STUMBL vs TTSS in Predicting Morbidity and Mortality of Blunt Chest Trauma
NCT ID: NCT07270354
Last Updated: 2025-12-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
124 participants
OBSERVATIONAL
2025-12-30
2026-12-30
Brief Summary
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Detailed Description
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Two promising models have emerged: the STUMBL Score-based on age, number of rib fractures, chronic lung disease, pre-injury anticoagulant use, and oxygen saturation-is explicitly designed for blunt chest trauma prognosis. Studies report strong discriminatory performance, with development-phase c-index up to 0.96 . External validations vary: one UK cohort showed STUMBL ≥ 11 had a sensitivity of 79%, specificity of 78%, and AUC of 0.84-comparable to clinician judgment ; Italian data demonstrated excellent discrimination (C-index \~0.90) and calibration .
The Thoracic Trauma Severity Score (TTSS), initially validated in polytrauma ICU patients, yields moderate to good discrimination (c-indices 0.72-0.85) across validation studies .
Though these scores show promise, high methodological bias and limited external validations temper their widespread adoption . A direct, comparative analysis of STUMBL and TTSS within a well-defined patient cohort is thus needed.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Blunt Chest Trauma group
The Blunt Chest Trauma Cohort comprises all consecutive adult patients (≥18 years) presenting with blunt chest trauma to the Emergency Department of Assiut university between October 2025 and October 2026. Patients meeting inclusion criteria will be enrolled prospectively and followed throughout their hospital stay to record clinical course and outcomes. At presentation both the STUMBL and TTSS scores will be calculated for each patient using standard definitions. The cohort will be analyzed as a single group to evaluate the predictive performance of each score for predefined outcomes (morbidity and mortality)
Chest X-Ray
First-line imaging for suspected rib fractures, hemothorax, pneumothorax, or pulmonary contusion
Computed Tomography (CT) Chest (with or without contrast)
Gold standard for detecting:
Rib fractures (especially multiple and posterior).
Pulmonary contusions and lacerations.
Hemothorax, pneumothorax, hemopericardium.
Pleural or mediastinal injuries
Interventions
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Chest X-Ray
First-line imaging for suspected rib fractures, hemothorax, pneumothorax, or pulmonary contusion
Computed Tomography (CT) Chest (with or without contrast)
Gold standard for detecting:
Rib fractures (especially multiple and posterior).
Pulmonary contusions and lacerations.
Hemothorax, pneumothorax, hemopericardium.
Pleural or mediastinal injuries
Eligibility Criteria
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Inclusion Criteria
* Patients who have given written informed consent to participate in the study
Exclusion Criteria
* Pediatric patients (\<18 years)
* Patients with incomplete records or who decline consent
* Pregnant women
* Disturbed conscious patients
* Mechanically ventilated patients
* Polytrauma patients
18 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Mohamed Emad Ahmed Swefy
Emergency medicine resident at Assiut University
Principal Investigators
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Jehan Ahmed Sayed, Professor of Anathesia and ICU
Role: PRINCIPAL_INVESTIGATOR
Assiut University
Yasmin Elsayed Mohamed Elbeltagy, Lecturer of emergency medicine
Role: STUDY_DIRECTOR
Seuz canal University
Central Contacts
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References
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Seok J, Cho HM, Kim HH, Kim JH, Huh U, Kim HB, Leem JH, Wang IJ. Chest Trauma Scoring Systems for Predicting Respiratory Complications in Isolated Rib Fracture. J Surg Res. 2019 Dec;244:84-90. doi: 10.1016/j.jss.2019.06.009. Epub 2019 Jul 4.
Baddam S, Burns B. Systemic Inflammatory Response Syndrome. 2025 Jun 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK547669/
Callisto E, Costantino G, Tabner A, Kerslake D, Reed MJ. The clinical effectiveness of the STUMBL score for the management of ED patients with blunt chest trauma compared to clinical evaluation alone. Intern Emerg Med. 2022 Sep;17(6):1785-1793. doi: 10.1007/s11739-022-03001-0. Epub 2022 Jun 23.
Other Identifiers
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STUMBL-TTSS-BluntChestTrauma
Identifier Type: -
Identifier Source: org_study_id
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