Survey of Practices Regarding the Use of Taurolidine Lock Solutions in Patients With Insertion of a Peripherally Inserted Central Catheter (PICC) in a Vascular Access Unit

NCT ID: NCT07259421

Last Updated: 2025-12-02

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 45 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-12-31
• Study Completion Date: 2026-03-31

Brief Summary

The primary objective of this study is to describe current practices regarding the administration of taurolidine lock solutions in relation to medical prescriptions for patients who have undergone peripherally inserted central catheter (PICC) implantation in the Vascular Access Unit as part of parenteral nutrition therapy. Our underlying hypothesis is that the use of taurolidine lock solutions may deviate from current recommendations, particularly with respect to administration procedures.

This study will allow us to characterize the use of taurolidine lock solutions in relation to medical prescriptions, identify potential deviations from recommended practices, and document any associated adverse events. It will also enable follow-up of PICC outcomes at 8 and 30 days after implantation in the Vascular Access Unit, whereas current follow-up is performed only at 8 days post-insertion.

Conditions

Taurolidine Lock Solution

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Patient who has undergone PICC placement in the vascular access unit with an indication for parenteral nutrition supplementation.
• Patient not opposed to participating in this research.

Exclusion Criteria

• Patient not speaking French
• Patient under guardianship or conservatorship
• Patient with major neurocognitive disorders
• Patient with severe hearing impairment
• Patient who do not have a telephone

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Grenoble

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Central Contacts

Cordélia SALOMEZ-IHL, pharmacist

Role: CONTACT

cihl@chu-grenoble.fr

+ 33 (0)4 76 76 85 27

Aida MANDZO, clinical research associate

Role: CONTACT

amandzo@chu-grenoble.fr

+33 (0)4 76 76 68 16

Other Identifiers

38RC25.0315.

Identifier Type: -

Identifier Source: org_study_id