Pilot Study, Aimed at Describing in Myography, the Collapse of the Muscular Response Visualized in the Scratch Collapse Test, in Carpal Tunnel Syndrome.

NCT ID: NCT07248124

Last Updated: 2025-11-25

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 25 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-11-04
• Study Completion Date: 2026-05-05

Brief Summary

The Scratch Collapse Test (SCT) is a neurocutaneous reflex used to detect peripheral nerve compression in nerve tunnel syndromes. It first involves applying a sensory stimulus to the skin over the suspected nerve compression point, then bilaterally testing the strength of a specific muscle in the patient. Compression is then manifested by a transient loss of strength in the muscle on the affected side, while it is preserved on the healthy side. This loss of strength is transient and disappears after a few seconds. This test can be performed during a patient's clinical examination, with the physician assessing strength or, conversely, muscle collapse. However, while several articles have described the relevance of this test, as well as its sensitivity and specificity, no study has specifically investigated and measured this observed loss of eccentric muscle tone and its unilateral and transient nature, even though the phenomenon of CSP (cutaneous silent period) has been described.

We therefore propose to analyze the myographic tracing obtained in patients diagnosed with unilateral carpal tunnel syndrome. A transient loss of muscle tone is expected by selective needle myography on the pathological side after cutaneous sensory stimulation of the wrist, while cutaneous sensory stimulation on the healthy side does not alter the tracings obtained by myography.

Conditions

Carpal Tunnel Syndrome (CTS)

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Patient with unilateral carpal tunnel syndrome

Patient with clinical unilateral carpal tunnel syndrome diagnosed by history, clinical examination and electromyography,

Group Type: EXPERIMENTAL

electromyograph

Intervention Type: PROCEDURE

This examination uses electrodes placed along the path of the median nerve to measure the transmission of nerve impulses (conduction studies). It is performed on both hands to compare the results.

Scratch Collapse Test

Intervention Type: DIAGNOSTIC_TEST

The Scratch Collapse Test (SCT) is a neurocutaneous reflex used to detect peripheral nerve compression in nerve canal syndromes. It involves first performing a sensory stimulus on the skin at the suspected nerve compression site, then bilaterally testing the strength of a specific muscle in the patient. Compression is then manifested by a transient loss of strength in the muscle on the affected side, while it is preserved on the stimulated side.

Interventions

electromyograph

This examination uses electrodes placed along the path of the median nerve to measure the transmission of nerve impulses (conduction studies). It is performed on both hands to compare the results.

Intervention Type: PROCEDURE

Scratch Collapse Test

The Scratch Collapse Test (SCT) is a neurocutaneous reflex used to detect peripheral nerve compression in nerve canal syndromes. It involves first performing a sensory stimulus on the skin at the suspected nerve compression site, then bilaterally testing the strength of a specific muscle in the patient. Compression is then manifested by a transient loss of strength in the muscle on the affected side, while it is preserved on the stimulated side.

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• Patient over 18 years old
• Patient with clinical unilateral carpal tunnel syndrome diagnosed by history, clinical examination and electromyography,
• Patient who has been informed and has given their free, informed, and written consent,
• Patient affiliated with or beneficiary of a social security scheme.

Exclusion Criteria

• Other associated canal syndrome on either side (ulnar, defilement, lacertus),

• Rotator cuff pathology, insufficiency or rupture of the infraspinatus,
• Associated cervical pathology,
• Neuropathy, central or peripheral neurological disease,
• Diabetic patient,
• Patient with cognitive impairments that prevent the understanding of the study information,
• Refusal to participate in the study,
• Pregnant, parturient, or breastfeeding woman,
• Patient under legal protection,
• Patient not receiving health protection,
• Protected patient: adult under guardianship, curatorship, or other legal protection, deprived of liberty by judicial or administrative decision

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Elsan

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Clinique de l'Ormeau

Tarbes, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Vincent Martinel, Dr

Role: CONTACT

drvmartinel@goop65.fr

0033562563895

Facility Contacts

Vincent Marinel, Dr

Role: primary

drvmartinel@goop65.fr

0033562563898

Other Identifiers

2025-A01019-40

Identifier Type: OTHER

Identifier Source: secondary_id

SC-My

Identifier Type: -

Identifier Source: org_study_id