Real-world Secukinumab Outcomes in Canadian HS Patients

NCT ID: NCT07282015

Last Updated: 2026-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

142 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-12-12

Study Completion Date

2028-01-15

Brief Summary

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The HS-RISE study aims to assess real-world HS treatment outcomes and patterns, safety of secukinumab, and to describe the baseline characteristics of patients diagnosed with moderate-to- severe HS who are prescribed secukinumab in Canadian routine clinical practice.

Detailed Description

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Conditions

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Hidradenitis Suppurativa

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Secukinumab

Patients with moderate-to-severe HS who are prescribed secukinumab in Canadian routine clinical practice

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Patients must give written, signed, and dated informed consent before any information is collected and any study-related activity is performed.
2. Adult patients at the time of informed consent signature.
3. Patients with the diagnosis of moderate-to-severe HS, as determined by the dermatologist.
4. Patients who have been newly prescribed secukinumab as part of routine clinical care according to the approved Canadian PM. The decision to prescribe secukinumab must be made prior to,and independent of, study participation. First treatment with secukinumab must occur no more than 7 days (≤7 days) prior to Baseline visit.
5. Patients who can understand written and spoken Canadian English or French.

Exclusion Criteria

1. Any medical or psychological condition in the treating physician's opinion that may prevent the patient from study participation.
2. Patients who have any contraindications to treatment with secukinumab, as defined in the Canadian PM.
3. Patients who have had any prior exposure to secukinumab (i.e., \>7 days prior to the baseline visit).
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Novartis Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Novartis Pharmaceuticals

Role: STUDY_DIRECTOR

Novartis Pharmaceuticals

Locations

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Novartis Investigative Site

Winnipeg, Manitoba, Canada

Site Status RECRUITING

Novartis Investigative Site

Hamilton, Ontario, Canada

Site Status RECRUITING

Novartis Investigative Site

Markham, Ontario, Canada

Site Status RECRUITING

Novartis Investigative Site

Mississauga, Ontario, Canada

Site Status RECRUITING

Novartis Investigative Site

Richmond Hill, Ontario, Canada

Site Status RECRUITING

Novartis Investigative Site

Waterloo, Ontario, Canada

Site Status RECRUITING

Novartis Investigative Site

Sherbrooke, Quebec, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Novartis Pharmaceuticals

Role: CONTACT

+41613241111

Novartis Pharmaceuticals

Role: CONTACT

Other Identifiers

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CAIN457MCA01

Identifier Type: -

Identifier Source: org_study_id

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