MCG In Long QT Syndrome

NCT ID: NCT07270211

Last Updated: 2025-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-01-31

Study Completion Date

2027-12-31

Brief Summary

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The primary objective of this observational study is to evaluate whether magnetocardiography (MCG) findings more accurately predict clinical outcomes in patients with acquired Long QT syndrome compared to ECG. The secondary objective is to assess differences in QT interval length between MCG and ECG. The primary safety objective is to characterize the safety profile of the CardiAQ MCG device.

Detailed Description

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Conditions

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Atrial Fibrillation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Subjects diagnosed with atrial fibrillation

Magnetocardiography

Intervention Type DIAGNOSTIC_TEST

MCG is a non-invasive, radiation-free imaging technique that detects the magnetic field generated by the electrical activity of the heart.

Interventions

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Magnetocardiography

MCG is a non-invasive, radiation-free imaging technique that detects the magnetic field generated by the electrical activity of the heart.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

1. Age ≥ 18 years on the date of consent
2. Ability for participant to comply with study requirements
3. Written informed consent
4. Confirmed diagnosis of atrial fibrillation and receiving dofetilide for rhythm control in the inpatient setting.

Exclusion Criteria

1. Pregnant or breastfeeding
2. Active thoracic metal implants (including pacemaker, insertable cardiac monitor, or internal defibrillators).
3. External electrical pads or devices (e.g. Pacer pads, ECG electrodes, heart rate patch), that must remain on patient's chest during MCG scan
4. Inability to lie down in a supine/inclined position and stay still on the examination bed
5. Clinical conditions that in the opinion of the Investigator would compromise the safety of the patient or ability to complete the protocol
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Mohamad Adnan Alkhouli

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mohamad Alkhouli, M.D., M.B.A.

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic in Rochester

Rochester, Minnesota, United States

Site Status

Countries

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United States

Central Contacts

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Patsy Caceres Figueroa

Role: CONTACT

507-266-3054

Facility Contacts

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Structural Heart Research Team

Role: primary

(507) 255-6133

Other Identifiers

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25-008283

Identifier Type: -

Identifier Source: org_study_id

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