process of Group A is repeated.
Interventions
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oral administration of 2 fried eggs
First, the intervention of oral administration of 2 fried eggs is carried out. The size of the gallbladder is evaluated by ultrasound examination. The washout period is 1 week. After that, the first intervention process of group B is repeated.
oral protein bars + 50ml olive oil
First, an intervention with oral protein bars + 50ml olive oil is conducted. The size of the gallbladder is evaluated through ultrasound examination. The washout period is 1 week. After that, the first intervention process of Group A is repeated.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Previous gallstone removal surgery with gallbladder preservation
* Other biliary tract diseases and related surgical history
* History of acute or chronic pancreatitis
* History of gastrointestinal surgery
* Gastrointestinal obstruction
* Dysfunction of the sphincter of Oddi
* Gallbladder neck polyps
* Abnormal gallbladder structure
* Gallbladder mass
* Biliary infection or stones
* Congenital biliary abnormalities
* Biliary injury or surgery
* Biliary tumors
* Gastrointestinal bleeding, liver cirrhosis, or other malignant diseases
* Significant arrhythmia, bradycardia, or atrioventricular block
* Severe hypertension, liver or kidney insufficiency
* Immune, endocrine, hematological, or mental disorders
* Severe cerebrovascular disease
* Allergy to relevant foods
* Pregnant or breastfeeding women
* Unwillingness or inability to consent to participation
18 Years
70 Years
ALL
Yes
Sponsors
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Hepatopancreatobiliary Surgery Institute of Gansu Province
OTHER
Responsible Party
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Wenbo Meng
Director of Surgery
Principal Investigators
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Wenbo Meng, M.D. Ph. D.
Role: PRINCIPAL_INVESTIGATOR
Hepatopancreatobiliary Surgery Institute of Gansu Province
Locations
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Hepatopancreatobiliary Surgery Institute of Gansu Province
Lanzhou, Gansu, China
The First Hospital of Qinhuangdao
Qinhuangdao, Hebei, China
The Jinqiu Hospital of Liaoning Province
Shenyang, Liaoning, China
People's Hospital of Ningxia Hui Autonomous Region
Yinchuan, Ningxia, China
Honghui Hospital of Xi'an Jiaotong University
Xi’an, Shanxi, China
Countries
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Central Contacts
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Facility Contacts
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References
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Ai XN, Wang TF, Zhang Q, Ouyang CG, Wu ZY. Changes in Gallbladder Contractile Function and its Influencing Factors After Minimally Invasive Gallbladder-Preserving Surgery for Cholecystitis With Incarcerated Gallstones. Front Surg. 2022 Jul 14;9:926141. doi: 10.3389/fsurg.2022.926141. eCollection 2022.
Rehfeld JF. Clinical endocrinology and metabolism. Cholecystokinin. Best Pract Res Clin Endocrinol Metab. 2004 Dec;18(4):569-86. doi: 10.1016/j.beem.2004.07.002.
Other Identifiers
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GB evaluating
Identifier Type: -
Identifier Source: org_study_id
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