STUMBL vs TTSS in Predicting Morbidity and Mortality of Blunt Chest Trauma

NCT ID: NCT07270354

Last Updated: 2025-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

124 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-12-30

Study Completion Date

2026-12-30

Brief Summary

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This study aim to compare the effectiveness of the STUMBL Score and the Thoracic Trauma Severity Score (TTSS) in predicting morbidity and mortality in patients with blunt chest wall trauma, and to evaluate which scoring system provides greater clinical utility for early risk stratification and management decisions.

Detailed Description

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Blunt chest wall trauma poses a clinical challenge due to its substantial contribution to morbidity and mortality, particularly following falls and vehicular accidents. Early identification of patients at high risk of complications is critical yet difficult, as delayed respiratory issues often escape initial detection. Traditional trauma scoring systems (e.g. ISS, AIS) lack specificity for isolated thoracic injury, creating a niche for more focused prognostic tools.

Two promising models have emerged: the STUMBL Score-based on age, number of rib fractures, chronic lung disease, pre-injury anticoagulant use, and oxygen saturation-is explicitly designed for blunt chest trauma prognosis. Studies report strong discriminatory performance, with development-phase c-index up to 0.96 . External validations vary: one UK cohort showed STUMBL ≥ 11 had a sensitivity of 79%, specificity of 78%, and AUC of 0.84-comparable to clinician judgment ; Italian data demonstrated excellent discrimination (C-index \~0.90) and calibration .

The Thoracic Trauma Severity Score (TTSS), initially validated in polytrauma ICU patients, yields moderate to good discrimination (c-indices 0.72-0.85) across validation studies .

Though these scores show promise, high methodological bias and limited external validations temper their widespread adoption . A direct, comparative analysis of STUMBL and TTSS within a well-defined patient cohort is thus needed.

Conditions

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Blunt Chest Wall Trauma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Blunt Chest Trauma group

The Blunt Chest Trauma Cohort comprises all consecutive adult patients (≥18 years) presenting with blunt chest trauma to the Emergency Department of Assiut university between October 2025 and October 2026. Patients meeting inclusion criteria will be enrolled prospectively and followed throughout their hospital stay to record clinical course and outcomes. At presentation both the STUMBL and TTSS scores will be calculated for each patient using standard definitions. The cohort will be analyzed as a single group to evaluate the predictive performance of each score for predefined outcomes (morbidity and mortality)

Chest X-Ray

Intervention Type DIAGNOSTIC_TEST

First-line imaging for suspected rib fractures, hemothorax, pneumothorax, or pulmonary contusion

Computed Tomography (CT) Chest (with or without contrast)

Intervention Type DIAGNOSTIC_TEST

Gold standard for detecting:

Rib fractures (especially multiple and posterior).

Pulmonary contusions and lacerations.

Hemothorax, pneumothorax, hemopericardium.

Pleural or mediastinal injuries

Interventions

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Chest X-Ray

First-line imaging for suspected rib fractures, hemothorax, pneumothorax, or pulmonary contusion

Intervention Type DIAGNOSTIC_TEST

Computed Tomography (CT) Chest (with or without contrast)

Gold standard for detecting:

Rib fractures (especially multiple and posterior).

Pulmonary contusions and lacerations.

Hemothorax, pneumothorax, hemopericardium.

Pleural or mediastinal injuries

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Adult patients (≥18 years) presenting with blunt chest trauma.
* Patients who have given written informed consent to participate in the study

Exclusion Criteria

* Penetrating chest injuries
* Pediatric patients (\<18 years)
* Patients with incomplete records or who decline consent
* Pregnant women
* Disturbed conscious patients
* Mechanically ventilated patients
* Polytrauma patients
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Emad Ahmed Swefy

Emergency medicine resident at Assiut University

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jehan Ahmed Sayed, Professor of Anathesia and ICU

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Yasmin Elsayed Mohamed Elbeltagy, Lecturer of emergency medicine

Role: STUDY_DIRECTOR

Seuz canal University

Central Contacts

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Mohamed Emad Ahmed Swefy, M.B.B.Ch

Role: CONTACT

+201061845700

References

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Seok J, Cho HM, Kim HH, Kim JH, Huh U, Kim HB, Leem JH, Wang IJ. Chest Trauma Scoring Systems for Predicting Respiratory Complications in Isolated Rib Fracture. J Surg Res. 2019 Dec;244:84-90. doi: 10.1016/j.jss.2019.06.009. Epub 2019 Jul 4.

Reference Type RESULT
PMID: 31279998 (View on PubMed)

Baddam S, Burns B. Systemic Inflammatory Response Syndrome. 2025 Jun 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK547669/

Reference Type RESULT
PMID: 31613449 (View on PubMed)

Callisto E, Costantino G, Tabner A, Kerslake D, Reed MJ. The clinical effectiveness of the STUMBL score for the management of ED patients with blunt chest trauma compared to clinical evaluation alone. Intern Emerg Med. 2022 Sep;17(6):1785-1793. doi: 10.1007/s11739-022-03001-0. Epub 2022 Jun 23.

Reference Type RESULT
PMID: 35739456 (View on PubMed)

Other Identifiers

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STUMBL-TTSS-BluntChestTrauma

Identifier Type: -

Identifier Source: org_study_id

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